• Journal of Animal Science and Technology
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• 제64권3호
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• pp.588-598
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• 2022

Despite vaccination, equine influenza virus (EIV) and equine herpesvirus (EHV) infections still cause highly contagious respiratory diseases in horses. Recently, concurrent vaccination with EIV and EHV was suggested as a new approach; however, there have been no reports of concurrent vaccination with recombinant canarypox EIV and inactivated EHV vaccines. In this study, we aimed to compare the EIV-specific immune responses induced by concurrent administrations of a recombinant canarypox EIV vaccine and an inactivated bivalent EHV vaccine with those induced by a single recombinant canarypox EIV vaccine in experimental horse and mouse models. Serum and peripheral blood mononuclear cells (PBMCs) were collected from immunized animals after vaccination. EIV-specific serum antibody levels, serum hemagglutinin inhibition (HI) titers, and interferon-gamma (IFN-γ) levels were measured by enzyme-linked immunosorbent assay, HI assay, and quantitative polymerase chain reaction, respectively. Concurrent EIV and EHV vaccine administration significantly increased IFN-γ production, without compromising humoral responses. Our data demonstrate that concurrent vaccination with EIV and EHV vaccines can enhance EIV-specific cellular responses in horses.

• 한국동물위생학회지
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• 제46권4호
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• pp.263-268
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• 2023

Despite regular vaccinations, equine influenza virus (EIV) and Streptococcus equi subsp. equi (strangles) are the cause of highly contagious respiratory infections in horses. Many recent studies have reported that the concurrent administration of two vaccines could simplify horse management and minimize veterinary expenses. However, there is little information available regarding the efficacy of concurrent vaccinations against EIV and strangles. In this study, we evaluated EIV-specific antibody responses following the single EIV vaccination with the recombinant viral-vectored EIV vaccine or concurrent vaccination with the EIV and inactivated strangles vaccines. Blood samples were collected at 1-, 2-, 4-, and 8 weeks post-immunization (wpi) from each group. EIV-specific antibodies were evaluated by enzyme-linked immunosorbent assay (ELISA) and hemagglutination inhibition (HAI) assay. Both single and concurrent vaccination showed similar levels of EIV-specific serum immunoglobulin g (IgG) at 1 and 2 wpi. However, at 4 to 8 wpi, the EIV-only vaccination group showed significantly higher serum IgG levels than those from the concurrently vaccinated group. The HAI titers showed similar trends as the ELISA data, except at 8 wpi when both groups presented HAI titers with no significant differences. These data demonstrate that the concurrent vaccination against EIV and strangles could compromise the humoral immune response to equine influenza between vaccination intervals, which suggests the use of the consecutive vaccination protocol for EIV and strangles rather than concurrent vaccination.

• 전기의세계
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• 제36권12호
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• pp.892-898
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• 1987

본고에서는 일반적으로 많이 사용하는 방법들인 ELS, RML, EIV 등을 소개하고 더 정확한 추정을 위해서 과결정 확장기구 변수법(OEIV;Overdetermined EIV)을 소개하며 이를 격자구조를 이용해서 실현한 격자구조 확장기구변수법(LEIV;Lattice EIV)을 소개하였다.

• Journal of Microbiology and Biotechnology
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• 제25권3호
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• pp.317-320
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• 2015

H3N8 equine influenza virus (EIV) causes respiratory diseases in the horse population, and it has been demonstrated that EIV can transmit into dogs owing to its availability on receptors of canine respiratory epithelial cells. Recently, we isolated H3N8 EIV from an EIV-vaccinated horse that showed symptoms of respiratory disease, and which has a partially truncated nonstructural gene (NS). However, it is not clear that the NS-truncated EIV has an ability to cross the host species barrier from horses to dogs as well. Here, we experimentally infected the NS-truncated H3N8 EIV into dogs, and monitored their clinical signs and viral load in respiratory organs to determine the virus's transmissibility.

• 한국통신학회논문지
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• 제39C권10호
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• pp.887-895
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• 2014

졸음운전은 전체 교통사고 원인 중 큰 비중을 차지하며 그 위험성이 음주운전보다도 크다고 알려져 있다. 따라서 운전자의 졸음을 판단하고 경고하는 시스템 개발에 대한 관심이 높아지고 있으며, 뇌파를 분석하는 것이 운전자의 피로와 졸음을 감지하는데 효과적이라는 연구결과들이 발표되었다. 본 논문은 짧은 시간에 높은 해상도를 가지는 auto-regressive 모델 기법 중 잡음에 강인한 errors-in-variables(EIV) 방법을 이용하여 특징벡터를 추출하고, 다층신경망(multilayer perceptron; MLP)에 적용하여 운전자의 상태를 각성, 천이, 졸음의 세 가지 상태로 분류하는 졸음 감지 시스템을 제안한다. 생체신호의 측정 환경에 따른 성능을 평가하기 위해 높은 진단률을 갖도록 하는 EIV차수를 결정하고, 잡음에 대한 강인성을 확인하기 위해 신호대 잡음비(signal-to-noise ratio; SNR)에 따른 성능을 선형 예측 부호화(linear predictive coding; LPC) 방법과 비교하였다. 이 결과로부터 제안한 EIV와 MLP를 결합한 졸음 감지 시스템은 기존의 LPC와 MLP를 이용한 시스템에 대해 우수한 성능을 얻을 수 있음을 확인하였다.

• 한국소음진동공학회논문집
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• 제21권11호
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• pp.1020-1028
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• 2011

As rotating machines play an important role in industrial applications such as aeronautical, naval and automotive industries, many researchers have developed various condition monitoring system and fault diagnosis system by applying artificial neural network. Since using obtained signals without preprocessing as inputs of neural network can decrease performance of fault classification, it is very important to extract significant features of captured signals and to apply suitable features into diagnosis system according to the kinds of obtained signals. Therefore, this paper proposes a neural-network-based fault diagnosis system using AR coefficients as feature vectors by LPC(linear predictive coding) and EIV(errors-in variables) analysis. We extracted feature vectors from sound, vibration and current faulty signals and evaluated the suitability of feature vectors depending on the classification results and training error rates by changing AR order and adding noise. From experimental results, we conclude that classification results using feature vectors by EIV analysis indicate more than 90 % stably for less than 10 orders and noise effect comparing to LPC.

• 대한전기학회논문지
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• 제39권3호
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• pp.312-320
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• 1990

Analysis and lattice implementation of Extended Instrumental Variable (EIV) methods for high resolution spectral analysis are presented. The performance of EIV is improved by using prefilters and the unbiasness of EIV is proved by using the fact that residual processes are white. We derive the order and time update formulas for the covariance lattice algorithm which is particularly useful in case of short data or nonstationary processes. The ARMA model can be modeled as two channel AR processes. Using this model, the lattice algorithms of EIV are derived. Computer simulations are performed to show the usefulness of the proposed algorithms.

• 대한수의학회지
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• 제59권3호
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• pp.151-155
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• 2019

Equine influenza (EI) is the main cause of respiratory illness in equines across the globe and is caused by equine influenza A virus (EIV-A), which has impacted the equine industry internationally because of the marginal mortality and high morbidity. In the present study, the immune responses after equine influenza vaccination were evaluated in 4,144 horses in Korea using the hemagglutination inhibition (HI) assay. The equine influenza virus (EIV), A/equine/South Africa/4/03 (H3N8), was used as the antigen in the HI assay. The mean seropositive rates were 89.2% (97.4% in 2016, 77.6% in 2017, and 92.4% in 2018). This paper highlights the advances in understanding the effects of vaccines and control strategies for mitigating the emerging menace by EIV.

• 자원리싸이클링
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• 제10권2호
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• pp.50-53
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• 2001

• 한국통신학회논문지
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• 제40권9호
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• pp.1731-1733
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• 2015

뇌파는 비선형적이고 비정상적인 특징을 가지므로 주파수 분석법보다는 시간-주파수 분석법을 적용하는 것이 효과적이다. 본 논문은 기존에 제안했던 EIV 기법과 다층신경망을 이용한 뇌파기반 졸음 감지 시스템에 시간-주파수 분석 방법인 이산 웨이블릿 변환을 적용한 졸음 감지 시스템을 제안한다. 또한 운전자의 상태를 기존의 '각성', '천이', '졸음'의 세 가지 상태에 '기타'를 추가하여 네 가지 상태로 분류율을 측정하였으며, 기계 학습을 수행하여 제안한 시스템이 특정 조건에서 우수한 성능을 가짐을 확인하였다.