• 한국임상보건과학회지
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• 제4권4호
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• pp.762-768
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• 2016

Purpose. This study was performed on survey related optician's perception of NCS and required jobs to develop curriculum of department of ophthalmic optics Methods. This study was to evaluate the questionnaire survey of 63 opticians working in Optometrist in Daegu Metropolitan City from November 1, 2016 to November 18, 2016. Results. As for the opticians who know about NCS, 23.8% of the respondents answered that the opticians' perception of NCS is very low. For the four required jobs of the technical part, less than 5 years of optometrists ; optometry 73.7% > fitting 47.4% > ophthalmic dispensing 36.8% > lensmeter 5.3%, more than 5 years and less than 10 years of optometrists ; optometry 84.6% > fitting 53.8% > lensmeter 46.2% > ophthalmic dispensing 38.5%, more than 10 years of optometrists ; optometry 67.7% > ophthalmic dispensing 51.4% > lensmeter 19.4% > fitting 16.1%. For the four required jobs of the management, less than 5 years of optometrists ; product 57.9% > service 47.4% > manners 10.6% > sales 5.3%, more than 5 years and less than 10 years of optometrists ; service 76.9% > product 53.9% > manners 46.2% > sales 38.5%, more than 10 years of optometrists ; service 45.2% > manners 42.0% > product 32.3% > sales 19.4%. Conclusions. Although there were 108 required jobs of the technical part and 94 required jobs of the management part, the technical level of the department of ophthalmic optics was satisfactory, but the classes of the management part were insufficient. It will be necessary to actively reflect the needs of industry through curriculums reform.

• International journal of advanced smart convergence
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• 제6권1호
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• pp.18-25
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• 2017

Recently, VR HMD (virtual reality head mounted display) has been utilized for virtual training, entertainment, vision therapy, and optometry. In particular, virtual reality contents are increasingly used for vision therapy and optometry. Accordingly, high-quality virtual reality contents such as a natural vision of life is required. Therefore, it is necessary to study the content production according to the optical characteristics of the VR HMD. The purpose of this paper is to suggest a proper FOV (field of view) of contents according to the distortion rate. We produced virtual reality contents and obtained distorted images by virtual camera. The distortion rate is calculated by using the distorted image. It is proved that the optimal FOV of the VR content with the minimum distortion is $90{\sim}100^{\circ}$. The results of this study are expected to be applied to the production of high quality contents.

• Journal of Applied Biological Chemistry
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• 제61권4호
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• pp.367-370
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• 2018

Lysozyme is an antibacterial enzyme that is found in most of body fluids. Lysozyme in tears plays a primary role in protecting eye from harmful environments; if lysozyme is degraded or inhibited, eyes are likely to be more vulnerable to bacterial infection. In this study, lysozyme activity was evaluated according to varying concentrations of heavy metals, copper, zinc, cobalt and manganese and light metal, calcium that are frequently found in airborne particulate matters and was assayed using a dye-quenching lysozyme substrate, Micrococcus lysodeikticus. Less fluorescence intensity was observed with increasing amounts of copper, zinc, manganese and cobalt but not with calcium suggesting that these metals have some affinity with lysozyme and inhibit lysozyme activity. When albumin, the second most common protein in tears, was added on the reaction of lysozyme and metals, lysozyme activity was partially restored. This finding suggests that the albumin might protect damage caused by metals on lysozyme. To identify whether the decrease in enzymatic activity was related to structural changes of lysozyme, SDS-PAGE was conducted and only with copper did lysozyme show marked smearing bands on the SDS-gel, meaning that copper degraded lysozyme consistent with the sharpest activity decrease.

• 통합자연과학논문집
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• 제12권4호
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• pp.116-121
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• 2019

This experiment is to evaluate the physical properties of the hydrogel lens with the addition of carbon-based nanomaterials, Graphene oxide and Carbon nanotube, and to confirm the improvement of strength. Hyaluronic acid, a hydrophilic substance, was used as an additive by using HEMA (2-hydroxyethyl methacrylate) and ethylene glycol dimethacrylate (EGDMA) as a base monomers. Graphene oxide and two types of Carbon nanotubes(Amide functionalized and Carboxilic acid functionalized) were added 0.1%, 0.3%, 0.5%, respectively, and the physical properties were analyzed by measuring water content, refractive index, breaking strength and SEM image. In the case of the sample added with each carbon nano material, the water content tended to increase for all three materials. The breaking strength tended to increase in Graphene oxide and Carbon nanotube; Carboxilic acid functionalized, but in the case of Carbon nanotube; amide fuctionalized, the breaking strength tended to decrease. However, Carbon nanotube; amide fuctionalized had the highest breaking strength among the three nano materials. Thus, the addition of certain carbon nanomaterials seems to be appropriate for improving the strength of hydrogel lenses.

• 대한화학회지
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• 제62권2호
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• pp.93-98
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• 2018

Bis-GMA, TEGDMA, and camphorquinone were used as the main material, cross-linking agent, and photoinitiator, respectively. In addition, 2-isocyanatoethyl methacrylate was used as an additive for high strength, while the 3-hydroxypyridine was used as an additive for antibacterial activity. Photopolymerization was also carried out at a 440-480 nm wavelength and at about $1000mW/cm^2$ intensity for about 40 seconds. The breaking strength measurement of the samples showed that the breaking strength increased along with increasing the addition ratio of IEM, while it took less time until the polymerization was complete, thereby suggesting that the degree of polymerization has the tendency to increase. And also, compared to the size of the clear zone formed by ampicillin, the 3-hydroxypyridine group exhibited antimicrobial activity induced by ampicillin. The results of this study suggest that the use of 2-isocyanatoethyl methacrylate as an additive for high strength and 3-hydroxypyridine as an additive for improved antibacterial activity would improve the usability of the fabricated polymer as a dental resin cement material with high functionality.

• 환경생물
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• 제28권1호
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• pp.14-19
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• 2010

신생혈관 형성은 세포의 성장 및 상처 치유 과정에서 중요한 현상이다. 그러나 성장인자의 불균형은 시각 및 면역질환과 같은 다양한 질환을 야기한다. 이러한 질환을 치료하는 방법 중 신생혈관 형성을 억제하는 것이 중요한 방법 중 하나이다. AuNPs의 기능과 기전이 신생혈관 형성에 있어서 아직 밝혀진 바가 없다. 현재 PEDF가 항신생혈관 형성 물질로 제안되고 있다. 본 연구에서 우리는 AuNPs가 BRECs에서 VEGF로 유도된 세포의 증식 및 이동, 신생혈관의 형성을 억제하였고 이는 세포의 성장과 침윤 및 전이와 관련된 신생혈관 형성을 억제한다고 사료된다.

• Journal of the Optical Society of Korea
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• 제15권1호
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• pp.68-73
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• 2011

This study investigated, using the Orbscan II topography system, the influence of age and sex related changes on the corneal thickness and anterior corneal curvature, more specifically the fine structure of the cornea, in a Korean young population. The Orbscan II topography system is a computer-assisted slit-beam scanning technology that can map the anterior section of the cornea. The mean central corneal thickness of all subjects was $547.532{\pm}44.529\;{\mu}m$. There was no statistical difference (p>0.5) in the mean central corneal thickness between males and females. Sex and age related changes in the mean central corneal thickness had no specific statistical difference (P>0.5). There was a negative correlation between the anterior corneal curvature and the central corneal thickness in all subjects, except for the twenty year olds. However, the thickness relationship between the mean central corneal and the eight paracentral corneal thicknesses had strong statistical differences in all subjects. Also age and sex related changes in the central corneal thickness and the anterior corneal curvature in all subjects had no statistically significant difference, except from 20-26 years old (p>0.05). This information could be a suitable reference basis for future studies in the young population of Asia and for the development of examination tools for corneal refractive surgery.

• 폴리머
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• 제38권2호
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• pp.220-224
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• 2014

콘택트렌즈용 하이드로젤로의 단백질 흡착량을 시간에 따라 분석하여 계면으로 확산되는 단백질 흡착 반응속도를 연구하였다. HEMA(hydroxyethylmethacrylate)계열 하이드로젤과 silicone계열 하이드로젤을 단백질(알부민 또는 IgG)용액에 침지시킨 후 단백질 흡착량을 시간에 따라 측정하였다. 모든 하이드로젤로의 단백질 흡착량은 단시간(10분)에 급격히 증가한 후 90분 동안 변화 없이 일정하였다. 빠른 단백질 분자의 확산에도 불구하고 계면에너지 감소는 한 시간 이상 진행되는데 이는 계면 탈수 현상이 한 시간 이상 진행되기 때문으로 이해된다. 계면에너지와 단백질 흡착량의 상관관계를 이해하여 콘택트렌즈 재질로의 단백질 흡착 반응 속도의 메커니즘을 분석하였다.

• 한국안광학회지
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• 제13권4호
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• pp.95-101
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• 2008

목적: 본 연구는 양안의 시지각 및 시기능 훈련의 도구로 활용이 가능한 양안 시지각 훈련 프로그램을 제안한다. 방법: 양안 시지각 훈련 시스템을 모듈별로 설계하였고, 입체시와 버전스 훈련이 가능한 입/출력 모듈을 구현하였다. 결과: 본 훈련 프로그램은 입력모듈의 경우, 주시시차의 계산을 통해 인지 거리를 추정할 수 있으며 오차는 5% 미만이었다. 출력모듈의 경우는 28명의 훈련자를 대상으로 입체감 및 깊이인지에 대한 평가를 수행하였고 완전한 입체감을 경험하는 것으로 나타났다. 결론: 따라서, 본 연구에서 제안하는 양안 시지각 훈련프로그램은 시기능 훈련의 도구로 활용이 가능할 것으로 판단된다.

• 통합자연과학논문집
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• 제9권4호
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• pp.249-254
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• 2016

This study evaluated the physical and optical characteristics of hydrophilic ophthalmic polymer with addition of 2-methacryloyloxyethyl phosphorylcholine in the basic hydrogel ophthalmic lens material, and in particular, the utility of 2-methacryloyloxyethyl phosphorylcholine as an ophthalmic contact lens material for ophthalmologic devices was investigated. In this study 2-methacryloyloxyethyl phosphorylcholine were used as additives. For the preparation of hydrogel lens 2-hydroxyethyl methacrylate, methyl methacrylate, acrylic acid and a cross-linker EGDMA were copolymerized in the presence of AIBN as an initiator. The physical properties of the produced polymers were measured as followings. The refractive index of 1.433~1.393, water content of 35.95~53.16%, contact angle of $70.6{\sim}51.24^{\circ}$, UVB transmittance of 81.2~82.4%, UV-B transmittance of 81.2~82.4% and visible transmittance of 91.4~92.2% were obtained. Also, in case of protein absorption, the measurement showed that absorbance of Reference and MPC-10 sample was 0.2598 and 0.2250 respectively. Based on the results of this study, ophthalmic lens material containing 2-methacryloyloxyethyl phosphorylcholine is expected to be used usefully as a material for high wettability and inhibitor of protein adsorption for ophthalmic hydrogel lens.