• Journal of Technology Innovation
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• v.25 no.4
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• pp.145-164
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• 2017

This research targeted discussions on re-utilization of Korean creative economic innovation center. It is meaningless to simply discuss its re-organization. The focus of this study was to find a way that transforms it into totally new one. The study followed several steps. First, it delineated criteria from existing literature for comparing creative eco-system of Silicon valley, Kyoto eco-system and eco-system based on Korean creative economic innovation center. Second, it compared the three eco-systems in details. Third, it discussed a direction for transforming eco-system based on Korean creative economic innovation center. It was suggested that the Kyoto eco-system can be a role model. It was also suggested that governmental role should be changed from controller to facilitatior which stimulates regulation relaxations and helps to establish market formation.

• Microbiology and Biotechnology Letters
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• v.51 no.1
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• pp.37-42
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• 2023

Neutral and non-essential amino acid, glutamine (Gln), plays an essential role in supplying nitrogen to all the amino acids and nucleotides in the mammalian body. Gln is also the most important carbon source that provides intermediates for gluconeogenesis and fatty acid synthesis and supplements the tricarboxylic acid cycle in fast-growing cancer cells. Among the known 14 Gln transporter genes, soluted carrier family 1 member 5 (SLC1A5) has been reported to be closely associated with cancer cell growth. Three variants (v1, v2, and v3) have been derived from SLC1A5. Here, we established a heterologous gene expression system for the active form of human SLC1A5 variant-2 (hSLC1A5v2) in Escherichia coli. v2 is the smallest variant that has not yet been studied. Four expression systems were investigated: pBAD, pCold, pET, and pQE. We also addressed the problem of codon usage bias. Although pCold and pET overexpressed hSLC1A5v2 in E. coli, they were functionally inactive. hSLC1A5v2 using the pBAD system was able to catalyze the successful transport of Gln, even if it was not highly expressed. Initial activity of hSLC1A5v2 for [¹⁴C] Gln uptake in E. coli reached up to 6.73 μmole·min^-1·gDW^-1 when the cell was induced with 80 mM L-arabinose. In this study, we demonstrated a heterologous expression system for the human membrane protein, SLC1A5, in E. coli. Our results can be used for the functional comparison of SLC1A5 variants (v1, v2, and v3) in future studies, to facilitae the developement of SLC1A5 inhibitors as effective anticancer drugs.

• Korean Institute of Interior Design Journal
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• v.22 no.2
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• pp.120-130
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• 2013

Since Seoul city supplied 'Sangsang Children's Playground', domestic playgrounds are changing from formal facilities to creative play and learning space recently. From eco-friendly safe playground model development project, eco-friendly playground planning and its actual cases have been occasionally introduced. However, we could not know how well most playgrounds reflect eco-friendly features and whether they are eco-friendly or not because the definition about the concept of eco-friendly playground is inadequate and there are not the specific planning guidelines and evaluation standards for making the eco-friendly playground. Therefore, the development of guidelines for the construction of eco-friendly playground is required and evaluation guidelines for them should be made for the active dissemination of the actual eco-friendly playground and the proper construction of the eco-friendly playground. In this study, we defined the concept of eco-friendly outdoor playground and presented the types and characteristics of the playground based on the concept and suggested basic plan guidelines based on the existing requirements for becoming eco-friendly playground. For this purpose, we checked the plan's common points in the existing playground configuration requirements, installation standards, regulations, and safety standards, and offered the planning elements and guidelines through the analysis of outdoor space evaluation standard in eco-friendly safe playground guidelines and eco-friendly building certification system.

• Korean Institute of Interior Design Journal
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• v.20 no.6
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• pp.19-26
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• 2011

The purpose of this study was to small house plans according to the preferred type of emotional design. The human emotions was a major factor for small houses plan's needs. In this study is direction of the basic plan for the small houses of the spatial planning and services and the needs of community facilities. Preferred types of emotional design was identify the propensity of consume, adjectives, colors and forms. For this study, survey methods were used for data collection. The effective numbers of survey questionnaire was 183, and the survey analysis has been made by using of SPSS win 18.0. The major findings were as followings: 1) Preferred types of emotional design were "Eco-Classic oriented group", "Unspecified commonness group", "Creative design oriented group" classified. 2) "Eco-Classic oriented group" wanted Eco-system and the community space. "Unspecified commonness group" wanted Simple and universal style. "Creative design oriented group" wanted flexible styles and various items. Therefore, depending on need group is the main target-specific as well as flat planning and interior style facilities and the provision of services to be competitive in the small house could indicate. These results can provide improvement guidelines for the small house plans.

• Proceedings of the KSR Conference
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• 2004.10a
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• pp.1757-1764
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• 2004

It is the urgent task of induce the inhabitants to utilize the public transportation instead of the personal transportation to dissolve the traffic jam. But construction of the subway, the representative substitute means, demands a great of investment expense including various kinds of expenses. So the technical development and research of standardization of FRT(Fuel cell Rubber tired Train), the eco-friendly public transportation system low in construction expenses, effective, excellent in approach as well as in traffic, are propelled positively. This project wants to propose exterior design FRT in which original creative methods are utilized with the target of development and construction of FRT which coincide with anthropocentric eco-friendly traffic system. Utilizing the proposed style as the basic materials, this project wants to grasp difficulties, and to establish the way to solve and develop them.

• Proceedings of the Korea Information Processing Society Conference
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• 2018.10a
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• pp.339-342
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• 2018

The resent work is about the design and installation of the 60 URT heat pump according to the need. This design is eco-friendly, easily available, reduces maintenance and electricity cost. The dimensions of heat pump is $1500mm{\times}500mm{\times}1940mm$ (i.e length 1500 mm, width 500 mm and height 1940 mm) is installed on site. It can be operated with automation (PID) and controlled by sensors. The performance of and heat pump is evaluated experimentally by the monitoring system.

• Fashion & Textile Research Journal
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• v.19 no.3
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• pp.259-266
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• 2017

In a contemporary fashion along with the advance of high technology, development of a new material is being increasingly emphasized and the need of creative convergence using a computer is being expanded. As a global designer who appeared through association between Japan and the West, Issey Miyake has been continually pursuing a new challenge and a solution using high technology, leading the globalization of Japanese fashion. This research aims at examining design characteristics of Issey Miyake collection's A-POC showing a new paradigm, that is, an innovative clothing manufacture system to input information on materials, colors and shapes into a textile machine based on the computer program and manufacture a cylindrical fabric for completion of seamless clothing without sewing or cutting. A-POC is evolving continually through the development of new materials including recycled fibers and organics together with diversification of processing technology. Besides, it shows design characteristics including an integrated manufacturing method, autonomy for customers' selection, practicality for comfortable wearing by the majority, environment friendly idea to reduce waste of fabrics and materials and a new presentation through convergence of exhibition concepts of modern art. This research on Issey Miyake's A-POC characteristics is expected to present a role of fashion designers in a new design idea and paradigm of contemporary clothing using high technology.

• Journal of Distribution Science
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• v.14 no.9
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• pp.31-45
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• 2016

Purpose - This study develops a simulation model that looks at the dynamics between social capital and business performance in strategic networks to understand their behaviors in relation to each other, and to suggest dynamic relationship strategies. Research design, data, and methodology - Based on existing literature, this study identifies the complex causal loop diagram on social capital and business performance in strategic networks, and converts them into a simulation model for observing how the changes in business environment and relationship dependency affect social capital and business performance. Results - The simulation results showed that, first, the formation in social capital and business performance of networks with low relationship dependency was less affected by the changes in business environment. Second, the formation in social capital and business performance of networks with high relationship dependency was negatively impacted by the changes in business environment. In other words, higher relationship dependency strengthened the impact of changes in business environment on business performance. Conclusions - Thus, this study confirmed that in strategic networks, the changes in business environment and the degree of relationship dependency dynamically affect business performance, and that relationship dependency mediates the degree in which changes in the business environment affect business performance. The results of the simulations were further verified through actual business cases.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.5
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• pp.963-971
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• 2016

This paper is a research of gaze analysis for measuring task switching behavior at multiple windows in GUI of windowing system. Previous methods that define area of interest for categorizing gaze had difficulties to define dynamic content that disappears or changes over time. On the other hand, this study suggests a new method to categorize gaze that defines Area of interest in a unit of window during the eye tracking experiment. In this paper, we constructed the conception of WOI(Window of Interest) in GUI of windowing system. Therefore, we developed a system using an eye tracker device and implemented a number of experiments. In addition, we analyzed the number of task switching and proportion of watched content. The method in the study comprehend from previous researches as it can measure and analyze the multi-tasking behaviors using multiple numbers of windows.

• Korean System Dynamics Review
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• v.15 no.4
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• pp.5-28
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• 2014

Derivatives can be easily bought by those companies that need to hedge foreign currency debt or foreign currency assets through the financial market, considering their exchange rate exposure from international trade. The derivatives market has been growing rapidly due to the needs for investment and hedging. To manage foreign exchange risk, companies hedge risks through financial derivatives. According to our study, hedging is an effective way to mitigate the impact of exposure to exchange risk, as long as companies are only hedging underlying assets. Yet, covetous attitude toward the profit from derivatives and unexpected changes in exchange rate can cause problems for companies. This study analyzed the structural risks of derivatives with analysis of system dynamics. In particular, many companies suffered substantial loss due to KIKO during the economic crisis. We explained the problem therein through dynamic analysis. In addition, we revealed the structural problem that could cause a sudden spike in losses through simulations.