Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Inhibition Effects of Frankincense Oil on Skin Aging (II): Focussed on Histological Observation

프랑킨센스 오일의 피부노화 억제 효과 (II) - 조직학적 관찰을 중심으로 -

  • Choi, Oi-Sook (Department of Public Health, Keimyung University) ;
  • Kwon, Mi-Hwa (Department of Public Health, Keimyung University) ;
  • Kong, Min-Kyu (Department of Public Health, Keimyung University) ;
  • Lee, Soon-Hee (Department of Public Health, Keimyung University) ;
  • Gang, Sung-Rye (Department of Skin Care & Obese Theraphy, Kimcheon College) ;
  • Kim, Pil-Sun (Department of Beauty Coordination, Kyung-il University) ;
  • Kim, Young-Chul (Department of Public Health, Keimyung University)
  • 최외숙 (계명대학교 공중보건학과) ;
  • 권미화 (계명대학교 공중보건학과) ;
  • 공민규 (계명대학교 공중보건학과) ;
  • 이순희 (계명대학교 공중보건학과) ;
  • 강성례 (김천대학 피부비만테라피과) ;
  • 김필순 (경일대학교 뷰티코디네이션학과) ;
  • 김영철 (계명대학교 공중보건학과)
  • Published : 2008.06.30
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Abstract

The purpose of this study was to investigate the effects of frankincense oil in skin aging animal model. Skin aging was induced by both the irradiation of UVB and the application of squalene monohydroperoxide (Sq-OOH) to the back of experimental animals for 4 weeks. And at the same time experimental materials were applied topically. Six to seven weeks female SHR-1 hairless mice were divided into five groups including normal (N: saline), control (C: UVB+Sq-OOH+saline), vehicle control (VC: UVB+Sq-OOH+jojoba oil), positive control (PC: UVB+Sq-OOH+0.01% retinoic acid) and experimental (E: UVB+Sq-OOH+3% Frankincense oil) groups, five animals each group. Lipid lamella and lipid content in stratum corneum of the E group were almost intact with a regular arrangement which were similar to the N group. Collagen fibers in dermis of the E group were almost intact with a regular arrangement which were similar to the N group. Relatively much less number of mast cells and inflammatory cells were found in the E group compared to the C group. The activities of XO, SOD and CAT were no significant difference between the E and N groups. In conclusion, the application of frankincense oil to the skin aging animal model reduced both the generation of free radicals and the damage of skin tissues. Therefore, frankincense oil can be used practically for the prevention or improvement of skin aging in terms of health promotion and beauty for the people.

Keywords

References

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