• 제목/요약/키워드: Double Well Function

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유전자 발현 조절과 DNA 3차원적 구조와의 관계 (Regulation of Gene Expression and 3-Dimensional Structure of DNA)

  • 김병동
    • 한국식물학회:학술대회논문집
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    • 한국식물학회 1987년도 식물생명공학 심포지움 논문집 Proceedings of Symposia on Plant Biotechnology
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    • pp.149-155
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    • 1987
  • Growth and development of a higher plant, or any living organism for that matter, could be defined as an orderly expression of the genome in time and space in close interaction with the environment. During differentiation and development of a tissue or organ a group of genes must be selectively turned on or turned off mainly by trans-acting regulators. In this general concept of regulation of regulation of gene expression, a DNA molecule is recognized at a specific nucleotide sequence by DNA-binding factors. Molecular biology of the regulatory factors such as hormones, and their receptors, target DNA sequences and DNA-binding proteins are well advanced. What is not clearly understood is the molecular basis of the interactions between DNA and binding factors, expecially of the usages of the dyad symmetry of the target DNA sequences and the dimeric nature of the DNA-binding proteins. A unique 3-dimensional structure of DNA has been proposed that may play an important role in the orderly expression of the gene. A foldback intercoil (FBI) DNA configuration which was originally found by electron microscopy among mtDNA molecules from pearl millet has some unique features. The FBI configuration of DNA is believed to be formed when a flexible double helix folds back and interwines in the widened major grooves resulting in a four stranded, intercoil DNA whose thickness is the same as that of double stranded DNA. More recently, the FBI structure of DNA has been also induced in vitro by a novel enzyme which was purified from pearl millet mitochondria. It has been proposed that the FBI DNA could be utillized in intramolecular recombination which leads to inversion or deletion, and in intermolecular recombination which can lead to either site-specific recombination, genetic recombination via single strand invasion, or cross strand recombination. The structure and function of DNA in 3-dimensional aspect is emphasized for better understanding orderly expression of genes during growth and development.

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Simplified Noise Modeling of GPS Measurements for a Fast and Reliable Cycle Ambiguity Resolution

  • Park, Byung-Woon;Kee, Chang-Don
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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    • pp.535-540
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    • 2006
  • The relationship between the observable noise model and the satellite elevation angle can be modeled quite well by an exponential function.[Jin, 1996] Noise size and dependence on the elevation angle are, however, different for each observation and receiver type. Therefore, the coefficient determination of this model is an issue, and various methods including PR-CP, single difference, and time difference have been suggested. The limitations of them are difficulty to model the carrier phase noise and to eliminate bias. To overcome these disadvantages for using Jin's model, we suggest zero baseline double difference (DD) and noise sorting algorithm. Data DD technique in zero baseline is useful to eliminate all the troublesome GPS biases, and the remaining error is the sum of GPS measurement noises from two satellites. These DD residuals for hours should be sorted by the combination of satellite elevation angles, and then variance value of the residual for each combination can be estimated. Using these values, we construct an over-determined linear equation whose solution is a set of noise variance for each satellite elevation angle. With 24hr Trimble 4000ssi data, we easily worked out the coefficients of the noise model not only for pseudorange but also for carrier phase. We estimated the standard deviation of the measurement DD using our model, and plotted 1 and 3 sigma lines for every epoch to verify the representation of the residual error. 63.3% of pseudorange residual and 65.9% of phase error did not exceed the 1 sigma lines. Additionally, 99.2% and 99.5% of them lied within 3sigma line. These figures prove that the Gaussian property of measurement noise, and that the suggested model by our algorithm corresponds to the observable noise information.

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이차원 전위분포모델을 이용한 이중게이트 MOSFET의 항복전압 분석 (Analysis of Breakdown Voltages of Double Gate MOSFET Using 2D Potential Model)

  • 정학기
    • 한국정보통신학회논문지
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    • 제17권5호
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    • pp.1196-1202
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    • 2013
  • 본 연구에서는 이중게이트 MOSFET에 대한 항복전압의 변화를 채널도핑 및 소자파라미터에 따라 이차원 전위분포모델을 이용하여 분석한 것이다. 낮은 항복전압은 전력소자동작에 저해가 되고 있으며 소자의 크기가 감소하면서 발생하는 단채널 효과에 의하여 이중게이트 MOSFET의 경우도 심각하게 항복전압이 감소하고 있다. 항복전압분석을 위하여 포아송방정식의 이차원 해석학적 전위분포모델을 이용하여 채널도핑농도와 소자 파라미터인 채널길이, 채널두께, 게이트산화막 두께 등에 대하여 항복전압의 변화를 관찰하였다. 분석결과 항복전압은 채널도핑 농도의 크기뿐만이 아니라 소자크기 파라미터에 대해서 커다란 변화를 보이고 있었으며 특히 채널도핑함수인 가우시안 함수의 형태에 따라서도 큰 변화를 보이고 있다는 것을 관찰할 수 있었다.

Hash Based Equality Analysis of Video Files with Steganography of Identifier Information

  • Lee, Wan Yeon;Choi, Yun-Seok
    • 한국컴퓨터정보학회논문지
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    • 제27권7호
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    • pp.17-25
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    • 2022
  • 해시 함수는 입력 크기와 상관없는 고정된 작은 출력 크기로 인해서, 최근 들어 동영상 파일들의 해시 출력 값들을 빠르게 비교하는 동일성 검사에 널리 사용되고 있다. 그러나 해시 함수는 상이한 입력들이 동일한 출력 값을 도출하는 해시 충돌 가능성이 존재하여, 상이한 동영상 파일들을 동일한 파일로 오인할 수 있는 문제가 존재한다. 본 논문에서는 구별자 정보와 이중 해시를 이용하여 상이한 동영상 파일들은 항상 다르게 판단하는 동일성 검사 기법을 제안하였다. 제안된 기법은 먼저 원본 동영상 파일에서 구별자 정보를 추출하고, 이 구별자 정보를 원본 동영상에 은닉하여 추가하는 확장 파일을 생성한다. 그리고 구별자 정보, 원본 파일의 해시 출력 값, 확장 파일의 해시 출력 값을 사용하여 파일의 동일성 검사를 수행한다. 제안된 기법의 성능 평가를 위해서 실제 프로그램으로 구현하였고, 해시 충돌 없이 동영상 파일의 동일성 검사를 잘 수행하고 또한 인위적 해시 충돌 공격에도 뛰어난 내성을 가짐을 확인하였다.

Optimal Particle Swarm Based Placement and Sizing of Static Synchronous Series Compensator to Maximize Social Welfare

  • Hajforoosh, Somayeh;Nabavi, Seyed M.H.;Masoum, Mohammad A.S.
    • Journal of Electrical Engineering and Technology
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    • 제7권4호
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    • pp.501-512
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    • 2012
  • Social welfare maximization in a double-sided auction market is performed by implementing an aggregation-based particle swarm optimization (CAPSO) algorithm for optimal placement and sizing of one Static Synchronous Series Compensator (SSSC) device. Dallied simulation results (without/with line flow constraints and without/with SSSC) are generated to demonstrate the impact of SSSC on the congestion levels of the modified IEEE 14-bus test system. The proposed CAPSO algorithm employs conventional quadratic smooth and augmented quadratic nonsmooth generator cost curves with sine components to improve the accurate of the model by incorporating the valve loading effects. CAPSO also employs quadratic smooth consumer benefit functions. The proposed approach relies on particle swarm optimization to capture the near-optimal GenCos and DisCos, as well as the location and rating of SSSC while the Newton based load flow solution minimizes the mismatch equations. Simulation results of the proposed CAPSO algorithm are compared to solutions obtained by sequential quadratic programming (SQP) and a recently implemented Fuzzy based genetic algorithm (Fuzzy-GA). The main contributions are inclusion of customer benefit in the congestion management objective function, consideration of nonsmooth generator characteristics and the utilization of a coordinated aggregation-based PSO for locating/sizing of SSSC.

소의 조기 임신진단 kit의 개발 II. 조기 임신진단 kit의 개발 (A study on production of early pregnancy diagnostic kit in cattle II. Production of early pregnancy diagnostic kit)

  • 강정부;이행종;최상용
    • 대한수의학회지
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    • 제31권2호
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    • pp.223-228
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    • 1991
  • Most progesterone enzyme immunoassays(EIA) are used liquid-phase double-antibody or single-antibody seperation. These methods consume considerable time and reagents because of the requirements for several washing and centrifugation steps involving the reactants. Because of these several problems, we were prompted to develop an effective enzyme-linked immunosorbent assay(ELISA) system that would be equal or superior to RIA for assay of progesterone. The results were obtained as follows. 1. Cross reaction of the progesterone antiserum with other steroids determined was shown with progesterone(100%), $11{\alpha}$-deoxycorti-costerone(2.271%), but the other steroids were shown below 0.9%. 2. Standard curve for progesterone ELISA was shown available difference according to progesterone concentration from 0 to 1,000pg/ml. 3. The lower limit of sensitivity was 0.2pg/well 4. Progesterone concentration was 1.6ng/ml for before parturition, and that was below 0.5ng/ml for after parturition. This development enzyme-linked immunosorbent assay for progesterone can be detected pregnancy diagnosis in cattle, and also applicable 10 research on physiological function including such as reproductive disorders.

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뇌졸중환자의 동작관찰 보행훈련이 시·공간적 지표와 재활동기에 미치는 영향 (Effects of Observed Action Gait Training on Spatio-temporal Parameter and Motivation of Rehabilitation in Stroke Patients)

  • 강권영
    • 대한물리의학회지
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    • 제8권3호
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    • pp.351-360
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    • 2013
  • PURPOSE: The purpose of this study was to investigate the effects of observed action gait training on stroke patients. METHODS: 22 subjects were randomized into two groups. The observed action gait training performed that watched a video of normal gait before gait training and the general gait training without watching it. The experimental group(n=11) performed observed action gait training and the control group(n=11) performed general gait training. Both group received gait training for 3 times per week during 8 weeks. RESULTS: The experimental group showed significant differences in the cadence, gait velocity, stride, step, single limb support, double limb support, stride length and step length(p<.05). The control group showed significant differences only in the stride(p<.05). CONCLUSION: The observed action gait training affected coordination and weight shift, as well as symmetry of the body. Plasticity of the brain was facilitated by repetitive visual and sensory stimulation. The observed action gait training promoted the normal gait by watching the normal gait pattern. In conclusion, motor learning through the sensory stimulation promotes brain plasticity that could improve motor function, and observed action gait training indirectly identified stimulated brain activities.

Joint Transmitter and Receiver Optimization for Improper-Complex Second-Order Stationary Data Sequence

  • Yeo, Jeongho;Cho, Joon Ho;Lehnert, James S.
    • Journal of Communications and Networks
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    • 제17권1호
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    • pp.1-11
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    • 2015
  • In this paper, the transmission of an improper-complex second-order stationary data sequence is considered over a strictly band-limited frequency-selective channel. It is assumed that the transmitter employs linear modulation and that the channel output is corrupted by additive proper-complex cyclostationary noise. Under the average transmit power constraint, the problem of minimizing the mean-squared error at the output of a widely linear receiver is formulated in the time domain to find the optimal transmit and receive waveforms. The optimization problem is converted into a frequency-domain problem by using the vectorized Fourier transform technique and put into the form of a double minimization. First, the widely linear receiver is optimized that requires, unlike the linear receiver design with only one waveform, the design of two receive waveforms. Then, the optimal transmit waveform for the linear modulator is derived by introducing the notion of the impropriety frequency function of a discrete-time random process and by performing a line search combined with an iterative algorithm. The optimal solution shows that both the periodic spectral correlation due to the cyclostationarity and the symmetric spectral correlation about the origin due to the impropriety are well exploited.

정중선 이소성 갑상선에서 주사상의 변화 추적 - 증례보고 - (A Changing Pattern of Isotope Scan of the Midline Ectopic Thyroid - A Case Report -)

  • 김갑태;김완섭;정을삼
    • Advances in pediatric surgery
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    • 제2권2호
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    • pp.133-137
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    • 1996
  • A 17 month-old girl presented in the pediatric clinic on November 27th, 1990 with a neck mass. The mass was 2 cm in diameter, firm in consistency and movable on the upper pole of the thyroid cartilage in the midline. The technetium thyroid scan showed a hot reactivity at the compatible site of the mass, but no other radioactivity in either site of the normal thyroid positions. At her second visit on January 23th, 1996, the mass had enlarged up to 3.5cm in diameter in the same location of the neck. The follow up thyroid scan revealed a walnut sized, snowman-like radioactivity. One of the snowman-like double images seemed to be a lingual ectopic thyroid and the other a midline ectopic thyroid remnant in the infrahyoid level. This interpretation was supported by the computed tomography of the neck, which showed a ligual mass in the foramen cecum area and an another mass in the anterior comis-sure of the larynx in the mildline. Thyroid function test was normal except a slightly increased TSH. As a result of this changing pattern of thyroid radioactive images, a case of a lingual thyroid as well as another midline ectopic thyroid tissue at the infrahyoid level is reported.

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비틀림 하중을 받는 얇은 빔의 동적 불안정성에 관한 연구 (Study on the Dynamic Torsional Instability of a Thin Beam)

  • 박진선;주재만;박철희
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 1995년도 추계학술대회논문집; 한국종합전시장, 24 Nov. 1995
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    • pp.185-190
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    • 1995
  • In recent years, many researcher have been interested in the stability of a thin beam. Among them, Pai and Nayfeh[1] had investigated the nonplanar motion of the cantilever beam under lateral base excitation and chaotic motion, but this study is associated with internal resonance, i.e. one to one resonance. Also Cusumano[2] had made an experiment on a thin beam, called Elastica, under bending loads. In this experiment, he had shown that there exists out-of-plane motion, involving the bending and the torsional mode. Pak et al.[3] verified the validity of Cusumano's experimental works theoretically and defined the existence of Non-Local Mode(NLM), which is came out due to the instability of torsional mode and the corresponding aspect of motions by using the Normal Modes. Lee[4] studied on a thin beam under bending loads and investigated the routes to chaos by using forcing amplitude as a control parameter. In this paper, we are interested in the motion of a thin beam under torsional loads. Here the form of force based on the natural forcing function is used. Consequently, it is found that small torsional loads result in instability and in case that the forcing amplitude is increasing gradually, the motion appears in the form of dynamic double potential well, finally leads to complex motion. This phenomenon is investigated through the poincare map and time response. We also check that Harmonic Balance Method(H.B.M.) is a suitable tool to calculate the bifurcated modes.

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