• 대한한의학방제학회지
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• 제21권2호
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• pp.165-172
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• 2013

Objectives : This experiment was performed in order to study the effect of Maekmundong-tang on dyspnea patients. Methods : This study involved 14 dyspnea patients from March 1, 2012 to May 31, 2012. Lung capacity of the patients is evaluated with Peak flow meter. Results : Maekmundong-tang administration was revealed effect on dyspnea patients' lung capacity. Conclusions : It was found that Maekmundong-tang administration was effective on dyspnea patients' lung capacity. The mean degree of improvement was 21.79(L/min). It was shown that the more mild dyspnea level was, the more effective and short-term administration more effective.

• Tuberculosis and Respiratory Diseases
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• 제60권4호
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• pp.397-403
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• 2006

연구배경: 만성폐쇄성폐질환은 질병의 중증도를 추정 정상치에 대한 $FEV_1$의 백분율을 기준으로 분류해 왔다. 그러나, 같은 폐기능 검사소견을 보이는 환자들 사이에서도 환자가 느끼는 주관적 호흡곤란에는 차이가 있다. 본 연구에서는 호흡곤란이 $FEV_1$를 비롯하여, 건강관련 삶의 질, 주변으로부터 받는 도움의 정도, 직업 등에 영향을 받는지에 대해 알아보고자 하였다. 방법: 2002년 6월부터 2004년 5월까지 경북대학교병원 호흡기 내과에서 만성폐쇄성폐질환으로 추적관찰 중이며, 임상적으로 안정되어 있고 비가역적인 폐쇄성 폐기능 장애를 가진 환자 36명을 대상으로 하였다. 만성 폐쇄성 폐질환의 병기는, GOLD 병기를 따랐으며, 호흡곤란 척도는 MRC 호흡곤란 척도를 사용하였다. 건강 관련 삶의 질은 한국어 St. Goerge's respiratory questionnaire(SGRQ)를 사용하였다. 결과: 환자들의 평균 $FEV_1$은 추정 정상치의 32.0%였다. GOLD 병기와 호흡곤란 정도사이에 유의한 상관관계는 없었다(p=0.114). 호흡곤란이 심할수록 SGRQ 값의 증상(symptom)(p=0.041), 활동력(activity)(p=0.004), 영향력(impact)(p=0.001), 총점(total)(p<0.001) 수치 모두에서 의미있게 높은 수치를 보였다. 호흡곤란 정도와 직업간에 의미있는 상관관계는 없었으며(p=0.259), 호흡곤란이 심할수록 환자가 주변으로부터 받는 도움 정도는 적다고 느끼는 상관관계가 뚜렷하였다(p=0.011). 결론: 만성폐쇄성폐질환자의 진료에서 환자가 느끼는 주관적인 호흡곤란은 $FEV_1$에 따른 병기 외에도 건강관련 삶의 질 및 주변의 지지 정도와 더 연관성을 가질 수 있다는 점이 고려되어야 할 것으로 사료된다.

• 한국인공지능학회지
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• 제6권2호
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• pp.17-22
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• 2018

According to the World Health Organization, the top 10 causes of death worldwide include heart disease. Heart diseases include coronary disease, which induces acute myocardial infarction. Ticagrelor drugs are being used to treat acute alliances, but it has become difficult to breathe due to the drugs. In a related study, Tobias predicted that uric acid causes acute respiratory distress independently of other factors, including BNP. And in the Ahmad study, serum uric acid numbers were related to the left ventricle depending on the level of uric acid. Experimental data are data used after 155 patients who received coronary intervention took ticagrelor. The research methods were leveraged by gradient decent algorithm and linear regression. In order to avoid overfitting in the experiment, training data and test data were separated into 70 and 30 percent respectively. The experimental results lacked the predictability of other attributes except DT in the correlation coefficient and crystal coefficient. However, all attributes related to dyspnea other than DT are determined to be related to causing relaxation of the heart in the left ventricle. Therefore, the attribute causing dyspnea is determined to be an attribute causing relaxation of the heart of the DT and left ventricle.

• The Korean Journal of Pain
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• 제4권1호
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• pp.42-46
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• 1991

Splanchnic nerve block with neurolytics has been used to control the upper abdominal cancer pain. This gastric cancer case with severe chronic obstructive pulmonary disease complained of upper abdominal pain, severe dyspnea and orthopnea. He maintained a sitting position most of the time with nasal oxygen inhalation because he could not remain in a supine or prone position. We performed the unilateral splanchnic nerve alcohol block under right lateral position at the T12 and L1 vertebral level. For a short time after the block, he required oxygen inhalation therapy. Three months after unilateral alcohol block, he is still alive without severe abdominal pain and severe dyspnea.

• Journal of Gastric Cancer
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• 제17권4호
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• pp.342-353
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• 2017

Purpose: This study evaluated the changes in nutritional status based on quality of life (QoL) item-level analysis to determine whether individual QoL responses might facilitate personal clinical impact. Materials and Methods: This study retrospectively evaluated QoL data obtained by the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Core 30 (QLQ-C30) and Quality of Life Questionnaire-Stomach (QLQ-STO22) as well as metabolic-nutritional data obtained by bioelectrical impedance analysis and blood tests. Patients were assessed preoperatively and at the 5-year follow-up. QoL was analyzed at the level of the constituent items. The patients were categorized into vulnerable and non-vulnerable QoL groups for each scale based on their responses to the QoL items and changes in the metabolic-nutritional indices were compared. Results: Multiple shortcomings in the metabolic-nutritional indices were observed in the vulnerable groups for nausea/vomiting (waist-hip ratio, degree of obesity), dyspnea (hemoglobin, iron), constipation (body fat mass, percent body fat), dysphagia (body fat mass, percent body fat), reflux (body weight, hemoglobin), dry mouth (percent body fat, waist-hip ratio), and taste (body weight, total body water, soft lean mass, body fat mass). The shortcomings in a single index were observed in the vulnerable groups for emotional functioning and pain (EORTC QLQ-C30) and for eating restrictions (EORTC QLQ-STO22). Conclusions: Long-term postoperative QoL deterioration in emotional functioning, nausea/vomiting, pain, dyspnea, constipation, dysphagia, reflux, eating restrictions, dry mouth, and taste were associated with nutritional shortcomings. QoL item-level analysis, instead of scale-level analysis, may help to facilitate personalized treatment for individual QoL respondents.

• 대한임상독성학회지
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• 제3권1호
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• pp.40-44
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• 2005

Nitrogen dioxide ($NO_2$), which produced during the process of silage, metal etching, explosives, rocket fuels, welding, and by-product of burning of fossil fuels, is one of major components of air pollutant. Accidental exposure of high level of $NO_2$ produces cough, dyspnea, pulmonary edema which may be delayed $4\~12$ hours and, in $2\~6$weeks, bronchiolitis obliterans. We experienced a case of acute pulmonary injuny induced by industrial exposure to high level of $NO_2$ during repair of $NO_2$ pipeline in a refinery. A 55-year-old man experienced nausea and severe dyspnea in 6 hours after $NO_2$ inhalation. Initial blood gas examination revealed severe hypoxemia accompanying increased alveolar-arterial O2 difference. Radiological examination showed diffuse ground glass opacities in both lung fields. Clinical symptoms and laboratory findings, including radiological study and pulmonary function test were improved with conservative treatment using inhaled oxygen and bronchodilator. and there was no evidence of bronchial fibrosis and bronchiolitis obliterance in chest high resolution computed tomography performed 6 weeks after exposure. Here, we report a case of $NO_2$ induced acute pulmonary injuny with a brief review of the relevant literature.

• 대한한방내과학회지
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• 제42권3호
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• pp.403-411
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• 2021

Background: This case report shows the effect of Hyulbuchuko-tang on a patient with a contraindication to anticoagulants who complained about dyspnea caused by pulmonary embolism (PE). Case report: A PE patient with dyspnea was treated with herbal medication, Hyulbuchuko-tang, for 28 days. Evaluations took place by assessing time for oxygen application time per day, follow-up chest CT, and D-dimer test results. Oxygen application time per day decreased, and oxygen therapy ended on the 14th day of Hyulbuchuko-tang treatment. Follow-up chest CT showed resolution of PE. The D-dimer level decreased on the 24th day and decreased more after 1 month later. Conclusion: This clinical case study suggests that Hyulbuchuko-tang might be effective in the resolution of PE and can be an option as a treatment for PE patients with contraindications to anticoagulants.

• 대한한의학회지
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• 제42권2호
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• pp.98-106
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• 2021

본 증례보고에서는 과로 후 공황장애가 온 44세 남성 환자를 상한론 변병진단체계(傷寒論 辨病診斷體系)에 입각하여 태양병(太陽病)으로 진단하고 15조문의 계지탕(桂枝湯)을 약 6개월 동안 투여한 결과 주소증인 심계항진, 가슴답답함, 기역(氣逆), 호흡곤란을 포함한 제반 증상들이 호전되는 치료적 효과를 확인할 수 있었다.

• 대한간호학회지
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• 제36권5호
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• pp.853-862
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• 2006

Purpose: The purpose of this study was to identify the factors that influence the functional status of patients with heart failure. Method: A descriptive, correlational study design was used. The participants in this study were 260 patients with heart failure who were admitted at Y University and U University in Seoul, Korea. Between September 2005 and December 2005 data was collected by an interview using a questionnaire and from medical records. The Functional status was measured with KASI. Physical factors (dyspnea, ankle edema, chest pain, fatigue, and sleep dysfunction), psychological factors (anxiety and depression), and situational factors (self-management compliance and family support) were examined. Result: In general, the functional status, anxiety, depression, self-management compliance, and family support was relatively not good. The level of fatigue was highest and the level of ankle edema was lowest for physical symptom experiences. In regression analysis, functional status was significantly influenced by dyspnea(23%), age(13%), monthly income(7%), fatigue(3%), ankle edema(2%), depression(1%), and length of stay in the hospital(1%). These factors explained 50% of the variables in the functional status. Conclusion: These results suggest that psycho-physiological symptoms management should be a focus to improve the functional status in patients with heart failure.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3129-3133
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• 2012

Diagnosis and treatment procedures in cancers and resulting anxiety negatively affect the individual and the family. Particularly treatment methods may generate psychological symptoms. The aim of this study was to determine the level of such symptoms in Turkish gynecologic cancer patients receiving chemotherapy. A total of 41 patients who were referred to our gynecologic oncology research clinic between January-March 2012, receiving 3 months or more chemotherapy and who agreed to participate were enrolled in study. All the data were collected using a personal information form, Edmonton Symptom Assesment System and State-Trait Anxiety Inventory. Patients received highest point average from fatigue symptom ($6.53{\pm}2.67$) and lowest point average from dyspnea ($1.53{\pm}3.03$) according to Edmonton Symptom Assesment System. The mean State Anxiety score of patients was $43.1{\pm}9.77$ and mean Trait Anxiety score was $46.7{\pm}7.01$. Comparing symptoms of patients and mean State Anxiety score it was found that there was a statistically significant corelation with symptoms like pain (p<0.05), sadness (p<0.001), insomnia (p<0.05), state of well being (p<0.001) and dyspnea (p<0.05). Similarly comparing symptoms of patients and mean Trait Anxiety score demonstrated significant correlations for fatigue (p<0.05), sadness (p<0.01), insomnia (p<0.01) and state of well-being (p<0.01). As a result, patients with gynecological cancers experienced symptoms related to chemotherapy and a moderate level of anxiety. In accordance, appropriate interventions should recommended for the evaluation and improvement of anxiety and symptoms related to treatment in cancer patients.