• 정보처리학회논문지D
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• 제12D권1호
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• pp.21-30
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• 2005

이동 컴퓨팅 환경에서 이동 호스트는 대역폭의 사용을 줄이고 이동 트랜잭션의 응답 시간을 향상시키기 위하여 캐쉬를 사용한다. 그리고 서버는 이동 호스트의 캐쉬 일관성을 유지하기 위해서 주기적으로 갱신된 데이터를 방송한다. 그러나 무효화 보고서를 사용한 캐쉬 일관성 유지기법은 이동 트랜잭션의 완료 결정을 지연한다는 문제점을 가지고 있다. 본 논문에서는 캐슁된 데이터를 사용하여 이동 트랜잭션을 수행하는 경우 이동 트랜잭션의 직렬 가능한 수행을 보장하는 CCM-AD 방법을 제안한다. 제안하는 CCM-AD 방법은 서버에서 이동 호스트에게 방송한 데이터와 갱신된 데이터와의 교집합을 구하여 공통되는 데이터를 요청 데이터와 함께 방송함으로써 이동 트랜잭션의 직렬 가능한 수행을 보장한다. 그리고 수행 후 완료 결정을 위한 이동 트랜잭션의 지연도 줄일 수 있다. 또한 주기적으로 방송하는 무효화 보고서의 메시지 크기도 줄일 수 있다.

• 한국컴퓨터정보학회논문지
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• 제10권1호
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• pp.113-124
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• 2005

세균검사실의 검사업무는 균종 및 검사종류가 다양하고 최소시간에 검사결과를 도출해야 하므로 업무내용이 복잡하다. 이러한 문제를 해결하기 위하여 에이전트를 이용하여 세균검사에 스케줄링 시스템을 구현하였고, 스케줄링을 관리하는 워크플로우 관리 시스템을 도입하였다. 스케줄링 체크를 위한 쿼리들은 조회가 가능하도록 궈리 시스템을 구현하였다. 그리고 세균검사의 중간 리포트나 결과리포트를 자동으로 보고할 수 있게 하였다. 구현된 스케줄링 시스템은 자원의 낭비나 부족을 파악하고 효율적인 자원할당 및 관리를 할 수 있었다. 궈리 시스템은 스케줄링 체크와 세균검사의 진척상황을 짧은 응답시간에 조회할 수 있었구 리포트의 자동보고 및 근거리나 원거리에서의 조회가 가능하고, 확인과정으로 인한 검사업무의 지연이나 방해요소를 줄일 수 있었다. 또한 검사기기의 오류나 배지, 시약의 부족 등 예측치 못한 예외사항에 대해 검사의뢰자가 확인할 수 있기 때문에 예외사항으로 발생할 수 있는 인간관계의 갈등 요소를 해결할 수 있었고, 작업진행의 효율화를 기대할 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.759-765
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• 2016

Background: Breast cancer is the most frequent cancer of women in Pakistan with the majority presenting with stage III or IV lesionsat initial diagnosis. Patient and health system related factors are well known determinants of delay in presentation and diagnosis. Additionally, breast cancer being a heterogeneous disease, the various molecular subtypes featuring different aggressiveness also need to be considered. The present study evaluated the association of stage at initial diagnosis of breast cancer with these two factors in local women at a tertiary level health care facility in Lahore, Pakistan. Materials and Methods: Patient and tumor features were recorded separately during diagnostic workup in Breast Clinics at INMOL and at Services Hospital, Lahore. Data were entered in MS Excel and analyzed by descriptive statistics and Chi-Square test. Results: Among the 261 patients, 64% were staged as late breast cancer (LBC), the mean age was 46.8 with standard deviation of 13 years. Some 92% had invasive ductal carcinoma (IDC), 61% had luminal types (LT) of non-aggressive tumor while 39% had the non-luminal types (NLT) of of HER2-enriched or basal aggressive tumors. While 70% of patients presented within one year of symptomatic disease (early report group "ERG"), 30% reported after a mean delay of 4 years with a standard deviation of 3.75 years. The stage distribution among ERG patients was not statistically different from those reporting late (P=0.123). Statistically larger proportion of patients with NLT presented as LBC as compared to the LT (P =0.034). Among the ERG, statistically different stage distribution of disease was observed for the NLT versus LT (P=0.047). Among those presenting late, this difference was insignificant (P=0.416). Conclusions: Breast cancer is a distinct disease in Pakistan with a high frequency of aggressive molecular types affecting younger women, with the majority presenting as LBC. Association of NLT with higher stage at diagnosis is statistically significant whereas time delay in diagnosis is not. Further research is required to define the risk profile and features in local patients. The burden of LBC can be reduced by promoting breast health awareness and by establishing easily accessible dedicated breast care set ups in the hospitals.

• Clinical and Experimental Pediatrics
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• 제59권sup1호
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• pp.25-28
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• 2016

Phelan-McDermid syndrome is a rare genetic disorder caused by the terminal or interstitial deletion of the chromosome 22q13.3. Patients with this syndrome usually have global developmental delay, hypotonia, and speech delays. Several putative genes such as the SHANK3, RAB, RABL2B, and IB2 are responsible for the neurological features. This study describes the clinical features and outcomes of Korean patients with Phelan-McDermid syndrome. Two patients showing global developmental delay, hypotonia, and speech delay were diagnosed with Phelan-McDermid syndrome via chromosome analysis, fluorescent in situ hybridization, and multiplex ligation-dependent probe amplification analysis. Brain magnetic resonance imaging of Patients 1 and 2 showed delayed myelination and severe communicating hydrocephalus, respectively. Electroencephalography in patient 2 showed high amplitude spike discharges from the left frontotemporoparietal area, but neither patient developed seizures. Kidney ultrasonography of both the patients revealed multicystic kidney disease and pelviectasis, respectively. Patient 2 experienced recurrent respiratory infections, and chest computed tomography findings demonstrated laryngotracheomalacia and bronchial narrowing. He subsequently died because of heart failure after a ventriculoperitoneal shunt operation at 5 months of age. Patient 1, who is currently 20 months old, has been undergoing rehabilitation therapy. However, global developmental delay was noted, as determines using the Korean Infant and Child Development test, the Denver developmental test, and the Bayley developmental test. This report describes the clinical features, outcomes, and molecular genetic characteristics of two Korean patients with Phelan-McDermid syndrome.

• 대한소아신경학회지
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• 제26권4호
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• pp.272-275
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• 2018

KBG 증후군은 특징적인 얼굴 기형 및 발달 장애, 저 신장 등을 보이는 희귀한 질환이며, ANKRD11유전자의 변이가 KBG 증후군을 일으킨다고 알려져 있다. 그 임상 양상의 스펙트럼은 넓은 편이며, 발달 장애와 신경학적 이상의 경우 개인마다 다양한 정도로 보고되고 있다. 본 증례의 환자들 역시 서로 다른 정도의 발달 장애를 보였으며, 그 중 더 심한 정도의 발달 장애를 가진 환자에서는 뇌전증이 동반되었다. 기존의 KBG증후군의 진단 기준에서 macrodontia는 매우 중요한 요소였으며, 대부분의 KBG 증후군 환자에서 나타난다고 보고되었다. 본 증례의 환자들은 발달장애를 보여 시행한 diagnostic exome sequencing을 통해 ANKRD11 유전자 이상을 확인하였지만 macrodontia는 관찰되지 않았다. 이는 KBG 증후군이 현재까지 밝혀진 것 보다 더 흔할 수 있으며, 특징적인 얼굴 기형이 없는 경우에도 발달장애가 있는 환자들에서는 더욱 적극적인 유전자 검사를 시행하여 KBG 증후군을 진단 할 필요가 있음을 시사한다.

• Imaging Science in Dentistry
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• 제34권1호
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• pp.55-59
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• 2004

Cleidocranial dysplasia is a rare and autosomal dominent disorder characterized by aplasia or hypoplasia of the clavicles, an open fontanelle, dental abnormalities, and short stature, A 17-year-old female who presented with short stature and subsequent delay in eruption of permanent teeth is described. she showed the abnormal hypermobility of the shoulder, ocular hypertelorism and concave nasal bridge. Radiographs revealed the underdeveloped maxilla, defect of the cranium in the fontanelle region, and aplasia of the clavicles. Characteristically, panoramic view revealed near parallel-sided borders of the ascending ramus and downward curvature of the zygomatic arch with hypoplasia. The prolonged retention of deciduous teeth with delayed eruption of permanent teeth and multiple embedded supernumerary teeth were striking. Radiographic and clinical investigations revealed Cleidocranial dysplasia.

• 로봇학회논문지
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• 제3권3호
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• pp.237-244
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• 2008

Nowadays, research on human-robot interaction has been getting increasing attention. In the research field of human-robot interaction, speech signal processing in particular is the source of much interest. In this paper, we report a speaker localization system with six microphones for a humanoid robot called MAHRU from KIST and propose a time delay of arrival (TDOA)-based feature matrix with its algorithm based on the minimum sum of absolute errors (MSAE) for sound source localization. The TDOA-based feature matrix is defined as a simple database matrix calculated from pairs of microphones installed on a humanoid robot. The proposed method, using the TDOA-based feature matrix and its algorithm based on MSAE, effortlessly localizes a sound source without any requirement for calculating approximate nonlinear equations. To verify the solid performance of our speaker localization system for a humanoid robot, we present various experimental results for the speech sources at all directions within 5 m distance and the height divided into three parts.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권2호
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• pp.550-565
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• 2018

Cognitive radio technology is still the key technology of future mobile communication systems. Previous studies have focused on improving spectrum utilization and less energy consumption. In this paper, we propose an Overhead Reduced Scheme (ORS) for green cooperative spectrum sensing. Compared to traditional cooperative sensing scheme, ORS scheme divides the sensing time into three time slots and selects the best multi-mode user to report decisions. In consideration of reporting channel deviation, we derive closed-form expressions for detection probability and false alarm probability of ORS scheme based on Rayleigh fading channel. Simulation results show that ORS scheme can improve the perception accuracy while reducing the perceived delay and energy consumption in the process of perception, so as to realize the green communication.

• Journal of Chest Surgery
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• 제23권1호
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• pp.174-177
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• 1990

Aortic dissection is a challenging disease and the causes of that are well-known. Blunt chest trauma is one of the causes of aortic dissection. In such cases, nearly all cases involves the isthmic portion of descending aorta, but ascending aorta is involved in about 10. We experienced a patient who had ascending aortic dissection due to automobile accident and who showed spontaneous rupture of the aorta during operation. In this case, after installation of aortic line via left femoral artery, ascending aorta ruptured and a large amount of blood gushed out, which was suckered by cardiotomy sucker. A little delay of cardiopulmonary bypass may cause the fatal outcome in such a case because the bleeding from aorta is too much to be controlled. Fortunately, we controlled the bleeding with cardiopulmonary bypass and got the good outcome of this patient by interpositioning the vascular graft. One should suspect the possibility of aortic dissection in blunt chest trauma, and prepare all the facilities against bleeding due to rupture.

• Journal of Korean Neurosurgical Society
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• 제41권3호
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• pp.186-189
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• 2007

Metastasizing mixed tumors [MMT] of salivary glands are inexplicably metastasize maintaining benign histology. There is no pathologic and flow cytometric analysis criteria to predict the metastasis. MMT is known to metastasize by local implantation, vascular and lymphatic embolization after multiple surgery to local recurrences of primary tumor. However, multiple metastasis including cranium and spine occurred even without surgery to the primary tumor in this case. No pathological evidence of malignancy could be found in both primary and metastatic tumor. MMT is considered as an low grade malignancy based on clinical behavior rather than histologic evidence, such as low mortality rate, long delay of metastasis after primary lesion. Cranial metastasis is also extremely rare and only two cases have been reported. We report this unusual case with a literature review.