• Title/Summary/Keyword: D2C

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C-Flavonoidal Glycosides from Erythrina caffra Flowers

  • El-Masry, Sawsan;Hammoda, Hala M.;Radwan, Mohamed M.;Ross, Samir A.;Zaatout, Hala H.
    • Natural Product Sciences
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    • v.16 no.4
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    • pp.217-222
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    • 2010
  • A phytochemical investigation of the ethanolic extract of Erythrina caffra flowers from an Egyptian origin yielded three C-flavonoidal glycosides; 5,7,4'-trihydroxyflavone-8-C-$\beta$-D-glucopyranoside (vitexin) (1), 5,7,4'-trihydroxyflavone-6-C-$\beta$-D-glucopyranosyl-(1 $\rightarrow$ 2)-$\beta$-D-glucopyranoside (isovitexin-2"-$\beta$-D-glucopyranoside) (2), 5, 7, 4'-trihydroxyflavone-6, 8-di-C-$\beta$-D-glucopyranoside (vicenin-2) (3) and one O-flavonoidal glycoside; kaempferol-3-O-$\beta$-D.glucopyranosyl) (1 $\rightarrow$ 2)-$\beta$-D-glucopyranoside (4). The structures of the isolated compounds (1 - 4) were elucidated using different spectral techniques (UV, 1D and 2D NMR and HRESIMS). This is the first report for the isolation of flavonoidal glycosides from Erythrina caffra. The antibacterial, antifungal, antimalarial, and antileishmanial activities of the isolates were evaluated. In addition, the cytotoxic activity of the ethanolic extract and the main fractions were tested using brine shrimp bioassay.

Gamakamide C and D as Two New Analogues of Bitter-Tasting Cyclic Peptide with Hydantoin Structure from Oyster Crassostrea gigas

  • Jang, Jun Ho;Park, Taesung;Lee, Jong Soo
    • Fisheries and Aquatic Sciences
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    • v.18 no.2
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    • pp.131-135
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    • 2015
  • Two new bitter-tasting cyclic peptides comprising six amino acids, namely gamakamide C and D, were isolated from cultured oysters Crassostrea gigas. Dimethylaminoazobenzene sulfonyl-amino acid analysis detected Val and Leu in gamakamide C and Ile and Leu in gamakamide D. The molecular formula of gamakamide C was determined as $C_{43}H_{60}N_{7}O_8S$ by high-resolution fast atom bombardment mass spectroscopy (HR FAB-MS) ($[M+H]^+m/z822.4200{\Delta}-2.4mmu$), and that of gamakamide D was determined as $C_{43}H_{62}N_7O_8S$ by HR FAB-MS ($[M+H]^+m/z836.4379{\Delta}-2.0mmu$). Comparison of amino acid analyses and fragment ions by MS/MS among gamakamide C, D, and E (known), the structures of gamakamide C and D were confirmed $as-{\small{L}}-Val-{\small{L}}-Met(SO)-{\small{L}}-NMe-Phe-{\small{L}}-Leu-{\small{D}}-Lys-{\small{L}}-Phe-$ and $-{\small{L}}-Ile-{\small{L}}-Met(SO)-{\small{L}}-NMe-Phe-{\small{L}}-Leu-{\small{D}}-Lys-{\small{L}}-Phe-$, respectively.

Characteristics of New Luxury in Louis Vuitton's D2C-Based Mobile Application (D2C(Direct-to-Consumer) 기반 루이비통 모바일 앱에 나타난 뉴 럭셔리(New Luxury) 특성)

  • Kim, Mikyung;Yim, Eunhyuk
    • Journal of the Korean Society of Clothing and Textiles
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    • v.45 no.5
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    • pp.741-757
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    • 2021
  • In addition to direct sales to consumers, the direct-to-consumers (D2C) strategy, which provides specialized experiences and services, communicates closely with a consumer's perspective. This tendency is related to the recent trend wherein the luxury fashion system is being transformed into a new luxury. Therefore, this study analyzes the development of online D2C platforms and investigates the characteristics of new luxury from the functional, symbolic, and experiential dimension perspectives based on mobile apps, which is becoming increasingly important among online D2C platforms. Based on the study results, the premium of new luxury fashion displayed in Louis Vuitton's mobile D2C platform in terms of product utility and functionality is newly defined as a usable luxury experience. Moreover, from the heritage perspective, based on the cultural sympathy of the brand contents, we determine that an attachment can be formed between new luxury fashion consumers and brands. Additionally, the personalization service and experiential content on the D2C platform can directly afford emotional and bonding induced brand immersion in a playful way.

Thermal Behavior and Crystallographic Characteristics of an Epitaxial C49-$TiSi_2$ Phase Formed in the Si (001) Substrate by $N_2$Treatment (Si (001) 기판에서 $N_2$처리에 의해 형성된 에피택셜 C49-$TiSi_2$상의 열적 거동과 결정학적 특성에 관한 연구)

  • Yang, Jun-Mo;Lee, Wan-Gyu;Park, Tae-Soo;Lee, Tae-Kwon;Kim, Joong-Jung;Kim, Weon;Kim, Ho-Joung;Park, Ju-Chul;Lee, Soun-Young
    • Korean Journal of Materials Research
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    • v.11 no.2
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    • pp.88-93
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    • 2001
  • The thermal behavior and the crystallographic characteristics of an epitaxial $C49-TiSi_2$ island formed in a Si (001) substrate by $N_2$, treatment were investigated by X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HRTEM). It was found from the analyzed results that the epitaxial $C49-TiSi_2$ was thermally stable even at high temperature of $1000^{\circ}C$ therefore did not transform into the C54-stable phase and did not deform morphologically. HRTEM results clearly showed that the epitaxial $TiSi_2$ phase and Si have the orientation relationship of (060)[001]$TiSi_2$//(002)[110]Si, and the lattice strain energy at the interface was mostly relaxed by the formation of misfit dislocations. Furthermore, the mechanism on the formation of the epitaxial $_C49-TiSi2$ in Si and stacking faults lying on the (020) plane of the C49 Phase were discussed through the analysis of the HRTEM image and the atomic modeling.

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D609, an Inhibitor of Phosphatidylcholine-specific Phospholipase C, Inhibits Group IV Cytosolic Phospholipase A2

  • Kang, Mi Sun;Jung, Sung Yun;Jung, Kwang Mook;Kim, Seok Kyun;Ahn, Kyong Hoon;Kim, Dae Kyong
    • Molecules and Cells
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    • v.26 no.5
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    • pp.481-485
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    • 2008
  • As an inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC), D609 has been widely used to explain the role of PC-PLC in various signal transduction pathways. This study shows that D609 inhibits group IV cytosolic phospholipase $A_2$ ($cPLA_2$), but neither secretory $PLA_2$ nor a $Ca^{2+}$-dependent $PLA_2$. Dixon plot analysis shows a mixed pattern of noncompetitive and uncompetitive inhibition with $K_i=86.25{\mu}M$ for the $cPLA_2$ purified from bovine spleen. D609 also time- and dose-dependently reduces the release of arachidonic acid from a $Ca^{2+}$- ionophore A23187-stimulated MDCK cells. In the AA release experiment, $IC_{50}$ of D609 was ${\sim375}{\mu}M$, suggesting that this reagent may not enter the cells easily. The present study indicates that the inhibitory effects of D609 on various cellular responses may be partially attributable to the inhibition of $cPLA_2$.

Building up the foundation for the elderly apparel industry through the development on shirt sloper of elderly obese males - Applying CLO 3D program - (노년 비만남성의 셔츠원형 개발을 통한 실버 의류산업 활성화 기반 구축 - CLO 3D 가상착의 시스템 활용 -)

  • Seong, Ok jin;Kim, Sook jin
    • The Research Journal of the Costume Culture
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    • v.28 no.3
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    • pp.299-312
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    • 2020
  • The purpose of this study is to create a shirt sloper suitable for an elderly male body shape by producing virtual models using a 3D-virtualization program, making a torso prototype using the Yuka CAD system, and employing 3D simulation to virtualize and calibrate the model. First, the following three types of obese dummies are implemented through the CLO 3D program: Type 1 exhibits body fat in the lower body; Type 2 exhibits an obese abdomen; and Type 3 displays a balanced form of obesity. Second, for the design of the shirt pattern, the waist back length (measured value+1), back armhole depth (C/10+12+3+0.5~1.5), front armhole depth (back armhole depth 0~1), front interscye (2C/10-1+0.5-0.5), armscye depth (C/10+2+3.5+ 0.5), back interscye (2C/10-1+1), front chest C (C/4+2.5+1), back chest C (C/4+2.5-1), front hem C (C/4+2.5+1(+2)), back hem C (C/4+2.5-1(+2)), cap height (AH/3-5), and biceps width (Front AH-1, Back AH-1) are calculated. Third, the virtual attachment of the shirt pattern is resolved by increasing the front and back armhole depths, and the front and rear wrinkles are improved by adding a back armhole dart. The front hem lift and lateral pull caused by the protrusion of the abdomen are amended by increasing the margin of the chest, waist C, and hip C, with the appearance improved by balanced margin distribution in the front, back, and side panels. The improved retail pattern with an increase in the front armholes C was balanced on the torso plate.

Identification of the Marker-Genes for Dioxin(2, 3, 7, 8- tetradibenzo-p-dioxin)-Induced Immune Dysfunction by Using the High-Density Oligonucleotide Microarray

  • Kim, Jeong-Ah;Lee, Eun-Ju;Chung, In Hye;Kim, Hyung-Lae
    • Genomics & Informatics
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    • v.2 no.2
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    • pp.75-80
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    • 2004
  • In a variety of animal species, the perinatal exposure of experimental animals to the 2,3,7,8-tetrachlorodibenzo­p-dioxin (TCDD) leads to the immune dysfunction, which is more severe and persistent than that caused by adult exposure. We report here the changes of gene expression and the identification of the marker-genes representing the dioxin exposure. The expressions of the transcripts were analyzed using the 11 K oligonucleotide­microarray from the bone marrow cells of male C57BL/6J mice after an intraperitoneal injection of $1{\mu}g$ TCDD/kg body weight at various time intervals: gestational 6.5 day(G6.5), 13.5 day(G13.5), 18.5 day(G18.5), and postnatal 3 (P3W)and 6 week (P6W). The type of self-organizing maps(SOM) representing the specific exposure dioxin could be identified as follows; G6.5D(C14), G13.5D(C0, C5, C10, C18), G18.5D(7): P3W(C2, C21), and P6W(C4, C15, C20). The candidate marker-genes were restricted to the transcripts, which could be consistently expressed greater than $\pm$2-fold in three experiments. The resulting candidates were 85 genes, the characteristics of that were involved in cell physiology and cell functions such as cell proliferation and immune function. We identified the biomarker-genes for dioxin exposure: smc -like 2 from SOM C14 for the dioxin exposure at G6.5D, focal adhesion kinase and 6 other genes from C0, and protein tyrosine phosphatase 4a2 and 3 other genes from C5 for G13.5D, platelet factor 4 from C7 for G18.5D, fos from C2 for P3W.

Oxygen Consumption of Far Eastern Catfish, Silurus asotus, on the Different Water Temperatures and Photoperiods (참메기, Silurus asotus의 수온과 광주기 변화에 따른 산소 소비량)

  • JO Jae-Yoon;KIM Youhee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.1
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    • pp.56-61
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    • 1999
  • Oxygen consumption rate of Far eastern catfish, Silurus asotus, weighing 280g, was measured using continuous flow respirometry chamber linked computer monitoring system. Mean oxygen consumption rates at $15^{\circ}C,\;20^{\circ}C,\;25^{\circ}C$, and $30^{\circ}C$ were ranged in 35.2$\~96.4mg\;O_2/kg$ fish/hr, 78.6$\~127.9mg\;O_2/kg$ fish/hr, 120.1$\~231.7mg\;O_2/kg$ fish/hr, and 197.5$\~352.3mg\;O_2/kg$ fish/hr, respectively. The oxygen consumption rates increased with increasing water temperature (p<0.05). A photoperiod-mediated oxygen consumption rates was higher during the light period than during the darkness (P<0.05). When acclimated with different photoperiods, 24L:0D, 12L:12D, and 0L:24D, the lowest oxygen consumption rate was observed in the continuous darkness (0L:24D). The differences between maximum and minimum oxygen consumption rates oyer 24 hour increased with increasing water temperature and the difference was the highest in 12L:12D. Oxygen consumption rate changed suddenly at dawn and at dusk.

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Physiological Study on the Hybrid by Interspecific Crossing between Porphyra pseudolinearis and P. dentata (Bangiales, Rhodophyta), Two Dioecious Species in Culture (잇바디돌김(Porphyra dentata Kjellman)과 긴잎돌김(Porphyra pseudolinearis Ueda)의 종간 교잡종의 생리특성)

  • 김남길
    • Journal of Aquaculture
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    • v.13 no.4
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    • pp.353-357
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    • 2000
  • Porphyra pseudolinearis and P. dentata from Korea were crossed and the hybrid was cultured at different temperatures (5, 10, 15, 20 or $25^{\circ}C$), photon flux densities (10, 20, 40 or 80${\mu}$mol m$^{-2}$s$^{-1}$) under photoperiods (14L:10D and 10L:14D). In the hybrids, the conchocelis grew faster at 2$0^{\circ}C$ and 40$\mu$mol m$^{-2}$ s$^{-1}$ at $25^{\circ}C$ only, and were abundant, when cultured under 10L:14D. Foliose thalli of the hybrid grew rapidly at conditions of 10-2$0^{\circ}C$, 10L:14D and 15-2$0^{\circ}C$, 14L:10D but slowly at 5 and 2$0^{\circ}C$. No archeospores were observed any tested culture condition. Spermatangial and zygotosporangial sori were formed at the marginal portion o mature thallus. Zygotospores from the hybrid were released at 10-2$0^{\circ}C$ under both photoperiods, and gave rise to form conchocelis filament. Monoecious thalli were observed at 1$0^{\circ}C$ under 14L:10D. Neither monospores nor protothalli were produced from the conchocelis in culture.

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APPLICATIONS OF THE SCHWARZ LEMMA RELATED TO BOUNDARY POINTS

  • Bulent Nafi Ornek
    • The Pure and Applied Mathematics
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    • v.30 no.3
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    • pp.337-345
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    • 2023
  • Different versions of the boundary Schwarz lemma for the 𝒩 (𝜌) class are discussed in this study. Also, for the function g(z) = z+b2z2+b3z3+... defined in the unit disc D such that g ∈ 𝒩 (𝜌), we estimate a modulus of the angular derivative of g(z) function at the boundary point 1 ∈ 𝜕D with g'(1) = 1 + 𝜎 (1 - 𝜌), where ${\rho}={\frac{1}{n}}{\sum\limits_{i=1}^{n}}g(c_i)={\frac{g^{\prime}(c_1)+g^{\prime}(c_2)+{\ldots}+g^{\prime}(c_n)}{n}}{\in}g^{\prime}(D)$ and 𝜌≠1, 𝜎 > 1 and c1, c2, ..., cn ∈ 𝜕D. That is, we shall give an estimate below |g"(1)| according to the first nonzero Taylor coefficient of about two zeros, namely z = 0 and z ≠ 0. Estimating is made by using the arithmetic average of n different derivatives g'(c1), g'(c2), ..., g'(cn).