• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.781-784
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• 2012

The aim of this study was to evaluate the effect of the adenovirus-mediated double suicide gene (CD/TK) for selective killing of gastric cancer cells. Gastric cancer cells SCG7901 and normal gastric epithelial cell lines were infected by adenoviruses Ad-survivin/GFP and Ad-survivin/CD/TK. GFP expression and CD-TK were detected by fluorescence microscopy and reverse transcriptase polymerase chain reaction (RT-PCR), respectively. After treatment of the infected cells with the pro-drugs ganciclovir (GCV) and/or 5-FC, the cell growth status was evaluated by methyl thiazolyl tetrazolium assay. Cell cycle changes were detected using flow cytometry. In nude mice bearing human gastric cancer, the recombinant adenovirus vector was injected directly into the tumor followed by an intraperitoneal injection of GCV and/or 5-FC. The subsequent tumor growth was then observed. The GFP gene driven by survivin could be expressed within the gastric cancer line SCG7901, but not in normal gastric epithelial cells. RT-PCR demonstrated the presence of the CD/TK gene product in the infected SCG7901 cells, but not in the infected normal gastric epithelial cells. The infected gastric cancer SCG7901, but not the gastric cells, was highly sensitive to the pro-drugs. The CD/TK fusion gene system showed significantly greater efficiency than either of the single suicide genes in killing the target cells (P<0.01). Treatment of the infected cells with the pro-drugs resulted in increased cell percentage in G0-Gl phase and decreased percentage in S phase. In nude mice bearing SCG7901 cells, treatment with the double suicide gene system significantly inhibited tumor growth, showing much stronger effects than either of the single suicide genes (P<0.01). The adenovirus-mediated CD/TK double suicide gene driven by survivin promoter combined with GCV an 5-FC treatment could be an effective therapy against experimental gastric cancer with much greater efficacy than the single suicide gene CD/TK combined with GCV or 5-FC.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.8
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• pp.799-804
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• 2011

The LFLP (Linear Fresnel Light Pipe) system uses a linear Fresnel lens to follow the sun and concentrates the parallel sunlight into a line. A LFLP daylighting system has been developed and updated to a DBLP (Double Blind Light Pipe) daylighting system to improve the overall system efficiency in the morning and afternoon. The new design consists of a double-blind style with a cone-shaped light transformer. The blinds are used to collect the sun's altitude and azimuth movements through the day. Behind the two sets of blinds is the light transformer, which is based on a parabolic-shaped light concentrator. The light transformer is designed to efficiently deliver light within a thirty-degree radial spread so that the light pipe can internally reflect the light. The results of scale-model tests are encouraging, and the efficiency is three times higher than that of the previous LFLP system.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.2
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• pp.252-258
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• 2017

In this paper, the bandwidth and gain enhancement of a double-dipole quasi-Yagi antenna (DDQYA) using a modified balun and two directors is studied. The proposed DDQYA consists of two strip dipoles with different lengths, a ground reflector, which are connected through a coplanar strip line, and two directors. The modified balun is used to increase the bandwidth, whereas two directors are appended to the DDQYA to enhance the gain in the middle and high frequency band. The effects of the length and width of the first director on the antenna performance are analyzed, and final design parameters to obtain a gain over 7 dBi at 1.60-2.90 GHz band are obtained. A prototype of the proposed DDQYA is fabricated on an FR4 substrate, and the experimental results show that the antenna has a frequency band of 1.57-3.00 GHz for a VSWR < 2, and measured gain ranges 7.1-7.8 dBi at 1.60-2.90 GHz band.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.50 no.3
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• pp.351-360
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• 2014

The experiments were carried out to decide the selective fishing gear of the shrimp beam trawl fishery. The model nets were made of General type, Double-level type and Grid type. The model experiments were carried out to test opening efficiency and towing tension. The experimental tanks were the flume tank [$8.0L{\times}2.8W{\times}1.4H(m)$] and the towing tank [$85L{\times}10W{\times}3.5H(m)$] in National Fisheries Research and Development Institute. The full scale experiments were carried out to compare the selectivity of General type net, Double-level type net and Grid type net in the southern sea of korea. The vertical opening (net height) of the model nets can be expressed as a function of the towing velocity as the straight line. The towing tension of the model nets can be expressed as a function of the towing velocity as the parabola. The shrimp catching rates of upper cod end in Boryeong and tongyeong were 78%, 9% respectively, but the rates of lower cod end were 23%, 91% respectively. The number bycatch rates of General type and Grid type were 23%, 11% respectively, and the weight bycatch rates were 34%, 31% respectively. A selective shrimp beam trawl net is Grid type in korea coastal sea.

• Journal of KSNVE
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• v.7 no.4
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• pp.597-604
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• 1997

Ground vibrations induced from railroad were measured to get the basic data that can be usde to prepare countermeasures for solving environmental vibration problems. Vibration levels were measured simultaneously at three points in double distances from railroad. These data were analuzed with the kinds of trains, media to understand the magnitudes and characteristics of distance attenuation of railroad vibrations.

• Journal of the Korean Professional Engineers Association
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• v.34 no.4
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• pp.17-29
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• 2001

After participating in the 2nd, Asian Civil Engineering Conference which is subjected by Japan, a trip of site during construction recent was done. The country Is being developed to use effectvely by the methods of aqua-line, truss suspersion bridge. double deck bridge, etc. The Japanese engineers have a pride to do their best for the construction In the given environment. 1 want to notify that our civil engineers must have the responsibility to develop the technical engineering, to make the useful country and to resolve the environmental problem via the oversea experience like as.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1998.11a
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• pp.69-72
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• 1998

A study to identify the energized status of the 22.9kV underground power cable by the detection of vibration was reformed. We derived that there exists vibration at double the line frequency in live cables by electromagnetic force. The vibration can be picked up by accelerometer sensor. A prototype was tested on the underground distribution system in Chonan Station, KEPCO. The results are presented and suggest the applicability of the detecting device.

• Proceedings of the IEEK Conference
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• 1998.06a
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• pp.526-529
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• 1998

This paper describes new sense amplifier with fast sensing delay time of 0.54ns and 32kb CMOS embedded SRAM with 4.67ns access time for a 3-V powr supply. It was achieved using the sense amplifier with multiple point sensing scheme and high speed bit-line scheme. The sense amplifier saves 25% of the power dissipation compared with the conventional one while maintaining a very short sensing delay. The SRAM uses 0.5.mu.m double-polysilicon and triplemetal CMOS process technology. A die size is 1.78mm*2.13mm.

• Proceedings of the KIEE Conference
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• 2001.05a
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• pp.254-258
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• 2001

In this paper, 3-dimensional charge simulation method was developed to analyze electric field distributions of special conductor bundles equipped with spiral rods for reducing aeolian noise. When we applied this method to 765 kV double circuit transmission line, we found calculation error of this method was within a reasonable boundary of 1%.

• Journal of the Korean Society of Costume
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• v.38
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• pp.73-82
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• 1998

There are two styles of Yoo(; ) Sang(;裳) in Koryo Women. One they wore the Snag(;裳) over the Yoo(; ), the other wore the Yoo(; ) over the Sang(;裳). In the Yoo(; ), Double breast styly was used for the adjustments of these clothes, Neckline and hem line were substituted by rectangular collar (;목판깃). Knot-button, Coat-string(;Okgolum), White straight collar (DongJung), side slit were used. In the Sang(;裳), Chimaheri(;치마허리)was mades of another fabric and Chima-string was dropped.