• Title/Summary/Keyword: Discrete Variable

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A case of childhood relapsing/remitting multiple sclerosis and interferon β-1b treatment in a Korean patient (소아 재발/완화형 다발성 경화증 환자에서 인터페론 베타 1b 치료 1례)

  • Kim, Hyun Seok;Lee, Won Deok;Lee, Jun Hwa;Cho, Kyung Lae
    • Clinical and Experimental Pediatrics
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    • v.50 no.6
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    • pp.580-584
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    • 2007
  • Multiple sclerosis (MS) is a demyelinating disorder that affects discrete areas of the CNS, including the optic nerves, in a quite variable relapsing-remitting fashion over a prolonged period of time. Although MS is usually considered to be a disease that affects peoples in early to middle adulthood, children do develop multiple sclerosis. The frequency of MS onset before the age of 15 years is 2.7-5% of all cases, while MS onset during infancy and early childhood was observed to be 0.2-0.7% of all cases. We report here on a Korean case of a relapsing-remitting MS female child who was treated with four rounds of intravenous methylpredinsolone pulse therapy and preventive Interferon-$\beta$-1b ($Betaferon^{(R)}$).

Parametric modeling and shape optimization design of five extended cylindrical reticulated shells

  • Wu, J.;Lu, X.Y.;Li, S.C.;Xu, Z.H.;Wang, Z.D.;Li, L.P.;Xue, Y.G.
    • Steel and Composite Structures
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    • v.21 no.1
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    • pp.217-247
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    • 2016
  • Five extended cylindrical reticulated shells are proposed by changing distribution rule of diagonal rods based on three fundamental types. Modeling programs for fundamental types and extended types of cylindrical reticulated shell are compiled by using the ANSYS Parametric Design Language (APDL). On this basis, conditional formulas are derived when the grid shape of cylindrical reticulated shells is equilateral triangle. Internal force analysis of cylindrical reticulated shells is carried out. The variation and distribution regularities of maximum displacement and stress are studied. A shape optimization program is proposed by adopting the sequence two-stage algorithm (RDQA) in FORTRAN environment based on the characteristics of cylindrical reticulated shells and the ideas of discrete variable optimization design. Shape optimization is achieved by considering the objective function of the minimum total steel consumption, global and locality constraints. The shape optimization for three fundamental types and five extended types is calculated with the span of 30 m~80 m and rise-span ratio of 1/7~1/3. The variations of the total steel consumption along with the span and rise-span ratio are analyzed with contrast to the results of shape optimization. The optimal combination of main design parameters for five extended cylindrical reticulated shells is investigated. The total steel consumption affected by distribution rule of diagonal rods is discussed. The results show that: (1) Parametric modeling method is simple, efficient and practical, which can quickly generate different types of cylindrical reticulated shells. (2) The mechanical properties of five extended cylindrical reticulated shells are better than their fundamental types. (3) The total steel consumption of cylindrical reticulated shells is optimized to be the least when rise-span ratio is 1/6. (4) The extended type of three-way grid cylindrical reticulated shell should be preferentially adopted in practical engineering. (5) The grid shape of reticulated shells should be designed to equilateral triangle as much as possible because of its reasonable stress and the lowest total steel consumption.

An Efficient Compression Method of Integral Images Using Adaptive Block Modes (적응적인 블록 모드를 이용한 집적 영상의 효율적인 압축 방법)

  • Jeon, Ju-Il;Kang, Hyun-Soo
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.47 no.6
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    • pp.1-9
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    • 2010
  • In this paper, we propose an efficient compression method of the integral images. The integral imaging is a well-known technique to represent and record three-dimensional images. The proposed method is based on three dimensional discrete cosine transform (3D-DCT). The 3D-DCT techniques for the integral images have been reported as an efficient coding method for the integral images which reduces the redundancies between adjacent elemental images. The proposed method is a compression method efficient to integral images using adaptive block mode(ABM), based on the 3D-DCT technique. In the ABM, 3D-DCT blocks adaptive to the characteristics of integral images are constructed, which produces variable block size 3D-DCT blocks, and then 3D-DCTs for the 3D blocks are performed. Experimental results show that the proposed method gives significant improvement in coding efficiency. Especially, at the high bit-rates, the proposed method is more excellent since the overhead incurred by the proposed method take less part of the total bits.

Shape optimization for partial double-layer spherical reticulated shells of pyramidal system

  • Wu, J.;Lu, X.Y.;Li, S.C.;Zhang, D.L.;Xu, Z.H.;Li, L.P.;Xue, Y.G.
    • Structural Engineering and Mechanics
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    • v.55 no.3
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    • pp.555-581
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    • 2015
  • Triangular pyramid and Quadrangular pyramid elements for partial double-layer spherical reticulated shells of pyramidal system are investigated in the present study. Macro programs for six typical partial double-layer spherical reticulated shells of pyramidal system are compiled by using the ANSYS Parametric Design Language (APDL). Internal force analysis of six spherical reticulated shells is carried out. Distribution regularity of the stress and displacement are studied. A shape optimization program is proposed by adopting the sequence two-stage algorithm (RDQA) in FORTRAN environment based on the characteristics of partial double-layer spherical reticulated shells of pyramidal system and the ideas of discrete variable optimization design. Shape optimization is achieved by considering the objective function of the minimum total steel consumption, global and locality constraints. The shape optimization of six spherical reticulated shells is calculated with the span of 30m~120m and rise to span ratio of 1/7~1/3. The variations of the total steel consumption along with the span and rise to span ratio are discussed with contrast to the results of shape optimization. The optimal combination of main design parameters for six spherical reticulated shells is investigated, i.e., the number of the optimal grids. The results show that: (1) The Kiewitt and Geodesic partial double-layer spherical reticulated shells of triangular pyramidal system should be preferentially adopted in large and medium-span structures. The range of rise to span ratio is from 1/6 to 1/5. (2) The Ribbed and Schwedler partial double-layer spherical reticulated shells of quadrangular pyramidal system should be preferentially adopted in small-span structures. The rise to span ratio should be 1/4. (3) Grids of the six spherical reticulated shells can be optimized after shape optimization and the total steel consumption is optimized to be the least.

Organized Hematoma in the Maxillary Sinus (상악동에 발생한 organized hematoma)

  • Kim, Jae-Jin
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.32 no.5
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    • pp.473-477
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    • 2010
  • Organized hematoma of the maxillary sinus is a rare, nonneoplastic benign lesion with locally destructive behavior that may mimic a malignancy. Clinically, symptoms do not usually occur while the lesion remains localized to the maxillary sinus. Because there is gradual enlargement of the lesion causing erosion and displacement of the adjacent bony structures, symptoms such as epistaxis, cheek swelling, nasal obstruc-tion, headache, and exophthalmos become manifest. Radiologically, unilateral cases are much more fre-quent than bilateral, and Waters' view shows complete opacity of the expanded maxillary sinus and some masses. CT scan shows a large heterogeneous enhancing mass causing considerable expansion of the max-illary sinus with bony erosion. On MR imaging, the mass usually has a variable signal intensity on T1- and T2- weighted images, ranging from low to high. After contrast administration, discrete areas of enhance-ment are present within the mass. Although the disease is essentially benign and nonneoplastic, differen-tial diagnosis from neoplastic disease including malignancy both clinically and radiologically has been always problematic. Accurate preoperative diagnosis of organized hematoma of the maxillary sinus is important to avoid unnecessary extensive surgery, because this condition is curative with a simple, conservative surgical approach and rarely recur. Organized hematoma of the maxillary sinus should be included in the differential diagnosis when patients have recurrent epistaxis, slow-growing mass of the cheek, nasal obstruction, and expansile mass in the maxillary sinus. A 33-year-old man was referred to the department of oral and maxillofacial surgery with a three-month history of slowly growing painful swelling of the left cheek. The mass of the maxillary sinus was resected by a Caldwell-Luc approach. Histopahtoly showed only a fibous encapsulated organized hematoma. To our knowledge, organized hematoma of the maxillary sinus has not been previously described in the Korean literature of the oral and maxillofacial surgery. We report a case of organized hematoma of the maxillary sinus presenting with an enlarging maxillary sinus mass.

An application of LAPO: Optimal design of a stand alone hybrid system consisting of WTG/PV/diesel generator/battery

  • Shiva, Navid;Rahiminejad, Abolfazl;Nematollahi, Amin Foroughi;Vahidi, Behrooz
    • Advances in Energy Research
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    • v.7 no.1
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    • pp.67-84
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    • 2020
  • Given the recent surge of interest towards utilization of renewable distributed energy resources (DER), in particular in remote areas, this paper aims at designing an optimal hybrid system in order to supply loads of a village located in Esfarayen, North Khorasan, Iran. This paper illustrates the optimal design procedure of a standalone hybrid system which consists of Wind Turbine Generator (WTG), Photo Voltaic (PV), Diesel-generator, and Battery denoting as the Energy Storage System (ESS). The WTGs and PVs are considered as the main producers since the site's ambient conditions are suitable for such producers. Moreover, batteries are employed to smooth out the variable outputs of these renewable resources. To this end, whenever the available power generation is higher than the demanded amount, the excess energy will be stored in ESS to be injected into the system in the time of insufficient power generation. Since the standalone system is assumed to have no connection to the upstream network, it must be able to supply the loads without any load curtailment. In this regard, a Diesel-Generator can also be integrated to achieve zero loss of load. The optimal hybrid system design problem is a discrete optimization problem that is solved, here, by means of a recently-introduced meta-heuristic optimization algorithm known as Lightning Attachment Procedure Optimization (LAPO). The results are compared to those of some other methods and discussed in detail. The results also show that the total cost of the designed stand-alone system in 25 years is around 92M€ which is much less than the grid-connected system with the total cost of 205M€. In summary, the obtained simulation results demonstrate the effectiveness of the utilized optimization algorithm in finding the best results, and the designed hybrid system in serving the remote loads.

Neurocognitive Function Differentiation from the Effect of Psychopathologic Symptoms in the Disability Evaluation of Patients with Mild Traumatic Brain Injury

  • Kim, Jin-Sung;Kim, Oh-Lyong;Koo, Bon-Hoon;Kim, Min-Su;Kim, Soon-Sub;Cheon, Eun-Jin
    • Journal of Korean Neurosurgical Society
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    • v.54 no.5
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    • pp.390-398
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    • 2013
  • Objective : We determined whether the relationship between the neuropsychological performance of patients with mild traumatic brain injury (TBI) and their psychopathological characteristics measured by disability evaluation are interrelated. In addition, we assessed which psychopathological variable was most influential on neuropsychological performance via statistical clustering of the same characteristics of mild TBI. Methods : A total of 219 disability evaluation participants with mild brain injury were selected. All participants were classified into three groups, based on their psychopathological characteristics, via a two-step cluster analysis using validity and clinical scales from the Minnesota Multiphasic Personality Inventory (MMPI) and Symptom Checklist-90-revised (SCL-90-R). The Korean Wechsler Adult Intelligence Scale (K-WAIS), Korean Memory Assessment Scale (K-MAS) and the Korean Boston Naming Test (K-BNT) were used to evaluate the neurocognitive functions of mild TBI patients. Results : Over a quarter (26.9%) experienced severe psychopathological symptoms and 43.4% experienced mild or moderate psychopathological symptoms, and all of the mild TBI patients showed a significant relationship between neurocognitive functions and subjective and/or objective psychopathic symptoms, but the degree of this relationship was moderate. Variances of neurocognitive function were explained by neurotic and psychotic symptoms, but the role of these factors were different to each other and participants did not show intelligence and other cognitive domain decrement except for global memory abilities compared to the non-psychopathology group. Conclusion : Certain patients with mild TBI showed psychopathological symptoms, but these were not directly related to cognitive decrement. Psychopathology and cognitive decrement are discrete aspects in patients with mild TBI. Furthermore, the neurotic symptoms of mild TBI patients made positive complements to decrements or impairments of neurocognitive functions, but the psychotic symptoms had a negative effect on neurocognitive functions.

Modeling on Structural Control of a Laminated Composite Plate with Piezoelectric Sensor/Actuators (압전재료를 이용한 복합적층판의 구조제어에 관한 모델링)

  • 황우석;황운봉;한경섭;박현철
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.1
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    • pp.90-100
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    • 1993
  • A finite element formulation of vibration control of a laminated plate with piezoelectric sensor/ actuators is presented. Classical lamination theory with the induced strain actuation and Hamilton's principle are used to formulate the equations of motion of the system. The total charge developed on the sensor layer is calculated from the direct piezoelectric equation. The equations of motion and the total charge are discretized with 4 node, 12 degrees of freedom quadrilateral plate bending elements with one electrical degree of freedom. The mass and stiffness of the piezoelectric layer are introduced by treating them as another layer in laminated plate. Piezoelectric sensor/actuators are distributed, but discrete due to the geometry of electrodes. By defining an i.d. number of electrode for each element, modelling of electrodes with variable geometry can be achieved. The static response of a piezoelectric bimorph beam to electrical loading and sensor voltage to given displacement are calculated. For a laminated plate under the negative velocity feedback control, the direct time response by the Newmark-.betha. method and damped frequencies and modal damping ratios by modal state space analysis are derived.

Wavelet Analysis of Visualized Image (가시화 영상의 웨이브렛 해석)

  • Park, Young-Sik;Kim, Okug-Gyu
    • Journal of the Institute of Convergence Signal Processing
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    • v.8 no.3
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    • pp.143-148
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    • 2007
  • The many studies have been proceeding to express accurately the feature of a sudden signal and a uncertain system in the image processing field. It is well know that Fourier Transform is widely used for frequency analysis of any signal. However, The frequency transform domain is not used for expressing the sudden signal change and non-stationary signal at the time-axis by this method. This paper describes of image analysis by discrete wavelet transform. Wavelet modulus maxima on transformed plane gives the Lipschitz exponent expression, which is useful to examine the characteristics of signal or the edge of an image. It is possible to reconstruct the original image only using the few maxima points. The fractal analysis is applied as an examples. The visualized image of oil flow on a ship model is analyzed. The fractal variable is obtained by the maxima analysis and the good results on the exprement is obtained by the visualized image analysis.

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Study on Image Distortions and Bit-rate Changes Induced by Watermark based-on $4{\times}4$ DCT of H.264/AVC (H.264/AVC의 $4{\times}4$ DCT기반 워터마크에 따른 영상왜곡과 비트율 변화에 대한 연구)

  • Kim, Sung-Min;Won, Chee-Sun
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.5 s.305
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    • pp.115-122
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    • 2005
  • There are some problems in directly applying the conventional MPEG bit-stream based watermarking schemes to the bit-stream of a new compression standard, H.264/AVC. In this paper we analyze the effects of the conventional DCT-based watermarking scheme to H.264/AVC, especially in terms of image distortions and bit-rate changes. It turns out that the intra-frame prediction md CAVLC of H.264/AVC with the watermarking worsen the image distortions and bit-rate changes. The experiment results show on average 28.17dB decrease in PSNR and 56.71% increase in bit-rate over all QPs.