• 제목/요약/키워드: Double Well Function

검색결과 126건 처리시간 0.029초

대혈관 변위를 동반한 선천성 복잡심기형에 대한 동맥전환술 (Arterial switch operation for the complex congenital heart anomalies with malposition of the great arteries)

  • 이정렬
    • Journal of Chest Surgery
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    • 제26권1호
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    • pp.36-43
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    • 1993
  • Sixty four children [aged 2 days to 9 years] , 58 with complete transposition of the great arteries, 5 with Taussig-Bing double outlet right ventricle, and 1 with double outlet left ventricle plus left ventricular type single ventricle, have undergone anatomic correction from November 1987 to August 1992. Eleven underwent previous operations: pulmonary artery banding[7], modified Blalock-Taussig shunt[2], coarctoplasty[2], aortic arch reconstruction[1] . Of 58 patients with TGA, Type A coronary arteries of Yacoub were seen in 50[86%]. U-shaped coroanry arterial flaps were transfered to the neoaorta using trap door technique, and neopulmonary arterial tract was constructed using glutaraldehyde fixed autopericardium with Lecompte maneuver. There were 18 hospital deaths [28.1%] with no late mortality. Mean follow-up of 20.4\ulcorner11.9 months were achieved in all survivors. Postoperative cardiac catheterizations were done in 14 cases. Mean pressure gradients of pulmonary and aortic outflow tract were 15.0 $\pm$2.6 and 4.2$\pm$1.4mmHg, mild aortic valve insufficiencies were found in 2, and mean cardiac index was 5.18$\pm$0.19 L/min/M2. We conclude that we should continue anatomic correction for the complex congenital heart anomalies with the malposition of the great arteries because myocardial function seems to be well preserved, though we are still on the learning curve.

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Electrokinetic flow and electroviscous effect in a charged slit-like microfluidic channel with nonlinear Poisson-Boltzmann field

  • Chun, Myung-Suk;Kwak, Hyun-Wook
    • Korea-Australia Rheology Journal
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    • 제15권2호
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    • pp.83-90
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    • 2003
  • In cases of the microfluidic channel, the electrokinetic influence on the transport behavior can be found. The externally applied body force originated from the electrostatic interaction between the nonlinear Poisson-Boltzmann field and the flow-induced electrical field is applied in the equation of motion. The electrostatic potential profile is computed a priori by applying the finite difference scheme, and an analytical solution to the Navier-Stokes equation of motion for slit-like microchannel is obtained via the Green's function. An explicit analytical expression for the induced electrokinetic potential is derived as functions of relevant physicochemical parameters. The effects of the electric double layer, the zeta potential of the solid surface, and the charge condition of the channel wall on the velocity profile as well as the electroviscous behavior are examined. With increases in either electric double layer or zeta potential, the average fluid velocity in the channel of same charge is entirely reduced, whereas the electroviscous effect becomes stronger. We observed an opposite behavior in the channel of opposite charge, where the attractive electrostatic interactions are presented.

이중 해시체인 기반의 명령어 메시지 인증 메커니즘 설계 (Design of Authentication Mechinism for Command Message based on Double Hash Chains)

  • 박왕석;박창섭
    • 융합보안논문지
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    • 제24권1호
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    • pp.51-57
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    • 2024
  • 최근 산업제어시스템은 정보기술과 운영기술을 융합하는 Industrial IoT의 도입과 함께 진화를 계속하고 있지만, 과거에는 경험하지 못한 다양한 사이버 공격 역시 증가하고 있다. 제어센터에서 전송되는 다양한 명령어 메시지를 통해 시스템을 구성하는 필드 디바이스들에 대한 모니터링 및 운영 제어가 행해지기에 명령어 메시지에 대한 무결성과 더불어 제어센터에 대한 인증은 필수 요구사항이 되고 있다. 기존의 대칭키 기반의 메시지인증코드 방식 또는 공개키 기반의 서명 방식은 제어센터 그리고 자원 제약적 필드 디바이스의 비대칭성에 따른 적용상의 제약들이 존재한다. 특히, 대칭키 방식에서는 필드 디바이스에 설치된 대칭키가 공격자에게 노출되면 시스템 전반적인 보안 문제점이 발생한다. 본 논문에서는 명령어 메시지를 구성하는 구성 필드들이 취할 수 있는 데이터 값들이 제한적(낮은 엔트로피)이라는 점에 착안하여 암호해시함수로 구축된 이중 해시체인을 통한 메시지 인증기법을 제안한다. 한 쌍의 이중 해시체인은 오직 한 개의 명령어 메시지에 적용되기에 다중 사용을 위한 Merkle 트리에 기반을 둔 확장 기법 역시 제안한다. 메시지 인증을 위해 암호해시함수 이외의 암호 프리미티브는 사용이 안되기에 계산 복잡도는 매우 낮게 유지될 수 있음을 성능평가를 통해 확인한다.

영상센서신호의 잡음분석을 이용한 위성용 전자광학탑재체의 신호대잡음비 개선 방법 (The Signal-to-Noise Ratio Enhancement of the Satellite Electro-Optical Imager using Noise Analysis Methods)

  • 박종억;이기준
    • 대한원격탐사학회지
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    • 제33권2호
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    • pp.159-169
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    • 2017
  • 위성용 전자광학탑재체는 제한된 소모전력 및 우주방사선과 같은 사용 환경에 의해 설계부터 특별한 요구사항을 가지고 있으며, 획득 영상의 품질은 주로 GSD (Ground Sampled Distance), 신호대잡음비(SNR, Signal to Noise Ratio), MTF (Modulation Transfer Function)에 따라 좌우된다. 영상센서의 출력신호에 포함된 잡음 감소를 통한 신호대잡음비 개선을 위하여, 센서에 추가된 프리픽셀(Pre-pixel) 및 다크픽셀(Dark-pixel)을 사용하여 CDS (Corrective Double Sampling) 방식을 통해 영상센서의 잡음 성분을 포함한 오프셋 신호(Offset Signal)를 제거하는 아날로그 신호처리(ASP, Analog Signal Processor) 방법을 제안한다. 또한 센서 제어시스템에서는 영상의 불균일성 처리를 위해 제어시스템의 출력 포트별 게인(Gain), 오프셋, 및 센서의 화소별 특성을 반영한 다양한 방식에 의한 보정 방법이 적용된다. 본 논문에서는 이상 설명한 여러 가지 잡음 개선방법을 시스템 설계 및 운영에 적용하여 위성탑재용 전자광학카메라의 신호대잡음비 향상 방법을 제안하고, 실험을 통해 검증한다.

실험계획법을 이용한 전륜 토우각의 최적설계 및 조종 안정성능 평가 시뮬레이션 (Optimum Design of Front Toe Angle Using Design of Experiment and Dynamic Simulation for Evaluation of Handling Performances)

  • 서권희;민한기;천인범
    • 한국자동차공학회논문집
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    • 제8권2호
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    • pp.120-128
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    • 2000
  • At the initial design stage of a new vehicle, the chassis layout has the most important influence on the overall vehicle performance. Most chassis designers have achieved the target performances by trial and error method as well as individual knowhow. Accordingly, a general procedure for determining the optimum location of suspension hard points with respect to the kinematic characteristics needs to be developed. In this paper, a method to optimize the toe angle in the double wishbone type front suspension of the four-wheel-drive vehicle is presented using the design of experiment, multibody dynamic simulation, and optimum design program. The handling performances of two full vehicle models having the initial and optimized toe angle are compared through the single lane change simulation. The sensitive design variables with respect to the kinematic characteristics are selected through the experimental design sensitivity analysis using the perturbation method. An object function is defined in terms of the toe angle among those kinematic characteristics. By the design of experiment and regression analysis, the regression model function of toe angle is obtained. The design variables which make the toe angle optimized ae extracted using the optimum design program DOT. The single lane change simulation and test of the full vehicle model are carried out to survey the handling performances of vehicle with toe angle optimized. The results of the single lane change simulation show that the optimized vehicle has the more improved understeer tendency than the initial vehicle.

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승자전취 메커니즘 방식의 아날로그 연상메모리 (An Analog Content Addressable Memory implemented with a Winner-Take-All Strategy)

  • 채용웅
    • 한국전자통신학회논문지
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    • 제8권1호
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    • pp.105-111
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    • 2013
  • 선형적인 읽기와 쓰기 특성을 가지고 있는 승자전취메커니즘 방식의 아날로그 메모리를 구현하였다. 메모리의 읽기 동작은 연상메모리의 최적 함수 선택을 위하여 절대값 회로와 승자전취메커니즘 회로가 이용된다. 본 연구에서는 병렬의 고속 쓰기와 읽기 동작뿐만 아니라 고집적을 가능하게 하는 시스템 구성이 실현된다. 복수의 메모리 셀의 구현이 더 높은 집적도와 고속의 쓰기 읽기를 위하여 구현된다. 실시간 인식을 위하여 본 연구에서 사용된 함수는 이상적이며 메커니즘의 시뮬레이션을 위하여 MOSIS의 $1.2{\mu}$ 더블폴리 CMOS 공정 파라미터를 사용하였다.

Structural and Functional Insight into Proliferating Cell Nuclear Antigen

  • Park, So Young;Jeong, Mi Suk;Han, Chang Woo;Yu, Hak Sun;Jang, Se Bok
    • Journal of Microbiology and Biotechnology
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    • 제26권4호
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    • pp.637-647
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    • 2016
  • Proliferating cell nuclear antigen (PCNA) is a critical eukaryotic replication accessory factor that supports DNA binding in DNA processing, such as DNA replication, repair, and recombination. PCNA consists of three toroidal-shaped monomers that encircle double-stranded DNA. The diverse functions of PCNA may be regulated by its interactions with partner proteins. Many of the PCNA partner proteins generally have a conserved PCNA-interacting peptide (PIP) motif, located at the N- or C- terminal region. The PIP motif forms a 310 helix that enters into the hydrophobic groove produced by an interdomain-connecting loop, a central loop, and a C-terminal tail in the PCNA. Post-translational modification of PCNA also plays a critical role in regulation of its function and binding partner proteins. Structural and biochemical studies of PCNA-protein will be useful in designing therapeutic agents, as well as estimating the outcome of anticancer drug development. This review summarizes the characterization of eukaryotic PCNA in relation to the protein structures, functions, and modifications, and interaction with proteins.

Discriminant Analysis of Marketed Liquor by a Multi-channel Taste Evaluation System

  • Kim, Nam-Soo
    • Food Science and Biotechnology
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    • 제14권4호
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    • pp.554-557
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    • 2005
  • As a device for taste sensation, an 8-channel taste evaluation system was prepared and applied for discriminant analysis of marketed liquor. The biomimetic polymer membranes for the system were prepared through a casting procedure by employing polyvinyl chloride, bis (2-ethylhexyl)sebacate as plasticizer and electroactive materials such as valinomycin in the ratio of 33:66:1, and were separately attached over the sensitive area of ion-selective electrodes to construct the corresponding taste sensor array. The sensor array in conjunction with a double junction reference electrode was connected to a high-input impedance amplifier and the amplified sensor signals were interfaced to a personal computer via an A/D converter. When the signal data from the sensor array for 3 groups of marketed liquor like Maesilju, Soju and beer were analyzed by principal component analysis after normalization, it was observed that the 1st, 2nd and 3rd principal component were responsible for most of the total data variance, and the analyzed liquor samples were discriminated well in 2 dimensional principal component planes composed of the 1st-2nd and the 1st-3rd principal component.

정규모우드 방법을 활용한 진자형 흡진기의 비선형 동역학에 관한 연구 (On the Normal Mode Dynamics of a Pendulum Absorber)

  • 심재구;박철희
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 1996년도 춘계학술대회논문집; 부산수산대학교, 10 May 1996
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    • pp.177-183
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    • 1996
  • By utilizing the concept of normal modes, nonlinear dynamics is studied on pendulum dynamic absorber. When the spring mode loses the stability in undamped free system, a dynamic two-well potential is formed in Poincare map. A procedure is formulated to compute the forced responses associated with bifurcating mode and predict double saddle-loop phenomenon. It is found that quasiperiodic motion and stable periodic motion coexist in some parameter ranges, and only periodic motions or rotation of pendulum with chaotic fluctuation are observed in other ranges.

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RESURE LDMOS의 항복전압에 관한 이론적인 고찰 (A theoretical study on the breakdown voltage of the RESURF LDMOS)

  • 한승엽;정상구
    • 전자공학회논문지D
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    • 제35D권8호
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    • pp.38-43
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    • 1998
  • An analytical model for the surface field distribution of the RESURF (reduced surface field)LD(lateral double-diffused) MOS is presented in terms of the doping concentration, the thickness of the n epi layer, the p substrate concentration, and the epi layer length. The reuslts are used to determine the breakdown voltage due to the surface field as a function of the epi layer length. The maximum breakdown voltage of the device is found to be that of the vertical n$^{+}$n$^{[-10]}$ p$^{[-10]}$ junction. Analytical results of the breakdown voltage vs. the epi layer length agree well with the numerical simulation results using MEDICI.I.

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