• Title/Summary/Keyword: Correlation relationships

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Comparative Molecular Field Analyses (CoMFA) on the Mela-nogenesis Inhibitory Activities of Alkyl-3,4-dihydroxybenzoyl Derivatives.

  • Kim, Sang-Jin;Sung, Nack-Do;Lee, Tack-Hyuck
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.225-231
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    • 2003
  • To search and development a new material with superior melanogenesis inhibitory activity, the bioactivities (obs. pl$_{50}$) of alkyl-3,4-dihydroxybenzoyl esters and N-alkyl-3,4-dihydroxybenz-oyl amides as substrate molecules were measured in mouse melanoma cells. And also, we have studied that 3-D QSARs (3 dimensional Quantitative Structure-Activity Relationships) between molecular interaction field of substrates and the bioactivities were analyzed using CoMFA (Comparative Molecular Field Analyses) method. When cross-validation value (q$^2$) is 0.68 at 3 components, the Pearson correlation coefficient ($r^2$) is 0.900. From the basis on the findings, the model was appeared by the contour map such as steric field and electrostatic field relationships between quantitative structure and the bioactivity of the various substrate derivatives. Measured bioactivities (obs. pl$_{50}$) of unknown compounds are very similar to predicted activity (pred. pl$_{50}$) according to the CoMFA model. As the results of prediction, we could conclude that the bioactivities were increased by creation of R$_1$ substitution of 5,5-dime-thylhexoxy, 6,6-dimethylheptyl, 1-amino-6,6-dimethylheptyl group etc and R$_2$ substitution of hydroxy, methyl, methoxy group etc.p etc.

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Drinking-related knowledge, attitude and drinking behaviors of female college students (간호대 여학생의 음주관련 지식, 태도 및 음주행위에 관한 연구)

  • Park, Gyung;Choi, Soon-Hee
    • The Journal of Korean Society for School & Community Health Education
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    • v.13 no.1
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    • pp.23-32
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    • 2012
  • Purpose: This study was to investigate the relationships between drinking-related knowledge, attitude and drinking behaviors of 244 female nursing college students in G city. Methods: This is descriptive research design. Data were collected from September 27th to October 10th, 2010 after obtaining the informed consent from the participants and analyzed using t-test, ANOVA, scheffe' test and pearson's correlation coefficients. Results: The drinking-related knowledge scores were significant differences by grade and club activities. The drinking-related attitude scores were significant differences by source of income. Drinking behaviors were significant differences by school record and club activities. Regarding the relationships between variables, there was a positive relationship between drinking behaviors and drinking-related knowledge or attitude. Conclusion: The drinking-related knowledge score of freshmen or the students involved in club activities was the lowest, and the higher the drinking-related knowledge and attitude were, the higher the drinking behaviors were. Therefore, appropriate drinking prevention education need to be implemented to freshmen or in middle and high school repeatedly.

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Children's cellular phone usage and relationships between the usage and self-efficacy and self-control (초등학생의 휴대전화이용 수준과 자기효능감 및 자기통제력과의 관계연구)

  • Lee, Gyeong-Seon;Lee, Jeong-Hwa
    • Korean Journal of Human Ecology
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    • v.17 no.2
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    • pp.271-278
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    • 2008
  • This study was investigated elementary school children's cellular phone usage and relationships between the usage and their self-efficacy and self-control. The data were collected by boys(101) and girls(155) among 5th grades, boys(125) and girls(177) among 6th grades elementary school in Busan. The data analyzed with the frequency, percentage, mean, SD and t-test, ANOVA, Pearson's correlation in use of SPSS Win 12.0 program. The results from the research can be summarized as follows; First, there was no significant difference in the children's general usage of cellular phone in terms of grade and sex. Second, it was found in a couple of significant difference in the subcategories of the usage according to grades. The 6th grades children is higher scores than 5th grades in the 'control of cellular phone usage' and 'living trouble'. Third, there was correlated negatively between cellular phone usage and the children's self-efficacy/self-control.

Relationship between Depression and Resilience among Children with Nephrotic Syndrome (신증후군 환아의 극복력과 우울의 관계분석)

  • 김동희;유일영
    • Journal of Korean Academy of Nursing
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    • v.34 no.3
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    • pp.534-540
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    • 2004
  • Purpose: The purposes of this study were to describe the relationship between depression and resilience and to identify variables associated with depression among children with nephrotic syndrome. Method: Data was collected from 45 children who were registered at one hospital in Seoul. The criteria for sample selection were 10 to 15 year-old children who were diagnosed at least 6 month prior. The instruments included a self-reported questionnaire on resilience by Kim, CDI by Beck, and MBRI by Kwak. Descriptive, Pearson correlation and multiple regression analyses were done. Result: The mean score of depression was 11.44 (range:0-54) and resilience was 97.47 (range:32-128). There were significant positive relationships between depression and age (r=0.302, p<.005) and academic achievement (r=-0.318, p<.005). In addition, negative relationships between depression and maternal attitude (r=-0.412, p<.001) and resilience (r=-0.649, p<.001) occurred. The results of multiple regression analysis showed that maternal behavior (${\beta}$=-0.421, p<.005) and resilience (${\beta}$=-0.639, p<.001) were related to depression. Conclusion: Children with higher resilience and with an affectionate mother were less depressed. Thus, it is important to identify strengths of children and help them to increase resilience and implement parenting and counseling programs for parents' of these children. Similar studies with children with other chronic illnesses are needed.

The Relationships between the Parenting Stress of Mothers and the Adjustment of Young Children in Child-Care Centers (어머니의 양육스트레스와 영유아의 교육기관 적응의 관계)

  • Lee, Ja Hyun;Wui, Yeong Hee
    • Korean Journal of Child Studies
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    • v.33 no.5
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    • pp.139-161
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    • 2012
  • The purpose of this study was to analyze the relationships of mothers' parenting stress and young children's adjustment to the child care centers they attend. The subjects for this study comprised 401 young children from 1 to 4 years of age from 11 child care centers in C-si, Chungnam, and their mothers. The results of this study were as follows : First, there were no significant differences in the parenting stress of mothers related to whether they were working or not, the age of the children nor their gender Second, there were no significant differences in the adjustment of young children to their child care center related to their mothers' work status nor age of the children themselves. However, there was a significant difference in relation to the gender of the young children in that girls were better in their adjustment to the child care center than boys. Third, a negative correlation appeared between mothers' parenting stress and their young children's adjustment to the child care center in that the higher maternal parenting stress was, the greater the difficulties for their young children in their adjustment to the child care center. There were significant negatively correlations between most sub-factors of maternal parenting stress and the adjustment of those children to the child care center.

The Relationships Among Collectivism, Role Conflict, and the Organizational Commitment of Teachers in Kindergartens and Childcare Centers (유아교육.보육기관 교사의 집단주의 및 역할갈등이 조직몰입에 미치는 영향)

  • Gwon, Gi-Nam;Min, Ha-Yeoung
    • Journal of Families and Better Life
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    • v.28 no.3
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    • pp.129-137
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    • 2010
  • This study investigated the relationships among collectivism, role conflict, and the organizational commitment of teachers in kindergartens and childcare centers. The subjects were 190 teachers who worked in a kindergarten or a childcare center in Daegu and in Gyoungbuk Province. Questionnaires were used to investigate collectivism, role conflict, and organizational commitment by self-reports from teachers. The collected data were analyzed by factor analysis, Pearson's correlation, and stepwise multiple regression using SPSS Win 15.0. The results were as follows. (1) Collectivism was positively associated with the organizational commitment of the teachers. (2) Role conflict was negatively associated with the organizational commitment of the teachers. Among the different types of role conflict, teaching profession conflict, co-worker conflict, and administration conflict were negatively associated with organizational commitment. (3) Role conflict was a better predictor of organizational commitment than collectivism. Additionally, administration conflict as a type of role conflict was a better predictor of organizational commitment than collectivism.

Health-related Quality of Life of Children and Adolescents after Hematopoietic Stem Cell Transplantation

  • Hwang, Yu Min;Bang, Kyung-Sook
    • Child Health Nursing Research
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    • v.26 no.4
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    • pp.402-410
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    • 2020
  • Purpose: This study aimed to determine the level of health-related quality of life (HRQoL) of children and adolescents who received hematopoietic stem cell transplantation (HSCT) and to examine factors influencing HRQoL. Methods: This cross-sectional descriptive study involved 85 participants aged 10 to 19 years who received treatment from 3 months to 5 years after HSCT. Symptom experiences, stress and coping, self-esteem, social support, and HRQoL were measured. Descriptive analysis, the independent t-test, one-way analysis of variance, Pearson correlation analysis, and stepwise multiple regression were used for data analysis. Results: The mean HRQoL score was 72.26 points out of 100. HRQoL showed statistically significant correlations with symptom experiences, stress, self-esteem, social support, satisfaction with peer relationships, and perceived attentiveness of the medical team. The most influential predictors of HRQoL were symptom experiences (β=-.51, p<.001) and satisfaction with peer relationships (β=.32, p<.001). Conclusion: The experiences of different symptoms by children and adolescents who receive HSCT must be considered. In addition, nursing interventions, such as self-help meetings with peer groups, should be provided to improve their HRQoL.

Investigating the Relationships among Substantive Understanding, Scientific Literacy and Learning Intention in CSILE-based Inquiry Learning and Inquiry Ability (CSILE 기반의 탐구학습에서 지식의 이해, 과학적 소양, 학습 의도 및 탐구력의 관련성 규명)

  • Kim, Jee-Il
    • The Journal of Korean Association of Computer Education
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    • v.7 no.5
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    • pp.57-70
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    • 2004
  • This study is the subsequent study that has the objectives examining the relationships among 'substantive understanding', 'scientific literacy' and 'learning intention' in computer supported intentional learning environments and inquiry ability, variables for affecting knowledge construction derived from the finding out of the former study. As a result, the current study confirmed in CSILE the close correlation between 'the learning intention for scientific inquiry' and 'substantive understanding', between 'the learning intention for scientific inquiry' and 'scientific literacy'. Another result showed that 'scientific literacy' was the most significant predictor on inquiry ability. Base on the result of this study, the present researcher is about to make suggestions to stimulate learners' scientific literacy in CSILE-based inquiry learning.

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Relationships Among Emotional Support from Social Network, Ego-Resiliency, and Role Conflict of Teachers in Kindergartens and Day Care Centers (유아교육기관 교사의 사회적 정서 지지와 자아탄력성 및 역할갈등간 관계)

  • Min, Ha-Yeoung;Gwon, Gi-Nam
    • Journal of Families and Better Life
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    • v.27 no.5
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    • pp.91-99
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    • 2009
  • This study investigates the relationships among emotional support from social network, ego-resiliency, and role conflict of teachers in kindergartens and day care centers. The subjects were 192 teachers who worked in kindergartens or child care centers in Daegu and Gyeongbuk Province. Questionnaires, which require self-report by teachers, were used to investigate the emotional support from social network, ego-resiliency, and role conflict. The collected data were analyzed by Pearson's correlation, single and multiple regressions, using SPSS Win 15.0. The results are as follows. (1) Emotional support from social network and ego-resiliency was negatively associated with the role conflict of teachers in kindergartens and day care centers. (2) Emotional support from social network was positively associated with ego-resiliency. (3) Emotional support from social network partly exerted indirect effects on role conflict mediated by ego-resiliency. But direct effect of emotional support from social network on role conflict was more than the indirect effect. These results indicate that a higher level of emotional support from social network is more likely to lower role conflict of teachers.

Relationships between Physical Activity, Health Status, and Quality of Life of University Students (대학생의 신체활동량, 건강상태 및 삶의 질과의 관계)

  • Park, Jee Yeon;Kim, Na Hyun
    • Journal of Korean Public Health Nursing
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    • v.27 no.1
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    • pp.153-165
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    • 2013
  • Purpose: The purpose of this study was to identify the relationships between physical activity, health status, and quality of life (QOL) of University students. Methods: The research design was based on a descriptive research design model. This study sample consisted of 183 K University students in D city. Data was collected from December 2012 to January 2013 and analyzed with descriptive statistics (frequency, percentage, analysis of variance (ANOVA), t-test, and Pearson's correlation analysis) using SPSS 19.0. Subjects completed questionnaires on their demographics, physical activity, health status, and QOL. Results: The overall physical activity of participants was $2529.40{\pm}5057.896$ min/week on average. The average health status was $28.66{\pm}6.3$ and the average physical health and mental health were $16.45{\pm}3.955$ and $12.31{\pm}3.446$, respectively. The overall degree of QOL was $3.429{\pm}0.379$. A positive relationship existed between moderate and vigorous activity and health status. In addition, QOL positively correlated with physical health (under health status). However, physical activity was not related with both mental health (under health status) and QOL. Conclusion: Based on the results of this study, health educational programs are needed to promote sufficient physical activity in university students.