• Korean Journal of Biological Psychiatry
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• v.19 no.1
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• pp.17-28
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• 2012

The primary purpose of this review is to present an overview of relationship between human spontaneous eyeblinking and internal cognitive processes. The second purpose is to address the neural substrates of human eyeblinking based on recent studies focusing on the central dopaminergic system and to explore the significance of spontaneous eyeblinks in neuropsychiatric disorders. We reviewed recent and previous studies on eyeblink patterns under various cognitive tasks. We also reviewed neural substrates of eyeblinking, particularly based on the central dopaminergic system. This paper suggests that spontaneous eyeblinks are highly correlated with various cognitive processes and the activity of central dopaminergic system. Various neuropsychiatric disorders are related to the alteration of the occurrence of eyeblinking. Spontaneous eyeblinking is the unique human behavior that occurs regularly without conscious effort. It is known that the rate of eyeblinking is modulated by internal cognitive processes and dopamine-related neuropsychiatric disorders. Further research is required to how the temporal dynamics of spontaneous eyeblinking is correlated with the disease activity and progression.

• Ocean Systems Engineering
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• v.8 no.3
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• pp.247-279
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• 2018

This study aims to investigate the behavioral characteristics of the LWSCR (lazy-wave steel catenary riser) for a turret-moored FPSO (Floating Production Storage Offloading) by using fully-coupled hull-mooring-riser dynamic simulation program in time domain. In particular, the effects of initial geometric profile on the global performance and structural behavior are investigated in depth to have an insight for optimal design. In this regard, a systematic parametric study with varying the initial curvature of sag and arch bend and initial position of touch down point (TDP) is conducted for 100-yr wind-wave-current (WWC) hurricane condition. The FPSO motions, riser dynamics, constituent structural stress results, accumulated fatigue damage of the LWSCR are presented and analyzed to draw a general trend of the relationship between the LWSCR geometric parameters and the resulting dynamic/structural performance. According to this study, the initial curvature of the sag and arch bend plays an important role in absorbing transferred platform motions, while the position of TDP mainly affects the change of static-stress level.

• Advances in Computational Design
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• v.5 no.2
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• pp.111-125
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• 2020

The flow behavior of polymer melts within a slit die is an important consideration when designing a die geometry. The quality of the extruded polymer product can be determined through an evaluation of the flow homogeneity, wall shear rate and pressure drop across the central height of the die. However, mathematical formulations cannot fully determine the behavior of the flow due to the complex nature of fluid dynamics and the nonlinear physical properties of the polymer melts. This paper examines two slit die geometries in terms of outlet velocity uniformity, shear rate uniformity at the walls and pressure drop by using the licensed computational fluid dynamics package, Ansys POLYFLOW, based on the finite element method. The Carreau-Yasuda viscosity model was used for the rheological properties of the polypropylene. Comparative analysis of the simulation results will conclude that the modified die design performs better in all three aspects providing uniform exit velocity, uniform wall shear rates, and lower pressure drop.

• BMB Reports
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• v.53 no.7
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• pp.357-366
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• 2020

Currently, most biological research relies on conventional experimental techniques that allow only static analyses at certain time points in vitro or ex vivo. However, if one could visualize cellular dynamics in living organisms, that would provide a unique opportunity to study key biological phenomena in vivo. Intravital microscopy (IVM) encompasses diverse optical systems for direct viewing of objects, including biological structures and individual cells in live animals. With the current development of devices and techniques, IVM addresses important questions in various fields of biological and biomedical sciences. In this mini-review, we provide a general introduction to IVM and examples of recent applications in the field of immunology, oncology, and vascular biology. We also introduce an advanced type of IVM, dubbed real-time IVM, equipped with video-rate resonant scanning. Since the realt-ime IVM can render cellular dynamics with high temporal resolution in vivo, it allows visualization and analysis of rapid biological processes.

• Journal of Biomedical Engineering Research
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• v.13 no.2
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• pp.165-174
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• 1992

Compliance mismatch across an end-to-end anastomosis was measured In the In vitro experimental setup. A 35mm camera was used and Image process was done in Gould/ DeAnza Image processor. The results showed that compliances of Penrose tubing and synthetic PTFE grafts were In good agreement with the previously reported In vivo data. PTFE grafts exhibited a nonlinear behavior with compliance decreasing with Increasing transmural pressure, whereas the compliance of the Penrose tubing remained relatively constant within the range of the pressures in which data were obtained. The lumen cross sections at the anastomosis were affected by the suture and the mismatch In compliance between the Penrose tubing and vascular grafts. The varla~lons In the lumen dtameter at the anastomosis was more pronounced with increasing transmural pressures. From the present study, it was clearly demonstrated that the compliance of prosthetic grafts Is much lower than that of the arteries. In addition to the hemodynamlc consequences, compliance mismatch across the anastomosis has been known to lead to Increased anastomotlc and suture stresses with resultant suture line dehlscence and false aneurysm formation. Thus, there are good hemodynamic reasons to suppose that Introduction of a less compliant arterial graft Into the arterial circulation wlll be damaging and that grafts should be made to match the elastic behavior of their host arteries as closely possible.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.5
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• pp.84-89
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• 2001

The alignment of the rollers carrying the web is found to be one of important factors to the lateral behavior of the moving web and to the quality of the final web products. But, the perfect alignment of the rollers is not always possible and the web itself can be cambered. Thus the control of lateral behavior of the moving web is critical in the most of web handling systems. The web guiding system that adjusts the angle of the alignment between two adjacent rollers is commonly used in industry. But, in this paper a new web guiding system is proposed by using the lateral dynamics of the moving web induced by a tilted roller in normal direction of a web. The computer simulation study was carried out to verify the steering performance of the suggested guiding system. Computer simulation study shows that the performance of the new guiding mechanism is better than that of an existing guiding mechanism.

• Journal of Korean Society of Water and Wastewater
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• v.27 no.2
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• pp.215-222
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• 2013

The fluctuation of inlet flow to a water treatment plant makes a serious problem that it can change the outlet flowrate from each process abruptly. Since it takes very short time for the surface wave occurred from the fluctuation of inlet flow to reach the latter processes, it is impossible for operators to cope with that stably. In order to investigate the characteristics of hydraulic behavior for rectangular sedimentation basin in water treatment plant, CFD(Computational Fluid Dynamics) simulation were employed. From the results of both CFD simulations, it was confirmed that time taken for the follow-up processes by the fluctuation in intake well can be estimated by the propagation velocity of surface waves. Also, it takes very short time for the surface wave occurred from the fluctuation of inlet flow to reach the latter processes. In the case of inlet flowerate being increased sharply, local velocity within sedimentation basin appeared as wave pattern and increased due to convection current. Also, it could be observed that vortex made local velocity in the vicinity of bottom rise.

• Geomechanics and Engineering
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• v.14 no.4
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• pp.355-366
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• 2018

One of the significant problems in the design of onshore pipelines in seismic areas is their stability in case of liquefaction. Several model tests and numerical analyses allow investigating the behavior of pipelines when the phenomenon of liquefaction occurs. While experimental tests contribute significantly toward understanding the liquefaction mechanism, they are costly to perform compared to numerical analyses; on the other hand, numerical analyses are difficult to execute, because of the complexity of the soil behavior in case of liquefaction. This paper reports an overview of the existing computational methods to evaluate the stability of onshore pipelines in liquefied soils, with particular attention to the development of excess pore water pressures and the floatation of buried structures. The review includes the illustration of the mechanism of floating and the description of the available calculation methods that are classified in static and dynamic approaches. We also highlighted recent trends in numerical analyses. Moreover, for the static condition, referring to the American Petroleum Institute (API) Specification, we computed and compared the uplift safety factors in different cases that might have a relevant practical use.

• Journal of Haehwa Medicine
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• v.10 no.1
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• pp.365-374
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• 2001

The brain is one of the most complex systems in nature. Brain waves, or the "EEG", are electrical signals that can be recorded from the brain, either directly or through the scalp. The kind of brain wave recorded depends on the behavior of the animal, and is the visible evidence of the kind of neuronal (brain cell) processing necessary for that behavior. But, EEG had been considered as a virtually infinite-dimensional random signal. However, nonlinear dynamics light on dynamical aspects of the human EEG. The methods of nonlinear dynamics provide excellent tolls for the study of multi-variable, complex system such as EEG. In this study, 20 persons seperated in 2 groups were examined with EEG, one group stimulated on specific area of the sole of the foot with footbed inside the shoes. This experiment resulted in at the group stimulated on specific area of the sole of the foot correlation dimension of P4 and O1 channels increased significantly. Therefore. we obserbed that stimulation on specific area of the body had a constant effections on the specific channels.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.3
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• pp.68-74
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• 2006

The evaluation of durability performance in Virtual Testing Laboratory(VTL) is a new concept of vehicle design, which can reduce the automotive design period and cost. In this study, the multibody dynamics model of a car is built with a reverse engineering design. Hard points and masses of components are measured by a surface scanning device and imported into CAD system. In order to simulate the non-linear dynamic behavior of force elements such as dampers and bushes, components and materials are tested with specialized test equipments. An optimized numerical model for the damping behavior is used and the hysteresis of bush rubber is considered in the simulation. Loads of components are calculated in VTL and used in the evaluation of durability performance. In order to verify simulation results, loads of components in the vehicle are measured and durability tests are performed.