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Organ Dose Conversion Coefficients Calculated for Korean Pediatric and Adult Voxel Phantoms Exposed to External Photon Fields

  • Lee, Choonsik;Yeom, Yeon Soo;Griffin, Keith;Lee, Choonik;Lee, Ae-Kyoung;Choi, Hyung-do
    • Journal of Radiation Protection and Research
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    • v.45 no.2
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    • pp.69-75
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    • 2020
  • Background: Dose conversion coefficients (DCCs) have been commonly used to estimate radiation-dose absorption by human organs based on physical measurements of fluence or kerma. The International Commission on Radiological Protection (ICRP) has reported a library of DCCs, but few studies have been conducted on their applicability to non-Caucasian populations. In the present study, we collected a total of 8 Korean pediatric and adult voxel phantoms to calculate the organ DCCs for idealized external photon-irradiation geometries. Materials and Methods: We adopted one pediatric female phantom (ETRI Child), two adult female phantoms (KORWOMAN and HDRK Female), and five adult male phantoms (KORMAN, ETRI Man, KTMAN1, KTMAN2, and HDRK Man). A general-purpose Monte Carlo radiation transport code, MCNPX2.7 (Monte Carlo N-Particle Transport extended version 2.7), was employed to calculate the DCCs for 13 major radiosensitive organs in six irradiation geometries (anteroposterior, posteroanterior, right lateral, left lateral, rotational, and isotropic) and 33 photon energy bins (0.01-20 MeV). Results and Discussion: The DCCs for major radiosensitive organs (e.g., lungs and colon) in anteroposterior geometry agreed reasonably well across the 8 Korean phantoms, whereas those for deep-seated organs (e.g., gonads) varied significantly. The DCCs of the child phantom were greater than those of the adult phantoms. A comparison with the ICRP Publication 116 data showed reasonable agreements with the Korean phantom-based data. The variations in organ DCCs were well explained using the distribution of organ depths from the phantom surface. Conclusion: A library of dose conversion coefficients for major radiosensitive organs in a series of pediatric and adult Korean voxel phantoms was established and compared with the reference data from the ICRP. This comparison showed that our Korean phantom-based data agrees reasonably with the ICRP reference data.

Spats Appearance and Distribution of Blood Cockle, Tegillarca granosa in Each Tidal Time and Line (노출선별 꼬막, Tegillarca granosa 치패의 출현과 분포)

  • Moon Tae-Seok;Jung Min-Min;Yang Moon-Ho;Wi Chong-Hwan;Lee Jung-Ho;Shin Yean-Sik;Shin Yun-Kyung;Chang Young-Jin
    • Journal of Aquaculture
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    • v.19 no.2
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    • pp.119-124
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    • 2006
  • We investigated appearance tidal time and line of spats blood cockle, Tegillarca granosa. And we observed appearance individual numbers and shell growth of spats blood cockle, T. granosa on the several tidal lines and time for the highly valued aquaculture business. Most of the blood cockle spats distributed on the $2{\sim}3 $ hours tidal line. The shell growth was high on the $1{\sim}3$ hours tidal line. But we found small amount of spats on the $5{\sim}6$ hours tidal line. The shell length of spats became $4.7{\pm}1.0 mm$ in December, $5.2{\pm}1.2 mm$ in January, $5.4{\pm}0.9 mm$ in May, $8.5{\pm}0.8mm$ in June, $12.6{\pm}1.1 mm$ in July, $16.0{\pm}2.1 mm$ in August, $18.6{\pm}1.4 mm$ in September and $20.3{\pm}1.3 mm$ in October. As well, we could reconfirm of newly appearance blood cockle spats in the next October.

Analytical Consideration of Surface Dose and Kerma for Megavoltage Photon Beams in Clinical Radiation Therapy

  • Birgani, Mohammad Javad Tahmasebi;Behrooz, Mohammad Ali;Razmjoo, Sasan;Zabihzadeh, Mansour;Fatahiasl, Jafar;Maskni, Reza;Abdalvand, Neda;Asgarian, Zeynab;Shamsi, Azin
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.153-157
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    • 2016
  • Background: In radiation therapy, estimation of surface doses is clinically important. This study aimed to obtain an analytical relationship to determine the skin surface dose, kerma and the depth of maximum dose, with energies of 6 and 18 megavoltage (MV). Materials and Methods: To obtain the dose on the surface of skin, using the relationship between dose and kerma and solving differential equations governing the two quantities, a general relationship of dose changes relative to the depth was obtained. By dosimetry all the standard square fields of $5cm{\times}5cm$ to $40cm{\times}40cm$, an equation similar to response to differential equations of the dose and kerma were fitted on the measurements for any field size and energy. Applying two conditions: a) equality of the area under dose distribution and kerma changes in versus depth in 6 and 18 MV, b) equality of the kerma and dose at $x=d_{max}$ and using these results, coefficients of the obtained analytical relationship were determined. By putting the depth of zero in the relation, amount of PDD and kerma on the surface of the skin, could be obtained. Results: Using the MATLAB software, an exponential binomial function with R-Square >0.9953 was determined for any field size and depth in two energy modes 6 and 18MV, the surface PDD and kerma was obtained and both of them increase due to the increase of the field, but they reduce due to increased energy and from the obtained relation, depth of maximum dose can be determined. Conclusions: Using this analytical formula, one can find the skin surface dose, kerma and thickness of the buildup region.

Passive autocatalytic recombiner guide structure considering ambient flow (분위기 유동을 고려한 PAR 가이드 구조에 관한 연구)

  • Ryu, Myeong-Rok;Park, Kweon-Ha
    • Journal of Advanced Marine Engineering and Technology
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    • v.41 no.4
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    • pp.302-309
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    • 2017
  • If a hydrogen explosion occurs in a containment building, its multiplex defense wall may be destroyed and a large amount of radioactive material may be released. The hydrogen occurred interacting with melting fuel rods must be effectively controlled and removed. however, the countermeasures for reducing explosion risk are difficult to carry out, due owing to the various variety of accident scenarios causes and the irregularity of hydrogen distribution and behavior. In this study, We examine the guide structures while considering the ambient flows, in order to improve the efficiency of PAR the widely used Passive Autocatalytic Recombiner(PAR). We simulate the fluid behavior and the hydrogen reduction rate were simulated when a guide is attached to the two-step catalyst PAR. For an upward flow, the consisting of a height of 150mm, a gap of 0mm, and a performs $60^{\circ}$ showed the best. In contrast, for a sideways flow, a consisting of the height of 150mm, a gap of 100mm, and a performs $60^{\circ}$ showed the best in the case of side ward flow. for a downward flow, a consisting of the height of 50mm and a directly attached guide produce the best in the case of down ward flow results.

Distribution of spontaneously growing mushrooms in the Wolchulsan National Park (월출산국립공원의 자생버섯 분포상)

  • Ko, Pyung-Yeol;Lee, Seung-Hak;Kim, Tae-Heon;Choe, Suck-Young;Hong, Ki-Sung;Jeun, Yong-Chull
    • Journal of Mushroom
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    • v.18 no.3
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    • pp.201-207
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    • 2020
  • Mushrooms growing in the Wolchulsan National Park were surveyed from April to October 2018. As a result of this survey, 2 divisions, 9 classes, 24 orders, 71 families, 177 genera, and 407 species were found. Among them, 3 classes, 16 orders, 55 families, 150 genera, and 370 species belonged to Basidiomycota, while 6 classes, 8 orders, 16 families, 27 genera, and 37 species belonged to Ascomycota. The species richness was the highest in September at the altitudes between ~100 and 200 m. Among the investigated sites, the most diverse species occurred in the Gyeongpodae area. In this survey we found, Macrolepiota procera, Suillus bovinus, and Amanita pantherina, all of which have been known as climate-sensitive biological indicator species (CBIS). Based on the DNA sequence analyses, Craterellus parvogriseus was confirmed as a new record for Korea.

UHRF2 mRNA Expression is Low in Malignant Glioma but Silencing Inhibits the Growth of U251 Glioma Cells in vitro

  • Wu, Ting-Feng;Zhang, Wei;Su, Zuo-Peng;Chen, San-Song;Chen, Gui-Lin;Wei, Yong-Xin;Sun, Ting;Xie, Xue-Shun;Li, Bin;Zhou, You-Xin;Du, Zi-Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.5137-5142
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    • 2012
  • UHRF2 is a member of the ubiquitin plant homeo domain RING finger family, which has been proven to be frequently up-regulated in colorectal cancer cells and play a role as an oncogene in breast cancer cells. However, the role of UHRF2 in glioma cells remains unclear. In this study, we performed real-time quantitative PCR on 32 pathologically confirmed glioma samples (grade I, 4 cases; grade II, 11 cases; grade III, 10 cases; and grade IV, 7 cases; according to the 2007 WHO classification system) and four glioma cell lines (A172, U251, U373, and U87). The expression of UHRF2 mRNA was significantly lower in the grade III and grade IV groups compared with the noncancerous brain tissue group, whereas its expression was high in A172, U251, and U373 glioma cell lines. An in vitro assay was performed to investigate the functions of UHRF2. Using a lentivirus-based RNA interference (RNAi) approach, we down-regulated UHRF2 expression in the U251 glioma cell line. This down-regulation led to the inhibition of cell proliferation, an increase in cell apoptosis, and a change of cell cycle distribution, in which S stage cells decreased and G2/M stage cells increased. Our results suggest that UHRF2 may be closely related to tumorigenesis and the development of gliomas.

Clinical Studies on Thalamic Hemorrhage (시상출혈(視床出血)의 임상적(臨床的) 관찰(觀察))

  • Park, Chang-Gook
    • The Journal of Korean Medicine
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    • v.15 no.2 s.28
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    • pp.28-39
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    • 1994
  • Clinical studies were made on 79 cases with thalamic hemorrhage diagnosed by computed tomographic scan and only localized on the thalamic area, were admitted to the Kyung San University Taegu Oriental Medical Hospital from August 1990 to March 1994. The age and sex distribution, sites of hematoma, recurrence rate, incidence of hypertension, inducing factor, prodromal syndroms, symptoms and neurologic signs on admission, relationship between the hospital course and many factors affecting the prognosis such as age, side of hematoma, level of consciousness, volume of the hematoma. ventricular hemorrhage were analysed. The results were summarized as follows; 1. The most prevalent age group was above 60 years of age with 50-59 years, 70-79 years, 40-49 years and 80-89 years of age in the order of frequency. Male to female ratio was 1:1.55. 2. The ratio of left hematoma to the right was 1.32:1. The recurrence rate of cerebrovascular accident was 17.7% 3. The incidence of hypertension was 69.6% and inducing factors of thalamic hemorrhage in the order of frequency were physical work(29.1%), drinking or eating(13.9%), walking(12.7%) and rest(12.7%), The prodromal syndroms were numbness of extremities(5.1%), headache(2.5%), fatigue(2.5%), dizziness(1.3%), insomnia(1.3%), but prodromal syndrom was not found in 89.9% of thalamic hemorrhage. 4. The symptoms and neurologic signs on admission in the order of frequency were motor disturbance(98.7%), dysarthria(82.3%), positive Babinski sign(78.5%), headache(69.6%), dizziness(62.0%). hemisensory deficit(48.1%). nausea or vomiting(39.2%), absent or sluggish light reflex(35.4%), changes of consciousness (35.4%), dysphagia (20.3%), voiding difficulty.(13.9%), facial palsy(6.3%), aphasia(3.8%), seizure(38%), 6th N. palsy(3.8%) and small pupil(1.3%). 5. The rate of improvement was found almost equally in the 4th, 5th and 6th decades, but it was shown with dramatic decrease in the over 7th decades. The hospital course had no relationship with the side of hematoma but the level of consciousness had influence upon the prognosis. 6, The small hematoma had better outcome than large in the volume of hematoma under 15cc, but volume of the hematoma had no influence upon the prognosis because the rate of improvement was 75.0% in the volume of hematoma over 15cc. The hospital course had no relationship with ventricular hemorrhage.

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Concentration and Pollution Characteristics of Secondary Aerosol Components Over the Yellow Sea by Ship-Borne Observation in Spring, 2015 (2015년 봄철에 선박으로 관측한 서해상 이차에어로졸 성분의 농도 및 오염 특성)

  • Ko, Hee-Jung;Kang, Chang-Hee;Cha, Joo Wan;Ryoo, Sang-Boom
    • Atmosphere
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    • v.27 no.1
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    • pp.29-40
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    • 2017
  • The $PM_{10}$ and $PM_{2.5}$ particles over the Yellow Sea of Korea were collected by ship-borne observation during two cruises in spring, 2015. Their water-soluble ionic components such as $NH_4^+$, $Na^+$, $K^+$, $Mg^{2+}$, $Ca^{2+}$, $SO_4^{2-}$, $NO_3^-$, $Cl^-$, $F^-$, $CH_3COO^-$, $HCOO^-$, and $CH_3SO_3^-$ were analyzed, in order to examine the pollution characteristics of the secondary aerosol components. The comparative study of particle size distribution has resulted that $NH_4^+$, $nss-SO_4^{2-}$, $nss-Mg2+$, $nss-K^+$, $HCOO^-$, and $CH_3SO_3^-$ species mostly existed in fine particle mode. Meanwhile, nss-F-and sea-salt species were distributed in both fine and coarse particle mode, $NO_3^-$, $nss-Ca^{2+}$, $CH_3COO^-$ species were rich in coarse particle mode. The concentrations of secondary pollutants($nss-SO_4^{2-}$, $NO_3^-$, $NH_4^+$) increased in fine particles, and those of natural components ($nss-Ca^{2+}$, Sea-salt) increased in coarse particles. $NH_4^+$ exists as the form of $(NH_4)_2SO_4$ and $NH_4NO_3$, and mostly as $(NH_4)_2SO_4$ in fine particles. $NH_4NO_3$ has lower content compared to $(NH_4)_2SO_4$, and it mostly existed in fine particles at Yellow Sea I and in coarse particles at Yellow Sea II. The concentration ratios of $NO_3^-/nss-SO_4^{2-}$ for Yellow Sea I and Yellow Sea II were 0.52 and 0.16 in coarse particles, and they were 0.64 and 0.38 in fine particles, respectively, showing that the stationary source emissions were more important than mobile source emissions in Yellow Sea II (except Passage II-4).

Performance of EDLC Electrodes Prepared by Post Treatments of Commercial Activated Carbon (상업용 활성탄의 후처리에 의하여 제조된 전기이중층 커패시터용 전극재의 특성)

  • Wu, Jing-Yu;Hong, Ik-Pyo;Kim, Myung-Soo
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.2
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    • pp.362-370
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    • 2013
  • The coconut shell based activated carbon was applied for EDLC (electric double layer capacitor) electrode with the post treatments. The electrochemical properties were evaluated with a coin cell using the activated carbon as electrode. The initial gravimetric and volumetric capacitance of the coconut shell based activated carbon electrode s were 66 F/g and 39 F/cc, and these values decreased to 54 F/g and 32 F/cc after 100 cycles, respectively showing 82% of charge-discharge efficiency. The properties of CV graph with the commercial activated carbon electrodes showed the serious polarization as the result of additional reaction between electrolyte and impurities of the electrode materials. In order to remove impurities efficiently, the commercial activated carbon was treated by alkali and acid solutions consecutively, and then heat treated to control the pore size distribution and the content of surface functional groups. The surface functional groups decreased with the increased heat temperature and the specific capacitance increased with the decreased surface functional groups. The initial capacitance of coconut shell based activated carbon elec trode which was treated with NaOH and HNO3, and then heat treated at $800^{\circ}C$ was 44 F/cc, and the value turned out to be 42 F/cc after 100 cycles, showing over 95% of charge-discharge efficiency.

A Survey on the Indoor Temperature and Power Consumption of Domestic Refrigerator (가정용 냉장고의 고내온도 및 전력소비 실태조사)

  • Kim, Jong-Ryeol
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.2
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    • pp.357-366
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    • 2018
  • In this study, if the set temperature of the refrigerator differs from the set temperature of the refrigerator, the temperature distribution of food in the refrigerator is estimated by measuring the temperature in the refrigerator and in the refrigerator room. In addition, based on the set temperature of the refrigerator and the freezer, the temperature range of the heat is large and the time required to recover to the set temperature is to be determined. And the optimal setting temperature for home refrigerators is to be shown by measuring the amount of power consumed to recover to the set temperature. As a result, the conditions in which the temperature in the freezer realized $-18^{\circ}C$ were only appropriate in case 3, Case 6, Case 8, and Case 9 when the set temperature in the refrigerator was lower than that in the freezer. Under these conditions, the minimum temperature in the refrigerator was $-1.1^{\circ}C$, Case 6 was $-1.5^{\circ}C$, Case 8 was $-1.1^{\circ}C$ and Case 9 was $-0.8^{\circ}C$, respectively. Also, the total power consumption during the 10 hours operation time of each case was greater than the setting temperature of the freezer and the refrigerator except case 4, since case 4 started operation around 13:30 in the morning.