• Title/Summary/Keyword: Delivery Method

Search Result 1,945, Processing Time 0.033 seconds

Development and evaluation of probiotic delivery systems using the rennet-induced gelation of milk proteins

  • Ha, Ho-Kyung;Hong, Ji-Young;Ayu, Istifiani Lola;Lee, Mee-Ryung;Lee, Won-Jae
    • Journal of Animal Science and Technology
    • /
    • v.63 no.5
    • /
    • pp.1182-1193
    • /
    • 2021
  • The aims of this study were to develop a milk protein-based probiotic delivery system using a modified rennet-induced gelation method and to determine how the skim milk powder concentration level and pH, which can affect the rennet-induced intra- and inter-molecular association of milk proteins, affect the physicochemical properties of the probiotic delivery systems, such as the particle size, size distribution, encapsulation efficiency, and viability of probiotics in simulated gastrointestinal tract. To prepare a milk protein-based delivery system, skim milk powder was used as a source of milk proteins with various concentration levels from 3 to 10% (w/w) and rennet was added to skim milk solutions followed by adjustment of pH from 5.4 or 6.2. Lactobacillus rhamnosus GG was used as a probiotic culture. In confocal laser scanning microscopic images, globular particles with a size ranging from 10 ㎛ to 20 ㎛ were observed, indicating that milk protein-based probiotic delivery systems were successfully created. When the skim milk powder concentration was increased from 3 to 10% (w/w), the size of the delivery system was significantly (p < 0.05) increased from 27.5 to 44.4 ㎛, while a significant (p < 0.05) increase in size from 26.3 to 34.5 ㎛ was observed as the pH was increased from 5.4 to 6.4. An increase in skim milk powder concentration level and a decrease in pH led to a significant (p < 0.05) increase in the encapsulation efficiency of probiotics. The viability of probiotics in a simulated stomach condition was increased when probiotics were encapsulated in milk protein-based delivery systems. An increase in the skim milk powder concentration and a decrease in pH resulted in an increase in the viability of probiotics in simulated stomach conditions. It was concluded that the protein content by modulating skim milk powder concentration level and pH were the key manufacturing variables affecting the physicochemical properties of milk protein-based probiotic delivery systems.

A Study on the Improvement of Safety Management for Delivery Platform Workers (배달 플랫폼 종사자를 위한 안전관리 개선방안에 관한 연구)

  • Jun-Ho Moon;Hong-Kwan Kim
    • Journal of the Society of Disaster Information
    • /
    • v.19 no.1
    • /
    • pp.84-96
    • /
    • 2023
  • Purpose: In this study, to protect delivery platform workers from danger, we intend to propose a plan to improve safety management. Method: To protect delivery platform workers, safety-related legal systems and cases were found and analyzed, and statistical results derived from a survey of delivery platform workers were analyzed, and safety management improvement measures were presented. Result: In Korea, safety measures against weather deterioration were not clearly presented in the contents of the law for the safety of delivery platforms, and the survey confirmed that safety education was not fully conducted, and most of them experienced accidents by receiving calls through apps or programs during delivery. Conclusion: This study could suggest safety management improvement plans for delivery platform workers, but since detailed questionnaire items related to motorcycles were not investigated, various accident results that could occur due to motorcycles used by delivery platform workers could not be identified.

Development of Hydrophobically Modified Casein Derivative-Based Delivery System for Docosahexaenoic Acids by an Acid-Induced Gelation

  • Ho-Kyung Ha;Dan-Bi Woo;Mee-Ryung Lee;Won-Jae Lee
    • Food Science of Animal Resources
    • /
    • v.43 no.2
    • /
    • pp.220-231
    • /
    • 2023
  • Although omega-3 fatty acids including docosahexaenoic acid (DHA) contain various health-promoting effects, their poor aqueous solubility and stability make them difficult to be induced in dairy foods. The aims of this research were to manufacture casein derivative-based delivery system using acid-induced gelation method with glucono-σ-lactone and to investigate the effects of production variables, such as pH and charged amount of linoleic acid, on the physicochemical properties of delivery systems and oxidative stability of DHA during storage in model milk. Covalent modification with linoleic acid resulted in the production of casein derivatives with varying degrees of modification. As pH was reduced from 5.0 to 4.8 and the charged amount of linoleic acid was increased from 0% to 30%, an increase in particle size of casein derivative-based delivery systems was observed. The encapsulation efficiency of DHA was increased with decreased pH and increased charged amount of linoleic acid. The use of delivery system for DHA resulted in a decrease in the development of primary and secondary oxidation products. An increase in the degree of modification of casein derivatives with linoleic acid resulted in a decrease in the formation of primary and secondary oxidation products than of free DHA indicating that delivery systems could enhance the oxidative stability of DHA during storage in model milk. In conclusions, casein derivatives can be an effective delivery system for DHA and charged amount of linoleic acid played a key role determining the physicochemical characteristics of delivery system and oxidative stability of DHA.

Architecture of XRML-based Comparison Shopping Mall and Its Performance on Delivery Cost Estimation (XRML 기반 비교쇼핑몰의 구조와 배송비 산정에 관한 실증분석)

  • Lee Jae Kyu;Kang Juyoung
    • Journal of the Korean Operations Research and Management Science Society
    • /
    • v.30 no.2
    • /
    • pp.185-199
    • /
    • 2005
  • With the growth of internet shopping malls, there is increasing interest in comparison shopping mall. However most comparison sites compare only book prices by collecting simple XML data and do not provide .the exact comparison Including precise shipping costs. Shipping costs vary depending on each customer's address, the delivery method, and the category of selected goods, so rule based system is required in order to calculate exact shipping costs. Therefore, we designed and implemented comparison shopping mall which compares not only book prices but also shipping costs using rule based inference. By adopting the extensible Rule Markup language (XRML) approach, we proposed the methodology of extracting delivery rules from Web pages of each shopping mall. The XRML approach can facilitate nearly automatic rule extraction from Web pages and consistency maintenance between Web pages and rule base. We developed a ConsiderD system which applies our rule acquisition methodology based on XRML. The objective of the ConsiderD system is to compare the exact total cost of books including the delivery cost over Amazon.com, BarnesandNoble.com, and Powells.com. With this prototype, we conducted an experiment to show the potential of automatic rule acquisition from Web pages and illustrate the effect of delivery cost.

Performance Evaluation of Commercial Document Delivery Suppliers Accessible through the Internet (인터넷을 통하여 접속가능한 상업적 문헌전달서비스의 성능 평가)

  • 장혜란
    • Journal of the Korean Society for information Management
    • /
    • v.17 no.1
    • /
    • pp.89-101
    • /
    • 2000
  • In recent years the service of commercial document delivery has mutured in the library and information field. The aim of this paper is to evaluate the performance of the major document delivery suppliers accessible through the internet. Actual article requests in science and technology were sampled systematically and forwarded to the suppliers selected. Processing data was collected and analyzed in terms of fill rate, delivery time, and cost. Method of delivery was also a criteria of analysis. Results shows that the performance of the commercial suppliers varies according to the criteria. And the knowledge about vendor services and citation verification are important factors affecting the document delivery capability. Finally recommendations based on the results are briefly examined.

  • PDF

The Determinants and Barriers of Outsourcing Third-Party Online Delivery: Perspectives of F&B Entrepreneurs in Malaysia

  • SIN, Kit-Yeng;LO, May-Chiun;MOHAMAD, Abang Azlan
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.8 no.5
    • /
    • pp.979-986
    • /
    • 2021
  • Online food delivery and food delivery apps have continued to grow exponentially in Malaysia. Fundamental aspects in entrepreneurship of the food and beverage industry, such as knowledge and attitudes towards online food delivery services being outsourced, have yet to be extensively recognized. The present study intends to explore this area of subject matter within the Malaysian context by using behavioral reasoning theory. The actual interview for this study took place in May 2020, and 14 interviews had been carried out. All interviews were audio-recorded with the consent from the respondents for reference purposes and subsequently transcribed verbatim. The transcripts were then checked against audio records. Content analysis was used to analyze the transcripts by focusing on n frequency counts and coding of themes. A qualitative method has been adopted by employing an interview to elicit the perspectives of entrepreneurs from Sarawak on the determinants and barriers in outsourcing online food delivery services. Results indicate that high potential in revenue, broad exposure to reach customers, convenience, and provision of job opportunities are the four factors that determine to outsource. In contrast, food quality maintenance, trustworthiness, high cost incurred, and consumer technology resistance are four factors that serve as barriers towards outsourcing third-party online delivery.

Tranilast-delivery surgical sutures to ameliorate wound healing by reducing scar formation through regulation of TGF-β expression and fibroblast recruitment

  • Choi, Sung Yoon;Kim, Byung Hwi;Huh, Beom Kang;Jeong, Woong;Park, Min;Park, Hyo Jin;Park, Ji-Ho;Heo, Chan Yeong;Choy, Young Bin
    • Journal of Industrial and Engineering Chemistry
    • /
    • v.67
    • /
    • pp.469-477
    • /
    • 2018
  • We describe surgical sutures enabled with the local, sustained delivery of a TGF-${\beta}$ inhibitory drug, tranilast. To fabricate drug-delivery sutures, we separately prepared a tranilast-loaded strand using poly (lactic-co-glycolic acid), which was then physically braided with a surgical suture already in clinical use. By this method, the drug-delivery sutures maintained the mechanical strength and allowed the modulation of drug release profiles by simply altering the tranilast-loaded strand. The drug-delivery sutures herein released tranilast for up to 14 days. When applied to animal models, scarring was indeed reduced with diminished TGF-${\beta}$ expression and fibroblast numbers during the entire 21 day testing period.

A Parallel Transmission Overlay Multicast Scheme for Massive Contents Delivery (대용량 콘텐츠 전송을 위한 병렬전송 오버레이 멀티캐스트)

  • Park, Jin-Hong;;Kim, Seon-Ho;Shin, Yong-Tae;Shin, Seok-Kyoo
    • Journal of KIISE:Information Networking
    • /
    • v.32 no.5
    • /
    • pp.593-602
    • /
    • 2005
  • Overlay multicast delivery method is a new approach in which multicast functionality is implemented at the end-hosts application layer in the timing of sparse deployment of IP multicast. However, existing overlay multicast protocols are not being standardization and many restrictions occur when delivering high capacity contents. Therefore, new delivery mechanism is required for the overlay multicast based high capacity contents delivery. In this paper. we separate group management and delivery management of overlay multicast and describe a capable group management. We also defined high speed delivery method better than that of existing overlay multicast through use of collaborated distribute downloading. This improved efficiency of massive contents transmission.

Improvement of Public Construction Delivery System & Award Method in Korea;Comparison with Cases of U.S., U.K., Japan (국내 공공공사 발주 및 낙찰제도 개선방안;미국, 영국, 일본 사례와의 비교를 중심으로)

  • Ji, Sae-Hyun;Lee, Hyun-Soo;Park, Moon-Seo;Song, Sang-Hun
    • Proceedings of the Korean Institute Of Construction Engineering and Management
    • /
    • 2006.11a
    • /
    • pp.367-372
    • /
    • 2006
  • Government is not only the biggest owner in public sector, but also the leader responsible for improving and fostering construction industry. Delivery systems and award methods are enacted as laws via government's strong will for construction innovation. In addition to establishing relationships between government and contractor, delivery systems and award methods affect every aspect of industry. Therefore, the government should keep trying to remove inefficiency and achieve Best Value. This paper analyzes the delivery systems and award methods of advanced countries to extract lessons for Korean industry focusing on leading parties, direction, and change in owner's awareness of their respective innovative movements for construction. The prerequisites for improvement in delivery systems and award methods are suggested as partnership between public and private sectors, consistent innovation, enhancement in efficiency, and reinforcement of owner's capability.

  • PDF

The Clinical Analysis of 104 Sanhupung Patients that visited at an Oriental Medicine Hospital. (일개 한의대 부속 한방병원에 산후풍으로 내원한 환자 104례에 대한 실태 분석)

  • Jang, Se-Ran;Park, Young-Sun;Kim, Dong-Chul
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.23 no.3
    • /
    • pp.192-204
    • /
    • 2010
  • Purpose: Sanhupung's pathological conditions is different from non-postpartum's disease. So it is important to analyze Sanhupung's construction, onset factors and Oriental theraphy. Methods: We studied 104 Sanhupung women visiting $\bigcirc\bigcirc$ hospital form January 2008 to December 2009. We analyzed the general characteristics, kinds of symptoms and Oriental theraphy's present condition. Also We compared patients' age, the number of live births and delivery month to the National Statistical Office's results. Results: 1. Patients over the age of 30, who have one child and who gave birth in September(14.42%) and in Summer(43.26%) occupied the highest percentage. But delivery method was not correlated with Sanhupung. 2. Musculo-skeletal symptoms(42.13%) were the most common symptoms. Wrist, waist, knees(59.59%) were the most common pain areas and the other pain symptoms (40.21%) appeared a significant portion of cases respectively. 3. In the 21~30days after delivery, the most patients visited. The number of patients admitted within 30 days after delivery or within 90 days was small comparing with Sanhupung onset. Patients treated within 10 days(47.12%) and treated only herb medicine(54.90%) were the most common. And the patients responded satisfacion or over were 88.46%. Conclusion: Patients' age, the number of born babies, delivery time were correlated with Sanhupung symptoms, but the method of delivery was not associated. And musculo-skeletal symptoms were the most common symptoms. Sanhupung patient's treatment period and methods were limited.