• 제목/요약/키워드: DON

검색결과 7,650건 처리시간 0.035초

구형과 신형 소방 보호장갑의 착탈 시험 및 동작 기민성 평가를 통한 통합형 착용 시험법 (Integrated Test Method by the Evaluation of Don-doff and Mobility of Old and Newly-developed Firefighting Protective Gloves)

  • 배규태;김도형;신혜영;이주영
    • 한국의류학회지
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    • 제41권5호
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    • pp.950-965
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    • 2017
  • This present study proposed a newly developed test method to evaluate the dexterity and mobility of a firefighter's protective gloves. The first step evaluated the mobility and dexterity of the current type of fire protective gloves and three new types of protective gloves using Don-doff test, ASTM dexterity, Minnesota dexterity, Bennett hand tool test, and ASTM torque test. Three firefighters ($47.3{\pm}5.0yr$ in age, $178.6{\pm}2.9cm$ in height) participated in a series of experiments. The second step was to design and suggest an integrated test method based on the results of the first experiment. As a result of the first experiment, we concluded that 1) the mobility and dexterity tests for firefighting gloves should include both wet and dry tests, 2) The three kinds of dexterity tests could be integrated into one test, and 3) The don-doff test and the torque test should be independent from the newly developed integrated test. In summary, we suggested a simplified test method that combined ASTM dexterity, Minnesota dexterity, and Bennett hand tool test. The integrated system can reduce total time spent on dexterity tests and improve the validity of the test in terms of firefighters' manual work.

Inductions of Caspase-, MAPK- and ROS-dependent Apoptosis and Chemotherapeutic Effects Caused by an Ethanol Extract of Scutellaria barbata D. Don in Human Gastric Adenocarcinoma Cells

  • Shim, Ji Hwan;Gim, Huijin;Lee, Soojin;Kim, Byung Joo
    • 대한약침학회지
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    • 제19권2호
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    • pp.129-136
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    • 2016
  • Objectives: The crude extracts of Scutellaria barbata D. Don (SB) have traditionally demonstrated inhibitory effects on numerous human cancers both in vitro and in vivo. Gastric cancer is one of the most common types of cancer on world. The authors investigated the effects of an ethanol extract of Scutellaria barbata D. Don (ESB) on the growth and survival of MKN-45 cells (a human gastric adenocarcinoma cell line). Methods: The MKN-45 cells were treated with different concentrations of ESB, and cell death was examined using an MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay. Analyses of sub-G1 peaks, caspase-3 and -9 activities, and mitochondrial membrane depolarizations were conducted to determine the anti-cancer effects of SB on MKN-45 cells. Also, intracellular reactive oxygen species (ROS) generation was investigated. Results: ESB inhibited the growth of MKN-45 cells, caused cell cycle arrest, and increased the sub-G1 population. In addition, ESB markedly increased mitochondrial membrane depolarization and the activities of caspase-3 and -9. ESB exerted anti-proliferative effects on MKN-45 cells by modulating the mitogen-activated protein kinase (MAPK) signaling pathway and by increasing the generation of ROS. Furthermore, combinations of anti-cancer drugs plus ESB suppressed cell growth more than treatments with an agent or ESB, and this was especially true for cisplatin, etoposide, and doxorubicin. Conclusion: ESB has a dose-dependent cytotoxic effect on MKN-45 cells and this is closely associated with the induction of apoptosis. ESB-induced apoptosis is mediated by mitochondria-, caspase- and MAPK dependent pathways. In addition, ESB enhances ROS generation and increases the chemosensitivity of MKN-45 cells. These results suggest that treatment with ESB can inhibit the proliferation and promote the apoptosis of human gastric adenocarcinoma cells by modulating the caspase-, MAPK- and ROS-dependent pathway.

가족보건에 대한 지식 및 태도에 관한 조사연구 (일부 지방대학생을 중심으로) (A Study on Knowledge and Attitude of a Group of Regional University Students)

  • 박선섭
    • 보건교육건강증진학회지
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    • 제2권1호
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    • pp.81-92
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    • 1984
  • To find out the amount of knowledge and the attitude which a group of students attending local universities have toward family health, I distributed 690 questionaires to three local universities which I chose. I arrived at the following conculsion after 628 questionnairs were returned. 1) 431 male students(89.8%) and 126 femals students (86.2%) felt that family health science is important enough to be part of the cirriculum. 2) 374 male students (74.5) and 132 female students (90.4%) answered that they get a basic knowledge of health and disease through massmedia. 3) Should an information bureau for health and diseare be retup, 369 students(63.2%) answered that they would join information bureau. 4) In regard to a basic knowledge of health, the report says that 419 ma1e students(83.4%) and 117 female students(80%) don't know about Blood pressure, and 422 male students(84%) and 124 female students (84.9%) don't know about normal pulse and 467 male students(93%) and 128 femal stdents(87.6%) don't know about normal respiration. 5) In regard to communicable disese, 186 male students(37.1%) and 61 female students(41.7%) have a basic knowledge of these disease. In regard to diseases which commonly afflict the eldrly, 157 male students (31.2%) and 62 female students (42.4%) have a basic knowledge of these diseases. In regard to other diseases, the finding of this report are that on the average male students(74.6%) and female students of(73.4%) don't have a basic knowledge of family health. 6) 182 male students (36.2%) and 50 female students (34.2%) anwered that the way to promote health and prevent disease is to have a medical examination regularly and also 142 male students (28.2%) and 33 female students(22.6%) answered that it is necessary to have knowledge about how to keep health. 7) 254 male students (50.4%) and 90 female students (61.6%) said that when they are sick they depend on help from the pharmacist.

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Jasminum attenuatum Roxb. ex G. Don: 베트남 미기록종 (Jasminum attenuatum Roxb. ex G. Don (Oleaceae): a new record to the flora of Vietnam)

  • ;;;이창영;이중구
    • 식물분류학회지
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    • 제43권4호
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    • pp.263-266
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    • 2013
  • 베트남 Kon Ka Kinh 국립공원에서 최근에 발견된 Jasminum attenuatum Roxb. ex G. Don, (물푸레나무과)을 베트남 미기록종으로 보고한다. 본 종은 근연종인 J. latipetalum과 J. simplicifolium subsp. funale와는 엽신의 모양, 화서에 5-20개의 꽃이 달리고 선상의 포를 가지며 악편은 짧고 무모이며 역원추형의 악을 갖는 특징으로 근연종들과 구분된다. 본 연구에 종 동정을 위한 중요한 형질과 분류학적 기재, 식물도해, 원색사진 및 화분의 주사전자현미경 사진을 제시하였으며 본 종과 근연종인 J. latipetalum과 J. simplicifolium subsp. funale 와의 분류학적 형질들을 비교하였다.

기존한약서의 현대적 용량 환산을 위한 도량형의 시대적 변천 고찰 (Historical Changes in Weights and Measures of Herbal Formulas in Medical Classics)

  • 한천희;이수연;김지훈;김윤경
    • 대한한의학방제학회지
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    • 제25권1호
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    • pp.103-113
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    • 2017
  • Objectives : Korea and China are applying different conversion standards for weight in traditional medicine books. This study aims to research and suggest how to convert the units of weight in old traditional medicine classics into the contemporary unit of grams. Methods : Historical documents of Korea and China were used to review the process in which weights and measures changed in each country and the manners in which the Chinese units of weight were introduced to Korea. Results : Weights and measures changed with time. They became almost standardized by the period of Song in China, when coins played the most crucial role, and it was introduced to Korea. Donggaryang, the standard container for weights and measures in ancient China, Gaewontongbo, a coin in Tang, Sangpyeongtongbo, a coin in Joseon, and a scale in Joseon were used as strong foundations for conclusion from literature review. Weight of a 1-don(coin) in the time a traditional medicine books were written was used as a unit of weight in those books. Sangpyeongtongbo, a 1-don coin in Joseon, weighs 4 grams on average. Conclusions : Since the current conversion of 1-don coin into 3.75 grams is not supported by literature review, it is suggested that 1-don(coin) as a unit of weight in traditional medicine books of Joseon, may be better converted into 4 grams, while that of China is converted to 3.73 grams.

채용시 건강진단과 순음청력검사 및 요추부 단순방사선 검사가 근로자 채용에 미치는 영향 - 인천, 경기 지역 2003년 실태 조사 - (The Influence of Preemployment Medical Examination, Pure Tone Audiometry, and Simple Lumbar Spine X-ray Test on the Worker's Employment - The Result of Survey at Incheon Metropolitan City and Gyeonggi Province in Korea, the Year 2003 -)

  • 김경자;한상환;성낙정
    • 한국직업건강간호학회지
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    • 제12권2호
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    • pp.146-155
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    • 2003
  • This study was conducted for investigating the status of management of preemployment health examination and to have an effect on the worker's employment. Health managers of 103 companies in Incheon metropolitan city and Gyeonggi were interviewed by telephone. Of 103 companies, 67(65.1%) said they don't hire the applicants who have an active pulmonary tuberculosis, 80(77.7%) companies said they health HBV carrier is acceptable but active HBV carrier is not 29(28.2%) companies said they don't hire the applicants who have a hypertension or diabetes mellitus, 42(40.8%) companies said they don't hire the applicants who have a hearing disturbance. If HIVD is suspicious in X-ray lumbar-sacral region, 37(78.7% of 47 companies) said they do not hire the applicants. 29(35% of 83 companies) said they cancel the employment of the applicants who are suspicious of noise induced hearing loss on preplacement health examination. From our survey, preemployment health examination was utilizing mainly as a tool for the selection of health employees who don't have a disease. Furthermore, in many companies, additional test items are being included and getting more strict the selection criteria for preemployment health examination. For the right use of preemployment health examination, author suggested that further studies were needed to select the adequate test items and establish the reasonable criteria for preemployment health examination.

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중국으로부터 수입한 옥수수에서의 Fusarium 진균독소오염 (Contamination of Fusarium Mycotoxins in Corn Samples Imported from China)

  • 강효중;김진철;서정아;이인원;손동화
    • Applied Biological Chemistry
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    • 제37권5호
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    • pp.385-391
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    • 1994
  • 중국으로부터 수입한 68개의 옥수수시료에서 Fusarium진균독소의 오염을 조사하였다. 수입옥수수에서 eoxynivalenol(DON), 15-acetyldeoxynivalenol(15-ADON), 3-acetyldeoxynivalenol(3-ADON) 및 nivalenol(NIV) 등 4가지의 8-ketotrichothecene이 검출되었다. 또한 zearalenone(ZEA), fumonisin $B_1(FB_1)$, fumonisin $B_2(FB_2)$ 그리고 fumonisin $B_3(FB_3)$도 검출되었다. DON, 15-ADON, 3-ADON, ZEA 그리고 $FB_1$이 주요 오염독소였으며, 이들 독소의 평균오염농도는 각각 277, 34, 37, 39, 그리고 123 ng/g이었다.

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친환경 소하천의 수리적 안정성 분석에 관한 연구 (A Study on Hydraulic Stable Analysis of The Natural Small River)

  • 김태경;이경훈;선병진;최천호
    • 환경영향평가
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    • 제16권3호
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    • pp.187-194
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    • 2007
  • It started road constructions around river in 1990s. These maintenances concentrate on city river. Because river lives no living things and men don't come near there. But in spite of these river environment go to rack, river maintenances still keep on using preexistence method since 1990s. Only a part of city river environment maintenances consider environmental ability of passive river, river maintenance of a purpose of flood control still don't consider in the concrete. Because propulsion device that consider environment ability of passive river and possible application techniques don't complete. In accordance, A natural river maintenance needs absolutly a series of river projects. Because a natural river maintenance prevents a damage of environment ability. This study is to assume the flood really happened and to carry out the flood damage simulation needed in overflow simulation about the inundated zone. Also, This study examine unstable part about the hydraulic characteristic as velocities, stream power, shear, hydraulic depth, flow area in basin. And this study applied the HEC-RAS(river analysis system) model to predict flood overflow in youngsan river basin. Project flood is used the return period 100 year and inputed data that was calculated in intensity figures of illumination.

열압밀화 라디에타 소나무재의 압축세트량에 따른 역학적 특성 (The Mechanical Properties of Heat-Compressed Radiata Pine (Pinus radiata D.Don) by Compression Set)

  • 황성욱;이원희
    • Journal of the Korean Wood Science and Technology
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    • 제39권4호
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    • pp.311-317
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    • 2011
  • 라디에타 소나무(Pinus radiata D.Don)를 압체온도 $180^{\circ}C$, 압체시간 60분 조건으로 열압밀화 목재를 제작하여 압축세트량에 따른 종압축강도, 휨강도, 경도, 못뽑기저항을 조사하였다. 압축세트량 60%인 열압밀화 목재의 비중은 1.01로 나타났으며, 대조군의 비중 0.48에 비해 현저히 증가한 값을 나타내었다. 압축세트량의 증가와 함께 모든 역학적 특성도 향상되었다. 그리고 라디에타 소나무의 최대 압축세트량은 약 65%로 확인되었으며, 이는 비중 0.48인 라디에타 소나무의 공극율 68%와 거의 일치하는 결과이다.

초등수학의 개별학습을 위한 학습자 진단 시스템의 설계 및 구현 (A Design and Implementation of Learner Diagnosis System of mathematics for Elementary School Students Individualized Learning)

  • 허정원;김갑수
    • 정보교육학회논문지
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    • 제6권1호
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    • pp.1-12
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    • 2002
  • 본 논문은 초등학생의 수학과 학습능력을 진단하여서 결과에 따라 개별학습을 할 수 있는 LED 시스템 (LEarner Diagnosis system)을 설계 구현한 것이다. 수학과와 같이 위계적으로 학습이 이루어지는 교과는 선수학습을 제대로 성취하지 못하면 후속학습에 곤란을 겪는다. 이를 방지하기 위해 LED 시스템은 학습 전에 학습자의 선수 학습 능력을 진단한다. 진단 결과 학습 결손이 있을 때는 보충학습을 통해 결손을 보충하고 본 주제학습을 한다. 또한 매 학습이 완전학습이 되어 더 이상의 학습결손이 발생하지 않도록 학습 후에도 진단평가를 실시하여 완전학습이 이루어졌을때만 후속학습을 할 수 있도록 한다. LED 시스템을 이용하면 학습자는 학습결손을 방지할 수 있고 완전학습을 하기 때문에 궁극적으로 학습 목표에 도달 할 수 있게 된다.

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