In this study, the in situ deformation moduli, which were measured by borehole loading tests at basaltic rock masses located in the northeastern onshore and offshore and the northwestern onshore of Jeju Island, were examined in relation to RQD and RMR. The measured deformation moduli were also compared with the estimated deformation moduli from conventional empirical formulas using RQD and RMR. In addition, the measured deformation moduli were analyzed with respect to both the velocity ratio ($V_P/V_S$) and dynamic Poisson's ratio, which were obtained from the elastic wave velocities measured by velocity logging tests. As results, with only RQD, it was inappropriate to evaluate the quality of the Jeju island basaltic rock masses, which are characterized by vesicular structures, to select a measurement method of in situ deformation moduli, and to estimate the deformation moduli. On the other hand, it was desirable to evaluate the quality of the Jeju Island basaltic rock masses, and to estimate the deformation moduli by using RMR. The conventional empirical formulas using RMR overestimated the deformation moduli of the Jeju Island basaltic rock masses. There was qualitative consistency in the relation between velocity ratio and deformation moduli. To estimate appropriately the deformation moduli of the Jeju Island basaltic rock masses, empirical formulas were proposed as the function of RMR and velocity ratio, respectively.
Ma, Claudia C.;Hartley, Tara A.;Sarkisian, Khachatur;Fekedulegn, Desta;Mnatsakanova, Anna;Owens, Sherry;Gu, Ja Kook;Tinney-Zara, Cathy;Violanti, John M.;Andrew, Michael E.
Safety and Health at Work
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v.10
no.1
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pp.30-38
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2019
Background: Police officers' stress perception, frequency of stressful events (stressors), and police work characteristics may contribute to poor sleep quality through different mechanisms. Methods: We investigated associations of stress severity (measured by stress rating score) and frequency of stressors with sleep quality and examined the influence of police work characteristics including workload, police rank, prior military experience, and shift work on the associations. Participants were 356 police officers (256 men and 100 women) enrolled in the Buffalo Cardio-Metabolic Occupational Police Stress Study from 2004 to 2009. A mean stress rating score and mean frequency of stressors occurring in the past month were computed for each participant from the Spielberger Police Stress Survey data. Sleep quality was assessed using the global score derived from the Pittsburgh Sleep Quality Index survey. Linear associations of the stress rating score and frequency of stressors with sleep quality (Pittsburgh Sleep Quality Index global score) were tested. Age, sex, race/ethnicity, and smoking status were selected as potential confounders. Results: The stress rating score was positively and independently associated with poor sleep quality (${\beta}=0.17$, p = 0.002). Only workload significantly modified this association (${\beta}=0.23$, p = 0.001 for high workload group; p-interaction = 0.109). The frequency of stressors was positively and independently associated with poor sleep quality (${\beta}=0.13$, p = 0.025). Only police rank significantly modified the association (${\beta}=0.007$, p = 0.004 for detectives/other executives; p-interaction = 0.076). Conclusion: Both police officers' perception of stress severity and the frequency of stressors are associated with poor sleep quality. Stress coping or sleep promotion regimens may be more beneficial among police officers reporting high workloads.
Kim, Sewon;Park, Jun Kyung;Lee, Sangjun;Kim, YoungSeok
Journal of Korean Tunnelling and Underground Space Association
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v.23
no.2
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pp.77-92
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2021
For the construction of a large underground space with a complex plant installed, it is necessary to analyze the stability considering the ground conditions and various load conditions. In this paper, finite element analysis was performed to analyze the support load that can be used in the design of a large underground space for high-density arrangement of complex plant. An analysis of underground continuous wall (D-wall) was performed considering the load and horizontal earth pressure in the large underground space. In addition, foundation ground analysis was carried out according to the load condition of the complex plant. In order to shorten the construction period, increase the space layout utilization, and secure the stability of the plant structure when installing the complex plant underground, the pipe rack module structure analysis was conducted. This study proposes a design and construction method for the optimal arrangement of underground complex plants using the analysis results.
This experiment was performed to verify whether dietary heat-killed Lactobacillus rhamnosus (LR) improves growth performance and modulates immune responses of weaned pigs. Ninety-six weaned pigs ([Landrace × Yorkshire] × Duroc; 6.95 ± 0.25 kg body weight [BW]; 28 d old) were randomly allocated to four treatments: 1) a basal diet without heat-killed LR (CON), 2) T1 (CON with 0.1% heat-killed LR), 3) T2 (CON with 0.2% heat-killed LR), and 4) T3 (CON with 0.4% heat-killed LR). Each treatment had six pens with four pigs (6 replicates per treatment) in a randomized completely block design. The heat-killed LR used in this study contained 1 × 109 FU/g of LR in a commercial product. Pigs were fed each treatment for four weeks using a two-phase feeding program to measure growth performance and frequency of diarrhea. During the last week of this study, all diets contained 0.2% chromic oxide as an indigestible marker. Fecal sampling was performed through rectal palpation for the consecutive three days after the four adaptation days to measure apparent total tract digestibility (ATTD) of dry matter, crude protein, and gross energy (GE). Blood sampling was also performed on day 1, 3, 7, and 14 after weaning to measure immune responses such as serum tumor necrosis factor-α (TNF-α), transforming growth factor-β1 (TGF-β1), C-reactive protein (CRP), and cortisol. The heat-killed LR increased (p < 0.05) growth rate, feed efficiency, and ATTD of GE for overall experimental period compared with CON, but reduced (p < 0.05) post-weaning diarrhea. In addition, pigs fed diets contained heat-killed had lower concentrations of serum TNF-α (d 7; p < 0.05), TGF-β1 (d 7; p < 0.10), and cortisol (d 3 and 7; p < 0.05) than pigs fed CON. In conclusion, dietary heat-killed LR improved growth rate, modified immune responses of weaned pigs, and alleviated post-weaning diarrhea.
Journal of Korean Tunnelling and Underground Space Association
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v.23
no.5
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pp.339-357
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2021
As the construction of trans infrastructure using the underground tunnel have been rapidly increased, various nearby excavation of existed underground facility including subway structure has been occurred in urban tunnelling. The concern and worry relating to the safety and stability of the existed facility by nearby excavation is becoming the key issues in urban tunnelling. In this study, it was conducted for existed the subway station structure at Seoul subway line which was closely located in the new Dongbuk urban metro railway to determine the behavior characteristics of station structure according to adjacent tunnel construction. Also, it was reviewed the evaluation of the safety zone and excavation method for subway structure. And after a review of damage evaluation, track irregularities and structural calculation by using a numerical analysis, stability of the subway structure according to nearby tunnel excavation was evaluated to be secured. This study is expected to be applied as useful reference in advance if you need to review the effects of existed structure according to nearby construction in complex urban tunnelling.
Clinker layer is a stratum structure distributed in volcanic area such as Jeju Island. The clinker layers were formed in between the repetitive action of eruption and solidification of lava flows. Since the clinker layer contains a large amount of voids accompanied by the lava gas ejection process, there is a possibility of inducing overall stability of the ground due to the low stiffness and strength of the clinker layer. Therefore, in this study, site investigation was carried out at both ends of the 00 bridge where the clinker layers exist. And, based on the ground survey results, the behavior of shallow foundations was analyzed numerically. In addition, the improved shallow foundation behavior in grouting substitution using the chemical injection method of the clinker layer was compared with the shallow foundation behavior in the ground, and the grouting substitution efficiency of each layer was analyzed. As a result, the bearing capacity, the replacement efficiency and elastic settlement were different according to the presence or absence of the sediment layer. This is because the sediment layer has a lower stiffness and density than the clinker layer.
Kim, Dong-Hun;Moon, Sang-Ho;Ko, Kyung-Seok;Kim, Sunghyun
Economic and Environmental Geology
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v.53
no.6
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pp.655-666
/
2020
This study evaluated the characteristics of arsenic production in groundwater through microbial community analysis of groundwater contaminated with high arsenic in Haman area. Groundwater in Haman area is contaminated with arsenic in the range of 0-757.2 ㎍/L, which represents the highest arsenic contamination concentration reported in Korea as natural groundwater pollution source. Of the total 200 samples, 29 samples (14.5%) showed higher arsenic concentration than that of 10 ㎍/L, which is the standard for drinking water quality, and 8 samples (4%) found in wells with 80-100 m depth were above 50 ㎍/L. In addition, seven wells with arsenic concentration more than 100 ㎍/L located in the northern part of Haman. As a result of microbial community analysis for high arsenic-contaminated groundwater, the microbial community compositions were significantly different between each sample, and Proteobacteria was the most dominant phyla with an average of 61.5%. At the genus level, the Gallinonella genus was predominant with about 12.8% proportion, followed by the Acinetobacter and Methermicoccus genus with about 7.8 and 7.3%, respectively. It is expected that high arsenic groundwater in the study area was caused by a complex reaction of geochemical characteristics and biogeochemical processes. Therefore, it is expected that the constructed information on geochemical characteristics and microbial communities through this study could be used to identify the origin of high arsenic groundwater and the development of its controlling technology.
Korean Journal of Construction Engineering and Management
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v.22
no.1
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pp.55-62
/
2021
The productivity of rebar-work and form-work was analyzed with data collected from an actual high-rise construction project, and the actual utilization rates of three tower cranes were also investigated. It was found that the average productivity of the form-work increased from 12.00~8.71(㎡/man·day) in the underground and above-ground/lower-floor to 11.94~20.73(㎡/man·day) in the standard floor. Comparing the productivity of core area to outer, the former was found to be about 11% higher. Moreover, the rebar-work productivity of the outer area(1.12 ton/man·day) was approximately 9.6% higher than that of the core area for the standard floor. The average utilization rates of three TC were surveyed to be about 63.49%, and it was revealed that rainy weather(6.1%), strong winds(6.1%), holidays(17.8%), TC lifting work(5.8%), and other failures and repairs(0.07%) were the causes of non-operation. These research results are expected to be beneficial data in planning and managing the process of high-rise RC construction works in the future.
Jeong, Kyoungyun;Kong, Seong-Ho;Bae, Seong-Woo;Park, Cho Rong;Berlth, Felix;Shin, Jae Hwan;Lee, Yun-Sang;Youn, Hyewon;Koo, Eunhee;Suh, Yun-Suhk;Park, Do Joong;Lee, Hyuk-Joon;Yang, Han-Kwang
Journal of Gastric Cancer
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v.21
no.2
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pp.191-202
/
2021
Purpose: A near-infrared (NIR) fluorescence imaging is a promising tool for cancer-specific image guided surgery. Human epidermal receptor 2 (HER2) is one of the candidate markers for gastric cancer. In this study, we aimed to synthesize HER2-specific NIR fluorescence probes and evaluate their applicability in cancer-specific image-guided surgeries using an animal model. Materials and Methods: An NIR dye emitting light at 800 nm (IRDye800CW; Li-COR) was conjugated to trastuzumab and an HER2-specific affibody using a click mechanism. HER2 affinity was assessed using surface plasmon resonance. Gastric cancer cell lines (NCI-N87 and SNU-601) were subcutaneously implanted into female BALB/c nu (6-8 weeks old) mice. After intravenous injection of the probes, biodistribution and fluorescence signal intensity were measured using Lumina II (Perkin Elmer) and a laparoscopic NIR camera (InTheSmart). Results: Trastuzumab-IRDye800CW exhibited high affinity for HER2 (KD=2.093(3) pM). Fluorescence signals in the liver and spleen were the highest at 24 hours post injection, while the signal in HER2-positive tumor cells increased until 72 hours, as assessed using the Lumina II system. The signal corresponding to the tumor was visually identified and clearly differentiated from the liver after 72 hours using a laparoscopic NIR camera. Affibody-IRDye800CW also exhibited high affinity for HER2 (KD=4.71 nM); however, the signal was not identified in the tumor, probably owing to rapid renal clearance. Conclusions: Trastuzumab-IRDye800CW may be used as a potential NIR probe that can be injected 2-3 days before surgery to obtain high HER2-specific signal and contrast. Affibody-based NIR probes may require modifications to enhance mobilization to the tumor site.
Since the development of Smart technology and the advent of various Smart media, a learning environment for individual learners and the school has been changing. In the stream of changing learning environments, in 2011, the government announced SMART education strategies, introducing the term officially, "SMART education." With the governments' efforts to develop and implement SMART education in school, many policies has been enacted and many research has been conducted and increased gradually. However, as policies of SMART education have initiated in situation where there is no clear understanding in regard of SMART education, many researchers and teachers confused of SMART education and its identity and attributes, even though it has been 6 years since the concept was introduced. Unfortunately, SMART education has been implemented as one type of instructional methodology as utilizing Smart technology. Thus, in this research, we tried to build theoretical foundation of SMART education through analyzing former research on SMART education to define the attributes of SMART education. To examine how SMART education has been implemented in terms of its attributes, also, we analyzed research that conducted instructional design and implementation on SMART education in actual learning environments. As the results of former research analysis, the attributes of SMART education include Information and Communication Technology, open learning environment, self-directed learning, customized learning, and social learning. In majority of research, SMART education focused on utilizing Smart technology and media in teaching and learning environments but self-directed, and customized learning were less adapted in SMART learning environments. In the following research, how to improve educational benefits of SMART education through adapting original attributes of SMART education need to be examined.
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