Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Relationships between depression, anxiety, 'exterior-interior pattern and cold-heat pattern' and Heart Rate Variability in healthy Subjects

건강인의 표리 한열 변증, HRV, 우울, 불안 지표의 상관성 분석

  • Kim, Ji-Eun (Department of Biomedical Engineering, Kyunghee University) ;
  • Lee, Jeong-Chan (Department of Biomedical Engineering, Kyunghee University) ;
  • Kang, Hee-Chul (Department of Neuropsychiatry, School of Oriental Medicine, Sangji University) ;
  • Lee, Seung-Gi (Department of Neuropsychiatry, School of Oriental Medicine, Sangji University) ;
  • Park, Kyung-Mo (Department of Biomedical Engineering, Kyunghee University)
  • 김지은 (경희대학교 동서의료공학과) ;
  • 이정찬 (경희대학교 동서의료공학과) ;
  • 강희철 (상지대학교 한의과대학 한방신경정신과) ;
  • 이승기 (상지대학교 한의과대학 한방신경정신과) ;
  • 박경모 (경희대학교 동서의료공학과)
  • Published : 2006.04.25
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Abstract

The identification of the exterior-interior pattern and the cold-heat pattern is one of the most frequently used diagnostic methods in Oriental medicine. No systematic studies, however, have yet been conducted to determine the emotional and autonomic factors involved in the exterior-interior and cold-heat. In this study, the relationships between depression, anxiety, and the exterior-interior and cold-heat patterns in 100 healthy female volunteers with a mean age of 42.77 were also investigated. The autonomic nervous system's control of human temperature is a well known fact. Thus, this paper also aimed to investigate the correlationof the autonomic nervous system and patterns of the exterior-interior and cold-heat. The analysis of heart rate variability (HRV), which has become a popular non-invasive tool for assessing the activities of the autonomic nervous system, was conducted in this study. No relationship was found between the exterior-interior and cold-heat pattern scores and the degree-of-depression scores. But there was a significant difference between the exterior-interior and cold-heat pattern scores of the different anxiety types, and between those of the different anxiety levels. The depression and anxiety levels also had an effect on the HRV indices.

Keywords

References

  1. Ramaekers, D., Ector, H., Aubert, A.E., Rubens, A., van de Werf, F. Heart rate variability and heart rate in healthy volunteers : Is the female autonomous nervous system cardioprotective? Eur Heart J. 19:1334-1341, 1988 https://doi.org/10.1053/euhj.1998.1084
  2. Karl-jurgen, Bar, Wolf, Greiner, Thomas, jochum. The influence of major depression and its treatment on heart rate variability and pupillary light reflex parameters. Journal of affective disorders. 82:245-252, 2004 https://doi.org/10.1016/j.jad.2003.12.016
  3. 김완희, 한의학적 한열발생기전. 대한한의진단학회지, 4(1):19-31, 2000
  4. 정현영, 영추-한열에 대한 연구, 대한한의진단학회지, 2(2):121
  5. 남봉현. 건강수준 측정도구 SF-36의 타당성 평가. 서울대학교 대학원. 23-25, 2003
  6. 이수헌, 한성수, 장은수, 김종열. 사상체질별 한열 특성에 대한 임상 연구. 동의생리병리 학회지. 19(3):811-814, 2005
  7. 고려대학교 부설 행동과학 연구소. 심리척도 핸드북(I). 3판. 서울: 학지사. 464-466, 419-424, 2000
  8. Pomeranz, B., Macaulay, R., Caudill, M., Kutz, I., Adam, D., Gordon, D, et al. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol 248: H151-153, 1985
  9. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulatioin. 93(5):1043-1065, 1996 https://doi.org/10.1161/01.CIR.93.5.1043
  10. Ronald, D., Begger, Solange Akselrod, An Efficient Algorithm for Spectral Analysis of Heart Rate Variability, IEEE Transctions on Biomedical engineering, BME(9):900-904, 1986 https://doi.org/10.1109/TBME.1986.325789
  11. Rajendra Acharya, Y., Kannathal, N., Ong Wai Sing, Luk Yi Ping and TjiLeng Chua. Heart rate analysis in normal subjects of various age groups. BioMedical Engineering Online 3:24, 2004 https://doi.org/10.1186/1475-925X-3-24
  12. 남동현. 연령별 맥박변이도 표준화에 관한 연구. 경희대학교 대학원 석사학위논문. 2002
  13. Galetta, F., Franzoni, F., Femia, F.R., Prattichizzo, F, Responses to Tilt test in young and elderly patients with syncope of unknown origin. Biomed Pharmacother. Oct;58(8):443-446, 2004 https://doi.org/10.1016/j.biopha.2004.08.007
  14. Davidson, J., Watkins, L. Effects of paroxetine and venlafaxine XR on heart rate variability in depression. J Clin Psychopharmacol. Oct;25(5):480-484, 2005 https://doi.org/10.1097/01.jcp.0000177547.28961.03
  15. Carney, R.M., Blumenthal, J.A. Low heart rate variability and the effect of depression on post-myocardial infarction mortality., Arch Intern Med. Jul 11;165(13):1486-1491, 2005 https://doi.org/10.1001/archinte.165.13.1486