• Solar Energy
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• v.12 no.3
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• pp.10-20
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• 1992

In this experiment, photochemical reaction has been applied to destroy TCE in water phase. The main target of this work is to investigate the technical feasibility of large scale of solar detoxification reactor for water treatment. The results have revealed that solar detoxification utilizing photon energy from the sun is the most attractive process to decompose organic toxins in water phase at room temperature. The detailed results from this work are as follows; (1) The highest conversion ratio of TCE was obtained by using $TiO_2$, annatase as a photocatalyst among $TiO_2$ anatase, $TiO_2$ rutile and $V_2O_5$ under the same experimental condition. The anatase crystal structure was confirmed with XRD analysis, and its surface area was 7.748 $m^2/g$ from the BET-$N_2$ measurement (2) 0.1 wt% of $TiO_2$ anatase has been adopted as optimal quantity for batch slurry reactor at this experimental conditions. (3) The effect of hydrogen peroxide on the conversion of TCE was investigated. Its optimal quantity was 0.06 vol. % under this experimental conditions. (4) The effect of oxygen on the conversion of TCE also was studied by controlling the head space in photoreactor. Results indicated that sufficient amount of oxygen should be supplied to accomplish the highest conversion rate of TCE in water phase.

• Journal of Pharmaceutical Investigation
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• v.36 no.5
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• pp.343-348
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• 2006

The purpose of the present study was to evaluate the bioequivalence of two zolpidem tartrate tablets, Stilnox tablet(Sanofi-aventis Korea, reference product) and Zanilo tablet(ChoDang Pharm Co., Ltd., Korea, test product), according to the guidelines of Korea Food and Drug Administration(KFDA). After adding an internal standard(cimetropium), 250 ${\mu}L$ plasma samples were extracted using 1.3 mL of ethyl acetate. Extracted compounds were analyzed by HPLC with triple-quadrupole mass spectrometry. This method for determination of zolpidem is proved accurate and reproducible with the limit of quantitation of 1 ng/mL in human plasma. Twenty-four healthy male Korean volunteers received each medicine at the zolpidem tartrate dose of 10 mg in a $2{\times}2$ crossover study. There was one-week washout period between the doses. Plasma concentrations of zolpidem were monitored for over a period of 8 hr after the administration. $AUC_{0-t}$(the area under the plasma concentration-time curve) was calculated by the linear trapezoidal rule. $C_{max}$(maximum plasma drug concentration) and $T_{max}$(time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed $AUC_{0-t}$ and $C_{max}$. No significant sequence effect was found for all of the bio-availability parameters indicating that the crossover design was properly performed. The 90% confidence intervals for the log transformed data were acceptable range of log 0.8 to log 1.25(e.g., log 0.92-log 1.06 for $AUC_{0-t}$, log 0.96-log 1.13 for $C_{max}$). The major parameters, $AUC_{0-t}$ and $C_{max}$ met the criteria of KFDA for bioequivalence indicating that Zanilo tablet is bioequivalent to Stilnox tablet.

• Journal of Astronomy and Space Sciences
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• v.29 no.2
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• pp.151-161
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• 2012

An intensive analysis of 148 timings of V700 Cyg was performed, including our new timings and 59 timings calculated from the super wide angle search for planets (SWASP) observations, and the dynamical evidence of the W UMa W subtype binary was examined. It was found that the orbital period of the system has varied over approximately $66^y$ in two complicated cyclical components superposed on a weak upward parabolic path. The orbital period secularly increased at a rate of $+8.7({\pm}3.4){\times}10^{-9}$ day/year, which is one order of magnitude lower than those obtained by previous investigators. The small secular period increase is interpreted as a combination of both angular momentum loss (due to magnetic braking) and mass-transfer from the less massive component to the more massive component. One cyclical component had a $20.^y3$ period with an amplitude of $0.^d0037$, and the other had a $62.^y8$ period with an amplitude of $0.^d0258$. The components had an approximate 1:3 relation between their periods and a 1:7 ratio between their amplitudes. Two plausible mechanisms (i.e., the light-time effects [LTEs] caused by the presence of additional bodies and the Applegate model) were considered as possible explanations for the cyclical components. Based on the LTE interpretation, the minimum masses of 0.29 $M_{\odot}$ for the shorter period and 0.50 $M_{\odot}$ for the longer one were calculated. The total light contributions were within 5%, which was in agreement with the 3% third-light obtained from the light curve synthesis performed by Yang & Dai (2009). The Applegate model parameters show that the root mean square luminosity variations (relative to the luminosities of the eclipsing components) are 3 times smaller than the nominal value (${\Delta}L/L_{p,s}{\approx}0.1$), indicating that the variations are hardly detectable from the light curves. Presently, the LTE interpretation (due to the third and fourth stars) is preferred as the possible cause of the two cycling period changes. A possible evolutionary implication for the V700 Cyg system is discussed.

• Journal of the Korea Concrete Institute
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• v.23 no.1
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• pp.39-48
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• 2011

The present investigation evaluates the flexural behavior of pre-tensioned lightweight concrete beams under two-point symmetrical concentrated loads according to the variation of the partial prestressing ratio and the effective prestress of prestressing strands. The designed compressive strength of the lightweight concrete with a dry density of 1,770 $kg/m^3$ was 35 MPa. The deformed bar with a yield strength of 383 MPa and three-wire mono-strands with tensile strength of 2,040 MPa were used for longitudinal tensile reinforcement and prestressing steel reinforcement, respectively. According to the test results, the flexural capacity of pre-tensioned lightweight concrete beams increased with the increase of the partial prestressing ratio and was marginally influenced by the effective prestress of strands. With the same reinforcing index, the normalized flexural capacity of pre-tensioned lightweight concrete beams was similar to that of pre-tensioned normal-weight concrete beams tested by Harajli and Naaman and Bennett. On the other hand, the displacement ductility ratio of pre-tensioned lightweight concrete beams increased with the decrease of the partial prestressing ratio and with the increase of the effective prestress of strands. The load-displacement relationship of pre-tensioned lightweight concrete beam specimens can be suitably predicted by the developed non-linear two-dimensional analysis procedure. In addition, the flexural cracking moment and flexural capacity of pre-tensioned lightweight concrete beams can be conservatively evaluated using the elasticity theorem and the approach specified in ACI 318-08, respectively.

• Journal of Gastric Cancer
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• v.17 no.4
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• pp.295-305
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• 2017

Purpose: We previously found that the histone methyltransferase suppressor of variegation, enhancer of zeste, trithorax and myeloid-nervy-deformed epidermal autoregulatory factor-1 domain-containing protein 3 (SMYD3) is a potential independent predictive factor or prognostic factor for overall survival in gastric cancer patients, but its roles seem to differ from those in other cancers. Therefore, in this study, the detailed functions of SMYD3 in cell proliferation and migration in gastric cancer were examined. Materials and Methods: SMYD3 was overexpressed or suppressed by transfection with an expression plasmid or siRNA, and a wound healing migration assay and Transwell assay were performed to detect the migration and invasion ability of gastric cancer cells. Additionally, an MTT assay and clonogenic assay were performed to evaluate cell proliferation, and a cell cycle analysis was performed by propidium iodide staining. Furthermore, the expression of genes implicated in the ataxia telangiectasia mutated (ATM) pathway and proteins involved in cell cycle regulation were detected by polymerase chain reaction and western blot analyses. Results: Compared with control cells, gastric cancer cells transfected with si-SMYD3 showed lower migration and invasion abilities (P<0.05), and the absence of SMYD3 halted cells in G2/M phase and activated the ATM pathway. Furthermore, the opposite patterns were observed when SMYD3 was elevated in normal gastric cells. Conclusions: To the best of our knowledge, this study provides the first evidence that the absence of SMYD3 could inhibit the migration, invasion, and proliferation of gastric cancer cells and halt cells in G2/M phase via the ATM-CHK2/p53-Cdc25C pathway. These findings indicated that SMYD3 plays crucial roles in the proliferation, migration, and invasion of gastric cancer cells and may be a useful therapeutic target in human gastric carcinomas.

• Journal of The Korean Association For Science Education
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• v.31 no.6
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• pp.942-957
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• 2011

The purpose of this research was to examine the concept of elementary school teachers of combustion. The participants were selected from the elementary school teachers who had various career experiences, 6th grade science teaching experiences, and academic backgrounds on science. For the purpose of this study, 12 elementary school teachers took the concept-test formed five questions on combustion and were interviewed. The concept-test was composed with 'The definition of combustion', 'The reason that the candle was blown out when glass was closed.', 'The existence of oxygen and carbon dioxide of before and after combustion in glass', 'Combustion of iron', 'Combustion products'. And the collected data by semi-structured interviews based on responses to the concept-test. During the analysis of the data, additional interviews by phone, e-mail and Internet messenger were conducted if necessary. The answers to each question were classified into three levels: (Scientific-concept(S), Partial-concept(P), Misconcept(M)). The research results showed that all teachers had misconceptions or partial-concept of more than 50 percent of each question. Teachers who had the 6th grade science teaching experience acquired scientific concepts of the combustion more than teachers who did not have the 6th grade science teaching experience. We should develop visualization materials about the change of gases during combustion and use these materials for implementation of the scientific concept.

• Journal of the Korean Institute of Landscape Architecture
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• v.38 no.3
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• pp.107-114
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• 2010

This study was undertaken to suggest a Pinus densiflora community planting model in the central cool temperate zone of Korea and nearby areas. For the purpose of this study, we surveyed various DBH classes of the P. densiflora community in Dangjin-gun, Choongchungnam-do. We surveyed the size of entire individuals in the 92 plots as well as surveyed the location of individuals in each tree layer and sub-tree layer(1/100 scale) of 44 plots using a quadrant method from young to old communities. As a result of analysis, the tree layer was growing well but the basal areas of the subtree layer were less than 10% compared with the tree-layer. This indicates the subtree layer is not in general growing well in the P. densiflora community. There were no significant patterns in the shrub layer. A P. densiflora community planting would consist of a tree layer and a shrub layer and the finding of growth patterns of the tree layer is significant. In order to make a model of the shrub layer, an additionally survey of another shrub layer is needed in a nearby planting area. Both regression models, 1) between tree layer DBHs and individuals per unit area, and 2) between individuals per unit area and shortest distances of individuals, can yield much information through study.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.3
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• pp.336-344
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• 2011

The purpose of this study is to analyze the radiation-pattern characteristics above 1 GHz for the electromagnetic wave radiated from multi-slot such as ventilations, etc. on the enclosure of an EUT and so to make recommendations for suitable test methods. An experimental EUT was formed by putting a comb-generator at the center of a rectangular enclosure with 4 slots, and its radiation pattern was analyzed in the frequency range of 1~6 GHz. As analysis results, multi-lobe appears above 2 GHz and the number of multi-lobes is growing as the frequency increases. And real radiated-emission measurements were performed for the experimental EUT by scanning a receiving antenna in the height of 1~4 m and tilting toward maximum radiation, as well as setting the height of a receiving antenna to the central position of the EUT which is prescribed at the present standards. The measured results are +12.8 dB in the scanning and +16.4 in the scanning and tilting compared with the present standard test method. Therefore, the latter must be revised in order to consider the radiation pattern above 1 GHz.

• Journal of the Korean GEO-environmental Society
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• v.14 no.10
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• pp.49-57
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• 2013

Recently, recycling of the industrial by-products has been an important issue of the Yeosu bay, where large industrial complex is located. Major industrial by-products which are produced from Yeosu industrial complex area are phosphogypsum and flyash, which are about 82% and 10% of the 1.6 million tons industrial by-products. Moreover since the Yeosu industrial complex is located at seaside, phosphogypsum has been pointed as cause of serious environmental contaminant from the regional society. Therefore recycling study can't be delayed anymore. In this paper, artificial aggregate was manufactured by non-sintering process from industrial byproducts - e.g., phosphogypsum and slag - as a geotechnical drainage material. To show the feasibility of the artificial aggregate as a geotechnical drainage material, geotechnical experiments including particle size analysis, permeability test, and large scale direct shear test were carried out. Test results show that the permeability of the artificial aggregates range from $6.94{\times}10^{-1}cm/sec$ to $8.86{\times}10^{-1}cm/sec$, which is much larger value than those are required for the drainage material from the construction specification in Korea, and the friction angle of the artificial aggregate is as large as that of sand in water immersion conditions. From the test results, it was concluded that artificial aggregate made from industrial by-products can be used successfully as a geotechnical drainage material.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.22 no.12
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• pp.2674-2685
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• 1997

In this paper, the design and imprlementation of dual-band power amplifier which is used as a critical part for mobile phone to be simultaneously working at a dual band, 800MHz CDAM and PCS frequency band is described. DC operating point of power FET is limited to Class-B to enable long talk time considering that the tyupical power range of CDMA phones in working is around 10 to Class-B to enable long talk time considering that the typical power range of CDMA phones in working is around 10 to 15dBm, i.e., liner range. The power amplifier which employs two GaAs FETs with good linerity at a low operating point has duplexer cuplexer circuit to separate two frequency bands at input and output stage. Electromagnetic analysis for via holes and coupling between narrow transmission lines is included to design a circuit. Moduld size of 0.96CC($22{\times}14.5{\times}3mm^3$) and maximum module current of 130mA at output power range, 10 to 15dBm are attained. The power amplifer module has achieved ACPR performance with 2 to 3dB marging from IS-95 requirement at output powers, 23.5dBm for PCS and 28dBm for 800MHz CDMA respectively.