• Title/Summary/Keyword: Differentiated Characteristics

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NgR1 Expressed in P19 Embryonal Carcinoma Cells Differentiated by Retinoic Acid Can Activate STAT3

  • Lee, Su In;Yun, Jieun;Baek, Ji-Young;Jeong, Yun-Ji;Kim, Jin-Ah;Kang, Jong Soon;Park, Sun Hong;Kim, Sang Kyum;Park, Song-Kyu
    • The Korean Journal of Physiology and Pharmacology
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    • v.19 no.2
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    • pp.105-109
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    • 2015
  • NgR1, a Nogo receptor, is involved in inhibition of neurite outgrowth and axonal regeneration and regulation of synaptic plasticity. P19 embryonal carcinoma cells were induced to differentiate into neuron-like cells using all trans-retinoic acid and the presence and/or function of cellular molecules, such as NgR1, NMDA receptors and STAT3, were examined. Neuronally differentiated P19 cells expressed the mRNA and protein of NgR1, which could stimulate the phosphorylation of STAT3 when activated by Nogo-P4 peptide, an active segment of Nogo-66. During the whole period of differentiation, mRNAs of all of the NMDA receptor subtypes tested (NR1, NR2A-2D) were consistently expressed, which meant that neuronally differentiated P19 cells maintained some characteristics of neurons, especially central nervous system neurons. Our results suggests that neuronally differentiated P19 cells expressing NgR1 may be an efficient and convenient in vitro model for studying the molecular mechanism of cellular events that involve NgR1 and its binding partners, and for screening compounds that activate or inhibit NgR1.

Profiles of Epstein-Barr Virus Associated Gastric Carcinomas in Brunei Darussalam

  • Yen, Rachel Lai Siaw;Telisinghe, Pemasari Upali;Cunningham, Anne;Abdullah, Muhd Syafiq;Chong, Chee Fui;Chong, Vui Heng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10489-10493
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    • 2015
  • Background: Gastric cancer is the second most common gastrointestinal cancer and is largely attributed to Helicobacter pylori (H. pylori) infection. In addition, studies have also shown association with Epstein-Barr virus (EBV) in 10% of gastric cancers. This study assessed the characteristics of EBV associated gastric cancers (EBVaGC) in Brunei Darussalam. Materials and Methods: This study included gastric cancers diagnosed between 2008 and 2012, registered with the Department of Pathology RIPAS Hospital, Brunei Darussalam. Clinical case notes were systematically reviewed. Histology specimens were all stained for EBV and also assessed for intestinal metaplasia and H. pylori. Results: There were a total of 81 patients (54 male and 27 females) with a mean age of $65.8{\pm}14.8years$ included in the study. Intestinal metaplasia and active H. pylori infection were detected in 40.7% and 30.9% respectively. A majority of the tumors were proximally located (55.6%), most poorly differentiated (well differentiated 16%, moderately differentiated 30.9% and poorly differentiated 53.1%) and the stages at diagnosis were; stage I (44.4%), stage II (23.5%), stage III (8.6%) and stage IV (23.5%). EBV positivity (EBVaGC) was seen in 30.9%. Between EBVaGC and EBV negative gastric cancers, there were no significant differences (age, gender, ethnic group, presence of Intestinal metaplasia, tumor locations, stages of disease and degree of tumor differentiation). Conclusions: This study showed that a third of gastric cancers in Brunei Darussalam were positive for EBV, higher than what have been reported in the literature. However, there were no significant differences between EBVaGC and EBV negative gastric cancers. This suggests that the role of EBV in gastric cancer may be mostly incidental rather than any causal relation. However, further studies are required.

Differentiation of the Plutonic Rocks in Saengcho-myon, Sancheong-gun:Trace Element Modelling for the Magmatic Differentiation (산청군 생초면 일대에 분포한 심성암체의 분화에 관한 연구:마그마분화의 미량원소 모델링)

  • 정지곤;김원사;서병민
    • Journal of the Mineralogical Society of Korea
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    • v.4 no.2
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    • pp.69-89
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    • 1991
  • The anorthositic rocks and the many other plutons which are of different varieties and age were distributed in the northern extremity of the distributed areas of H-S anorthositic rocks. The purpose of this study was to find plutons which had comagmatic relationships, and to make clear the magmatic process of anorthositic magma. The plutons were classified, and the petrological and the geochemical characteristics of the plutons were compared and researched in this study. And, because, like anorthosite, the rocks which intrude in the deep crust accompany assimilation, an AFC model calculation was performed to make the differentiation process of the anorthositic rocks clear. The plutons in this area were classified into three groups, and the three groups were composed of the Precambrian anorthositic rocks and related rocks, the Jurassic gabbro, and the plutons of undnown age. The anorthositic magma was differentiated from the anorthositic rocks through the tonalite to the alkali-feldspar granite, and it was differentiated under K, Mg, Fe free/lack condition. It was found from the result of AFC model that the anorthositic rocks were differentiated by fractional crystallization, but they were assimilated with wall-rocks, and the assimilation was performed at the rate of r$\leq$0.1. The plutons which intruded the anorthositic rocks subsequently consisted of the gabbro, the megacrystic granite, the fine-grained granite, and the gneissose granite. But they were formed by the repeated intrusion of magma, which may, or may not, be of the same origin. According to the result of the RCF model, these plutons were differentiated by simple fractional crystallization, and they were assimilated relatively less than the anorthositic rocks.

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A Study on the Architectural Characteristics of Homigot Lighthouse(Cape Clonard) in Pohang (포항 호미곶등대의 건축 특성에 관한 연구)

  • Kim, Jong-Hun
    • Journal of architectural history
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    • v.32 no.3
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    • pp.63-76
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    • 2023
  • Homogot Lighthouse is located in Pohang of the easternmost of Korean Peninsula. Homogot has become first known as Cape Clonard in the West through the navigation log by La Perouse, a Frenchman who embarked on a global exploration in 1785. Homogot Lighthouse represents an outstanding accomplishment of modernization that numerous civilized countries scrambled to attain in the early 20th century. Located where the geographical risk of earthquakes is high, the structure was nonetheless built to be 26.4m high with brick masonry. Structurally safe and aesthetically graceful, it demonstrates neoclassical ideas superbly in terms of style as well. Although the history of Asian lighthouses is shorter than that of European ones. Homogot Lighthouse, which demonstrates the history of a modern lighthouse along with those in Japan and China, is differentiated by the following characteristics. ① The 'living lighthouse heritage' is linked to one of the largest lighthouse museum in the world. ② Where you can see the earliest sunrise at the easternmost of the Eurasian Continent. ③ The completion of a modern-style lighthouse constructed at the easternmost of the Far East after being initiated in Europe. ④ Differentiated historical, architectural, and aesthetic value. ⑤ The heart of the national marine park.

An Efficient Priority Based Adaptive QoS Traffic Control Scheme for Wireless Access Networks

  • Kang Moon-sik
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.9A
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    • pp.762-771
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    • 2005
  • In this paper, an efficient Adaptive quality-of-service (QoS) traffic control scheme with priority scheduling is proposed for the multimedia traffic transmission over wireless access networks. The objective of the proposed adaptive QoS control (AQC) scheme is to realize end-to-end QoS, to be scalable without the excess signaling process, and to adapt dynamically to the network traffic state according to traffic flow characteristics. Here, the reservation scheme can be used over the wireless access network in order to get the per-flow guarantees necessary for implementation of some kinds of multimedia applications. The AQC model is based on both differentiated service model with different lier hop behaviors and priority scheduling one. It consists of several various routers, access points, and bandwidth broker and adopts the IEEE 802.1 le wireless radio technique for wireless access interface. The AQC scheme includes queue management and packet scheduler to transmit class-based packets with different per hop behaviors (PHBs). Simulation results demonstrate effectiveness of the proposed AQC scheme.

The Fine Structure of Callus Derived from Panax ginseng Leaves (인삼의 잎에서 유기된 Callus의 미세구조)

  • 박홍덕
    • Journal of Plant Biology
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    • v.19 no.4
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    • pp.100-106
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    • 1976
  • The fine structure of the callus induced from epidermis of Panax ginseng leaves cultured on Murashige & Skoog medium plus kinetin 0.1mg/l, NAA 0.2mg/l and 2.4-D 0.5mg/l was observed. The cells composing callus tissue are mononucleus. Three types of cells were identified; cells with abundant cytoplasm, cells with relatively differentiated vacuoles and with numerous starch grains in the plastids and ones with highly differentiated vacuoles and with unsaturated lipid granules. Prolamellar body, plastid lamellae, plastid globules, stromacenter, fine tubules, crystal-containing body and DNA-like structures were observed in the stroma of the plastids. The chromoplasts were identified in some cells believed as the mother cells of secretory cells in secretory ducts. Curved or straight micro-fibrils of 100~150A in diameter were observed in the cytoplasm. And the characteristics of cell organelles and cell inclusions and the vacuole formation in callus tissues were discussed.

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A Study on the Real Wearing Condition and Preference of Hair Shop Uniform (헤어샵 종사자의 유니폼 착용실태 및 선호도에 관한 연구)

  • Cha, Sujoung
    • Journal of Fashion Business
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    • v.19 no.4
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    • pp.75-91
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    • 2015
  • There is an increased interest in having beauty regardless of ages and sex with improvement of the national income level and increase in social activities. Competition within the beauty service industry is increasing rapidly because of global impact within Korea wave. Thus, active public relations and offering distinguished service in the beauty service industry are important. Also, uniforms play an important role in providing an image differentiated from other brands and presents professionalism to the customer. Therefore, we determined function and design of uniforms required in beauty service industry by researching wearing realities, satisfaction, preferred designs and functions of uniforms from hair shop staff. Functional and aesthetic uniforms play an important role to enhance the staffs' sense of belonging. In addition, it is good for the image of hair shop. Special design mirroring job characteristics with expression of differentiated personalities is needed. However, the research was conducted only in the hair shop in Seoul, Daejeon, and Gyeonggi-do. Further studies on much wider areas will be needed.

Design and Implementation of Traffic Control System in Differentiated Services Networks (DiffServ 네트워크에서 QoS 보장형 트래픽 제어 시스템 설계 및 구현)

  • 이명섭;김환섭;류명춘;박창현
    • Proceedings of the IEEK Conference
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    • 2002.06a
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    • pp.49-52
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    • 2002
  • QoS support for the Internet traffic becomes an important future requirement of various network devices such as routers and switches. Differentiated Services(Diffserv) is considered as an efficient feasible solution for providing different service characteristics to different classes of network users. IETF Diffserv working group has already defined a general architecture of Diffserv and is extending its detail features. Network vendors also start implementing Diffserv enabled network devices. However, the management of Diffserv is not fully standardized yet. This paper, we present methods of traffic flow control in Diffserv Networks. we have designed a Diffserv Traffic Control system.

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Early Ontogeny of Vascular Cambium in Cotyledonary Node of Seedlings in Pinus koraiensis S. et Z. (잣나무(Pinus koraiensis S. et Z.) 유식물의 자엽절에서 유관속 형성층의 초기 발생)

  • 홍성식
    • Journal of Plant Biology
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    • v.36 no.1
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    • pp.29-34
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    • 1993
  • Observation was made on early ontogeny of vascular cambium in the cotyledonary node of Pinus koraiensis seedling in order to clarify the cambial ontogeny of the node which was hardly elongated. In transverse view, the derivatives by the early periclinal divisions at the outer region of the procambial strands differentiated to protophloem with establishing a certain degree of radial seriations. Later, some cells in the central region of the procambial strands begin divide periclinally, eventually the cells, differentiate gradually to the vascular cambium. In tangential view, early procambium is consisted of homogeneous short cells with transverse end walls which are tansformed into the long cells and short cells gradually. The long cells continue intrusive growth and the short cells repeat transverse division. Finally, the long and short cells differentiated to cambial fusiform initials and ray initials respectively. In tangential section, the differentiation pattern of cambial initials resembles that of the stem of Ginkgo biloba. But in transverse view, the characteristics in the origin of vascular cambium of the cotyledonary node resembles that of root. The vascular cambium in cotyledonary node is completed after eleven prophylls were formed.

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