• Title/Summary/Keyword: D&I can

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The Relationship between Taq I A Dopamine $D_2$ Receptor Polymorphism and Therapeutic Response to Antipsychotics in Schizophrenic Patients (정신분열병환자에서 Taq I A 도파민 $D_2$ 수용체 다형성과 항정신병약물의 치료반응과의 연관)

  • Kang, Cheol Joong
    • Korean Journal of Biological Psychiatry
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    • v.12 no.2
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    • pp.107-113
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    • 2005
  • Purpose:In an attempt to predict the interpersonal differences of therapeutic response to antipsychotic drugs on pharmaco-genetic bases, this study was designed to investigate the relationship between the therapeutic response to antipsychotic drugs and Taq I A dopamine $D_2$ receptor polymorphism in schizophrenic patients. Methods:The subjects were 158 patients diagnosed with schizophrenia(DSM-IV). The therapeutic response to antipsychotic drugs was evaluated using the Treatment Response Scale(TRS) retrospectively. Patients were divided into two groups, dopamine receptor antagonist responders, and serotonin-dopamine antagonist responders. The patients' Taq I A dopamine $D_2$ receptor polymorphism was determined by polymerase chain reaction(PCR) and restriction fragment length polymorphism(RFLP). Results:The dopamine receptor antagonist responders had the A1 allele in significantly higher incidences (${\chi}^2$(1)=4.875, p=0.027, two-tailed). No significant difference was found among the serotonin-dopamine antagonist responders between those with or without the A1 allele. Conclusions:The patients with the A1 allele responded better to dopamine receptor antagonists than those with no A1 allele. Based on these results, it is suggested that the pharmacological effect of dopamine receptor antagonists can be predicted depending on the presence of the A1 allele in schizophrenic patients.

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Performance Analysis for Selection Decode-and-Forward Relay Networks with Differential Modulation over Rayleigh Fading Channels (레일리 페이딩 채널에서 차등 변조기법을 이용한 선택적 복호 후 재전송 중계 네트워크의 성능 분석)

  • Kong, Hyung-Yun;Bao, Vo Nguyen Quoc
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.35 no.1A
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    • pp.1-9
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    • 2010
  • This paper offers performance analysis of selection decode and forward (DF) networks with differential modulation/demodulation for an arbitrary number of relays in independent but not identically distributed Rayleigh fading channels. We have shown that the selection DF protocol with differential modulation can achieve full diversity in both independent identically distributed (i.i.d.) and independent but not identically distributed (i.n.d.) Rayleigh fading channels, and the performance loss due to using non-coherent detection is not substantial. Furthermore, we study the impact of combining techniques on the performance of the system by comparing a system that uses selection combining (SC) to one that uses maximum ratio combining (MRC). Simulations are performed and show that they match exactly with analytic ones in high SNR regime.

Development of the wooden window design implementing D.I.Y. modular system (D.I.Y. Modular 방식을 도입한 목재 창 디자인 개발)

  • Kim, Jin-Young;Kim, Do-Yeon;Roh, Yang-Mi;Park, Hyo-Mi
    • Archives of design research
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    • v.17 no.4
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    • pp.401-404
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    • 2004
  • The proposal defines a Do It Yourself system that radically changes the traditional concept of window. it is based on a D.I.Y. system that allows the users to fully customize its windows according to his needs, combining a wood frame with different elements. At the same time, it is preserving the basic function of light and ventilation and defining a new aesthetic code. Despite the restriction of size and shape, the user can choose among many different elements to increase the space efficiency he needs and to give a more enjoyable perspective to the window both in and out door. Also, All the elements are standard and they can be mass-produced according to specific market needs. Therefore, the window of the future will not be just a thin membrane in between the inside and the outside, but it will also play an important "identification role. According to each individual pick, these new windows will help to give identify to anonymous metropolitan areas and to the people living within them.

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Printing of Polyester and Cotton Blends using Diaminoanthraquinone Disperse Dye and Monochlorotriazinyl Reactive Dye Mixtures (디아미노안트라퀴논계 분산염료/모노클로로트리진형 반응염료에 의한 폴리에스테르/면 혼방 직물의 날염)

  • 강숙녀
    • Textile Coloration and Finishing
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    • v.6 no.2
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    • pp.30-39
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    • 1994
  • To study the printing behaviors of Polyester and cotton(P/C) fabrics printed with disperse and reactive dyes, the effects of alkalis on the fixation of reactive dyes and the alkali-stability of disperse dyes in various methods of fixation were examined. The anthraquinone disperse dyes which have diamino derivatives as substituents without hydroxy group, such as C.I. Disperse Violet 1(D.V.1), C.I. Disperse Violet 28(D.V.28) and C.I.Disperse Blue 60(D.B.60) showed good results of fixation without regard to the concentration of NaHCO$_3$. In case of high temperature steaming(HTS) and unsaturated steaming(US)/HTS, D.V. 1 was alkali-stable and effective for P/C printing. A good result was obtained with D.V.1 and C.I.Reactive Orange 13(R.O.13) paste of 4% $K_{2}CO_{3}$. It was found that the unfixed D.V.28 bearing chloro group can hinder the fixation of monochlorotriaxinyl reactive dyes, and D.B.60 made little stain on 100% cotton. In thermosol(Tm), the dye uptake of D.V.1 was not decreased so much, but those of D.V.28 and D.B.60 were greatly decreased.

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Development of Data Automation Algorithm for GIS Service in Universal 3D Graphics Engine (범용 3D 그래픽 엔진의 GIS 정보 서비스를 위한 데이터 자동변환 알고리즘 개발)

  • Kim, Hyeong Hun;Park, Hyeon Cheol;Choi, Hyeoung Wook;Gang, Su Myung;Choung, Yun Jae
    • Journal of Korea Multimedia Society
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    • v.20 no.3
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    • pp.581-592
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    • 2017
  • Geographic Information System (GIS) is a method of expressing objects in a space. Currently, many research and developments are being conducted to implement 3D GIS. In previous studies, 3D GIS applications have been developed using Unity 3D, which is a 3D engine with good development accessibility. However, it requires manual work to enter various formats of GIS data, making it difficult to immediately reflect GIS data that change frequently. To improve this problem, this study developed a method for automatically reading and outputting various GIS data from the existing Unity 3D application. The improved application could read Satellite Images, Aerial Photographs, Digital Elevation Models (DEM) and Shapefiles with no transformation through other commercial programs, and they could be implemented as 3D objects. This study automated the GIS data conversion which had been manually performed and as a result, the manpower, time, and resources required for 3D GIS implementation can be saved.

A study on specification development of defense R&D CALS system (국방 연구개발 CALS체계 구축을 위한 체계 요구사항 연구)

  • 김철환;진상철
    • Proceedings of the CALSEC Conference
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    • 1999.11a
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    • pp.85-92
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    • 1999
  • The current R&B system has a lot of problems caused by complexity of the system and lack of IDE concept among the related offices and organizations. IDE concept is building Integrated database with data which applied standards and digitalized. So R&D CALS system should be established for the related offices and organizations can use data which created during R&D life-cycle in IDE. In this paper, I suggested system requirements and system quality factors for building IDE based upon SSS form.

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Identification of nonlinear distortion for a high-density magnetic recording channel using an I.I.D. signal (I.I.D. 신호를 이용한 고밀도 자기 기록 채널의 비선형 왜곡 추정)

  • 전원기;조용수
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.33B no.3
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    • pp.133-141
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    • 1996
  • As the recording density of digital magnetic recording channels increased, the nonlinear distortion caused by inadequate rise-times, demagnetizing field, and overwrite effect during the recording process becomes significant, resulting in limitation on the recording rate. In this paper, a new method for identifying the nonlinear distortion in hihg-density magnetic recording channel using and i.i.d. (independent, identically distributed) inut is described. The proposed method does not require the operatin of large-size matrix inversion which are necessary for the conventional method, and it enables us to estimate nonlinear parameters transition shifts, which can be used to compensate the nonlinear distortion, is demonstrated by computer simulations.

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A Study on the Development of iGPS 3D Probe for RDS for the Precision Measurement of TCP (RDS(Robotic Drilling System)용 TCP 정밀계측을 위한 iGPS 3D Probe 개발에 관한 연구)

  • Kim, Tae-Hwa;Moon, Sung-Ho;Kang, Seong-Ho;Kwon, Soon-Jae
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.11 no.6
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    • pp.130-138
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    • 2012
  • There are increasing demands from the industry for intelligent robot-calibration solutions, which can be tightly integrated to the manufacturing process. A proposed solution can simplify conventional robot-calibration and teaching methods without tedious procedures and lengthy training time. iGPS(Indoor GPS) system is a laser based real-time dynamic tracking/measurement system. The key element is acquiring and reporting three-dimensional(3D) information, which can be accomplished as an integrated system or as manual contact based measurements by a user. A 3D probe is introduced as the user holds the probe in his hand and moves the probe tip over the object. The X, Y, and Z coordinates of the probe tip are measured in real-time with high accuracy. In this paper, a new approach of robot-calibration and teaching system is introduced by implementing a 3D measurement system for measuring and tracking an object with motions in up to six degrees of freedom. The general concept and kinematics of the metrology system as well as the derivations of an error budget for the general device are described. Several experimental results of geometry and its related error identification for an easy compensation / teaching method on an industrial robot will also be included.

Standardization of diagnosis of cold hypersensitivity of hands and feet by D.I.T.I.

  • Lee, Kyung-Sub
    • Journal of Oriental Medical Thermology
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    • v.3 no.1
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    • pp.15-19
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    • 2004
  • Cold hypersensitivity means a condition feeling cold at a temperature when one should not feel so. Cold hypersensitivity has been diagnosed based on the patient's subjective complaints. But these days, cold hypersensitivity can be diagnosed by the help of D.I.T.I.(Digital Infrared Thermal Imaging) This study is designed to verify the validity of diagnosis of cold hypersensitivity by D.I.T.I. Thermographic findings of 100 outpatients who visited the Kangnam Korean Hospital, KyungHee University, Seoul, Korea, from June 2000 to November 2000 were analyzed. The experimental group consisted of 50 patients who complained cold hypersensitivity, and for the control group, 50 patients who did not complain cold hypersensitivity. For the diagnosis of cold hypersensitivity of the hands, thermographic measurements were performed on two pairs of areas(palm-upper arm and back of hand-upper arm). And for that of the feet, other two pairs of areas(anterior thigh-top of the feet and posterior thigh-heel). When the criterion for thermal deviation between the palm and the upper arm was appointed as higher than $0.3^{\circ}C$, the sensitivity was 94.0% and the specificity, 90.0%. And when the criterion for that between the anterior thigh and the top of feet was appointed higher than $2.0^{\circ}C$, the sensitivity was 94.0% and the specificity, 76.0%. Through this study, the diagnostic standard for cold hypersensitivity of hands and feet could be presented.

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Empirical Analysis of DEA models Validity for R&D Project Performance Evaluation : Focusing on Rank Correlation with Normalization Index (R&D 프로젝트 성과평가를 위한 DEA모형의 타당성 실증분석 : 정규화지표와의 순위상관을 중심으로)

  • Park, Sung-Min
    • IE interfaces
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    • v.24 no.4
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    • pp.314-322
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    • 2011
  • This study analyzes a relationship between Data Envelopment Analysis(DEA) efficiency scores and a normalization index in order to examine the validity of DEA models. A normalization index concerned in this study is 'sales per R&D project fund' which is regarded as a crucial R&D project performance evaluation index in practice. For this correlation analysis, three distinct DEA models are selected such as DEA basic model, DEA/AR-I revised model(i.e. DEA basic model with Acceptance Region Type I constraints) and Super-Efficiency(SE) model. Especially, SE model is adopted where efficient R&D projects(i.e. Decision Making Units, DMU's) with DEA efficiency score of unity from DEA basic model can be further differentiated in ranks. Considering the non-normality and outliers, two rank correlation coefficients such as Spearman's ${\rho}_s$ and Kendall's ${\tau}_B$ are investigated in addition to Pearson's ${\gamma}$. With an up-to-date empirical massive dataset of n = 482 R&D projects associated with R&D Loan Program of Korea Information Communication Promotion Fund in the year of 2011, statistically significant (+) correlations are verified between the normalization index and every model's DEA efficiency scores with all three correlation coefficients. Especially, the congruence verified in this empirical analysis can be a useful reference for enhancing the practitioner's acceptability onto DEA efficiency scores as a real-world R&D project performance evaluation index.