• Journal of the Optical Society of Korea
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• 제20권6호
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• pp.762-769
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• 2016

The dynamic modulation transfer function (MTF) for image degradation caused by sinusoidal vibration is formulated based on a Bessel function of the first kind. The presented method makes it possible to obtain an analytical MTF expression derived for arbitrary frequency sinusoidal vibration. The error obtained by the use of finite order sum approximations instead of infinite sums is investigated in detail. Dynamic MTF exhibits a stronger random behavior for low frequency vibration than high frequency vibration. The calculated MTFs agree well with the measured MTFs with the slant edge method in imaging experiments. With the proposed formula, allowable amplitudes of any frequency vibration are easily calculated. This is practical for the analysis and design of the line-of-sight stabilization system in the remote sensing camera.

• 전자공학회논문지
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• 제52권1호
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• pp.111-120
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• 2015

HDR(high dynamic range) 영상 생성은 실세계의 고명암비 영상을 재현하는 방법이다. Exposure fusion은 여러 HDR 영상 생성방법 중 한 가지로 true-HDR 영상을 생성하지 않고, 바로 pseudo-HDR 영상을 생성하는 방법이다. 그러나 노출이 다른 여러 입력영상들 중에서 이동하는 물체가 존재하면 잔상 효과가 발생하여 pseudo-HDR 영상의 화질 열화를 가져온다. 이러한 단점을 해결하기 위해 본 논문에서는 시간 영역에서 일치성 평가를 통한 무 잔상 exposure fusion을 제안하였다. 먼저 다중 역치 및 밝기를 이용한 비트맵과 색도 일관성 맵을 이용하여 각 입력 영상들간의 일치성을 평가하였고, 이를 시간 영역 가중치 맵으로 나타내었다. 그리고 기존 exposure fusion에서의 공간 영역 가중치 맵과 결합하여 최종 가중치 맵을 생성하였다. 마지막으로 각각 입력 영상에 최종 가중치 맵을 적용한 후, 합성하여 잔상이 제거된 pseudo-HDR 영상을 생성하였다. 실험을 통해 제안된 방법의 pseudo-HDR이 기존의 방법보다 잔상이 더 많이 제거되어 화질이 개선됨을 확인하였고, 객관적인 평가 방법인 기준 영상 대비 오차도 더 적게 나타남을 확인하였다.

• Korean Journal of Radiology
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• 제21권1호
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• pp.58-67
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• 2020

Objective: Third-generation dual-source computed tomography (3rd-DSCT) allows dynamic myocardial CT perfusion imaging (dynamic CTP) with a 10.5-cm z-axis coverage. Although the increased radiation exposure associated with the 50% wider scan range compared to second-generation DSCT (2nd-DSCT) may be suppressed by using a tube voltage of 70 kV, it remains unclear whether image quality and the ability to quantify myocardial blood flow (MBF) can be maintained under these conditions. This study aimed to compare the image quality, estimated MBF, and radiation dose of dynamic CTP between 2ndDSCT and 3rd-DSCT and to evaluate whether a 10.5-cm coverage is suitable for dynamic CTP. Materials and Methods: We retrospectively analyzed 107 patients who underwent dynamic CTP using 2nd-DSCT at 80 kV (n = 54) or 3rd-DSCT at 70 kV (n = 53). Image quality, estimated MBF, radiation dose, and coverage of left ventricular (LV) myocardium were compared. Results: No significant differences were observed between 3rd-DSCT and 2nd-DSCT in contrast-to-noise ratio (37.4 ± 11.4 vs. 35.5 ± 11.2, p = 0.396). Effective radiation dose was lower with 3rd-DSCT (3.97 ± 0.92 mSv with a conversion factor of 0.017 mSv/mGy∙cm) compared to 2nd-DSCT (5.49 ± 1.36 mSv, p < 0.001). Incomplete coverage was more frequent with 2nd-DSCT than with 3rd-DSCT (1.9% [1/53] vs. 56% [30/54], p < 0.001). In propensity score-matched cohorts, MBF was comparable between 3rd-DSCT and 2nd-DSCT in non-ischemic (146.2 ± 26.5 vs. 157.5 ± 34.9 mL/min/100 g, p = 0.137) as well as ischemic myocardium (92.7 ± 21.1 vs. 90.9 ± 29.7 mL/min/100 g, p = 0.876). Conclusion: The radiation increase inherent to the widened z-axis coverage in 3rd-DSCT can be balanced by using a tube voltage of 70 kV without compromising image quality or MBF quantification. In dynamic CTP, a z-axis coverage of 10.5 cm is sufficient to achieve complete coverage of the LV myocardium in most patients.

• The Journal of the Acoustical Society of Korea
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• 제15권2E호
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• pp.76-84
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• 1996

The experimental testing results of the large-scale version of a forward-looking ultrasound imaging catheter(FLUIC) are presented, along with the fabrication techniques used, experimental methods, and comparisons of the measured and simulated results. The transducer model is verified by measuring the electrical impedance of the transducer. The pulse width, beamwidth, and the dynamic range for both transmit and pulse-echo response of the fabricated FLUIC are also analyzed. The experimental results conformed its forward-looking imaging capability and the sources of discrepancies between the simulated and experimental beam profiles are addressed.

• Journal of Yeungnam Medical Science
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• 제12권1호
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• pp.141-148
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• 1995

본 교실에서는 측두하악관절주위의 동통, 관절 잡음동의 증상을 주소로 내원한 환자들에 있어서 역동적 자기공명영상의 촬영을 시행하여 관절원판의 전방변위와 형태적 이상 및 주위 구조물들과의 관계를 분석한 결과 근육성 동통기능장애와의 감별뿐만 아니라 환자의 중상에 따른 관절 내부 장애의 정도를 파악할 수 있었으며 악기능시의 구조적 이상, 장애의 원인 등을 판독하여 치료의 방침을 세우는데 있어 매우 유용한 정보를 얻을 수 있었기에 보고 하는 바이다.

• 방송공학회논문지
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• 제23권3호
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• pp.369-382
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• 2018

본 논문은 딥 컨볼루션 뉴럴 네트워크(CNN)를 이용하여 행 별로 서로 다른 노출로 촬영된 단일 영상을 HDR 영상으로 변환하는 기법을 제안한다. 제안하는 알고리즘은 먼저 입력 영상에서 저조도 또는 포화로 인해 발생하는 정보 손실 영역을 CNN을 이용하여 복원하여 휘도맵을 생성한다. 또한, CNN 학습 과정에서 인간의 시각 인지 특성을 고려할 수 있는 손실 함수를 제안한다. 마지막으로 복원된 휘도맵에 디모자이킹 필터를 적용하여 최종 HDR 영상을 획득한다. 컴퓨터 모의실험을 통해 제안하는 알고리즘이 기존의 기법에 비해서 높은 품질의 HDR 영상을 취득하는 것을 확인한다.

• 반도체디스플레이기술학회지
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• 제16권3호
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• pp.82-86
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• 2017

High dynamic range (HDR) imaging offers a radically approach of representing colors in digital images. Instead of using the range of colors produced by given devices, HDR imaging method manipulates and stores all colors and brightness levels visible to the human eye. To faithfully represent, store and then reproduce all these effects, the original scene must be stored and treated using high fidelity HDR techniques. Then, tone mapping is required to accommodate HDR image to low dynamic range (LDR) devices, and tone mapping operation of HDR image for realistic display is commonly researched. However, color visualization for analyzing scene luminance in HDR imaging has less attention from researches. This paper presents and implements a method for reproduction and visualization of the false color in HDR images. We produce a color visualization framework with several mapping functions, and evaluate their effectiveness by using RMAE and SNR with commonly used HDR image data. Experiment reveals that the sigmodal mapping function shows better performance in the false color visualization, compared to other methods.

• Korean Journal of Radiology
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• 제25권5호
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• pp.459-472
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• 2024

Hyperpolarized (HP) carbon-13 (¹³C) MRI represents an innovative approach for noninvasive, real-time assessment of dynamic metabolic flux, with potential integration into routine clinical MRI. The use of [1-¹³C]pyruvate as a probe and its conversion to [1-¹³C]lactate constitute an extensively explored metabolic pathway. This review comprehensively outlines the establishment of HP ¹³C-MRI, covering multidisciplinary team collaboration, hardware prerequisites, probe preparation, hyperpolarization techniques, imaging acquisition, and data analysis. This article discusses the clinical applications of HP ¹³C-MRI across various anatomical domains, including the brain, heart, skeletal muscle, breast, liver, kidney, pancreas, and prostate. Each section highlights the specific applications and findings pertinent to these regions, emphasizing the potential versatility of HP ¹³C-MRI in diverse clinical contexts. This review serves as a comprehensive update, bridging technical aspects with clinical applications and offering insights into the ongoing advancements in HP ¹³C-MRI.

• 대한방사성의약품학회지
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• 제1권2호
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• pp.123-129
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• 2015

$^{64}Cu$-labeled diacetyl-bis($N^4$-methylthiosemicarbazone) is a promising agent for internal radiation therapy and imaging of hypoxic tissues. In the study, we confirmed hypoxia regions in VX2 tumor implanted rabbits with injection $^{64}Cu$-ATSM and $^{18}F$-FDG using positron emission tomography (PET)/computed tomography (CT). PET images with $^{18}F$-FDG and $^{64}Cu$-ATSM were obtained for 40 min by dynamic scan and additional delayed PET images of $^{64}Cu$-ATSM the acquired up to 48 hours. Correlation between intratumoral $O_2$ level and $^{64}Cu$-ATSM PET image was analyzed. $^{64}Cu$-ATSM and $^{18}F$-FDG were intravenously co-injected and the tumor was dissected and cut into slices for a dual-tracer autoradiographic analysis. In the PET imaging, $^{64}Cu$-ATSM in VX2 tumors displayed a specific uptake in hypoxic region for48 h. The uptake pattern of $^{64}Cu$-ATSM in VX2 tumor at 24 and 48 h did not match to the $^{18}F$-FDG. Through ROI analysis, in the early phase (dynamic scan), $^{18}F$-FDG has positive correlation with $^{64}Cu$-ATSM but late phase (24 and 48 h) of the $^{64}Cu$-ATSM showed negative correlation with $^{18}F$-FDG. High uptake of $^{64}Cu$-ATSM in hypoxic region was responded with significant decrease of oxygen pressure, which confirmed by $^{64}Cu$-ATSM PET imaging and autoradiographic analysis. In conclusion, $^{64}Cu$-ATSM can utilize for specific targeting of hypoxic region in tumor, and discrimination between necrotic- and viable hypoxic tissue.

• Nuclear Engineering and Technology
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• 제38권4호
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• pp.327-342
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• 2006

Radiation therapy is an important part of cancer treatment in which cancer patients are treated using high-energy radiation such as x-rays, gamma rays, electrons, protons, and neutrons. Currently, about half of all cancer patients receive radiation treatment during their whole cancer care process. The goal of radiation therapy is to deliver the necessary radiation dose to cancer cells while minimizing dose to surrounding normal tissues. Success of radiation therapy highly relies on how accurately 1) identifies the target and 2) aim radiation beam to the target. Both tasks are strongly dependent of imaging technology and many imaging modalities have been applied for radiation therapy such as CT (Computed Tomography), MRI (Magnetic Resonant Image), and PET (Positron Emission Tomogaphy). Recently, many researchers have given significant amount of effort to develop and improve imaging techniques for radiation therapy to enhance the overall quality of patient care. For example, advances in medical imaging technology have initiated the development of the state of the art radiation therapy techniques such as intensity modulated radiation therapy (IMRT), gated radiation therapy, tomotherapy, and image guided radiation therapy (IGRT). Capability of determining the local tumor volume and location of the tumor has been significantly improved by applying single or multi-modality imaging fur static or dynamic target. The use of multi-modality imaging provides a more reliable tumor volume, eventually leading to a better definitive local control. Image registration technique is essential to fuse two different image modalities and has been In significant improvement. Imaging equipments and their common applications that are in active use and/or under development in radiation therapy are reviewed.