• Journal of the Korean BIBLIA Society for library and Information Science
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• v.21 no.4
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• pp.179-192
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• 2010

This study presents "The Subject List for Developmental Bibliotherapy", for the purpose of offering selfdevelopment information to university students to assist them in identifying problems, and solving them while strengthening their egos. Theories relating to developmental psychology of young adult, results of analysing of student survey and successful examples of bibliotherapy subject lists from other universities have been applied for classifying of subject of this study. The four classes, are physical/mental development, social/emotional development, cognitive development and career development, have been classified into sub-classes and divisions in this study. With fixed career goals based on documents of developmental bibliotherapy, students can manage a more effective university education as early as their freshman year.

• Child Health Nursing Research
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• v.12 no.2
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• pp.260-267
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• 2006

Purpose: This pilot study was to develop Korean version of CDI(The Child Development Inventory) and assess the validation and reliability on K-CDI. Method: The K-CDI is assessed by parent-report method that has designed to screen children developmental functioning on 12 months to 6.5 years of age /or older children who are judged to be functioning in the one to six-year range. The inventory assesses areas of child development in the social, self-help, motor, language, letter and number skills. also, it includes various symptoms and behavior problems that young children may have. Participants were 130 children and their mothers who has lived in Seoul or Gyounggi-Do. Data was analyzed on the ratio of item response, Pearson's correlation, and Cronbach alpha. Results: 270 items with 8 sub-developmental realms were confirmed the reliabilities and validity on Korean children. Total 300 items were selected for restandardization. There was a significant correlation between the score of Social Maturity Scale and K-CDI. The corrlation coefficient alpha was .98. Conclusion: This study indicated that CDI is applicable in the clinical and early childhood educational setting for developmental assessment in Korea.

• The Journal of Korean Academy of Sensory Integration
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• v.18 no.1
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• pp.1-12
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• 2020

Objective : In this study, we are going to check the impact of the daily performance of a child with developmental disabilities on the parent's burden and quality of life. Methods : 120 parents of children with developmental disabilities were targeted in Chungcheong and Jeolla provinces. To measure the daily performance ability of children with developmental disabilities, we used evaluative Pediatric Evaluation of Disability Inventory and The burden of parents was measured by Family Burden Questionnaire and the quality of life by Beach Center Family Quality of Life Scale. Based on the data collected, independent t-test, one-way anova, Pearson correlation analysis and regression analysis were conducted to check the impact of a child's daily performance ability of developmental disability on the parent's burden and quality of life. Results : The daily performance ability of a children with developmental disabilities showed a negative correlation with the burden of the parents and a positive correlation with the quality of life. The hygiene and bowel & bladder control of children with developmental disabilities had an important influence on parent's burden, while hygiene, toileting, and bowel & bladder control of children with developmental disabilities had a significant effect on their parent's quality of life. Conclusion : It has been shown that the daily performance ability of a children with developmental disabilities has a major influence on parent's burden and quality of life. In order to reduce the burden and improve quality of life, therapeutic intervention, education and interview programs for daily life of children with developmental disabilities need to be carried out systematically by occupational therapists.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1749-1752
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• 2012

Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2003.10a
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• pp.57-69
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• 2003

It is well known that many pesticides possess hormonal activity, and affect the developments of wildlife and mammals including human. Currently, pyrethroid insecticides are in worldwide use to control in and outdoor pests, providing potential far environmental exposure. Hormonal activities of these pyrethroid insecticides, however, have been little studied, and the developmental effects of them were no reported. Therefore, we firstly examined the potential estrogenic activities of some pyrethroid insecticides (permethrin, cypermethrin, tetramethrin, deltamethrin, sumithrin, fenvalerate and bioallethrin) by immature rat uterotrophic assay, luciferase reporter gene assay and Calbindin-D$\sub$9k/ (CaBP-9k) gene expression assay. Uterine wet weights were increased by permethrin and the permethrin-induced weights were inhibited by ICI 182780 in the uterolrophic assay. On the other hand tetramethrin significantly reduced uterine and vaginal wet weights, and also inhibited the E2-induced weight increases at all doses tested. Cypermethrin and sumithrin had a tendency to increase uterine weights, although not statistically significant. Permethrin and cypermethrin dose-dependently increased the luciferase activity in reporter gene assay. Northern blot analysis showed that permethrin induced CaBP-9k mRNA expression whereas tetramethrin inhibted. Subsequent studies were conducted to investigate the possible developmental effects of four pyrethroid insecricides (permethrin, cypermethrin, sumithrin and teramethrin). Either diethlbestrol (DES) or 17${\beta}$ -estradiol (E2) was used as a reference control in this study. Pyrethroid insecticides were administered to Sprague Dawley rats via subcutaneous injection at 6 to 18 days of gestation or 1 to 5 days after birth. In utero treatment of permethrin (10mg/kg/day) in female rat resulted in significant increases in uterine and ovarian weights while significant decreases in serum E2 concentration, uterine and ovarian ER${\alpha}$ mRNA levels. Sumithrin and permethrin led to acceleration in vaginal opening of female rat, while delay in preputial separation of male after neonatal treatment. Anogenital distances of PND 18 were significantly reduced in sumthrin-treated, and permerhrin-treated male rats after neonatal treatment. All the pyrethroid insecticides tested caused significant increases in uterine weights on PND 18, while significant reductions in the first diestrus phase when neonataly treated. In addition, exposure to pyrethroids in neonatal period led to significant reduction in relative brain weight in female rat on PND 18, but its weight was recovered in diestrus phase. In summary, Our experimental data demonstrate the possibilities of developmental effects of pyrethroid insecticides via estrogenic or antiestrogenic activity.

• Asia-Pacific Journal of Business
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• v.2 no.1
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• pp.1-22
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• 2011

Chamber of commerce and industry plays important role for development of business community and creating vibrant competition. Present paper compares chambers operations in Bangladesh, especially, Sylhet Chamber of Commerce and Industry(SCCI) by reviewing global models of chambers practices. The study identifies important gaps between international standards and Bangladesh practices. Mostly practiced chambers model in the world are: Continental Model, Anglo-Saxon Model and Mixed model or Asian model. Like other Asian countries, chambers in Bangladesh including SCCI, have been following Mixed Model. The empirical study found that SCCI is performing different developmental functions like accumulating members, collecting revenue, fulfilling corporate social responsibility and providing business development services to its members and business community. The notable constraining factors of SCCI operations are: short term orientation in assembling members, limited functional activities, lack of creative endeavors in diversifying services, linkage between SCCI and academic institutions, poor research involvement etc. The necessary suggestions for improvement of chambers performance include adoption of creative measures in various operations, providing training to the members, assisting entrepreneurs in obtaining industrial finance and extending support in the establishment of specialized industrial zone for attaining long term developmental objectives.

• Phonetics and Speech Sciences
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• v.7 no.3
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• pp.165-173
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• 2015

This study was aim to compare the phonological error patterns and PCC(Percentage of Correct Consonants) derived from the single word and spontaneous speech contexts of the speech sound disorders with unknown origin(SSD). The present study suggest that the development phonological error patterns and non-developmental error patterns of the target children, in according to speech context. The subjects were 15 children with SSD up to the age of 5 from 3 years of age. This research use 37 words of APAC(Assessment of Phonology & Articulation for Children) in the single word context and 100 eojeol in the spontaneous speech context. There was no difference of PCC between the single word and the spontaneous speech contexts. Significantly different developmental phonological error patterns between the single word and the spontaneous speech contexts were syllable deletion, word-medial onset deletion, liquid deletion, gliding, affrication, fricative other error, tensing, regressive assimilation. Significantly different non-developmental phonological error patterns were backing, addtion of phoneme, aspirating. The study showed that there was no difference of PCC between elicited single word and spontaneous conversational context. And there were some different phonological error patterns derived from the two contexts of the speech sound disorders. The more important interventions target is the error patterns of the spontaneous speech contexts for the immediate generalization and rising overall intelligibility.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.568-572
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• 2005

This study is aiming for evaluating the factors influencing rehabilitation medical desire in parents (RMDP) with developmental disability children. This study was made with a randomized sample of 156 parents, who were given a questionnaire about how they feel medical needs for their children. The results of the study were as follows: The RMDP is significantly high in relatively the older aged parents group(p<.01). The RMDP is significantly high in severe disability group(p<.01). The RMDP is significantly high in the more spend group of monthly medical cost(p<.05). The group difference of RMDP by monthly income or movement type of disability is not significant(p>.05). It is thought that medical staff need to be actively involved in parents group with developmental disability children to improve motivation, who is relatively the younger than 35 years old or has mild to moderate disability degree of child.

• Anatomy and Cell Biology
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• v.51 no.4
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• pp.243-250
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• 2018

Because of its embryonic origin, the thyroid gland is predisposed to multiple anatomical variations and developmental anomalies. These include the pyramidal lobe, the origin of levator glandular thyroidae, the absence of the isthmus, ectopic thyroid, accessory thyroid tissues, etc. These anatomical variations are clinically significant to surgeons, anatomists, and researchers. The present study was designed to report anatomical variations and developmental anomalies of the thyroid gland in Ethiopian population. The study was conducted on 40 cadavers used for routine dissection classes. The thyroid gland was exposed and observed for any variations and developmental anomalies. The length, width, and thickness of the lobes were measured using a vernier caliper. Differences in the incidence of pyramidal lobe and absence of the isthmus between sexes were tested using a Pearson chi-square test. The mean length, width, and thickness of the right lobe were 4.24 cm, 1.8 cm, and 1.6 cm, respectively, whereas it was 4.08 cm, 1.8 cm, and 1.6 cm, respectively for that of the left lobe. The pyramidal lobe was noted in 52.5% of the cadavers. The levator glandulae thyroidae were prevalent in 40% of the cadavers. The isthmus mainly overlies the 2nd to 4th tracheal rings and was absent in 7.5% of the cadavers. Accessory thyroid tissue and double pyramidal lobes were noted in 2.5% of the cadavers. Most of the variations of the thyroid gland were seen frequently in female but it was not statically significant. Different clinically important and rare variations of the thyroid gland were found.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.30 no.1
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• pp.9-16
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• 2019

Objectives: The purpose of this study was to analyze the discriminant validity and the clinical cut off scores of the Child Behavior Checklist 1.5-5 (CBCL 1.5-5) in the diagnosis of autism spectrum disorder (ASD) and non-ASD. Methods: In total, 104 ASD and 441 non-ASD infants were included in the study. T-test, discriminant analysis, receiver operating characteristic (ROC) curve analysis, and odds ratio analysis were performed on the data. Results: The discriminant validity was confirmed by mean differences and discriminant analysis on the subscales of Emotionally reactive, Somatic complaints, Withdrawn, Sleep problems, Attention problems, Aggressive behavior, Internalizing problems, Externalizing problems, and Total problems, along with the Diagnostic and Statistical Manual of Mental Disorders (DSM)-oriented scales between the two groups. ROC analysis showed that the following subscales significantly separated ASD from normal infants: Emotionally reactive, Somatic complaints, Withdrawn, Sleep problems, Attention problems, Aggressive behavior, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems. Moreover, the clinical cut off score criteria adopted in the Korean-CBCL 1.5-5 were shown to be valid for the subscales Withdrawn, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems. Conclusion: The subscales of Withdrawn, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems significantly discriminated infants with ASD.