• Korean Journal of Veterinary Research
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• v.39 no.3
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• pp.463-471
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• 1999

Magnesium($Mg^{2+}$) is one of the most abundant intracellular divalent cation. Although recent studies demonstrate that adrenergic receptor stimulation evokes marked changes in $Mg^{2+}$ homeostasis, the regulation of $Mg^{2+}$ by dopaminergic receptor stimulation is not yet known. In this work, we used dopaminergic agents to identify which type(s) of receptors were involved in the mobilization of $Mg^{2+}$ by dopaminergic receptor stimulation in the perfused rat hearts, isolated myocytes and circulating blood. The $Mg^{2+}$ content was measured by atomic absorbance spectrophotometry. Dopamine(DA), apomorphine(APO) and pergolide stimulated $Mg^{2+}$ efflux in the perfused rat hearts and these effects were inhibited by haloperidol or fluphenazine, nonselective dopaminergic antagonists. SKF38393, a selective doparminergic agonist, increased $Mg^{2+}$ efflux from the perfused hearts in dose dependant manners and SKF38393-induced $Mg^{2+}$ efflux was blocked by haloperidol. However, dopaminergic agonists-induced $Mg^{2+}$ efflux was potentiated in the presence of sulpiride or eticlopride, $D_2$-selective antagonist, from the perfused hearts. This increase of $Mg^{2+}$ efflux was blocked by haloperidol or imipramine. DA or pergolide increased in circulating $Mg^{2+}$ from blood. By contrast, PPHT stimulated $Mg^{2+}$ influx(a decrease in efflux) from the perfused hearts and circulating blood. PPHT-induced $Mg^{2+}$ influx was blocked by fluphenazine in the perfused hearts. DA-stimulated $Mg^{2+}$ efflux was inhibited by dopaminergic antagoinst in the isolated myocytes. In conclusion, the flux of $Mg^{2+}$ is modulated by DA receptor activation in the rat hearts. The efflux of $Mg^{2+}$ can be increased by $D_1$-receptor stimulation and decreased by $D_2$-receptor stimulation, respectively.

• Journal of Korean Society of Steel Construction
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• v.12 no.3 s.46
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• pp.291-302
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• 2000

In recent years the development of high modulus, high strength and low density boron and graphite fibers bonded together has brought renewed interestes in structural elements. When a plate with arbitrarily oriented layers and clamped boundary conditions is subjected to uniform loading, it is difficult to analyze and apply, compared with isotropic and orthotropic cases. Therefore the numerical methods, such as finite difference method or finite element method, should be emloyed to analyse such problems. In this study the finite difference technique is used to formulate the bending analysis of symmetric composite laminated skew plates. When this technique is used to solve the problem, it is desirable to reduce the order of the derivatives in order to minimize the number of the pivotal points involved in each equation. The 4th order partial differential equations of laminated skew plates are converted to an equivalent three of 2nd order partial differential equations with three dependant variables.

• Proceedings of the Korea Society for Industrial Systems Conference
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• 2002.06a
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• pp.56-56
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• 2002

The embodiment of working process fitting in characteristics of business each other in ERP system is indispensable factor. But, general ERP system is not so much profitable for the way of production management of footwear of domestic midge and small company that is dependant on most of the way of OEM production. Therefore, the development of ERP system fitted for present situation of the footwear manufacturing companies is necessary. For this, first, the business process for footwear production, for development of this system, have to be standardize and second, the model of Integrated system process based on standard business process have to be design for programming. In this paper, we proposed a method to build up standard business process and execute BPP in the point of the foundation for introduction and development of the resource planning systems only used by production of footwear and suited to the way of production management of the domestic companies manufacturing footwear. With this, we presented a process model of resource planning systems for footwear production. This study is focused on construction of integrated process model for production resource planning of ERP subsystems and the integrated process model consist of 13 modules.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.1
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• pp.109-114
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• 2003

Antimicrobial activities of grape seed ethanol extract and its serial solvent fractions were investigated against various food poisoning microorganisms. The grape seed ethanol extract showed dose dependant antimicrobial activity against Bacillus subtilis ATCC 9372 or Staphylococcus aureus ATCC 6538, whereas had limited effect on Pseudomonas aeruginosa IFO 3080, Salmonella enteritidis IFO 3313 and Escherichia coli ATCC 25922. Ethylacetate and butanol fractions ameng the serial solvent fractions of grape seed ethanol extract contained the catechin at the levels of 35.7 mg/g and 20.2 mg/g, respectively. Nevertheless, the butanol fraction of grape seed ethanol extract showed intense antimicrobial activity compared with the ethylacetate fraction on all microorganisms tested. It was found that the butanol fraction was mainly composed of oligomeric or polymeric polyphenols such as condensed tannins by the fractionation on C l8 cartridge according to the difference in the degree of polymerization. Therefore, it seems that the antimicrobial activity of grape seed ethanol extract is related to the degree of polymerization of proanthocyanidin as well as the total content of flavan-3-ol composing the proanthocyanidin.

• Journal of Ginseng Research
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• v.36 no.2
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• pp.211-217
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• 2012

Endophytic fungi were isolated from various tissues (root, stem, petiole, leaf, and flower stalk) of 3- and 4-year-old ginseng plants (Panax ginseng Meyer) cultivated in Korea. The isolated endophytic fungi were identified based on the sequence analysis of the internal transcribed spacer (ITS), 1-5.8-ITS 2. A morphological characterization was also conducted using microscopic observations. According to the identification, 127 fungal isolates were assigned to 27 taxa. The genera of Phoma, Alternaria and Colletotrichum were the most frequent isolates, followed by Fusarium, Entrophospora and Xylaria. Although 19 of the 27 taxa were identified at the species level, the remainder were classified at the genus level (6 isolates), phylum level (Ascomycota, 1 isolate), and unknown fungal species (1 isolate). Endophytic fungi of 13 and 19 species were isolated from 3- and 4-year-old ginseng plants, respectively, and Phoma radicina and Fusarium solani were the most frequently isolated species colonizing the tissues of the 3- and 4-year-old ginseng plants, respectively. The colonization frequency (CF%) was dependant on the age and tissue examined: the CFs of the roots and stems in the 3-year-old ginseng were higher than the CF of tissues in the 4-year-old plants. In contrast, higher CFs were observed in the leaves and petioles of 4-year-old plants, and endophytic fungi in the flower stalks were only detected in the 4-year-old plants. In conclusion, we detected diverse endophytic fungi in ginseng plants, which were distributed differently depending on the age and tissue examined.

• Korean Journal of Plant Resources
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• v.30 no.1
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• pp.22-28
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• 2017

Sophora japonica has been used for treatment of liver and blood-related diseases in herbology. We evaluated whitening activities of Sophorae Flos and Fructus. Sophorae Flos and Fructus were extracted with methanol (MeOH) and divided into petroleum ether, ethyl acetate(EtOAC) and water fraction. For whitening effect by western blot in B16 F10 cells, we analyzed it by investigating the effect of tyrosinase, TRP-l (tyrosinase-related protein 1), TRP-2 (tyrosinase-related protein 2) and MITF (microphthalmia-associated transcription factor) protein expression. The protein expressions of tyrosinase, TRP-1, TRP-2 and MITF in B16 F10 cells treated with Sophorae Flos and Fructus extract were reduced in a dose-dependant manner. Therefore, these results suggest that Sophorae Flos and Fructus have useful plant resource to be developed as functional cosmetic.

• Journal of the East Asian Society of Dietary Life
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• v.17 no.6
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• pp.894-902
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• 2007

This study was performed to observe the quality characteristics of Eunhakong dasik and Small Black Soybean dasik prepared with different addition rates of chlorella powder. For the Hunter's color values, the $L^*,\;a^*,\;and\;b^*$ values of both dasiks decreased with the addition of chlorella powder. The cohesiveness and gumminess of both dasiks were not dependant on the chlorella powder additions. However, the hardness of the Eunhakong dasik with 8% chlorella powder increased. The springiness and brittleness of the Eunhakong dasik had a tendency to decrease as the addition rate of the chlorella powder increased. In terms of sensory quality, both the dasiks were improved by the addition of 4% chlorella powder. Therefore, in subsequent examinations, the chemical characteristics of both dasiks were determined for the 4% addition of chlorella powder. The moisture and crude lipid contents of both dasiks were not influenced by the addition of chlorella powder. Carbohydrate content was highest in the Eunhakong dasik with 0% chlorella powder, and in the Small Black Soybean dasik with 4% chlorella powder. Conversely, crude protein content was highest in the Eunhakong dasik with 4% chlorella powder, and in the Small Black Soybean dasik with 0% chlorella powder. The crude lipid content of the Small Black Soybean dasik with 4% chlorella powder was lower than that of the control without chlorella powder. For mineral content, the K content of both dasiks was not influenced by the addition of chlorella powder. The Ca, Mg, and P contents of both dasiks with 4% chlorella powder, respectively, were lower than those of the dasik with 0% chlorella powder. Finally, the total amino acid content of the Eunhakong dasik tended to decrease, while that of the Small Black Soybean dasik incrased, with the 4% addition of chlorella powder.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.45 no.5
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• pp.95-102
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• 2008

This paper presents an appropriate approach for modeling noise in Computed Radiography(CR) images of high strength materials. The approach is specifically designed for types of noise with the statistical and nonlinear properties. CR images Ere degraded even before they are encoded by computer process. Various types of noise often contribute to contaminate radiography image, although they are detected on digitalization. Quantum noise, which is Poisson distributed, is a shot noise, but the photon distribution on Image Plate(IP) of CR system is not always Poisson process. The statistical properties are relative and case-dependant due to its material characteristics. The usual assumption of a distribution of Poisson, binomial and Gaussian statistics are considered. Nonlinear effect is also represented in the process of statistical noise model. It leads to estimate the noise variance in regions from high to low intensity, specifying analytical model. The analysis approach is tested on a database of steel tube step-wedge CR images. The results are available for the comparative parameter studies which measure noise coherence, distribution, signal/noise ratios(SNR) and nonlinear interpolation.

• Journal of Korea Water Resources Association
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• v.46 no.4
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• pp.389-400
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• 2013

In this study, a conventional pipeline unsteady friction model has been integrated into Levenberg Marquardt method to calibrate friction coefficient in a pipeline system. The method of characteristics has been employed as the modeling platform for the frequency dependant model of unsteady friction. In order to obtain Hessian and Jacobian matrix for optimization, the direct differentiation of pressure to friction factor was calculated and sensitivities to friction for heads and discharges were formulated for implementation to the integration constant in the characteristic method. Using a hypothetical simple pipeline system, time series of pressure, introduced by a sudden valve closure, were obtained for various Reynolds numbers. Convergency in fiction factors were evaluated both in steady and unsteady friction models. The comparison of calibration performance between the proposed method and genetic algorithm indicates that faster and stabler behaviour of Levenberg Marquardt method than those of evolutionary calibration.

• Journal of the Korean Geotechnical Society
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• v.21 no.5
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• pp.75-82
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• 2005

Shear strength parameters obtained from field tests are important factors in the analysis of slope stability. In this paper, sensitivity analysis was performed to evaluate the effect of input parameters on the analysis of slope stability. The input parameters selected for sensitivity analysis were slope angle, cohesion, and friction angle. Monte-Carlo Simulation method was to estimate input parameters for sensitivity analysis in slope stability, and the limit equilibrium method was used to calculate the factor of safety of slope stability. A rock slope, failed in the field, was used for the sensitivity analysis of input parameters in the analysis of slope stability. The result of analysis shows that the factor of safety of the rock slope was a little low. From partial correlation coefficient (PCC) of input parameters from the sensitivity analysis, slope stability was dependant mainly on cohesion and slope angle. The effect of friction angle was smaller than those of cohesion and slope angle on slope stability.