• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.19 no.1
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• pp.161-170
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• 2019

Multi-product mass production small and medium enterprise factories have a wide variety of products and a large number of products, wasting manpower and expenses for inventory management. In addition, there is no way to check the status of inventory in real time, and it is suffering economic damage due to excess inventory and shortage of stock. There are many ways to build a real-time data collection environment, but most of them are difficult to afford for small and medium-sized companies. Therefore, smart factories of small and medium enterprises are faced with difficult reality and it is hard to find appropriate countermeasures. In this paper, we implemented the contents of extension of existing inventory management method through character extraction on label with barcode and QR code, which are widely adopted as current product management technology, and evaluated the effect. Technically, through preprocessing using OpenCV for automatic recognition and classification of stock labels and barcodes, which is a method for managing input and output of existing products through computer image processing, and OCR (Optical Character Recognition) function of Google vision API. And it is designed to recognize the barcode through Zbar. We propose a method to manage inventory by real-time image recognition through Raspberry Pi without using expensive equipment.

• Biomolecules & Therapeutics
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• v.29 no.6
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• pp.685-696
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• 2021

In this study, we investigated the inhibitory effect of 5-aminolevulinic acid (ALA), a heme precursor, on inflammatory and oxidative stress activated by lipopolysaccharide (LPS) in RAW 264.7 macrophages by estimating nitric oxide (NO), prostaglandin E2 (PGE2), cytokines, and reactive oxygen species (ROS). We also evaluated the molecular mechanisms through analysis of the expression of their regulatory genes, and further evaluated the anti-inflammatory and antioxidant efficacy of ALA against LPS in the zebrafish model. Our results indicated that ALA treatment significantly attenuated the LPS-induced release of pro-inflammatory mediators including NO and PGE2, which was associated with decreased inducible NO synthase and cyclooxygenase-2 expression. ALA also inhibited the LPS-induced expression of pro-inflammatory cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6, reducing their extracellular secretion. Additionally, ALA abolished ROS generation, improved the mitochondrial mass, and enhanced the expression of heme oxygenase-1 (HO-1) and the activation of nuclear translocation of nuclear factor-E2-related factor 2 (Nrf2) in LPS-stimulated RAW 264.7 macrophages. However, zinc protoporphyrin, a specific inhibitor of HO-1, reversed the ALA-mediated inhibition of pro-inflammatory cytokines production and activation of mitochondrial function in LPS-treated RAW 264.7 macrophages. Furthermore, ALA significantly abolished the expression of LPS-induced pro-inflammatory mediators and cytokines, and showed strong protective effects against NO and ROS production in zebrafish larvae. In conclusion, our findings suggest that ALA exerts LPS-induced anti-inflammatory and antioxidant effects by upregulating the Nrf2/HO-1 signaling pathway, and that ALA can be a potential functional agent to prevent inflammatory and oxidative damage.

• Journal of Life Science
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• v.31 no.2
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• pp.237-247
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• 2021

Immune responses in the central nervous system (CNS) function as the host's defense system against pathogens and usually help with repair and regeneration. However, chronic and exaggerated neuroinflammation is detrimental and may create neuronal damage in many cases. The NOD-, LRR-, and pyrin domain―containing 3 (NLRP3) inflammasome, a kind of NOD-like receptor, is a cytosolic multiprotein complex that consists of sensors (NLRP3), adaptors (apoptosis-associated speck like protein containing a caspase recruitment domain, ASC) and effectors (caspase 1). It can detect a broad range of microbial pathogens along with foreign and host-derived danger signals, resulting in the assembly and activation of the NLRP3 inflammasome. Upon activation, NLRP3 inflammasome leads to caspase 1-dependent secretion of the pro-inflammatory cytokines IL-1β and IL-18, as well as to gasdermin D-mediated pyroptotic cell death. NLRP3 inflammasome is highly expressed in CNS-resident cell types, including microglia and astrocytes, and growing evidence suggests that NLRP3 inflammasome is a crucial player in the pathophysiology of several neuroinflammatory and psychiatric diseases, such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, traumatic brain injury, amyotrophic lateral sclerosis, and major depressive disorder. Thus, this review describes the molecular mechanisms of NLRP3 inflammasome activation and its crucial roles in the pathogenesis of neurological disorders.

• Journal of Life Science
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• v.31 no.3
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• pp.338-345
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• 2021

Zizania latifolia has long been used as a tea for both edible and medicinal purposes. However, research into the use of Z. latifolia as a high value-added edible material is lacking. In a previous study, we confirmed that tricin is the major component in Z. latifolia. In this study, we investigated the protective effect of a Z. latifolia extract (ZLE). Toxicity tests of ZLE or tricin on HepG2 cells revealed no toxicity due to ZLE or tricin at all concentrations used. The reduction in cell viability by tert-butyl hydroperoxide (t-BHP) was suppressed by treatment with ZLE or tricin. In addition, ZLE or tricin effectively inhibited the production of reactive oxygen species (generation of hydrogen peroxide, alkoxy free radicals, and peroxyl free radicals by t-BHP) and oxidative damage. ZLE or tricin treatments also increased the protein expression of superoxide dismutase 1 (SOD1), catalase, heme oxygenase-1 (HO-1), and nuclear factor erythroid-related factor 2 (Nrf2), which are known as antioxidant enzymes, suggesting that the protective effect of ZLE is related to activation of tricin. Taken together, the results indicate that Z. latifolia can be developed as a functional food material for improving liver function.

• Journal of the Korean GEO-environmental Society
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• v.22 no.3
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• pp.31-35
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• 2021

The expansion joints installed on the bridge for the accommodation of expansion and contraction of the supper structure are essential members of the bridge. However, the expansion joints are deteriorated over time and the waterproof function weakens, causing rainwater to penetrate and deteriorate the structure. In order to solve the traffic congestion caused by frequent replacement of the old expansion joints along with the deterioration of the structure, a post-integrated abutment bridge in which the existing expansion joints are removed and replaced with reinforced concrete link connection has been applied to highway bridges since 2016. After the post-integrated abutment method was applied, it was partially applied to bridges in which the superstructure and abutment were jammed. In this study, the causes of problems that may occur when the post-integrated abutment method is applied to the jammed bridge were analyzed numerically. It was analyzed that damage occurred in the link connection part. Based on the results of this study, the application condition for the post-integrated abutment method is reinforced as it is not possible to apply the post-integrated abutment method to bridges are already jammed.

• Journal of Korean Physical Therapy Science
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• v.27 no.3
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• pp.45-55
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• 2020

Background: The purpose of this study was to investigate the effects of WBC (whole-body cryotherapy)on the MVIC (maximal voluntary isometric contraction)and active ROM (range of motion) recovery of after EIMD (exercise-induced muscle injury). Design: Randomized Controlled Trial. Methods: Thirty subjects who are student in their 20s at a university participated in this study, these subjects were assigned into three groups, a control group (n=10), experiment group I(n=10), and experiment group II (n=10). The subjects in the experimental group II were intervened by WBC (-130℃, 3 minutes) before induced EIMD, the experimental group were intervened by WBC (-130℃, 3 minutes) after induced EIMD, and the control group weren't by any intervened after induced EIMD. Results: First, In the comparison of the MVIC, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the MVIC of experimental group II was significantly larger than those of other groups (p<.001). Second, In the comparison of the active extension angle, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the active extension angle of experimental group II was significantly smaller than those of other groups (p<.001). Third, In the comparison of the active flexion angle, there were significant variations with the lapse the time in three groups (p<.01) and there was a significant interaction of time and group (p<.001). In the among group comparison, the active flexion angle of experimental group II was significantly larger than those of other groups (p<.05). Conclusion: The above results revealed that the WBC intervention after an exercise had a positive effect of muscle function after EIMD. Therefore we can consider the WBC as a considerable intervention method to prevent or reduce an exercise injury.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.291-298
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• 2021

In this study, the future of countermobility capability is presented by analyzing the status of the countermobility obstacles focusing on the history of landmines and munitions. The conventional landmine was forbidden globally by the CCW and Ottawa Treaty because it caused civilian damage after the war. Because the inhumanity of those mines had been acknowledged, shatterable mines with a self-destruct (SD) function and M93 "HORNET" anti-tank munition with enhanced sensors have been fielded. In 2016, the Obama administration announced a policy that banned all antipersonnel landmines, leaving a considerable gap in the countermobility capability. To deal with these problems, the developments of "SAVO" and the SLEP program of Volcano mines were conducted. In the sense of a long-term approach, the countermobility obstacles, including mines, were chosen as fundamental forces for Multi-Domain Operations and were improved to Terrain Shaping Obstacles (TSO). TSO has improved sensors and mobility kill capabilities and features an enhanced remote control over each munition on the battlefield through a network established with satellite communication. The combined arms countermobility might be fully capable until 2050 if the TSO program can be completed successfully.

• The Journal of the Korea Contents Association
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• v.21 no.1
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• pp.426-433
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• 2021

Investment in public sector information services has been on the rise in recent years. The supply of high-speed Internet and smartphones has become more common, and the stability of the information system provided to the public in the public sector has become an important management factor. In other words, tasks such as handling civil complaints and issuing certificates by public institutions, financial transactions by banks, customs clearance work, and e-commerce by individuals or institutions are mostly done online. Therefore, how to deal with obstacles arising from the information system, which is in charge of important civil service affairs, is becoming a very important issue. In other words, in the case of a disability that does not function normally even for a short period of time, various problems can occur when the work is delayed, as well as causing serious financial damage to the civil petitioner. This could be accompanied by a decline in public confidence and various other damages such as filing civil complaints. The reasons for the occurrence of information system failures are very diverse and realistically difficult to predict when. Among the various measures to cope with disability, this paper proposed a plan to establish a disability situation notification system that can minimize confusion caused by disability in the event of a homepage malfunction. The proposed disability situation notification system was established in the public IDC environment to show the possibility of utilization.

• Journal of the Korean Institute of Gas
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• v.24 no.6
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• pp.47-54
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• 2020

A brittle fracture is one of the source of structural damage and can bring a fatal accident. The inner shell of LNG storage tank should be designed and applied to construction by ensure that no brittle crack will occur under -162℃ condition. In point of view of fracture mechanics brittle fracture in the structure could be referred as crack initiation and crack arrest. It should be designed no crack initiation. However, in the unlikely event of a brittle fracture occurring, a back-up function of arresting the brittle crack should be included for the design. In this paper investigated the characteristics of 9% Ni steel thick plates of having a capability of arresting brittle cracks under the thickness of 33 mm, 37mm, 40 mm. First, charpy test has performed to evaluate the fundamental brittle impact fracture property of 9% Ni steel under the temperature of 24℃, -162℃ and -196℃. In addition, Duplex ESSO tests were also performed under -196℃ to evaluate the capability of crack arrest for 9% Ni steel. From the experiments results, it was confirmed that all the thickness of 9% Ni steel plates exhibits sufficient brittle crack arrest fracture toughness for the application of LNG storage tank as a inner shell.

• Resources Recycling
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• v.30 no.4
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• pp.35-45
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• 2021

The humidity-control function and manufacturing characteristics of wood-wool boards using waste-paper-mulberry fiber were analyzed in this study. For the manufacture of wood-wool boards, the pulverizing times of waste-paper-mulberry fibers were controlled at 30, 60, 120, and 180 s, and the mixing amounts were controlled by adding 0%, 3%, 6%, and 9%, respectively, as compared to cement. Analysis of the moisture adsorption and desorption characteristics of the wood-wool boards controlled for pulverizing time revealed that the wood-wool board with 60 s of pulverized fiber exhibited the best adsorption and desorption performances. It was estimated that the adsorption and desorption performances of the material itself were adequate even when the boards were mixed because of minimal damage to the fiber. In addition, an analysis of the absorption and desorption characteristics of the fiber-mixture-controlled wood-wool boards showed that the 6%-mixed wood-wool board had the best absorption and desorption performances of 291.00 g/m² and 108.75 g/m², respectively.