• Nuclear Engineering and Technology
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• 제55권6호
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• pp.1949-1958
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• 2023

The International Commission on Radiological Protection (ICRP) Publication 116 was released to provide a comprehensive dataset of the dose coefficients (DCs) for external exposures produced with the adult reference voxel phantoms of ICRP Publication 110. Although an advanced skeletal dosimetry method for photons and neutrons using fluence-to-dose response functions (DRFs) was introduced in ICRP Publication 116, the ICRP-116 skeletal DCs were calculated by using the simple method conventionally used (i.e., doses to red bone marrow and endosteum approximated by doses to spongiosa and/or medullary cavities). In the present study, the photon and neutron DRFs were used to produce skeletal DCs of the ICRP-110 reference phantoms, which were then compared with the ICRP-116 DCs. For photons, there were significant differences by up to ~2.8 times especially at energies <0.3 MeV. For neutrons, the differences were generally small over the entire energy region (mostly <20%). The general impact of the DRF-based skeletal DCs on the effective dose calculations was negligibly small, supporting the validity of the ICRP-116 effective DCs despite their skeletal DCs derived from the simple method. Meanwhile, we believe that the DRF-based skeletal DCs could be beneficial in better estimates of skeletal doses of individuals for risk assessments.

• IMMUNE NETWORK
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• 제16권1호
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• pp.61-74
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• 2016

Dendritic cells (DCs) are professional antigen-presenting cells that sample their environment and present antigens to naïve T lymphocytes for the subsequent antigen-specific immune responses. DCs exist in a range of distinct subpopulations including plasmacytoid DCs (pDCs) and classical DCs (cDCs), with the latter consisting of the cDC1 and cDC2 lineages. Although the roles of DC-specific transcription factors across the DC subsets have become understood, the posttranscriptional mechanisms that regulate DC development are yet to be elucidated. MicroRNAs (miRNAs) are pivotal posttranscriptional regulators of gene expression in a myriad of biological processes, but their contribution to the immune system is just beginning to surface. In this study, our in-house probe collection was screened to identify miRNAs possibly involved in DC development and function by targeting the transcripts of relevant mouse transcription factors. Examination of DC subsets from the culture of mouse bone marrow with Flt3 ligand identified high expression of miR-124 which was able to target the transcript of TCF4, a transcription factor critical for the development and homeostasis of pDCs. Further expression profiling of mouse DC subsets isolated from in vitro culture as well as via ex vivo purification demonstrated that miR-124 was outstandingly expressed in CD24⁺ cDC1 cells compared to in pDCs and CD172α⁺ cDC2 cells. These results imply that miR-124 is likely involved in the processes of DC subset development by posttranscriptional regulation of a transcription factor(s).

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년 학술대회 논문집 정보 및 제어부문
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• pp.306-308
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• 2006

산업현장에서 가장 많이 활용되고 있는 PID제어기의 이론적인 배경을 토대로 실제 DCS 기반 플랜트에서 PID Tuning Method에 의한 PID제어기를 구현하고 제어성능을 확인한다. 또한 DCS(Distribute Control System)의 PID Controller를 분석하고 전 공정제어 System 중 일부분을 ARMA Modeling하여 만족스런 성능이 구현되도록 최적의 PID gain Parameter를 찾는다.

• 한국컴퓨터정보학회지
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• 제14권2호
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• pp.117-122
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• 2006

이 논문에서는 기존 개발된 일체형의 통합 터미널 보드의 유선방식을 배제하고 무선방식으로 자동제어시스템에서의 중요 신호에 대한 전체적 통합관리시스템 구축을 위한 DCS 터미널 원격 감시 보드를 설계 제작하고 제작된 보드의 동작을 테스트하기 위해 원격감시 프로그램을 구현하여 기능을 평가한다. 구현된 원격감시보드는 전원관리실의 각 릴레이들의 동작상태 및 릴레이와 퓨즈의 이상 유무를 실시간으로 확인이 가능하며 릴레이의 수명을 고려하여 릴레이의 고장을 사전에 예방함으로써 산업분야의 경제적인 효과가 기대된다.

• 대한전자공학회논문지TC
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• 제45권1호
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• pp.97-102
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• 2008

본 논문에서는 휴대폰에서 GSM/DCS/Bluetooth 대역에서 사용되는 내장형 안테나에 관한 것으로 폴딩형태의 루프를 기본 구조로 한다. 폴딩형 루프의 중심에 급전과 단락점을 대칭적으로 형성하여 1/4 파장의 정수배가 되는 주파수에서 공진이 가능하도록 하였다. 이 루프구조의 한쪽 종단에서 개방형 스터브를 구현하였는데 이는 루프구조의 공진기에 개방형 스터브에 의하여 공진 주파수를 낮추는 기능을 갖는다. 또한 개방형 스터브는 PIFA 구조의 기능을 하여 GSM 대역에서 새로운 공진을 추가하여 대역폭의 증대를 가져온다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1995년도 하계학술대회 논문집 B
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• pp.995-998
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• 1995

As the modern industrial processes become more complex, it is getting more difficult to model and control the processes. Naturally, an advanced type of DCS(Distributed Control System) with higher level functions is being sought Advanced DCS is a DCS with advanced functions such as fault diagnosis, GPC(Generalized Predictive Control), NN(Neural Network), and Fuzzy Control. In this thesis, we have studied a fuzzy control algorithm for realizing an advanced DCS. Its algorithm is implemented in a form of function code which is a process control language, being used by the industrial engineers. To verify the realized function code of the fuzzy control, the function code is applied to a continuous casting process of the Pohang Iron & Steel Works in Kwangyang. The rules of the fuzzy control were collected via interviews of the field operators and their operation documents. Finally, usability of the function code of the fuzzy control is shown via simulation for the continuous casting process model.

• 한국시뮬레이션학회:학술대회논문집
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• 한국시뮬레이션학회 2003년도 추계학술대회 및 정기총회
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• pp.159-164
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• 2003

DCS (Distributed Control System) is adapted in the most fossil power plant in our country but that is not true in the nuclear power plant (NPP) because of the safety problem. KEPRI has developed many simulators for the training of the operators working in power plants. With this accumulated high technology we are developing a DCS simulator for the performance verification of the developed DCS for the make-up demin-water treatment system of Kori #3&4. In this paper we explain how we develop the system model and show a simulation result.

• The Journal of Korean Physical Therapy
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• 제30권6호
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• pp.211-217
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• 2018

Purpose: This study is to investigate influence of tDCS on lower limb muscle activity and balance ability in soccer player. Methods: Sessions were conducted with 15 subjects in tDCS group and 15 in action observation training group for 20 minutes, 5 sessions a week, for 8 weeks. All soccer players underwent 30 minutes of plyometric training before main exercise. To evaluate lower limb muscle activation, rectus femoris and biceps femoris were taken measure using surface electromyogram system and to evaluate balance ability, surface area, whole path length, limited of stability were measured using biorescue. Results: Regarding balance shown in surface area, whole path length, limited of stability and muscle activation in rectus femoris and biceps femoris, tDCS group showed more significant change than action bservation training group. Conclusion: Therefore, intervention using tDCS is more effective in improving lower limb muscle activation and balance ability than action observation training.

• BMB Reports
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• 제54권1호
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• pp.31-43
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• 2021

Dendritic cells (DC), which consist of several different subsets, specialize in antigen presentation and are critical for mediating the innate and adaptive immune responses. DC subsets can be classified into conventional, plasmacytoid, and monocyte-derived DC in the tumor microenvironment, and each subset plays a different role. Because of the role of intratumoral DCs in initiating antitumor immune responses with tumor-derived antigen presentation to T cells, DCs have been targeted in the treatment of cancer. By regulating the functionality of DCs, several DC-based immunotherapies have been developed, including administration of tumor-derived antigens and DC vaccines. In addition, DCs participate in the mechanisms of classical cancer therapies, such as radiation therapy and chemotherapy. Thus, regulating DCs is also important in improving current cancer therapies. Here, we will discuss the role of each DC subset in antitumor immune responses, and the current status of DC-related cancer therapies.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.136.2-136.2
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• 2003

Previously, we showed that cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC class I-restricted presentation of exogenous antigen in dendritic cells (DCs). We further characterized the effects of cyclosporin A and tacrolimus on the uptake, processing and cross-presentation of a model antigen, ovalbumin (OVA), in DCs. Treatment of DCs with cyclosporin A or tacrolimus did not inhibit phagocytic activity of DCs. Instead, treatment of DCs with cyclosporin A or tacrolimus inhibited the expression of $H-2K^b$/ molecules complexed with the OVA peptied, SIINFEKL, specifically. (omitted)