• Journal of Pharmaceutical Investigation
• /
• 제9권2호
• /
• pp.1-10
• /
• 1979

The purpose of this paper was to investigate the bioavailability of oxytetracycline in pathological rats and rabbits pretreated with carbon tetrachloride and mercuric chloride. The results are as follows: The blood level of oxytetracycline administered orally was mostly decreased significantly in rabbits damaged kidney and liver, and in rabbits severely damaged kidney, the blood level of oxytetracycline was not significant at 4 to 6 hours. Urinary clearance of oxytetracycline in rabbits severely damaged kidney was inhibited at 5 to 6 hours but in rabbits damaged liver. Hepatic clearance of oxytetracycline was accelerated in rabbits damaged kidney but in rabbits damaged liver. AUC of oxytetracycline orally administered in rabbits damaged liver and kidney was largely decreased. The absorption of oxytetracycline was decreased in rats damaged liver and kidney as compared with that of normal rats. Especially, absorption of oxytetracycline in rats damaged liver was more decreased than that of rats damaged kidney. The absorption of oxytetracycline was inhibited by combinated administration of carbon tetrachloride and mercuric chloride.

• Journal of Pharmaceutical Investigation
• /
• 제8권3호
• /
• pp.1-10
• /
• 1978

The purpose of this paper was to investigate the bioavailability of sulfadimethoxine in pathological rats and rabbits pretreated with carbon tetrachloride and mercuric chloride. The results are as follows: The absorption of sulfadimethoxine was decreased in rats damaged liver and kidney as compared with that of normal rats. Especially, absorption of sulfadimethoxine in rats damaged liver was more decreased than that of rats damaged kidney. Blood level of sulfadimethoxine administered orally was mostly decreased significantly in rabbits damaged kidney and liver, and in rabbits severely damaged kidney the blood level of sulfadimethoxine was not significant at 4 to 6 hours. Urinary clearance of sulfadimethoxine in rabbits severely damaged kidney was inhibited at 5 to 6 hours. but in rabbit damaged liver. Hepatic clearance of sulfadimethoxine was accelerated in rabbits damaged kidney but in rabbits damaged liver. Protein binding percentage of sulfadimethoxine was not affected by the various concentration of carbon tetrachloride and mercuric chloride respectively.

• 대한물리치료과학회지
• /
• 제5권4호
• /
• pp.785-794
• /
• 1998

We have made a survey of 40 patients in the university hospitals and oriental medical centers in Seoul from Sep. 1, 1997 to Mar. 1, 1998. We sampled 25 of them and the result shows that there were 12 MCA damaged patients(48%), 5 SAH(20%), 5 ACA(20%), 2 PCA (8%), 1 PCOA(4%). The number of MCA patients were the most. 1. As the cause of each disease, 4 of the 12 MCA damaged patients(33.35%) have infarction and cerebral hemorrhage, 2 of 5 SAH patients(40%) have cerebral hemorrhage and head injury, 3 ACA damaged patients have cerebral hemorrhage. 11 of 25 brain bloodvessel damaged patients(44%) were hemorrhage patients. 2. Rt. hemiparesis was the main symptom of 6 of 12 MCA damaged patients(50%) and 3 of 5 SAH patients(60%), and the main symptom of 3 of 5 ACA patients(60%) was Lt. hemiparesis. The main symptom of 13 of 25 brain bloodvessel damaged patients(52%) was Lt. hemiparesis 11 of them(44%) Rt. hemiparesis, and 1 of them(8.3%) Quadriplegia. 3. Language was the most well preserved function. 12 MCA damaged patients could understand language. 4. Retraction of shoulder girdle, among VIE flexor synergy, was the most frequent element because 9 of 12 MCA damaged patients had it. Among VIE flexor synergy, 5 SAH patient's most frequent synergy was Elbow flexion because all of them had it. All of 5 ACA damaged patients have shoulder girdle elevation, shoulder joint, hyperextension, abduction, and external rotation among VIE flexor synergy. 5. 7 of 12 MCA damaged patients(58.3%) were stereognosis handicapped patients, 3 of 5 SAH patients(60%) have handicap of position sense, light touch, and temperature, 3 of 5 ACA patients(60%) have position handicap. 13 of brain bloodvessel damaged patients(52%) have light touch handicap. 6. 8 of MCA damaged patients(66.7%) have facial palsy, 4 of SAH damaged patients(80%) have memory and action decline, and 3 of ACA damaged patients(60%) have action decline and facial palsy. The problem of Hemiplegia is very extensive from muscle weakness, atrophy, or deformation to psychical problems. Therefore physical therapists should have sufficient interest in psychological handicap as well as physical handicap as they deal with adult hemiplegia.

• 한국공작기계학회논문집
• /
• 제16권5호
• /
• pp.77-83
• /
• 2007

The study on damaged layer is necessary for machinability improvement in micro machining. The damaged layer in metal cutting is derived from plastic deformation and transformation of metal structure. The damaged layer affects micro mold life and micro machine parts. In this study, the damaged layer of micro machined surface of copper is evaluated according to various machining condition. The damaged layer structure and metallurgical characteristics are measured by optical microscope, and evaluated by cutting forces and surface roughness. The scale of this damaged layer depends on cutting process parameters and machining environments. By experimental results, depth of damaged layer was increased with increasing of cutting depth, also the damaged layer is less occurred in down-milling compared to up-milling during micro endmilling operation.

• 약학회지
• /
• 제22권4호
• /
• pp.226-232
• /
• 1978

It was to investigate the absorption, excretion, protein binding of ampicillin in the pathological animals pretreated with carbon tetrachloride and mercuric chloride. The absorption of ampicillin was not affected in rats with damaged liver and kidney as compared with that of normal rats. The blood level of ampicillin after oral administration was increased significantly in rabbits with damaged kidney and liver. The blood level of ampicillin in rabbit with damaged kidney was more increased than that in rabbits with damaged liver. In severly damaged rabbits, it was more increased than that of mildly damaged rabbits. Urinary excretion of ampicillin in pathological animals was more inhibited than that of ampicillin in normals. Hepatic excretion of ampicillin was accelerated in rabbits with damaged kidney. However, in rabbits with damaged liver, it was inhibited as compared with that in normals. Protein binding of ampicillin was slightly enhanced by the various concentration of carbon tetrachloride and mercuric chloride, respectively. The results suggest that the increase of blood level of ampicillin in pathological animals was due to the inhibition of renal excretion.

• 한국태양에너지학회 논문집
• /
• 제35권4호
• /
• pp.67-75
• /
• 2015

PV module is conventionally connected in series with some solar cell to adjust the output of module. Some bypass diodes in module are installed to prevent module from hot spot and mismatch power loss. However, bypass diode in module exposed outdoor is easily damaged by surge voltage. In this paper, we study the thermal and electrical characteristics change of module with damaged bypass diode to easily find module with damaged bypass diode in photovoltaic system consisting of many modules. Firstly, the temperature change of bypass diode is measured according to forward and reverse bias current flowing through bypass diode. The maximum surface temperature of damaged bypass diode applied reverse bias is higher than that of normal bypass diode despite flowing equal current. Also, the output change of module with and without damaged bypass diode is observed. The output of module with damaged bypass diode is proportionally reduced by the total number of connected solar cells per one bypass diode. Lastly, the distribution temperature of module with damaged bypass diode is confirmed by IR camera. Temperature of all solar cells connected with damaged bypass diode rises and even hot spot of some solar cells is observed. We confirm that damaged bypass diodes in module lead to power drop of module, temperature rise of module and temperature rise of bypass diode. Those results are used to find module with a damaged bypass diode in system.

• KSBB Journal
• /
• 제28권3호
• /
• pp.191-195
• /
• 2013

Cordyceps militaris (CM) occurring from a fruiting body by a host insect is a kind of mushroom, which is composed of animal host and plant fruit body. CM contains large amounts of useful ingredients including polysaccharides, vitamins, amino acids, minerals, etc. The essential amino acids from CM including cystine, lysine, and methionine can be expected to improve damaged hair treatment as effective ingredients. In this study, the improvement effect of the CM extracts on chemical and physical properties for damaged-hair treatment was investigated. The cysteic acid and cystine monooxide produced by oxidation of cystine were analyzed their chemical structure by FT-IR spectroscopy. It was confirmed that the vibration absorption peak ($1,041cm^{-1}$) of cysteic acid was reduced and increased sulfur content considerably which means meaningful improvement effect on damaged-hair treatment. Apparently, the cuticle morphology of the damaged-hair was improved significantly by treatment with CM extracts. Especially, confocal laser scanning microscope images of the damaged-hair treated with the extract showed highly increased fluorescence intensity which means promising effect in hair treatment. The tensile strength of the damaged hair treated also increased by 168% compared with the damaged hair.

• 대한원격탐사학회:학술대회논문집
• /
• 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
• /
• pp.533-536
• /
• 2007

The LiDAR data structure has the potential for modeling in three dimensions because the LiDAR data can represent voxels with z value under certain defined conditions. Therefore, it is possible to classify the physical damaged degree of vegetation by forest fire as using the LiDAR data because the physical loss of canopy height and width by forest fire can be relative to an amount of points reached to the ground through the canopy of damaged forest. On the other hand, biological damage of vegetation by forest fire can be explained using the NDVI (Normalized Difference Vegetation Index) which show vegetation vitality. In this study, we graded the damaged degree of vegetation by forest fire in Yangyang-Gun of South Korea using the LiDAR data for physical grading and digital aerial photograph including Red, Green, Blue and Near Infra-Red bands for biological grading. The LiDAR data was classified into 2 classes, of which one was Serious Physical Damaged (SPD) and the other was Light Physical Damaged (LPD) area. The NDVI was also classified into 2 classes which are Serious Biological Damaged (SBD) and Light Biological Damaged (LBD) area respectively. With each 2 classes ofthe LiDAR data and NDVI, the damaged area by forest fire was graded into 4 degrees like damaged class 1,2,3 and 4 grade. As a result of this study, 1 graded area was the broadest and next was the 3 grade. With this result, we could know that the burned area by forest fire in Yangyang-Gun was damaged rather biologically because the NDVI in 1 and 3 grade appeared low value whereas the LiDAR data in 1 and 3 grade included light physical damage like the LPD.

• 한국육종학회지
• /
• 제42권5호
• /
• pp.439-447
• /
• 2010

Riptortus clavatus, one of the many insects in major crops, damages pods and seeds, which reduces seed vigor and viability in soybeans. This study was conducted to examine the effect of diversely damaged seeds by R. clavatus on seed germination and seedling emergence and to determine the association of damaged seed with quality and yield of soybean sprouts. All seeds damaged by R. clavatus significantly (P<0.05) reduced seed vigor as measured by the rates of seed germination, germination speed, and seedling emergence. Mean seed germination rate of non-damaged seeds in sprout-soybean varieties was 97.8%, whereas the rates of seeds damaged at different levels, 31-50% and 51-80%, were 23.0 and 5.4%, respectively. The rates of seedling rot and abnormal, incomplete germination significantly (P<0.05) increased as the amount of seeds damaged by R. clavatus increased to 5, 10 and 15% against the total seeds for sprout production. Yield of soybean sprouts from seeds damaged at different levels decreased up to 13% as compared to that in normal seeds. In customer preferences on soybean sprout produce, 84% of customers participated in survey preferred to purchase sprouts from seeds with 5% of damaged seeds, but sprouts produced from seeds with 15% of damaged seeds were intended to purchase only by 22% of the customers. Areas of the seed damaged by R. clavatus were readily infected by pathogens as the seed germinated, resulted in deteriorated quality and reduced yield of sprout produce.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 1997년도 추계학술대회 논문집
• /
• pp.981-984
• /
• 1997

This paper deals with the relation of cutting conditions and damaged layer by investigating cutting force, cutting temperature and residual stress in high speed machining. Damaged layer was measured using optical microscope on samples prepared by metallographic techniques. The scale of this damaged layer depends upon characteristics of cutting force and cutting temperature. Damaged layer depth increases with feed per tooth and radial depth. In a different another way, damaged layer remains almost unchanged according to spindle speed. Therefore, the effective method for decreasing damaged layer is that cut down feed per tooth and radial depth.