• Title/Summary/Keyword: Delta-1

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Detection of Protein Kinase C Isoenzymes in the Growth of Human Epidermal Keratinocytes by Growth Factors (Growth Factor를 처리한 피부상피세포로부터 Protein Kinase C Isoenzyme의 검출)

  • Eun-Young Joo;Nam-Woo Kim
    • Biomedical Science Letters
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    • v.6 no.2
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    • pp.83-91
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    • 2000
  • Subconfluent neonatal human epidermal keratinocytes were treated with a concentration 200 ng/$m\ell$ of human recombinant epidermal growth factor (hrEGF), human recombinant insulin-like growth factor-1 (hrIGF-1), and with a combination of hrEGF and hrIGF-1. Cytoplasmic and membrane-associated proteins were extracted and assayed. Proteins were separated by SDS-PAGE, and subjected to the western blot analysis. In the cytoplasmic fraction, the PKC concentration of keratinocyte treated with hrIGF-1 was higher than the control group, but the concentration of control group was the highest than the others in the membrane fraction. In the cytoplasmic fraction, EGF stimulated PKC-$\beta$II, -$\delta$, -$\theta$, and also stimulated PKC-$\alpha$, -$\beta$I, -$\delta$, -$\Im$ and -$\theta$ in the membrane fraction. IGF-1 stimulated PKC-$\beta$I, -$\Im$ and -$\theta$ in the cytoplasmic, PKC-$\alpha$, -$\beta$I, -$\delta$, -$\Im$, - $\varepsilon$ and -$\theta$ in the membrane. In the cells treated with a combination of EGF and IGF-1, PKC-$\alpha$, -$\beta$I, -$\Im$ and -$\theta$ in the cytoplasmic fraction, PKC-$\alpha$, -$\delta$, -$\Im$, -$\varepsilon$ and -$\theta$ in the membrane fraction were stimulated.

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A $4^{th}$-Order 1-bit Continuous-Time Sigma-Delta Modulator for Acoustic Sensor (어쿠스틱 센서 IC용 4차 단일 비트 연속 시간 시그마-델타 모듈레이터)

  • Kim, Hyoung-Joong;Lee, Min-Woo;Roh, Jeong-Jin
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.46 no.3
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    • pp.51-59
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    • 2009
  • This paper presents the design of continuous-time sigma-delta modulator for acoustic sensor. The feedforward structure without summing block is used to reduce power consumption of sigma-delta modulator. A high-linearity active-RC filter is used to improve resolution of sigma-delta modulator. Excess loop delay problem in conventional continuous-time sigma-delta modulators is solved by our proposed architecture. A low power, high resolution fourth-order continuous-time sigma-delta modulator with 1-bit quantization was realized in a 0.13-${\mu}m$ 1-Poly 8-metal CMOS technology, with a core area of $0.58\;mm^2$. Simulation results show that the modulator achieves 91.3-dB SNR over a 25-kHz signal bandwidth with an oversampling ratio of 64, while dissipating $290{\mu}W$ from a 3.3-V supply.

Retrieval of LIDAR Aerosol Parameter Using Sun/Sky Radiometer at Gangneung, Korea

  • Shin, Sung-Kyun;Lee, Kwon-Ho;Lee, Kyu-Tae
    • Current Optics and Photonics
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    • v.1 no.3
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    • pp.175-185
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    • 2017
  • The aerosol optical properties such as depolarization ratio (${\delta}$) and aerosol extinction-to-backscatter ratios (S, LIDAR ratio) and ${\AA}ngstr{\ddot{o}m$ exponent (${\AA}$) derived from measurement with AERONET sun/sky radiometer at Gangneung-Wonju National University (GWNU), Gangneung, Korea ($37.77^{\circ}N$, $128.87^{\circ}E$) during a winter season (December 2014 - February 2015) are presented. The PM concentration measurements are conducted simultaneously and used to identify the high-PM events. The observation period was divided into three cases according to the PM concentrations. We analysed the ${\delta}$, S, and ${\AA}$ during these high PM-events. These aerosol optical properties are calculated by the sun/sky radiometer data and used to classify a type of aerosols (e.g., dust, anthropogenic pollution). The higher values of ${\delta}$ with lower values of S and ${\AA}$ were measured for the dust particles. The mean values of ${\delta}$, S, and ${\AA}$ at 440-870 nm wavelength pair (${\AA}_{440-870}$) for the Asia dust were 0.19-0.24, 36-56 sr, and 0.48, respectively. The anthropogenic aerosol plumes are distinguished with the lower values of ${\delta}$ and higher values of ${\AA}$. The mean values of spectral ${\delta}$ and ${\AA}_{440-870}$ for this case varied 0.06-0.16 and 1.33-1.39, respectively. We found that aerosol columnar optical properties obtained from the sun/sky radiometer measurement are useful to identify the aerosol type. Moreover, the columnar aerosol optical properties calculated based on sun/sky radiometer measurements such as ${\delta}$, S, and ${\AA}$ will be further used for the validation of aerosol parameters obtained from LIDAR observation as well as for quantification of the air quality.

The Different Isotopic Signatures of Co-existing Zooplankton Species in Two Alpine Lakes (두 삼림호수에 공존하는 동물플랑크톤종의 다른 안정동위원소비)

  • Lee, Jae-Yong;Kim, Bom-Chul;Yoshioka, Takahito;Hino, Shuji
    • Korean Journal of Ecology and Environment
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    • v.41 no.3
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    • pp.294-300
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    • 2008
  • The stable isotopes ratios ($\delta^{13}C\;and\;\delta^{15}N$) of two coexisting species of zooplankton (Daphnia longispina and Acanthodiaptomus pacificus) and POM were determined in two alpine lakes in Japan. The difference of $\delta^{13}C$ between A. pacificus and D. longispina was 4.1$\pm$0.9‰ in Lake Shirakoma, which was larger than in Lake Panke. Whereas the difference of $\delta^{15}N$ between A. pacificus and D. longispina (2.6$\pm$0.8‰) was larger in Lake Panke than in Lake Shirakoma. $\delta^{13}C$ of POM (-26.6$\pm$1.2‰) in Lake Shirakoma was different from those of zooplankton; it was heavier than those of D. longispina and A. pacificus by 3.7$\pm$1.6‰ and 7.8$\pm$1.0‰, respectively. Whereas $\delta^{15}N$ of POM (2.0$\pm$0.8‰) was similar with those of both A. pacificus and D. longispina. This implies that the two lakes may have different trophic structure and food sources for zooplankton, and each species are grazing on selectively different components of POM. The temporal variation of $\delta^{13}C$ for each zooplankton species was associated with lipid contents of zooplankton in both lakes. The results showed that stable isotope composition of zooplankton can be an useful information for understanding energy pathways and trophic structures in lakes.

NONTRIVIAL SOLUTIONS FOR THE NONLINEAR BIHARMONIC SYSTEM WITH DIRICHLET BOUNDARY CONDITION

  • Jung, Tacksun;Choi, Q-Heung
    • Korean Journal of Mathematics
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    • v.18 no.4
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    • pp.473-487
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    • 2010
  • We investigate the existence of multiple nontrivial solutions (${\xi}$, ${\eta}$) for perturbations $g_1$, $g_2$ of the harmonic system with Dirichlet boundary condition $${\Delta}^2{\xi}+c{\Delta}{\xi}=g_1(2{\xi}+3{\eta})\;in\;{\Omega}\\{\Delta}^2{\eta}+c{\Delta}{\eta}=g_2(2{\xi}+3{\eta})\;in\;{\Omega}$$ where we assume that ${\lambda}_1$ < $c$ < ${\lambda}_2$, $g^{\prime}_1({\infty})$, $g^{\prime}_2({\infty})$ are finite. We prove that the system has at least three solutions under some condition on $g$.

EXISTENCE AND MULTIPLICITY RESULTS FOR SOME FOURTH ORDER SEMILINEAR ELLIPTIC PROBLEMS

  • Jin, Yinghua;Wang, Xuechun
    • Korean Journal of Mathematics
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    • v.17 no.4
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    • pp.473-480
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    • 2009
  • We prove the existence and multiplicity of nontrivial solutions for a fourth order problem ${\Delta}^2u+c{\Delta}u={\alpha}u-{\beta}(u+1)^-$ in ${\Omega}$, ${\Delta}u=0$ and $u=0$ on ${\partial}{\Omega}$, where ${\lambda}_1{\leq}c{\leq}{\lambda}_2$ (where $({\lambda}_i)_{i{\geq}1}$ is the sequence of the eigenvalues of $-{\Delta}$ in$H_0^1({\Omega})$) and ${\Omega}$ is a bounded open set in $R^N$ with smooth boundary ${\partial}{\Omega}$. The results are proved by applying minimax arguments and linking theory.

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The Study on the Influence of the Concentration NaCl Solution on Corrosion Fatigue Behavior of T.M.C.P. Steel (T.M.C.P. 강의 부식피로거동에 미치는 염분의 영향에 관한 연구)

  • 이상호;한정섭
    • Journal of Ocean Engineering and Technology
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    • v.7 no.2
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    • pp.131-140
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    • 1993
  • To study the corrosion fatigue begavior of T.M.C.P. steel, the rotary bending fatigue test with the change of concentration of NaCl solution was carried out. Fatigue life in the corrosion environment is decreased markedly in comparision with that in the air. Fatigue limit in the air was about 225 MPa. In case of 3.5% NaCl solution fatigue life could be expressed as .sigma./sub f/=10,392 * (N/sub f/)/sup -o.2923 . According to the paris's rule, crack growth rates could be expressed as da/dN=2.62.*10/sup -7/ .DELTA. K/sup 1.09/(3.5% NaCl solution), da/dN=1.95 *10/sup -7 .DELTA. K/sup 1.05/(1% NaCl solution), da/dN=2.62 * 10/sup -7/.DELTA./sup 0.72/(0.01% NaCl solution) with da/dN expressed in mm/cycle and .DELTA.K in MPa.GAMMA.m. The crack growth rate in the corrosion environment was highest under 3.5% NaCl solution.

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Theoretical Study of Phosphoryl Transfer Reactions

  • Han, In-Suk;Kim, Chan-Kyung;Lee, Hai-Whang
    • Bulletin of the Korean Chemical Society
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    • v.32 no.3
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    • pp.889-893
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    • 2011
  • The energetics and transition state (TS) structures of the reactions of six substrates, $R_1R_2P$(=O or S)Cl-type where $R_1=R_2$=Me and/or MeO, with ammonia in acetonitrile are theoretically investigated at the level of CPCM-MP2/6-31+G(d) and CPCM-MP2/6-311+G(3df,2p). The degrees of distortion of TS from the ideal trigonal bipyramidal pentacoordinate, ${\Delta}{{\delta}}_{{\neq}b}$ for a backside and ${\Delta}{{\delta}}_{{\neq}f}$ for a frontside attack, are calculated. The results of calculation suggest that the feasibility of a frontside attack for P=S is greater than that for P=O system when the two ligands, $R_1$ and $R_2$, becomes larger. The experimental and calculated results of anilinolyses of $R_1R_2P$(=O or S)Cl-type show the consistent tendencies.

Multi-bit Sigma-Delta Modulator for Low Distortion and High-Speed Operation

  • Kim, Yi-Gyeong;Kwon, Jong-Kee
    • ETRI Journal
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    • v.29 no.6
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    • pp.835-837
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    • 2007
  • A multi-bit sigma-delta modulator architecture is described for low-distortion performance and a high-speed operation. The proposed architecture uses both a delayed code and a delayed differential code of analog-to-digital converter in the feedback path, thereby suppressing signal components in the integrators and relaxing the timing requirement of the analog-to-digital converter and the scrambler logic. Implemented by a 0.13 ${\mu}m$ CMOS process, the sigma-delta modulator achieves high linearity. The measured spurious-free dynamic range is 89.1 dB for -6 dBFS input signal.

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The Influence of Ascorbic Acid and Methionine on the $\delta$-Aminolevulinic Acid Dehydratase Activity in Lead Poisoning. (납중독에 있어서 $\delta$-Aminolevulinic Acid Dehydratase 활성에 미치는 Ascorbic Acid 및 Methionine의 효과에 관한 연구)

  • 윤혜정
    • YAKHAK HOEJI
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    • v.19 no.1
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    • pp.21-29
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    • 1975
  • The activity of $\delta$-aminolevlinic acid dehydratase (ALAD) in red cell of rabbit inhibited by addition of $Pb(Ac)_{2}$(50mg/kg) to rabbit caused to diminish completely the ALAD activity in blood within shr. Pretreatment of ascorbic acid and methionine decreased the increment of $\delta$-aminolevulinic acid output in urine by lead poisoning.

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