• Journal of Biomedical Engineering Research
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• v.28 no.6
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• pp.791-797
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• 2007

This paper proposes a semiautomatic vertebra segmentation method that overcomes limitations of both manual segmentation requiring tedious user interactions and fully automatic segmentation that is sensitive to initial conditions. The proposed method extracts fence surfaces between vertebrae, and segments a vertebra using fence-limited region growing. A fence surface is generated by a deformable model utilizing valley information in a valley emphasized Gaussian image. Fence-limited region growing segments a vertebra using gray value homogeneity and fence surfaces acting as barriers. The proposed method has been applied to ten patient data sets, and produced promising results accurately and efficiently with minimal user interaction.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.780-785
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• 2007

Accurate and fast haptic simulations of deformable objects are desired in many applications such as medical virtual reality. In haptic interactions with a coarse model, the number of nodes near the haptic interaction region is too few to generate detailed deformation. Thus, local refinement techniques need to be developed. Many approaches have employed purely geometric subdivision schemes, but they are not proper in describing the deformation behavior of deformable objects. This paper presents a continuum mechanics-based finite element adaptive method to perform haptic interaction with a deformable object. This method superimposes a local fine mesh upon a global coarse model, which consists of the entire deformable object. The local mesh and the global mesh are coupled by the s-version finite element method (s-FEM), which is generally used to enhance accurate solutions near the target points even more. The s-FEM can demonstrate a reliable deformation to users in real-time.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.8
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• pp.1477-1481
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• 2010

In this paper, we propose the classification and tracking method of the hand region using deformable template and condensation. To do this, first, we extract the hand region by using the fuzzy color filter and HCbCr color model. Second, we extract the edge of hand by applying the Canny edge algorithm. Third, we find the first template by calculating the conditional probability between the extracted edge and the model edge. If the accurate template of the first object is decided, the condensation algorithm tries to track it. Finally, we demonstrate the effectiveness and feasibility of the proposed method through some experiments.

• Proceedings of the KIEE Conference
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• 2005.10b
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• pp.3-5
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• 2005

Vessel boundary detection and modeling is a difficult but a necessary task in analyzing the mechanics of inflammation and the structure of the microvasculature. In this paper we present a method of analyzing the structure by means of an active contour model(using GVF Snake) for vessel boundary detection and 3D reconstruction. For this purpose we used a virtual vessel model and produced a phantom model. From these phantom images we obtained the contours of the vessel by GVF Snake and then reconstructed a 3D structure by using the coordinates of snakes.

• Journal of KIISE:Computer Systems and Theory
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• v.29 no.11
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• pp.589-600
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• 2002

Deformable models offer an attractive approach for extracting three-dimensional boundary structures from volumetric images. However, conventional deformable models have three major limitations - sensitive to initial condition, difficult to represent complex boundaries with severe object concavities and protrusions, and self-intersective between model elements. This paper proposes a deformable model that is effective to extract geometrically complex boundary surfaces by improving away the limitations of conventional deformable models. First, the proposed deformable model resamples its elements hierarchically based on volume image pyramid. The hierarchical resampling overcomes sensitivity to initialization by extracting the boundaries of objects in a multiscale scheme and enhances geometric flexibility to be well adapted to complex image features by refining and regularizing the size of model elements based on voxel size. Second, the physics-based formulation of our model integrates conventional internal and external forces, as well as a non-self-intersecting force. The non-self-intersecting force effectively prevents collision or crossing over between non-neighboring model elements by pushing each other apart if they are closer than a limited distance. We show that the proposed model successively extracts the complex boundaries including severe concavities and protrusions, neither depending on initial position nor causing self-intersection, through the experiments on several computer-generated volume images and brain MR volume images.

• Journal of Pharmaceutical Investigation
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• v.34 no.6
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• pp.483-489
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• 2004

Fexofenadine HCl is non-sedating histamine H1 receptor antagonist that can be used for the treatment of seasonal allergic rhinitis. The objective of this study was to investigate whether the carriers of deformable liposomes can enhance the transepithelial permeability of fexofenadine HCl across the in vitro ALI human nasal monolayer model. Characterization of this model was achieved by bioelectric measurements and morphological studies. The passage 2 and 3 of cell monolayers exhibited the TEER value of $2852\;{\pm}\;482\;ohm\;{\times}\;cm^2$ on 11 days of seeding and maintained high TEER value for 5 days. The deformable liposome of fexofenadine HCl was prepared with phosphatidylcholine (PC) and cholic acid using extruder method. The mean particle size was about 200 nm and the maximum entrapment efficiency of 33.0% was obtained in the formulation of 1% PC and $100\;{\mu}g/ml$ fexofenadine HCl. The toxicity of the deformable liposome to human nasal monolayers was evaluated by MTT assay and TEER value change. MTT assay showed that it has no toxic effect on the nasal epithelial cells in 2-hour incubation when the PC concentration was below 1%. However, deformable liposome could not enhance the transepithelial permeability $(P_{app})$ and cellular uptake of fexofenadine HCl. In conclusion, the in vitro model could be used in nasal drug transport studies and evaluation of transepithelial permeability of formulations.

• Advances in concrete construction
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• v.15 no.5
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• pp.349-358
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• 2023

Aim of this work is investigating effect of thickness-stretching formulation on the quasi three-dimensional analysis of micro plate based on a thickness-stretched and shear deformable model through principle of virtual work and micro-scale dependent constitutive relations. Governing differential equations are derived in terms of five unknown functions and the analytical solution is derived using Navier's technique. To explore effect of thickness stretching model on the static results, a comparison between the results with and without thickness stretching effect is presented.

• Journal of Korean Association for Spatial Structures
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• v.5 no.3 s.17
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• pp.65-74
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• 2005

An analytical model was developed to investigate the flexural behavior of a pultruded fiber-reinforced plastic deck of rectangular unit module. The model is based on first-order shea. deformable plate theory (FSDT), and capable of predicting deflection of the deck of arbitrary laminate stacking sequences. To formulate tile problem, two-dimensional plate finite element method is employed. Numerical results are obtained for FRP decks under uniformly-distributed loading, addressing the effects of fiber angle and span-to-height ratio. It is found that the present analytical model is accurate and efficient for solving flexural behavior of FRP decks. Also, as the height of FRP deck plate is higher, the necessity of higher order Shear deformable plate theory(HSDT) is announced, not the FSDT in the plate analysis theory.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.221-224
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• 1996

Since impact phenomenon is highly nonlinear, the analysis and control of the contact motion has been a challenging subject. Various researches have been carried out mostly for the contact of a rigid robotic manipulator with a stiff and elastic environment. This paper is motivated by a new contact task: the in-circuit test of a printed circuit board. In this process, high speed contact occurs between a rigid probing manipulator and a plastically deformable work environment. A new dynamic model of the impact controlled probing task has been proposed, considering contact with the plastically deformable object. Approaching velocity conditions to avoid an excess of the allowable penetration depth and control the generated impact force properly are derived from the proposed model. The results of the simulation studies are made for various probing conditions and show the validity of the proposed model.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.32 no.4
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• pp.362-370
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• 2008

In this paper, we propose a 2D-FE model in single impact with combined physical factors to obtain a unique residual stress by shot peening. Applied physical parameters consist of elastic-plastic deformation of shot ball, material damping coefficients, strain rate, dynamic friction coefficients. As a kinematical parameter, there is impact velocity. Single impact FE model consists of 2D axisymmetric elements. The FE model with combined factors showed converged and unique distributions of surface stress, maximum compressive residual stress and deformation depth. Further, in contrast to the FE models with rigid shot and elastic deformable shot, FE model with plastic deformable shot produces residual stresses very close to experimental solutions by X-ray diffraction. We therefore validated the 2D FE model with combined peening factors and plastic deformable shot. This FE model will be a base of the 3D FE model for residual stresses by multi-impact shot peening.