• 제목/요약/키워드: Department of nuclear medicine

검색결과 4,174건 처리시간 0.036초

The Effect of Contrast Agent on the Change of Hepatic Uptake of 99mTc-Mebrofenin in Patients with Liver Transplantation

  • Seung-Hun Yeom;Sang-Hyeong Kil;Yeong-Hyeon Lim;Gwang-Yeol Park;Gyeong-Nam Cho;Seong-Muk Cho;Ji-Ho Seong
    • 핵의학기술
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    • 제28권1호
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    • pp.23-29
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    • 2024
  • Purpose: 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) is an important and clinically useful diagnostic imaging study for detecting complications after liver transplantation. CT contrast agents due to their high atomic numbers, lead to a decrease in gamma ray count rates. This study investigated the impact of CT contrast agents on the uptake of 99mTc-mebrofenin in the liver. Materials and Methods: The quantitative HBS was performed on sixty-two liver transplantation patients (male:female=36:26), with a mean age of 59.4±6.4 years. Statistical comparison of hepatic uptake reduction ratio (HURR%) before and after the injection of CT contrast agents was performed using a paired t-test. Results: Hepatic uptake of the reduction ratio was 94.47±3.65% for the pre-CT contrast agents and 92.17±4.00% for the post-CT contrast agents. HURR% after CT contrast agent injection showed a statistically significant difference compared to before the injection (t=11.09, P<0.001). Conclusion: It will be necessary to pay attention when examining the HBS of patients with liver transplantation after the injection of CT contrast medium. It is advisable to schedule the examination on a different day to prevent residual contrast medium in the body from interfering with the quantitative evaluation of the nuclear medicine examination.

주기성 구토 증후군 환아에서 보인 F-18 FDG PET에서의 뇌 포도당 대사 소견 (Pattern of Cerebral Glucose Metabolism on F-18 FDG Brain PET during Vomiting and Symptom Free Periods in Cyclic Vomiting Syndrome)

  • 김유경;이동수;강은주;서정기;여정석;정준기;이명철
    • 대한핵의학회지
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    • 제35권3호
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    • pp.198-204
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    • 2001
  • Cyclic Vomiting Syndrome (CVS) is characterized by recurrent, periodic, self-limiting vomiting. However, its pathogenesis is not yet established. We investigated the changes of the cerebral glucose metabolism using F-18 FDG during the vomiting attack and symptom free period in two children with CVS. FDG PET study showed the markedly increased metabolism in both temporal lobes and also in the medulla and cerebellum during the vomiting period. Also, FDG PET showed the decreased metabolism un the parieto-occipital and occipital areas during the vomiting period. The area with decreased metabolism seemed to be related with the region showing abnormalities in EEG and perfusion SPECT studies. We expect that what we observed would be a helpful finding in clarifying the pathogenesis of the CVS.

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소아 및 종양 핵의학 영상판독에서 RDF/OWL 데이터의 유용성 (Usefulness of RDF/OWL Format in Pediatric and Oncologic Nuclear Medicine Imaging Reports)

  • 황경훈;이해준;고건;최덕주;선용한
    • 대한의용생체공학회:의공학회지
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    • 제36권4호
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    • pp.128-134
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    • 2015
  • Recently, the structured data format in RDF/OWL has played an increasingly vital role in the semantic web. We converted pediatric and oncologic nuclear medicine imaging reports in free text into RDF/OWL format and evaluated the usefulness of nuclear medicine imaging reports in RDF/OWL by comparing SPARQL query results with the manually retrieved results by physicians from the reports in free text. SPARQL query showed 95% recall for simple queries and 91% recall for dedicated queries. In total, SPARQL query retrieved 93% (51 lesions of 55) recall and 100% precision for 20 clinical query items. All query results missed by SPARQL query were of some inference. Nuclear medicine imaging reports in the format of RDF/OWL were very useful for retrieving simple and dedicated query results using SPARQL query. Further study using more number of cases and knowledge for inference is warranted.

$^{99m}Tc$-MDP 골스캔에서 냉소로 나타난 전이 암의 분석 (Cold Lesions in $^{99m}Tc$-MDP Bone Scans of Patients with Skeletal Metastases)

  • 최창운;양형인;배상균;이동수;손인;정준기;이명철;고창순
    • 대한핵의학회지
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    • 제27권1호
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    • pp.98-103
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    • 1993
  • The present study was purposed to evaluate the incidence and the characteristics of metastatic "cold" lesions in $^{99m}Tc$-MDP bone scans of adult patients with solid malignancies. There were 29 cold lesions in 24 patients. The incidence of cold lesions was about 1% of total cases of bone scans for the patients with malignancy, or 2.5% of cases with bone metastases. Th primary sites of malignancies were lung (four cases), uterine cervix (three cases), kidney, nasopharynx, thyroid, urinary bladder, prostate, lymphoma (two cases each other), liver, breast and others (one case each other). But the relative incidence of cold lesion in lung cancer and breast cancer was low. The most frequent site of cold lesion was spine, and pelvis, skull and rib were followed. The incidence of cold lesion was related to the regional incidence of bone metastases. The size of the cold lesions was greater than that of the hot. There were six cases of single cold lesion without any other abnormalities and two cases of cold lesion which were initially hot. So it should be considered that bone metastases might be presented as cold lesions in bone scan.

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핵의학 영상연구를 위한 몬테칼로 모사코드 (Monte Carlo Simulation Codes for Nuclear Medicine Imaging)

  • 정용현;백철하;이승재
    • Nuclear Medicine and Molecular Imaging
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    • 제42권2호
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    • pp.127-136
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    • 2008
  • Monte Carlo simulation methods are especially useful in studying a variety of problems difficult to calculate by experimental or analytical approaches. Nowadays, they are extensively applied to simulate nuclear medicine instrumentations such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) for assisting system design and optimizing imaging and processing protocols. The goal of this paper is to address the practical issues, a potential user of Monte Carlo simulations for nuclear medicine can encounter, to help them to choose a code. This review introduces the different types of Monte Carlo codes currently available for nuclear medicine, comments main features and properties for a code to be proper for a given purpose, and discusses current research trends in Monte Carlo codes.

Femoral Metastasis in Bone Mineral Densitometry

  • Han-Kyung Seo;Do-Cheol Choi;Cheol-Min Shim;Jin-Hyeong Jo
    • 핵의학기술
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    • 제27권1호
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    • pp.7-8
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    • 2023
  • A 50-year-old female patient referred by the department of breast and thyroid surgery was recommended for orthopedic surgery because lesion like herniation pit was found in the left proximal femur in bone mineral densitometry (BMD). She was later diagnosed with bone metastasis on biopsy in orthopedic surgery. Pelvic X-ray and Lt thigh MRI were performed . Intra-medually nail was operated later. The BMD is a diagnostic method that determines the results by numerical values, so it is inevitable to neglect to observe the bone shape, but as shown in the above case, the examiner's observation of changes in bone shape can return to beneficial treatment for patients.

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