• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4553-4557
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• 2013

Objective: The purpose of this study was to identify genes related to bladder cancer with samples from normal and disease cases by microarray chip. Methods: After downloading the gene expression profile GSE3167 from Gene Expression Omnibus database which includes 50 bladder samples, comprising 9 normal and 41 disease samples, differentially expressed genes were identified with packages in R language. The selected differentially expressed genes were further analyzed using bioinformatics methods. Firstly, molecular functions, biological processes and cell component analysis were researched by software Gestalt. Then, software String was used to search interaction relationships among differentially expressed genes, and hub genes of the network were selected. Finally, by using plugins of software Cytoscape, Mcode and Bingo, module analysis of hub-genes was performed. Results: A total of 221 genes were identified as differentially expressed by comparing normal and disease bladder samples, and a network as well as the hub gene C1QBP was obtained from the network. The C1QBP module had the closest relationship to production of molecular mediators involved in inflammatory responses. Conclusion: We obtained differentially expressed genes of bladder cancer by microarray, and both PRDX2 and YWHAZ in the module with hub gene C1QBP were most significantly related to production of molecular mediators involved in inflammatory responses. From knowledge of inflammatory responses and cancer, our results showed that, the hub gene and its module could induce inflammation in bladder cancer. These related genes are candidate bio-markers for bladder cancer diagnosis and might be helpful in designing novel therapies.

• Design & Manufacturing
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• 제12권2호
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• pp.27-33
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• 2018

Korea's automobile industry, which has grown rapidly to become the world's fifth-largest automobile producer, To cope with environmental pollution and energy problems in order to prevail competitive edge in global market We are investing a lot of research personnel and costs. Among them, for realizing alternative light weight It is a part of the automobile module system that has achieved the technological development before the breakthrough in the injection molding process in the press process. Door module PNL was the subject of research. The door module PNL is expected to cause warpage before the mold production due to the thin and flat product characteristics and fiber orientation characteristic of the material. In this paper, CAE analysis and reverse correction tool Design. CAE analysis to obtain the results of weld line position, bending position and deformation value Through the correction tool, think3, the original product was modified before the mold production to improve the completeness of the parts. In fiber orientation, the position and size of the cooling channel in the mold, the position and size of the gate, Temperature, pressure, time, and work environment. Compared with the result of CAE analysis, the product that was reverse-corrected by Think3 was manufactured, and injection molding was performed. Injection molding products were tested 24 hours later. 3.5 mm to 7.0 mm, and under the fixed condition, the deviation was from 1.1 mm to 1.5 mm. Unlike the CAE analysis, the deviation of the actual injection pressure and the cooling temperature, the fiber orientation of the material, In order to solve this problem, it is necessary to compare the injection conditions with the database, I knew I had to catch the standard.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.411-414
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• 1997

This paper describes the design guideline, methodology and general specification of the developed 12 channel interpretive electrocardiograph. The developed 12 channel electrocardiograph consists of main module, patient module, DSP module, interface module, power/battery module, TFT color LCD and thermal recorder. The control panel of the system has full keyboard, rotate/push button, function key and unctional indicators. The graphic user interface program conveniently allows user to record, setup, store, manage ECGs. A variety of system configurations give it ability to make user favorable environment. This system also has a resting adult's ECG analysis program. The developed system and program will be continusely evolved using a database of clinically correlated ECGs.

• 한국BIM학회 논문집
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• 제4권1호
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• pp.1-7
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• 2014

The construction method using PC(Precast Concrete) has been widely used because the method can shorten the construction period and improve construction quality. In this paper, through the analysis of present design process for PC railway platform, design parameters on the geometry and properties were extracted and 3D information models for PC railway platform were constructed by the parametric modeling technique. Furthermore, the interface module was developed to link 3D models to the structural analysis/design sheet and database program using VBA(Visual Basic Application). This information model could be used in various areas including structural analysis and design, 2D drawing, quantity estimation and 4D simulation including clash detection.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 1999년도 Proceedings of International Symposium on Remote Sensing
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• pp.63-69
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• 1999

The purpose of this study is to develop Water Quality Management System(WQMS), which performs calculating pollutant discharge and forecasting water quality with water pollution model. Operational water quality management requires not only controlling pollutants but acquiring and managing exact information. A GIS software, ArcView was used to enter or edit geographic data and attribute data, and MapObject was used to customize the user interface. PCI, a remote sensing software, was used for deriving land cover classification from 20 m resolution SPOT data by image processing. WQMS has two subsystems, Database Subsystem and Modelling subsystem. Database subsystem consisted of watershed data from digital map, remote sensing data, government reports, census data and so on. Modelling subsystem consisted of NSPLM(NonStorm Pollutant Load Model)-SPLM(Storm Pollutant Load Model). It calculates the amount of pollutant and predicts water quality. This two subsystem was connected through graphic display module. This system has been calibrated and verified by applying to Mokhyun stream watershed.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 D
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• pp.2741-2743
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• 2005

In this paper, Elevator is designed for real time security & management. Security & Management System is designed for wireless communication between an Elevator and an manager, between Elevation and an manager. Also, to have remote control capability, embedded system platform with TCP/IP techniques are applied to process control system with independent open structure for the precise data transmission and without constraint of operating system. Security and Management system is designed to solve problem of network port by Bluetooth module. Moved recording, unworked table, life of device and replacement time of device are made database, database is applied to Fuzzy Rule for pre-detection unworked Elevator. Security & Management system is designed safety and convenience for customers using Elevator as well as rapidly treatment with unworked Elevator.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1993년도 한국자동제어학술회의논문집(국내학술편); Seoul National University, Seoul; 20-22 Oct. 1993
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• pp.970-974
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• 1993

This paper is concerned with an automatic generation of BOM (Bill Of Material) for a bicycle frame set using a knowledge based system. The major components module system includes : (1) Part information retrieval in CAD drawing, (2) BOM code generation rule, and (3) Database interface. The knowledge based system includes a rule base and a fact base. The fact base consists of basic, variant, and optional components of the standard BOMs of frame sets. The rule contains rules for generating new BOM code in case that the specified is not in the database. The system was implemented on a SUN workstation under Open Windows environments. AutoCAD for CAD drawing was also used.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2000년도 추계학술대회 논문집
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• pp.199-202
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• 2000

In this paper, we developed an expert system that helped a machine-tool designer to select a moderate servomotor of the feed drive unit of a machine tool. With the specification of the drive unit, it searches for the set of servo-motors that have enough torque and power to satisfy the driving condition which the designer defines from the database. me database also contains knowledge and rules, which describe the design process and calculate design parameters of a feed drive. The knowledge-based design support module shows every steps of inference and reason for the solution that it provides.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2003년도 가을 학술발표회 논문집
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• pp.152-155
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• 2003

The design process of concrete retaining walls includes multiple procedures such as structural analysis, member design, the production of calculation sheets, CAD, and itemized statements of Quantities and costs. The objective of this study is to develope an integrated design system that includes all the steps needed for concrete retaining wall design, and as a result, to improve the quality and efficiency of the design process. In this study, the design steps are divided into structural modules and database, and each module and database is systematically combined for the complete design process. The developed design system is based on Web environment. Therefore it can be used in real time and reduces the design work time and space.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2001년도 춘계학술대회 논문집
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• pp.367-372
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• 2001

Feature restoration is that restore feature to 3D solid model using the feature information in STEP AP224. Feature is very important in CAPP, but feature information is defined very complicated in STEP AP224. This paper recommends the algorithm of extraction the feature information in physical STEP AP224file. This program import STEP AP224 file, parse the geometric and topological information, the tolerance data, and feature information line-by-line. After importation and parsing, store data into database. Feature restoration module analyze database including feature information, extract feature information, e.g. feature type, feature's parameter, etc., analyze the relationship and then restore feature to 3D solid model.