• Biomolecules & Therapeutics
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• v.29 no.1
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• pp.22-30
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• 2021

Till the 21st century, fatty acids were considered as merely building blocks for triglycerides, phospholipids, or cholesteryl esters. However, the discovery of G protein-coupled receptors (GPCRs) for free fatty acids at the beginning of the 21st century challenged that idea and paved way for a new field of research, merged into the field of receptor pharmacology for intercellular lipid mediators. Among the GPCRs for free fatty acids, free fatty acid receptor 4 (FFA4, also known as GPR120) recognizes long-chain polyunsaturated fatty acids such as DHA and EPA. It is significant in drug discovery because it regulates obesity-induced metaflammation and GLP-1 secretion. Our study reviews information on newly developed FFA4 agonists and their application in pathophysiologic studies and drug discovery. It also offers a potency comparison of the FFA4 agonists in an AP-TGF-α shedding assay.

• Journal of Korean Society on Water Environment
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• v.27 no.4
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• pp.413-424
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• 2011

The study was aimed to evaluate the applicability of a three-dimensional (3D) hydrodynamic and water quality model, ELCOM-CAEDYM for Yongdam Reservoir, Korea. The model was applied for the simulations of hydrodynamics, thermal stratification processes, stream density flow propagation, and water quality parameters including dissolved oxygen, nutrients, organic materials, and algal biomass (chl-a) for the period of June to December, 2006. The field data observed at four monitoring stations (ST1~ST4) within the reservoir were used to validate the models performance. The model showed reasonable performance nevertheless low frequency boundary forcing data were provided, and well replicated the physical, chemical, and biological processes of the system. Simulated spatial and temporal variations of water temperature, nutrients, and chl-a concentrations were moderately consistent with the field observations. In particular, the model rationally reproduced the succession of different algal species; i.e., diatom dominant during spring and early summer, after then cyanobacteria dominant under warm and stratified conditions. ELCOM-CAEDYM is recommendable as a suitable coupled 3D hydrodynamic and water quality model that can be effectively used for the advanced water quality management of large stratified reservoirs in Korea.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.27 no.9
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• pp.775-782
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• 2016

In this paper, we propose a dual-band GPS antenna using a single-layer coupled-feed structure for improvement of isolation and design complexity. The proposed antenna consists of a central feed patch and outer dual loops, and the loops are electromagnetically fed by the feed patch to induce currents. This feeding network can improve the isolation between antenna elements arranged in small arrays because the magnetic field strength near the antenna is minimized by confining the fields around the dual loops. The isolation characteristics of the proposed antenna are compared with those of the conventional multi-layer patch antenna, and the average field strength and the isolation are improved by 3 dB and 2 dB, respectively, which verifies that the antenna is suitable for small CRPA arrays.

• Korean Journal of Materials Research
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• v.12 no.9
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• pp.724-728
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• 2002

Inductively-coupled $N_2$O plasma was utilized to grow silicon dioxide at low temperature and applied to fabricate polycrystalline-silicon thin film transistors. At $400^{\circ}C$, the thickness of oxide was limited to 5nm and the oxide contained Si≡N and ≡Si-N-Si≡ bonds. The nitrogen incorporation improved breakdown field to 10MV/cm and reduced the interface charge density to $1.52$\times$10^{11}$ $cm^2$ with negative charge. The $N_2$O plasma gate oxide enhanced the field effect mobility of polycrystalline thin film transistor, compared to $O_2$ plasma gate oxide, due to the reduced interface charge at the $Si/SiO_2$ interface and also due to the reduced trap density at Si grain boundaries by nitrogen passivation.

• Journal of Soil and Groundwater Environment
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• v.22 no.6
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• pp.22-28
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• 2017

The accuracy of analytical results in response to the use of different additives ($NH_4Cl$, KCl, $LaCl_3$) and oxidant gases was evaluated and compared by using Atomic Absorption Spectrometry (AAS). Identification of spectroscopic interferences and possible improvements in Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES) analysis were also discussed. The average accuracies of total chromium using Certified Reference Materials (CRMs) were found to be 72.1~94.2% in air/acetylene flame condition by AAS, and they were improved to 100.5~110.5% when the oxidants was changed to nitrous oxide rather than adding the additives. The field samples showed similar trends to CRMs, but chromium concentrations were highly variable depending on analytical conditions. The average accuracies using CRMs were estimated to be 89.3~166.1% by ICP-AES, and improved to below 121.7% after eliminating iron interference. Field samples with low chromium and high iron concentration were measured to be > 30% lower in total chromium concentrations by ICP-AES than AAS in nitrous oxide/acetylene flame. Total chromium concentrations in soil could be analyzed with better accuracy under nitrous oxide/acetylene flame by AAS because it was more effective to increase the temperature of the flame than to eliminate the chemical interference for maximizing atomization of chromium. When using ICP-AES, interference substances, total chromium levels, and analytical conditions should be also considered.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.8
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• pp.853-862
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• 2012

The present study develops a method for directly measuring the temperature field in the primary deformation zone with a high spatial resolution during 2-D orthogonal machining. This is enabled by the use of a high-speed, charge-coupled device (CCD) based, infra-red (IR) imaging system which allows characteristics of the temperature field such as the location and magnitude of the highest temperature and temperature gradient in the primary deformation zone to be identified. Based on these data, the relation between the machining temperature and the cutting conditions is investigated.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2001.09a
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• pp.83-90
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• 2001

The site effects of local geological conditions on seismic ground motion are performed using 2D numerical method. For the analysis, a numerical method far ground response analysis using FE-BE coupling method is developed. The total system is divided into two parts so called far field and near field. The far field is modeled by boundary element formulation using the multi-layered dynamic fundamental solution that satisfied radiational condition of wave. And this is coupled with near field modeled by finite elements. In order to verify the seismic response analysis, the results are compared with those of commercial code. As a result, it is shown that the developed method can be an efficient numerical method to solve the seismic response analysis of the site effect in 2D problem.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2002.09a
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• pp.106-113
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• 2002

In this study, a numerical analysis method for soil-pile interaction in frequency domain problem is presented. The total soil-pile interaction system is divided into two parts so called near field and far field. In the near field, beam elements are used for a pile and plain strain finite elements for soil. In the far field, dynamic fundamental solution for multi-layered half planes based on boundary element formulation is adopted for soil. These two fields are coupled using FE-BE coupling technique In order to verify the proposed soil-pile interaction analysis, the dynamic responses of pile on multi-layered half planes are simulated and the results are compared with the experimental results. Also, the dynamic response analyses of interface spring elements are performed. As a result, less spring stiffness makes the natural frequency decrease and the resonant amplitude increase.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.10a
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• pp.463-466
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• 2002

The Field Robot means the machinery applied for outdoor tasks in construction, agriculture and undersea etc. In this paper, to field-robotize a hydraulic excavator, we have proposed a robust and systematic controller design method. Disturbance observer is used as inner controller to reshape the excavating system into the linear dynamics of nominal model by compensating coupled nonlinear terms, model uncertainties and external load variations. Using the linear model that is obtained through off-line system identification, a H control scheme is applied to construct a disturbance observer and a servo-controller systematically.

• Journal of the Semiconductor & Display Technology
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• v.11 no.1
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• pp.61-65
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• 2012

In this study, for use of carbon nanotubes (CNTs) as a cold cathode of x-ray tubes, we examine the effects of selective growth of CNTs on their field emission properties and long-term stability. The selective growth of CNTs was performed by selectively etching the catalyst layer which was used for CNTs' nucleation. CNTs were grown on conical-type tungsten substrates using an inductively-coupled plasma chemical vapor deposition system. For all the grown CNTs, their morphologies and microstructures were analyzed by field-emission scanning electron microscope and Raman spectroscopy. The electron-emission properties of CNTs and the long-term stability of emission currents were measured and characterized according to the CNTs' growth position on the substrate.