• Title/Summary/Keyword: DeltaD

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Mind Bomb1 and DeltaD are Localized into Autophagosome after Endocytosis in Zebrafish during Neurogenesis

  • Kim, Min-Jung
    • Development and Reproduction
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    • v.15 no.3
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    • pp.215-221
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    • 2011
  • Endocytosis of the Notch ligand, DeltaD, by mind bomb1 is indispensable for activation of Notch in cell fate determination, proliferation, and differentiation during zebrafish neurogenesis. Loss of mind bomb1 activity as an E3 Ubiquitin ligase causes the accumulation of deltaD at the plasma membrane and results in the ectopic neurogenic phenotype by activation of Notch in early zebrafish embryogenesis. However, the regulatory mechanism of deltaD during neurogenesis is not identified yet. This study aims to analyze the pathway of mib1 and deltaD after endocytosis in vivo during zebrafish embryogenesis. Mind bomb1 and deltaD are co-localized into autophagosome and mutant form of mind bomb1 fails to cargo deltaD into autophagosomes. These findings suggest that mind bomb I mediates deltaD regulation by autophagy in an ubiquitin-dependent manner during zebrafish embryogenesis.

A Design on the A/D converter with architective of ${\sum}-{\Delta}$ (${\sum}-{\Delta}$ modulator의 구조를 갖는A/D 변환기 설계)

  • 윤정식;정정화
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.1C
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    • pp.14-23
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    • 2003
  • This thesis proposes a sigma-delta modulator architecture with 2 Ms/s data rate and 12 bit resolution. A sigma-delta modulate has the features of oversampling and noise shaping. With these features, it can be connected with low resolution A/D converter to achieve higher resolution A/D converter. Most previous researches have been concentrated on high resolution but low data rate applications, e.g. audio applications. But, in order to be applied to various applications such as wireless data communication, researches on sigma-delta modulator architecture for higher data rate are required. The proposed sigma-delta modulator architecture has the sampling rate of 16 times Nyquist rate to achieve high data rate, and consists of a cascade of two 2nd order sigma-delta modulator to get relatively high resolution. The experimental result shows that the proposed architecture achieves 12-bit resolution at 2 Ms/s data rate.

Isolation and Characterization of Double Deletion Mutants of nsdD and veA or nsdC, the Genes Positive Regulating Sexual Development of Aspergillus nidulans (Aspergillus nidulans에서 유성분화 능동조절 유전자 nsdD와 veA 또는 nsdC의 이중결실돌연변이의 분리 및 분석)

  • Kim, Lee-Han;Kim, Ha-Eun;Han, Dong-Min
    • Korean Journal of Microbiology
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    • v.49 no.4
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    • pp.419-423
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    • 2013
  • Three genes, nsdD, nsdC, and veA are known to be necessary for positive regulating sexual development of Aspergillus nidulans. Since the mutants of those genes hardly form fruiting bodies in heterokaryons constructed by cross between two of them, it is difficult to isolate double mutants. In this work, double mutants of ${\Delta}nsdD$ ${\Delta}veA$ and ${\Delta}nsdD$ ${\Delta}nsdC$ were isolated using the characteristic of the nsdD deletion mutant that it could develop mature cleistothecia in hypoxic and low temperature culture condition. According to the phenotypes of double mutants, the nsdD gene controls the apical growth independently with veA or nsdC. Deletion of veA or nsdC was epistatic to nsdD deletion for pigment production. Conidia formation in submerged culture with lactose as sole carbon source was observed in ${\Delta}nsdD$ ${\Delta}nsdC$ double mutant implicating it to be unique phenotype of nsdC deletion.

ANALYTIC TORSION FOR HOLOMORPHIC VECTOR BUNDLES

  • Kim, Hong-Jong
    • Communications of the Korean Mathematical Society
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    • v.9 no.3
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    • pp.669-670
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    • 1994
  • Let $E \to M$ be a hermitian holomorphic vector bundle over a compact (complex) hermitian manifold M of complex dimension n, and let $$ d"_p(E) : 0 \to A^{p,0}(E) \to A^{p,1}(E) \to \cdots \to A^{p,n}(E) \to 0$$ be the Dolbeault complex. Then $A^{p,q}(E)$ become a prehibert space so that the formal adjoint $\delta"$ of $d"$ and the "Laplacian" $\Delta" = \delta" d" + d" \delta"$ are defined.quot; d" + d" \delta"$ are defined.;$ are defined.

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Geochemistry of the Heunghae, Pohang Geothermal Fields, Korea (포항 흥해지역 지열대의 지화학)

  • Yun Uk;Cho Byong-Wook
    • Journal of Soil and Groundwater Environment
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    • v.10 no.6
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    • pp.45-55
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    • 2005
  • The geothermal research has been carried out on the Heunghae, Pohang geothermal area know as having geo-heat-flow area in the Korean peninsula. This study results so far indicate that geothermal water in the area is in peripheral waters of hydrothermal area and is not in equilibrium with the reservoir rock. The average oxygen and hydrogen stable isotope values are as follows: deep groundwater $(average:\;{\delta}^{18}O=-10.1\%_{\circ},\;{\delta}D=-65.8\%_{\circ})$, intermediate groundwater (average: $(average:\;{\delta}^{18}O=-8.9\%_{\circ},\;{\delta}D=-59.6\%_{\circ})$, shallow groundwater $(average:\;{\delta}^{18}O=-8.0\%_{\circ},\;{\delta}D=-53.6\%_{\circ})$, surface water $(average:\;{\delta}^{18}O=-7.9\%_{\circ},\;{\delta}D=-53.3\%_{\circ})$ respectively. Deep groundwaters was originated from a local meteoric water recharged from distant, topographically high mountain region and not affected by the sea water. High temperature zone inferred from water geothermometers is around D-1, D-5, D-6, 1-04 well zones. The estimated enthalpy from Silica-enthalpy mixing model is near 410 kJ/kg, which corresponds to the temperature of $98^{\circ}C$, and in consistent with the result of Na-K and K-Mg geothermometer.

Experimental analysis of the sedimentation processes in the movable weir by changing the channel slope considering weir operation (가동보 운영 및 하상경사 변화에 의한 보 상류 퇴사과정의 실험적 분석)

  • Lee, Kyung Su;Jang, Chang-Lae
    • Journal of Korea Water Resources Association
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    • v.51 no.8
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    • pp.729-737
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    • 2018
  • This study investigates the sediment processes the Improved-pneumatic-movable weir through laboratory experiments considering changing channel slopes. Experimental results show that the delta migrates towards the weir and the delta height increases as time passes. Moreover, as the delta approaches the weir, the delta migration speed decreases. As the dimensionless delta location increases, the effective height of dimensionless delta and the dimensionless reservoir capacity increases. Therefore, under the same slope conditions, the sediment deposition volume of the delta is small as the channel slope is mild. This means that the channel slope affects the development of the delta in the upstream of the Improved-pneumatic-movable weir. At the beginning of the experiment, the foreset slope is mild. However, the foreset slope of the delta increases with water depth as the delta migrates downstream. Moreover, as the slope is mild, the ratio of delta front length to delta height is close to 1, and the dimensionless delta height and the dimensionless delta migration speed decrease. As the delta height increases, the water depth, the velocity approaching to the weir and the delta migration speed decrease.

THE LATTICE DISTRIBUTIONS INDUCED BY THE SUM OF I.I.D. UNIFORM (0, 1) RANDOM VARIABLES

  • PARK, C.J.;CHUNG, H.Y.
    • Journal of the Korean Mathematical Society
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    • v.15 no.1
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    • pp.59-61
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    • 1978
  • Let $X_1$, $X_2$, ${\cdots}$, $X_n$ be i.i.d. uniform (0,1) random variables. Let $f_n(x)$ denote the probability density function (p.d.f.) of $T_n={\sum}^n_{i=1}X_i$. Consider a set S(x ; ${\delta}$) of lattice points defined by S(x ; ${\delta}$) = $x{\mid}x={\delta}+j$, j=0, 1, ${\cdots}$, n-1, $0{\leq}{\delta}{\leq}1$} The lattice distribution induced by the p.d.f. of $T_n$ is defined as follow: (1) $f_n^{(\delta)}(x)=\{f_n(x)\;if\;x{\in}S(x;{\delta})\\0\;otherwise.$. In this paper we show that $f_n{^{(\delta)}}(x)$ is a probability function thus we obtain a family of lattice distributions {$f_n{^{(\delta)}}(x)$ : $0{\leq}{\delta}{\leq}1$}, that the mean and variance of the lattice distributions are independent of ${\delta}$.

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Initiation and Propagation Behaviors of Micro-Surface-Fatigue Cracks under In-Plane Tension Fatigue Tests (引張 軸荷重 疲勞 에 의한 微小表面 균열 의 發생 . 成長擧動)

  • 서창민
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.9 no.1
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    • pp.1-9
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    • 1985
  • In-plane tension fatigue tests (R = 0.05) were carried out to investigate the initiation and propagation behaviors of micro-surface-fatigue cracks on smooth surfaces of a mild steel. Also, the investigations of saturated cyclic strain which can be obtained by the fatigue tests have been made via the cyclic strain intensity factor, .DELTA. $K_{\epsilon}$/, for the purpose of unifying two approaches of the study of fatigue; the one approach is based on the fracture mechanics concept and the other on lowcycle fatigue concept. Some of the results are as follows; The growth rate, d(2a)/dN, of small cracks cannot be represented by one straight line as a function of .DELTA.K for various of the nominal stress range, .DELTA..sigma., and is higher than that of a larger through crack. The rearrangement of the d(2a)/dN by .DELTA..epsilon..root..pi.s( = .DELTA. $K_{\epsilon}$/) with the stress range .DELTA..epsilon. in .DELTA.K replaced by .DELTA..epsilon., strain range, gives one straight line of the .DELTA. $K_{\epsilon}$-d(2a)/dN relation for various values of stress range .DELTA.$_{\epsilon}$../.X>../.

SUBORDINATION ON δ-CONVEX FUNCTIONS IN A SECTOR

  • MARJONO, MARJONO;THOMAS, D.K.
    • Honam Mathematical Journal
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    • v.23 no.1
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    • pp.41-50
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    • 2001
  • This paper concerns with the subclass of normalized analytic function f in D = {z : |z| < 1}, namely a ${\delta}$-convex function in a sector. This subclass is denoted by ${\Delta}({\delta})$, where ${\delta}$ is a real positive. Given $0<{\beta}{\leq}1$ then for $z{\in}D$, the exact ${\alpha}({\beta},\;{\delta})$ is found such that $f{\in}{\Delta}({\delta})$ implies $f{\in}S^*({\beta})$, where $S^*({\beta})$ is starlike of order ${\beta}$ in a sector. This work is a more general version of the result of Nunokawa and Thomas [11].

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Tunneling Characteristics in $Pb/Bi_2Sr_2CaCu_2O_{8+\delta}$ Junctions as an Evidence for a d-wave Order Parameter Symmetry in $Bi_2Sr_2CaCu_2O_{8+\delta}$ Superconductors ($Bi_2Sr_2CaCu_2O_{8+\delta}$ 고온초전도체의 d-파 대칭성 증거로서의 $Pb/Bi_2Sr_2CaCu_2O_{8+\delta}$접합 투과전도특성)

  • Chang, Hyun-Sik;Lee, Hu-Jong
    • Progress in Superconductivity
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    • v.2 no.2
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    • pp.65-70
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    • 2001
  • $Pb/Bi_2Sr_2CaCu_2O_{8+\delta}$-single-crystal junctions with the tunneling direction along the c axis of the crystal were fabricated to obtain an s-wave-superconductor/d-wave-superconductor Josephson junctions. The tunneling R (T) curves and current-voltage characteristics show distinct features which can be explained only under the assumption that the order parameter of high-$T_c/Bi_2Sr_2CaCu_2O_{8+{\delta}}$ superconductors has a pure d-wave symmetry, which is in contrast to the case of $YBa_2Cu_3O_{7+{\delta$}}$erconductors where a minor s-wave component is also present..

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