• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.1147-1150
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• 2013

Background: Cancer diagnostic biomarkers have a wide range of applications that include early detection of oral precancerous lesions and oral squamous cell carcinomas, and assessing the metastatic status of lesions. The interferon stimulated ISG15 gene encodes an ubiquitin-like protein, which conjugates to stabilize activation status of associated proteins. Hence a deregulated expression of ISG15 may promote carcinogenesis. Indeed overexpression of ISG15 has been observed in several cancers and hence it has been proposed as a strong candidate cancer diagnostic biomarker. Given the emerging relationship between malignant transformation and ISG15, we sought to examine the expression pattern of this gene in tumor biopsies of oral squamous cell carcinoma (OSCC) tissues collected from Indian patients. Materials and Methods: Total RNA isolated from thirty oral squamous cell carcinoma tissue biopsy samples were subjected to semi-quantitative RT-PCR with ISG15 specific primers to elucidate the expression level. Results: Of the thirty oral squamous cell carcinomas that were analyzed, ISG15 expression was found in twenty four samples (80%). Twelve samples expressed low level of ISG15, six of them expressed moderately, while the rest of them expressed very high level of ISG15. Conclusions: To the best of our knowledge, the results show for the first time an overexpression of ISG15 in up to 80% of oral squamous cell carcinoma tissues collected from Indian patients. Hence ISG15 may be explored for the possibility of use as a high confidence diagnostic biomarker in oral cancers.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2008년 영문 학술대회
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• pp.187-194
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• 2008

Because the types and severities of most engine faults are various and complex, it is not easy that the conventional model based fault detection approach like the GPA(Gas Path Analysis) method can monitor all engine fault conditions. Therefore this study proposed newly a diagnostic algorithm for isolating and diagnosing effectively the faulted components of the smart UAV propulsion system, which has been developed by KARI(Korea Aerospace Research Institute), using the fuzzy logic and the neural network algorithms. A precise performance model should be needed to perform the model-based diagnostics. The based engine performance model was developed using SIMULINK. For the work and mass flow matching between components of the steady-state simulation, the state-flow library was applied. The proposed steady-state performance model can simulate off-design point performance at various flight conditions and part loads, and in order to evaluate the steady-state performance model their simulation results were compared with manufacturer's performance deck data. According to comparison results, it was confirm that the steady-state model well agreed with the deck data within 3% in all flight envelop. The diagnosis procedure of the proposed diagnostic system has the following steps. Firstly after obtaining database of fault patterns through performance simulation, then secondly the diagnostic system was trained by the FFBP networks. Thirdly after analyzing the trend of the measuring parameters due to fault patterns, then fourthly faulted components were isolated using the fuzzy logic. Finally magnitudes of the detected faults were obtained by the trained neural networks. Because the detected faults have almost same as degradation values of the implanted fault pattern, it was confirmed that the proposed diagnostic system can detect well the engine faults.

• 대한한방내과학회지
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• 제30권4호
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• pp.813-820
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• 2009

Background : Static blood is a kind of etiological factor including stagnated blood and blood overflowed out of the vessels. It is one of the causes of stroke in oriental medicine. Objectives : The purpose of this study was to evaluate the static blood pattern and its indicators in stroke pattern diagnosis. Methods : For the standardization of pattern diagnosis in stroke, we set 5 patterns (Fire-heat, Dampness-phlegm, Static blood, Qi deficiency, Yin deficiency) and developed 61 indicators. Patients with a first-ever stroke, within 1 month after the onset of stroke. Two physicians checked the indicators independently. They then performed pattern diagnosis and rechecked the indicators which were referred to pattern diagnosis. If pattern identifications were diagnosed the same, it would confirm pattern identification. We examined the frequency of all indicators and referred indicators in static blood pattern patients. Results : In 859 patients, static blood pattern was shared by 24(2.8%). The indicators which affect static blood pattern were mainly rough pulse and bluish purple tongue, other indicators were not major effectors. Conclusion : This result shows that it is inconsistent to set up static blood pattern as a major pattern in stroke. Nevertheless, static blood is still a valuable concept in the clinical field. Other study methods will be required to establish the pattern diagnostic indicators for static blood pattern.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 C
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• pp.1685-1687
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• 2002

High voltage(H.V.) induction motors have been applied to various industrial applications. But aging and failure of induction motors are initiated by electrical, mechanical, thermal and chemical processes during manufacturing or in-service. These detects reduce locally the dielectric strength of the insulation. At such defects partial discharges can occur, which cause further degradation of the insulation and reduce the life time of the H.V induction motors. Consequently in this paper, we studied the partial discharge pattern analysis of H.V. induction motor for on-site applications.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2005년도 한국컴퓨터종합학술대회 논문집 Vol.32 No.1 (B)
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• pp.874-876
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• 2005

간경변을 보유한 환자의 복부 CT 영상을 관찰한 결과 비장의 웨이브 패턴(wave pattern)이 정상간을 보유한 사람의 복부 CT 영상과 차이가 있음이 발견되었다. 한편 간경변에 동반된 비장은 일반적으로 비대한 것으로 알려져 있다. 따라서 본 논문에서는 이러한 두가지 원리를 바탕으로, 복부 CT 영상에서 비장의 웨이브 패턴을 이용하여 비장 비대를 효과적으로 진단하는 새로운 방법을 제시한다. 제안된 방법에서는 단순히 비장의 크기만물 이용하지 않고 비장의 형태 변화를 바탕으로 국소적 비장 비대의 자동 판정을 효과적으로 수행할 수 있음을 입증하였다.

• 동의생리병리학회지
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• 제20권2호
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• pp.482-487
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• 2006

The identification of the exterior-interior pattern and the cold-heat pattern is one of the most frequently used diagnostic methods in Oriental medicine. No systematic studies, however, have yet been conducted to determine the emotional and autonomic factors involved in the exterior-interior and cold-heat. In this study, the relationships between depression, anxiety, and the exterior-interior and cold-heat patterns in 100 healthy female volunteers with a mean age of 42.77 were also investigated. The autonomic nervous system's control of human temperature is a well known fact. Thus, this paper also aimed to investigate the correlationof the autonomic nervous system and patterns of the exterior-interior and cold-heat. The analysis of heart rate variability (HRV), which has become a popular non-invasive tool for assessing the activities of the autonomic nervous system, was conducted in this study. No relationship was found between the exterior-interior and cold-heat pattern scores and the degree-of-depression scores. But there was a significant difference between the exterior-interior and cold-heat pattern scores of the different anxiety types, and between those of the different anxiety levels. The depression and anxiety levels also had an effect on the HRV indices.

• 대한한의학원전학회지
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• 제37권1호
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• pp.57-75
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• 2024

Objectives : The objective of this paper is to study the literature on stagnation pattern, to further determine reasoning for the emphasis on Liver-qi stagnation out of all the Five Zang stagnation patterns. Methods : Stagnation patterns in literature from the Xian-Qin/Liang-Han period, Sui-Tang-Song period, Jin-Yuan period and Ming-Qing period were studied and analyzed. Results & Conclusions : Based on chronological analysis on discussions of stagnation pattern, the Five stagnation in the Neijing were related to the excessiveness and deficiency of the Five circuits. After the discussions of the Four Masters of the Jin-Yuan period, WangAndao explained that stagnation could happen without relation to external contraction in his discussion of Benqiziyubing. Yutuan focused on the inter-relationship between the six stagnation patterns, emphasizing qi stagnation, while Sunyikui discussed stagnation pattern within the framework of the Five Zang stagnation. Zhaoxianke argued for the first time that one of the treatment methods of Wood stagnation could replace the five treatment methods, focusing on Wood stagnation which could be the clue to stagnation pattern. Of current Zangfu diagnostic terminology, the influential Liver qi stagnation remains to this day.

• Journal of Oral Medicine and Pain
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• 제44권4호
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• pp.169-173
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• 2019

Purpose: To determine whether the morphological features of the palatal rugae are associated with sex and age in children and adolescents. Methods: A total of 300 diagnostic models of the palatal rugae of children and adolescents were collected. The models were classified into male and female and<13- and ≥13-year-old groups. The palatal rugae pattern, and the number and length of palatal rugae plicae, were analyzed. Results: The number of palatal rugae plicae was higher in females than in males, however, the difference was negligible. In the group aged 13 years or more, the number was higher in the male group on the left side. There was no association between the number of palatal rugae plicae and age group. The type I pattern was the most common in both males and females. The length of palatal rugae plicae was greater in males than in females. There was no association between the length of palatal rugae plicae and age group. Conclusions: The number and length of palatal rugae were associated with sex, but the morphological features of the palatal rugae could not distinguish between children and adolescents. These findings suggest that the palatal rugae have limited value for identification of individuals.

• 대한안전경영과학회지
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• 제22권1호
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• pp.15-21
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• 2020

Industrial Motors diagnostic equipment is highly dependent on the automation system, so if there are defects in the automation equipment, it can only rely on the operator's intuitive judgment.To help with intuitive judgment, Park's Vactor Approach(PVA) represents the current signal as a pattern of circles, so it can tell if a fault occurs when the circle is distorted. However, the failure to judge the degree of distortion of the circle pattern is the basis of the fault, so it will face difficulties. In this paper, in order to compare the faults of PVA, the period of d-axis current of PVA pulsation was mastered, so that two phase differences occurred in the same signal source. Through experiments, it is confirmed that this is a 90 degree cross formation of PVA, which is convenient for judging from the vision that there is no fault, thus helping the operator to make intuitive judgment.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 1998년도 학술발표회 논문집
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• pp.632-637
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• 1998

The purpose of this study of this study is to find tide and tidal current variation by three dimensional numerical model of tide and tidal current in the bay of Cheonsu in Korea. On the basis of the observed data on water temperature and salinity data and wind data of summer(July) in the bay of Cheonsu in Korea, water circulation in the bay of Cheonsu is investigated with use of a robust diagnostic numerical model, including calculated co-range and co-tidal charts of M2 tide are similar to the observed ones. The residual flow Pattern at the surface layer during summer formed clockwise circulation in the front coastal the dike of the Sosam A zone(Ganwor island) and Taeju island. The residual flow pattern at the 15m layer during formed clockwise circulation in the front Taeju island. The residual flow Pattern at the surface layer formed anti-clockwise circulation in the upper Sangmok and Naepasu island.