• Title/Summary/Keyword: Cortex-A8

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Altered Functional Disconnectivity in Internet Addicts with Resting-State Functional Magnetic Resonance Imaging

  • Seok, Ji-Woo;Sohn, Jin-Hun
    • Journal of the Ergonomics Society of Korea
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    • v.33 no.5
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    • pp.377-386
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    • 2014
  • Objective: In this study, we used resting-state fMRI data to map differences in functional connectivity between a comprehensive set of 8 distinct cortical and subcortical brain regions in healthy controls and Internet addicts. We also investigated the relationship between resting state connectivity strength and the level of psychopathology (ex. score of internet addiction scale and score of Barratt impulsiveness scale). Background: There is a lot of evidence of relationship between Internet addiction and impaired inhibitory control. Clinical evidence suggests that Internet addicts have a high level of impulsivity as measured by behavioral task of response inhibition and a self report questionnaire. Method: 15 Internet addicts and 15 demographically similar non-addicts participated in the current resting-state fMRI experiment. For the connectivity analysis, regions of interests (ROIs) were defined based on the previous studies of addictions. Functional connectivity assessment for each subject was obtained by correlating time-series across the ROIs, resulting in $8{\times}8$ matrixs for each subject. Within-group, functional connectivity patterns were observed by entering the z maps of the ROIs of each subject into second-level one sample t test. Two sample t test was also performed to examine between group differences. Results: Between group, the analysis revealed that the connectivity in between the orbito frontal cortex and inferior parietal cortex, between orbito frontal cortex and putamen, between the orbito frontal cortex and anterior cingulate cortex, between the insula and anterior cingulate cortex, and between amydgala and insula was significantly stronger in control group than in the Internet addicts, while the connectivity in between the orbito frontal cortex and insula showed stronger negative correlation in the Internet addicts relative to control group (p < 0.001, uncorrected). No significant relationship between functional connectivity strength and current degree of Internet addiction and degree of impulsitivy was seen. Conclusion: This study found that Internet addicts had declined connectivity strength in the orbitofrontal cortex (OFC) and other regions (e.g., ACC, IPC, and insula) during resting-state. It may reflect deficits in the OFC function to process information from different area in the corticostriatal reward network. Application: The results might help to develop theoretical modeling of Internet addiction for Internet addiction discrimination.

A Comparison of Phenolic Components in Cinnamon Medicines

  • Kim, Chae Won;Ko, Jun Hwi;Kim, Do Hyeong;Jin, Dezhong;Ko, Sung Kwon
    • Natural Product Sciences
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    • v.28 no.2
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    • pp.75-79
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    • 2022
  • As a result of comparing the phenolic components of cinnamon medicines, the total phenolic component content of Cinnamomi Cortex in China was about 2.65 times higher than that of Cinnamomi Cortex in Vietnam. In addition, the total phenolic component content of Vietnamese Cinnamomi Cortex Spissus was about 1.80 times higher than that of Chinese Cinnamomi Cortex Spissus. Meanwhile, Vietnamese Cinnamomi Ramulus showed a content about 3.29 times higher than that of Chinese Cinnamomi Ramulus. Cinnamaldehyde, the main component of cinnamon medicines, showed the same tendency as the total phenolic component content. In terms of the average content of the total phenolic components, Cinnamomi Cortex showed the highest content at 23964 ㎍/g, followed by Cinnamomi Cortex Spissus at 17489 ㎍/g and Cinnamomi Ramulus at 5435.8 ㎍/g. These results showed that Cinnamomi Cortex and Cinnamomi Cortex Spissus with stem bark as usage sites had about 3.22 to 4.41 times higher content of phenolic components than Cinnamomi Ramulus with young branches as usage sites.

Design of Embedded Platform based on Android (안드로이드 기반 임베디드 플랫폼 설계)

  • Yoon, Chan-Ho;Kim, Gwang-Jun;Jang, Chang-Soo
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.10
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    • pp.1545-1552
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    • 2013
  • This paper presents an implementation of embedded platform based ARM A8-cortex processor for android supporting. The development board for S5PV210 is a platform that is suitable for code development of SAMSUNG's S5PV210 32bit RICS micro controller(ARMv7) architecture for hand-held device and general applications. Embedded platform development board offers various function and high efficiencies. In addition to the high performance, the embedded platform offers low current consumption, ensuring low costs and power.

Applications of Prescriptions Including Anemarrhenae Rhizoma and Phellodendri Cortex in Dongeuibogam (동의보감(東醫寶鑑) 중(中) 지모(知母)와 황백(黃柏)이 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察))

  • Sung, See-Yeol;Kook, Yoon-Bum
    • Herbal Formula Science
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    • v.19 no.1
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    • pp.1-22
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    • 2011
  • Objectives : This study was performed to investigate applications of 122 prescriptions including Anemarrhenae Rhizoma and Phellodendri Cortex in Dongeuibogam. Methods : 122 prescriptions including Anemarrhenae Rhizoma and Phellodendri Cortex which have been used separately or concurrently in Oriental Medicine for a long time as a treatment for various disease in Dongeuibogam were studied through order of frequency, symptoms, dosages, and etc. Results : 1. 19(15.57%) prescriptions are recorded in fatigue chapter, 11(9.02%) in mental or emotional disorder as a result of repressed anger or stress chapter, 9(7.38%) in urine and cough chapters respectively and 8(6.56%) in eyes, ears and glycosuria chapters respectively, which are arranged in order of frequency. 2. Burning stress resulted from Yin deficiency treat herbs are ranked top, Yin deficiency treat herbs, dim eyes, Yin-yang deficiency treat herbs, kidney function deficiency treat herbs are ranked in order of frequency among 78 symptoms in prescriptions including Anemarrhenae Rhizoma and Phellodendri Cortex. 3. The dosages of Anemarrhenae Rhizoma which is more used than Phellodendri Cortex are ranged from 5 puns:4 puns ~ 2 nyangs:1 nyang. 1 jeon:5 puns is recorded 3(30.00%), 1 jeon:7 puns is 2 times(20.00%), the others are 1 (10.00%) used among 10 prescriptions including Anemarrhenae Rhizoma and Phellodendri Cortex. 4. The dosages of Anemarrhenae Rhizoma which is used same amount Phellodendri Cortex are ranged from 3 puns each ~ 4 nyangs each, same amount each or unidentified dosages. Same amount each or unidentified dosages each is recorded 36 times(38.71%), 5 puns each is 15 times(16.85%), 1 nyang each is recorded 12 times(13.48%), 0.7 jeon each is recorded 7 times (7.87%) and 1 jeon each is recorded 6 times(6.74%) used among 89 prescriptions including Anemarrhenae Rhizoma and Phellodendri Cortex. 5. The dosages of Anemarrhenae Rhizoma which is less used than Phellodendri Cortex are ranged from 3 puns:1 jeon ~ 4 nyangs:8 nyangs. 1 nyang:2 nyangs is recorded 4(17.39%), 0.5 jeon:1 jeon is 3(13.40%) each, the others are 1 time(4.35%) used among 23 prescriptions including Anemarrhenae Rhizoma and Phellodendri Cortex. 6. The less using dosage of Anemarrhenae Rhizoma and Phellodendri Cortex has a more percentage of decoctions groups, The more using dosage of Anemarrhenae Rhizoma and Phellodendri Cortex has a more percentage of the other groups except decoctions. The less using prescriptions have an effects of controlling yin and blood deficiency, enhancing Qi, etc, as a whole. The more using prescriptions as a form of compound powder have an effects in incurableness disease, chronic diseases, and etc. Conclusions : The 122 prescriptions including Anemarrhenae Rhizoma and Phellodendri Cortex in Dongeuibogam are mainly composed of Gamree-hwan, Samool-tang, Naebo-hwan, Sagoonja-tang and Gobangpoong-tang, and etc.

Nonlinearity in the Somatosensory Cortex Response to Vibrotactile Stimulator in fMRI (기능성 자기공명영상에서 진동자극에 대한 감각피질의 비선형성)

  • Lee, Hyun-Sook
    • Progress in Medical Physics
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    • v.17 no.3
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    • pp.159-166
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    • 2006
  • The nonlinearity of hemodynamic response in the somatosensory cortex was investigated with vibrotactile stimulation. The stimuli consisted of a train of 25 Hz, each tasting five different duration periods, 2 s, 4 s, 8 s 12 s, or 16 s with 20 sec periods of no vibration in a pseudo-random order. In order to understand the linearity on the change of stimulus duration for somatosensory cortex, two different tests- checking the linearity of system and finding the impulse response function from gamma-variate function were applied to analyze the hemodynamic response functions. They have produced nearly same results. The BOLD response in the somatosensory cortex Is nonlinear for stimuli of less than 8 seconds, but nearly linear for stimuli greater than 8 seconds. The amplitude, area, TTP, and FWHM as functions of the stimulus duration were calculated and showed a significant downward trend with Increasing stimulus duration for the amplitude and the area. It supports the ranges of nonlinearity are less than 8 seconds.

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Moutan Cortex Radicis contributes to the chemotaxis of eosinophils and secretion of cytokines in A549 human epithelial cells (목단피(牧丹皮)가 천식(喘息)유발 cytokine 분비와 호산구 chemotaxis에 미치는 영향)

  • Moon, Sung-Hun;Jung, Sung-Ki;Rhee, Hyung-Koo;Jung, Hee-Jae
    • The Journal of Internal Korean Medicine
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    • v.26 no.1
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    • pp.199-212
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    • 2005
  • Objective : Airway inflammation is now regarded as a defining feature of asthma. The importance of eosinophits in the airway inflammation of asthma patients is widely recognized, and eosinophils mobilization in the respiratory epithelium is activated by chemoattractants and cytokines. This study was designed to examine the extent of the ability of Moutan Cortex Radicis to inhibit eosinophil chemotaxis of pulmonary epithelium after allergic stimulation. Material and Methods : Water extracts of Moutan Cortex Radicis and pulmonary epithelial cell lines A549(human type II-like epithelial cells) and human eosinophils were used. Cytotoxic effects of Moutan Cortex Radicis were estimated via MTS assay, and the effects of Moutan Cortex Radicis on chemokines from prestimulated A549 cells were estimated by sandwich ELISA and RT-PCR. Chemotaxis assay on prestimulated eosinophils treated with Moutan Cortex Radicis. was conducted Result : In this study we demonstrated that $TNF-{\alpha}$ and IL-4, $IL-1{\beta}$ induced the accumulation of chemokines' mRNA in the pulmonary epithelial cell lines A549 in a dose-dependent manner. Chemokines of eotaxin, ICAM-1, YCAM-1, IL-8, IL-16 were inhibited by Moutan Cortex Radicis in a dose dependent manner, but RANTES showed no inhibition due to Moutan Cortex Radicis. Eosinophil migration was inhibited at high concentrations of Moutan Cortex Radicis. Conculusion : These findings are indicative of supression of chemokines accomplished by Moutan Cortex Radicis treatment, demonstrating the potential therapeutic value of Moutan Cortex Radicis for treating diseases such as asthma.

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A Subthreshold PMOS Analog Cortex Decoder for the (8, 4, 4) Hamming Code

  • Perez-Chamorro, Jorge;Lahuec, Cyril;Seguin, Fabrice;Le Mestre, Gerald;Jezequel, Michel
    • ETRI Journal
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    • v.31 no.5
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    • pp.585-592
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    • 2009
  • This paper presents a method for decoding high minimal distance ($d_{min}$) short codes, termed Cortex codes. These codes are systematic block codes of rate 1/2 and can have higher$d_{min}$ than turbo codes. Despite this characteristic, these codes have been impossible to decode with good performance because, to reach high $d_{min}$, several encoding stages are connected through interleavers. This generates a large number of hidden variables and increases the complexity of the scheduling and initialization. However, the structure of the encoder is well suited for analog decoding. A proof-of-concept Cortex decoder for the (8, 4, 4) Hamming code is implemented in subthreshold 0.25-${\mu}m$ CMOS. It outperforms an equivalent LDPC-like decoder by 1 dB at BER=$10^{-5}$ and is 44 percent smaller and consumes 28 percent less energy per decoded bit.

An implementation of portable gamma ray detection platform using Cortex-A8 (Cortex-A8을 이용한 휴대용 감마선 검출 플랫폼 구현)

  • Seo, Jae-Gil;Lee, Yoon-Ho;Kim, Young-Kil
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.17 no.4
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    • pp.1028-1033
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    • 2013
  • As safety and security systems of shipping logistics are reinforced all over the world, ubiquitous technology-based core technology for safety and security is developing to build the system of logistics security. It is feared that the logistics security system of Korea has a possibility to technically depend on developed countries in the futures. Because the essential skills and equipment to retain security of logistics are not developed. It is urgent to introduce a logistics security system that fully integrates the entire logistics segment in the future. Thus, the necessity of developing the portable radiation detector which can detect gamma-ray nuclide is increasing for reinforcing safety and security systems. In this paper, a research suggests the implementation of portable radiation detector platform using Cortex-A8.

'Experimental Study on the Effects of Lycii Radicis Cortex on Hyperlipidemia' (지골피(地骨皮)가 고지방식이(高脂肪食餌)로 유발(誘發)된 백서(白鼠)의 고지혈증(高脂血症)에 미치는 영향(影響))

  • Lee, Sung-Doo;Park, Soon-Dal;Byun, Joon-Seok
    • The Journal of Internal Korean Medicine
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    • v.19 no.2
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    • pp.347-366
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    • 1998
  • In order to investigate the effect of Lycii Radicis Cortex on hyperlipidemia, experimental studies were performed on hyperlipidemia rats. Hyperlipidemia model (controll group) was induced by 1% cholesterol fed-diet for 8 weeks. Sample I group fed with 1% cholesterol and 4% Lycii Radicis Cortex diet for 8 weeks. Sample II group fed with 1% cholesterol and 8% Lycii Radicis Cortex diet for 8 weeks. The contents of serum total cholesterol, triglyceride, free fatty acid, phospholipid, HDL-cholesterol and LDL-cholesterol were measured, and fat accumulation in liver and the change of elastic and collagenous fiber in aortic wall were observed. The results were summurized as follows ; 1. The content of total cholesterol in the serum compared with control group tended to be decreased in sample group, but did not show a significance. 2. The content of triglyceride in the serum compared with control group tended to be decreased in sample group, and then sample II group showed a significant value. 3. The content of free fat acid in the serum compared with control group tended to be decreased in sample group, and then sample II group showed a significant value. 4. The content of phospholipid in the serum compared with control group tended to be decreased in sample group, but did not show a significance. 5. The content of HDL-cholesterol in the serum compared with control group tended to be increased in sample group, and then sample I group showed a significant value. 6. The content of LDL-cholesterol in the serum compared with control group tended to be decreased in sample group, and then sample I group showed a significant value. 7. The lipophagy in liver compared with control group tended to be decreased in sample group. 8. The change of elastic and collagenous fiber lesion in tunica media of aortic wall, compared with control group tended to be decreased in sample group. According to the above results, it is assumed that Lycii Radicis Cortex has a valid effect on hyperlipidemia. Therefore, it seems to be applicable to the diseases related to hyperlipidemia.

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The Study of Smart Navigation System development for blind people based on Cortex-A8 Platform include Digital Zoom (Digital Zoom기능을 포함한 Cortex-A8 Platform 기반의 시각장애인용 Smart Navigation System개발에 관한 연구)

  • Han, Seung-Hwan;Kim, Young-kil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.10a
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    • pp.289-292
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    • 2012
  • Presently, there is the blind of about 20~300,00 people including didn't register in Korea Usually, they used white stick when they walk outside. There is the blind receiving the help of the guide dog but a small number of blind uses due to many composite problems including the cost problem, and etc. Presently, the guidance service aid long for the blind which is commonly used adheres the RFID tag to the white stick. It remains at the level of the extent of making the cover block and RF communication by using this. The recognition distance is short. This is the actual condition in which it is difficult to determine the location of the clear obstacle and size and form, it doesn't become the help which is actually big in the walk of the blinds. Thus, in this paper, the investigation of 'Smart Portable Navigation System' development of the Cortex-A8 Platform base tries to be handled so that the blinds can walk easily.

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