• Journal of Veterinary Clinics
• /
• v.28 no.5
• /
• pp.516-518
• /
• 2011

A survey was conducted to examine the normal intestinal bacterial flora of captive Oriental white storks (Ciconia boyciana) maintained at the Korea Institute of Oriental White Stork Rehabilitation Research, Cheongwon, South Korea. From the cloaca of 44 healthy storks, 44 fecal samples were collected and cultured under aerobic and anaerobic conditions. The 16S ribosomal RNA gene sequences and the heat shock protein 60 gene were cloned and sequenced for bacterial identification. Under aerobic conditions, Enterococcus faecalis, Escherichia coli, Bacillus spp., Enterococcus avium, Enterococcus gallinarum, Pseudomonas spp., Alcaligenes spp., Enterobacter spp., Corynebacterium spp., and Proteus mirabilis were identified. Under anaerobic conditions, E. coli, Clostridium tertium, En. faecalis, and P. mirabilis were identified. E. coli, En. faecalis, or both were isolated from all samples. These results will add to the information available on this stork species and help for the interpretation of fecal culture results.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.9
• /
• pp.4013-4018
• /
• 2014

Because of its importance in tumor invasion and metastasis, the epithelial-mesenchymal transition (EMT) has become a research focus in the field of cancer. Recently, evidence has been presented that FoxO4 might be involved in EMT. Our study aimed to detect the expression of FoxO4, E-cadherin and vimentin in non-small cell lung cancers (NSCLCs). We also investigated clinical features and their correlations with the markers. In our study, FoxO4, E-cadherin and vimentin were assessed by immunohistochemistry in a tissue microarray (TMA) containing 150 cases of NSCLC. In addition, the expression level of FoxO4 protein was determined by Western blotting. The percentages of FoxO4, E-cadherin and vimentin positive expression in NSCLCs were 42.7%, 38.7% and 55.3%, respectively. Immunoreactivity of FoxO4 was low in NSCLC when compared with paired normal lung tissues. There were significant correlations between FoxO4 and TNM stage (P<0.001), histological differentiation (P=0.004) and lymph node metastasis (P<0.001), but no significant links with age (P=0.323), gender (P=0.410), tumor size (P=0.084), smoking status (P=0.721) and histological type (P=0.281). Our study showed that low expression of FoxO4 correlated with decreased expression of E-cadherin and elevated expression of vimentin. Cox regression analysis indicated FoxO4 to be an independent prognostic factor in NSCLC (P=0.046). These data suggested that FoxO4 might inhibit the process of EMT in NSCLC, and might therefore be a target for therapy.

• The Research Journal of the Costume Culture
• /
• v.20 no.5
• /
• pp.621-634
• /
• 2012

With comparative analysis of running-type brassieres on the market about suitability for middle-aged women, this study is to provide basic data of running-type brassieres' pattern which is highly suitable. In the pursuit of this purpose, this study carried out wearing experiment targeting 3 middle-aged women with normal body shape which is 85B of chest circumference. The result is as follows. The significant difference was recognized in the breast. The products were rated in order of C>A>B>D, E, F, G>H by the observers, and C>B>D>A>F>E=G>H by the subjects. The significant difference was recognized in the armhole area. The products were ranked in the order of C, D>B, G, E>A, F, H by the observes and D, C>B>G>F>A>H by the subjects. The significant difference was also recognized in 6 categories(14~19) for the torso. According to the overall average values, the products were rated in the order of B, C, D>A, D, F, G by the observers and B=D>C>H>F>G>A>E by the subjects. The overall evaluation exhibited the significant difference. The products were ranked in the order of D>C>E>B>H>A>G>F by both observers and subjects. Therefore it was confirmed that the product D was appropriate in general. To conclude of comparative analysis about 8 kinds of running-type brassieres on the market, the average values of the product C and D in all categories had high marks for each category. The product C was comfortable and capable of covering the breast well, however, a gap was formed in outside-up part. The product D, made from lacy fabric, was very comfortable and well-fitted but there was inconsistency between the mold-cup and the breast shape.

• Journal of the Korean Applied Science and Technology
• /
• v.29 no.2
• /
• pp.175-183
• /
• 2012

This study was evaluated the antiatopic activity of cream containing a herb extracts mixed with Houttuynia cordata in DNCB-induced BALB/c atopy mouse. The randomized complete block design was done by BALB/c mouse into two groups, of which the control group with atopy and the cream treatment group. It was found that each level of IgE and histamine in blood was significantly decreased in the cream treatment group, compared with the DNCB-induced atopy control group. When the cream was applied to the atopy mouse, it could be observed that its skin recovered to normal condition with the skin surface being clean and smooth without any horny tissue. The results suggest that the application of herb extracts mixed with Houttuynia cordata has an antiatopic activity through a inhibition of histamin emissions with reducing the levels of blood IgE in BALB/C atopy mouse.

• Environmental Analysis Health and Toxicology
• /
• v.24 no.2
• /
• pp.169-178
• /
• 2009

To investigate the inhibitory effects of Peonia japonica water extract(PJWE) on skin wrinkle formation, skin wrinkles were induced by both the irradiation of UVB and the application of squalene monohydroperoxide to the backs of hairless mice for 4 weeks. And at the same time experimental materials were applied topically. Wrinkles for the control (C) group were formed as a pattern of deep furrows and thick crests. Whereas wrinkles for the positive control (PC, 0.01% retinoic acid) and experimental(E, PJWE) groups were formed as a pattern of shallow furrows and thin crests, which were similar to that of the normal(N) group. Collagen and elastic fibers in dermis of the PC and E groups were almost intact with a regular arrangement, which were similar to those of the N group. The activity of xanthine oxidase, the free radical generating enzyme, was significantly lower in the E group than the C and PC groups. The activities of superoxide dismutase and catalase, the free radical scavenging enzymes, were much higher in the E group than the C and PC groups and similar to the N group. As for the amount of matrix metalloproteinase-3(MMP-3) expression, PC and E groups were significantly lower than the C group. Therefore, PJWE could be very effective natural herbal material for the inhibition or improvement of wrinkle formation in hairless mice skin.

• Journal of Environmental Science International
• /
• v.5 no.5
• /
• pp.619-633
• /
• 1996

Intraseasonal variability of the tropical convection over the Indian/western Pacific is studied using the Geostationary Meteorological Satellite high cloud amount. This study is directed to find the tropical-extratropical interaction in the frequency range of intraseasonal and interannual variabilities of the summer monsoon occured over the domain of 90E-171W and 495-50N. Especially, in order to investigate the intraseasonal interaction of last Asia summer monsoon associated with the tropical convections in the high cloud amounts, the spatial and time structure of the intraseasonal oscillation for the movement-and the evolution of the large-scale connections are studied. To describe the spatial and the time evolution, the extended empirical orthogonal function analysis is applied. The first mode may be considered to a normal structure, indicating that the strong convection band over 90E-120E is extended to sastward but this mode was detected as the intraseasonal variability during summer monsoon. It is found that the dominant intraseasonal mode of the tropical convection consists of the spatial changes over a broad period range centered around 40~50days.

• Journal of Oriental Neuropsychiatry
• /
• v.29 no.3
• /
• pp.121-134
• /
• 2018

Objectives: The purpose of this in vivo study is to observe anti-amnesic effects of Yeongkyekamjotanggayonggolmoryo (YGYM), a novel mixed herbal prescription, Ossis Mastodi and Ostreae Testa added Yeongkyekamjo-tang, on scopolamine induced amnesia in C57BL/6 mice through acetylcholine (ACh) and acetylcholinesterase (AChE) activity, Choline acetyltransferase (ChAT) mRNA expression, and antioxidant effects. Methods: Six groups, total 20 intact or 100 Sco treated mice were used in this study after one week of acclimatization period. Half the animals were used for passive avoidance task tests and hippocampus ACh content, AChE activity, and ChAT mRNA expression were measured. The other half was subjected to an underwater maze test and then the cerebral cortex antioxidant defense system was measured. Results: In the passive avoidance experiment, there was significant decrease in residence time in the bright room and in the underwater maze test, escape latency to escape from the esophagus significantly increased compared with the normal control group. At the final sacrifice, ACh content and ChAT mRNA expression decreased, AChE activity increased, and cerebral cortical MDA increased GSH content, SOD and CAT activity in Sco control mice, as compared to intact vehicle control mice. However, these Sco treatment-related memory loss through AChE activation destroyed the cerebral cortex antioxidant defense system, and was inhibited dose-dependently by 28 days consecutive oral pretreatments of YGYM extracts 500, 250, 125 mg/kg. Conclusions: In the above results, YGYM extract that oral administration of YGYM extracts alleviates the antioxidant defense system, through preservation of ACh mediated by upregulation of ChAT mRNA expression, and increase of AChE inhibition and brain antioxidant defense systems.

• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.41 no.6 s.324
• /
• pp.17-24
• /
• 2004

This paper proposes an efficient technique to protect e-mail server from DDoS attack using the CBQ (Class Based Queuing) algorithm The proposed method classifies incoming trafic to an e-mail server into three classes: 'more important mail traffic', 'less important traffic' and 'unknown traffic' and assigns bandwidths differently to the traffics. By differentiating the bandwidths of classes, normal mail traffic may flow even under DDoS attack in the proposed technique. The proposed technique is implemented on an embedded system which hires a switching processor with the WFHBD(Weighted Fair Hashed Bandwidth Distribution) engine that has been known as an efficient algorithm to distribute a given bandwidth to multiple sources, and it is verified that it can be an efficient way to protect e-mail server from DDoS attack.

• Asian-Australasian Journal of Animal Sciences
• /
• v.21 no.1
• /
• pp.29-34
• /
• 2008

The aim of the study was to investigate the effect of dietary fish oil supplementation on the semen characteristics of the Markhoz buck. Sixteen bucks were randomly allocated into 4 groups and received four different diets: unsupplemented control diet, supplemented with fish oil at 2.50% dry matter (DM), supplemented with fish oil (2.50% DM) and vitamin E (0.30 g/kg DM), and supplemented with vitamin E (0.30 g/kg DM). All experimental diets were formulated according to AFRC (1998). Semen was collected at 14 d intervals from June 17, 2006 to September 2, 2006. Semen characteristics were evaluated. Significant effects (p<0.05) of the week (sampling time) were observed for all parameters except semen volume. Also a significant effect (p<0.05) of dietary treatment was observed for all parameters except for percent sperm with normal morphologies and semen volume. Fish oil supplementation with excess vitamin E had a significant effect (p<0.05) on total number and sperm density, motility and progressive motility, percentage viability and dead sperm. The interaction between fish oil feeding and sampling time was significant (p<0.05) for all of the parameters. The bucks that received fish oil in association with vitamin E, effect fish oil showed the greatest improvement in semen characteristics compared with the other groups (p<0.05). This study showed that fish oil supplementation with vitamin E may have a beneficial effect on the semen quality and fertility of Markhoz bucks.

• Environmental Analysis Health and Toxicology
• /
• v.23 no.2
• /
• pp.129-138
• /
• 2008

The purpose of this study was to investigate the effects of frankincense oil in skin aging animal model. Skin aging was induced by both the irradiation of UVB and the application of squalene monohydroperoxide (Sq-OOH) to the back of experimental animals for 4 weeks. And at the same time experimental materials were applied topically. Six to seven weeks female SHR-1 hairless mice were divided into five groups including normal (N: saline), control (C: UVB+Sq-OOH+saline), vehicle control (VC: UVB+Sq-OOH+jojoba oil), positive control (PC: UVB+Sq-OOH+0.01% retinoic acid) and experimental (E: UVB+Sq-OOH+3% Frankincense oil) groups, five animals each group. Lipid lamella and lipid content in stratum corneum of the E group were almost intact with a regular arrangement which were similar to the N group. Collagen fibers in dermis of the E group were almost intact with a regular arrangement which were similar to the N group. Relatively much less number of mast cells and inflammatory cells were found in the E group compared to the C group. The activities of XO, SOD and CAT were no significant difference between the E and N groups. In conclusion, the application of frankincense oil to the skin aging animal model reduced both the generation of free radicals and the damage of skin tissues. Therefore, frankincense oil can be used practically for the prevention or improvement of skin aging in terms of health promotion and beauty for the people.