• Bulletin of the Korean Chemical Society
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• v.23 no.6
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• pp.872-879
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• 2002

One of the improtant characteristics of core-shell type nanoparticles is the long-term storage and reuse as an aqueous injection solution when required. For this reason, reconstruction of lyophilized core-shell type nanoparticles is considered to be essential . BAB type triblock copolymers differ from AB type diblock copolymers, which contain the A block as a hydrophilic part and the B block as a hydrophobic part. by not being easily redistributed into phosphate-buffered saline (PBS, pH 7.4, 0.1 M). Therefore, lyophilized core-shell type nanoparticles of CEC triblock copolymer were reconstituted using a somication process with a bar-type sonicator in combination with a freezing-thawing process. Soncation for 30s only resuspended CEC nanoparticles in PBS; their particle size distribution showed a monomodal pattern with narrow size distribution. The bimodal size distribution pattern and the aggregates were reduced by further sonication for 120 s but these nanoparticles showed a wide size distribution. The initial burst of drug release was increased by reconstitution process. The reconstitution of CEC core-shell type nanoparticles by freezing-thawing resulted in trimodal distribution pattern and formed aggregates, although freezing-thawing process was easier than sonication . Drug release form CEC nanoparticles prepared by freezing-thawing was slower than from the original dialysis solution. Although core-shell typenanoparticles of CEC triblock copolymers were not easily performed. Cytotoxicity testing of core-shell type nanoparticles of CEC-2 triblock copolymers containing clonazepam (CNZ) was performed using L929 cells. Cytotoxicity of CNZ was decreased by incorporation into nanoparticles.

• Bulletin of the Korean Chemical Society
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• v.34 no.10
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• pp.2865-2870
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• 2013

Ni-Ag core-shell nanoparticles were synthesized by polyol process and microemulsion technique successfully. In the polyol process, a chemical reduction method for preparing highly dispersed pure nickel and Ag shell formation have been reported. The approach involved the control of reaction temperature and reaction time in presence of organic solvent (ethylene glycol) as a reducing agent for Ag cation with poly(vinyl-pyrrolidone) (PVP. Mw = 40000) as a capping agent. In microemulsion method, the emulsion was prepared by water/cetyltrimetylammonium bromide (CTAB)/cyclohexane. The size of microemulsion droplet was determined by the molar ratio of water to surfactant (${\omega}_o$). The core-shell formation along with the change in structural phase and stability against oxidation at high temperature heat treatments of nanoparticles were investigated by X-ray diffraction and TEM analysis. Under optimum conditions the polyol process gives the Ni-Ag core-shell structures with 13 nm Ni core covered with 3 nm Ag shell, while the microemulsion method gives Ni core diameter of 8 nm with Ag shell of thickness 6 nm. The synthesized Ni-Ag core-shell nanoparticles were stable against oxidation up to $300^{\circ}C$.

• Nuclear Engineering and Technology
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• v.33 no.4
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• pp.441-456
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• 2001

ABB-CE＇s regionalization methodology for the core inlet flow distribution map is reviewed. This methodology merges the test data of fuel assembly locations which are either in symmetry or strongly correlated with others. It increases the number of available test data for each regional flow factor It makes up effectively for the deficiency due to limited number of test data. It also contributes to making the core inlet flow distribution smoother not only locally but also over the entire core, and to relieving the impacts of test errors that may happen due to some do- calibrated local pressure measurement taps. As a result, the core inlet How distribution data becomes more statistically useful and thus the conservatism involved in handling the core inlet flow factors for the thermal margin analysis is expected to be reduced. Meanwhile, the regionalized map may lose the unique local characteristics in core inlet flow distribution too much. By an alternative approach introduced in the present work, it is shown that such a disadvantage can be mitigated somewhat if the engineering judgement is made more

• Preventive Nutrition and Food Science
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• v.4 no.2
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• pp.145-151
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• 1999

Apolipoprotein B-100 (apo B-100) is an important component in plasma low density lipoproteins (LDL). It function as the ligand for the LDL receptor in peripheral cells. The LDLs are removed from the circulation by both high-affinity receptor-mediated and receptor-independant pathways. LDLs are heterogeneous in their lipid content, size and density and certain LDL subspecies increase risk of atherosclerosis due to differences in the conformation of apo B in the particle. In the present study , surface and core peptide fraction of Apo B-100 have been characterized by comparing peptide-mapping and fluorescence spectroscopy. Surface fragments of apo B-100 were generated by digestion of LDL with either trypsin , pronase, or pancreatin elastase. Surface fractions were fractionated on a Sephadex G-50 column. The remaining core fragments were delipidated and redigested with the above enzymes, and the resulting core peptides were compared with surface peptides. Results from peptide-mapping by HPLC showed pronase-digestion was more extensive than trypsin -digestion to remove surface peptide fraction from LDL. Fluorescence spectra showed that core fractions contained higher amount of tryptophan than surface fractions, and it indicated that core fraction wa smore hydrophobic than surface fractions. A comparison of the behavior of the core and surface provided informations about the regions of apo B-100 involved in LDL metabolism and also about the structural features concerning the formation of atherosclerosis.

• IEIE Transactions on Smart Processing and Computing
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• v.4 no.2
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• pp.71-77
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• 2015

Upcoming ground-breaking applications for always-on tiny interconnected devices steadily demand two-fold features of processor cores: aggressively low power consumption and enhanced performance. We propose implementation of a novel superscalar low-power processor core with a low supply voltage. The core implements intra-core low-power microarchitecture with minimal performance degradation in instruction fetch, branch prediction, scheduling, and execution units. The inter-core lockstep not only detects malfunctions during low-voltage operation but also carries out software-based recovery. The chip incorporates a pair of cores, high-speed memory, and peripheral interfaces to be implemented with a 65nm node. The processor core consumes only 24mW at 350MHz and 0.68V, resulting in power efficiency of $80{\mu}W/MHz$. The operating frequency of the core reaches 850MHz at 1.2V.

• Bulletin of the Korean Chemical Society
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• v.30 no.5
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• pp.1184-1186
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• 2009

• Restorative Dentistry and Endodontics
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• v.29 no.2
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• pp.191-199
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• 2004

The purposes of this study were to estimate the material properties of the recently developed domestic composite resins for core filling material (Chemical, Dual A, Dual B；Vericom, Korea) and to compare them with other marketed foreign products (CorePaste, Den-Mat, USA；Ti-Core, Essential Dental Systems, USA；Support. SCI-Pharm. USA). Six assessments were made：working time. setting time. depth of polymerization. flexural strength. bonding strength. and marginal leakage. All items were compared to ISO standards. All domestic products satisfied the minimum requirements from ISO standards (working time：above 90 seconds. setting time：within 5 minutes). and showed significantly higher flexural strength than Core Paste. Dual A and B could. especially. reduce the setting time to 60 seconds when cured with $600mW/cm^2$ light intensity. All experimental materials showed 6 mm depth of polymerization. Bond strengths of Ti-Core and Dual B materials were significantly higher than the other materials. Furthermore. three domestic products and Ti-Core could reduce the microleakage effectively.

• Nuclear Engineering and Technology
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• v.50 no.5
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• pp.673-682
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• 2018

One of the most widely used methods to estimate core damage during a nuclear power plant accident is containment radiation measurement. The evolution of severe accidents is extremely complex, leading to uncertainty in the containment dose rate (CDR). Therefore, it is difficult to accurately determine core damage. This study proposes to conduct uncertainty analysis of CDR for core damage assessment. First, based on source term estimation, the Monte Carlo (MC) and point-kernel integration methods were used to estimate the probability density function of the CDR under different extents of core damage in accident scenarios with late containment failure. Second, the results were verified by comparing the results of both methods. The point-kernel integration method results were more dispersed than the MC results, and the MC method was used for both quantitative and qualitative analyses. Quantitative analysis indicated a linear relationship, rather than the expected proportional relationship, between the CDR and core damage fraction. The CDR distribution obeyed a logarithmic normal distribution in accidents with a small break in containment, but not in accidents with a large break in containment. A possible application of our analysis is a real-time core damage estimation program based on the CDR.

• Nuclear Engineering and Technology
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• v.55 no.1
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• pp.144-155
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• 2023

The core catcher is used as a passive safety system in new generation nuclear power plants to create a space in the containment for the placing and cooling of the molten corium under various severe accidents. This research investigates the role of the core catcher in the VVER-1000 reactor containment system in mitigating the effects of core meltdown under various severe accidents within the context of the Ex-vessel Melt Retention (EVMR) strategy. Hence, a comparison study of three severe accidents is conducted, including Station Black-Out (SBO), SBO combined with the Large Break Loss of Coolant Accident (LB-LOCA), and SBO combined with the Small Break Loss of Coolant Accident (SB-LOCA). Numerical comparative simulations are performed for the aforementioned scenario with and without the EX-vessel core-catcher. The results showed that considering the EX-Vessel core catcher reduces the amount of hydrogen by about 18.2 percent in the case of SBO + LB-LOCA, and hydrogen production decreases by 12.4 percent in the case of SBO + SB-LOCA. Furthermore, in the presence of an EX-Vessel core-catcher, the production of gases such as CO and CO2 for the SBO accident is negligible. It was revealed that the greatest decrease in pressure and temperature of the containment is related to the SBO accident.

• Steel and Composite Structures
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• v.44 no.4
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• pp.519-529
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• 2022

Sandwich structures with the superior mechanical properties such as high stiffness and strength-to-weight ratio, good thermal insulation, and high energy absorption capacity are used today in aerospace, automotive, marine, and civil engineering industries. These structures are composed of moderately stiff, thin face sheets that withstand the majority of transverse and in-plane loads, separated by a thick, lightweight core that resists shear forces. In this research, the finite element technique is used to simulate a sandwich panel with a truss core under axial compressive stress using ABAQUS software. A review of past experimental studies shows that the bondline between the core and face sheets plays a vital role in the critical failure load. Therefore, this modeling analyzes the damage initiation modes and debonding between face sheet and core by cohesive surface contact with traction-separation model. According to the results obtained from the modeling, it can be observed that the adhesive stiffness has a significant influence on the critical failure load of the specimens. To achieve the full strength of the structure as a continuum, a lower limit is obtained for the adhesive stiffness. By providing this limit stiffness between the core and the panel face sheets, sudden failure of the structure can be prevented.