• Title/Summary/Keyword: Core simulation

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Quantitative Structure-Activity Relationships and Molecular Docking Studies of P56 LCK Inhibitors

  • Bharatham, Nagakumar;Bharatham, Kavitha;Lee, Keun-Woo
    • Bulletin of the Korean Chemical Society
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    • v.27 no.2
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    • pp.266-272
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    • 2006
  • Three-dimensional quantitative structure-activity relationship (3D-QSAR) models were developed for 67 molecules of 2-amino-benzothiazole-6-anilide derivatives against lymphocyte-specific protein tyrosine kinase (P56 LCK). The molecular field analysis (MFA) and receptor surface analysis (RSA) were employed for QSAR studies and the predictive ability of the model was validated by 15 test set molecules. Structure-based investigations using molecular docking simulation were performed with the crystal structure of P56 LCK. Good correlation between predicted fitness scores versus observed activities was demonstrated. The results suggested that the nature of substitutions at the 2-amino and 6-anilide positions were crucial in enhancing the activity, thereby providing new guidelines for the design of novel P56 LCK inhibitors.

A Study on the Core Equivalent Stiffness Modeling Technique for FSI Analysis of High-Rise Buildings Under Wind Load (풍하중을 받는 초고층건물의 FSI 해석을 위한 코어 삽입 등가 강성 모델링 기법에 관한 연구)

  • Oh, Kang-Hwan;Jeon, Doo-jin;Han, Sang-Eul
    • Journal of Korean Association for Spatial Structures
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    • v.17 no.3
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    • pp.65-73
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    • 2017
  • Recently, the trend is emerging a variety of irregular tall buildings. It is important to design the building for lateral load according to this trend. Fluid Structure Interaction(FSI) simulation can be performed to understand the vibrations of the structure against dynamic wind loads. In order to make the physical characteristics of the actual structure and the analytical model the same, we studied core inserting equivalent stiffness modeling method. As a result of this analysis, the stiffness of the structure can be set similar to that of the two axes of the structure, and turbulence can be reproduced through the acceleration tendency.

Finite Element Study of Ferroresonance in single-phase Transformers Considering Magnetic Hysteresis

  • Beyranvand, Morteza Mikhak;Rezaeealam, Behrooz
    • Journal of Magnetics
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    • v.22 no.2
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    • pp.196-202
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    • 2017
  • The occurrence of ferroresonance in electrical systems including nonlinear inductors such as transformers will bring a lot of malicious damages. The intense ferromagnetic saturation of the iron core is the most influential factor in ferroresonance that makes nonsinusoidal current and voltage. So the nonlinear behavior modeling of the magnetic core is the most important challenge in the study of ferroresonance. In this paper, the ferroresonance phenomenon is investigated in a single phase transformer using the finite element method and considering the hysteresis loop. Jiles-Atherton (JA) inverse vector model is used for modeling the hysteresis loop, which provides the accurate nonlinear model of the transformer core. The steady-state analysis of ferroresonance is done while considering different capacitors in series with the no-load transformer. The accurate results from copper losses and iron losses are extracted as the most important specifications of transformers. The validity of the simulation results is confirmed by the corresponding experimental measurements.

Magnetic Saturation Effect on the Rotor Core of Synchronous Reluctance Motor

  • Kim, Ki-Chan
    • Journal of Electrical Engineering and Technology
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    • v.6 no.5
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    • pp.634-639
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    • 2011
  • This paper presents a study on the design parameters that consider the magnetic saturation effect in a rotor core of a synchronous reluctance motor. Two important design parameters in a rotor are selected to analyze the saturation effect of a synchronous reluctance motor, particularly in a rotor core. The thickness of the main segment, which is the main path of the d-axis flux, and the end rip, which affects the q-axis flux, are analyzed using the d-axis and q-axis inductances. Moreover, the characteristics of torque and torque ripple when magnetic saturation takes place are analyzed. The saturation effect is verified by comparing the reluctance torque between the experiment and FEM simulation.

Design of Inductor Simulation for LDC Test-Bed Using Saturable Core (Saturable Core를 이용한 LDC Test-Bed의 인덕터 시뮬레이션 설계)

  • Sung, Won-Yong;Kim, Yun-Sung;Ahn, Jung-Hoon;Lee, Byoung-Kuk
    • Proceedings of the KIPE Conference
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    • 2012.07a
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    • pp.97-98
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    • 2012
  • 본 논문은 코어의 다양한 재질, 단면적으로 인한 인덕터의 특성변화를 시뮬레이션 하기 위해 PSIM의 Saturable Core를 이용하여 인덕터 구성을 한다. 특히 전기자동차의 LDC (Low-voltage DC-DC Converter)용 인덕터의 Test-Bed를 구성하고, 인덕터 설계 시 코어의 변화에 따른 인덕터 특성의 변화를 시뮬레이션을 통해 구현한다. 또한 설계된 인덕터를 시뮬레이션에 구현하여 비 이상적인 특성을 가지는 인덕터를 구현하고, 이를 통해 시뮬레이션을 통한 인덕터 검증의 필요성을 제시한다.

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MC21/CTF and VERA multiphysics solutions to VERA core physics benchmark progression problems 6 and 7

  • Kelly, Daniel J. III;Kelly, Ann E.;Aviles, Brian N.;Godfrey, Andrew T.;Salko, Robert K.;Collins, Benjamin S.
    • Nuclear Engineering and Technology
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    • v.49 no.6
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    • pp.1326-1338
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    • 2017
  • The continuous energy Monte Carlo neutron transport code, MC21, was coupled to the CTF subchannel thermal-hydraulics code using a combination of Consortium for Advanced Simulation of Light Water Reactors (CASL) tools and in-house Python scripts. An MC21/CTF solution for VERA Core Physics Benchmark Progression Problem 6 demonstrated good agreement with MC21/COBRA-IE and VERA solutions. The MC21/CTF solution for VERA Core Physics Benchmark Progression Problem 7, Watts Bar Unit 1 at beginning of cycle hot full power equilibrium xenon conditions, is the first published coupled Monte Carlo neutronics/subchannel T-H solution for this problem. MC21/CTF predicted a critical boron concentration of 854.5 ppm, yielding a critical eigenvalue of $0.99994{\pm}6.8E-6$ (95% confidence interval). Excellent agreement with a VERA solution of Problem 7 was also demonstrated for integral and local power and temperature parameters.

The Analysis for the Simulational Characteristics of the Electronic CT & PT using EMTP (EMTP를 이용한 전자식 CT, PT의 시뮬레이션 특성 분석)

  • Shin Jung Eun;Kim Jae Chul;Song Seung Youp;Kwon Young Mok;Kim On Suk;Choo Dong Wook
    • Proceedings of the KIEE Conference
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    • summer
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    • pp.310-312
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    • 2004
  • Generally, instrument transformer of the core type have been used for measuring current. Because instrument transformer has defects, electronic instrument was appeasred. This paper is introduced a basic concept and thoery of electronic instrument and described the the simulation of core type CT and no saturation CT. The evaluation of CT models implemented using EMTP(Electro Magnetic Transients Program) was carried out. The result of comparison both core type CT and no saturation CT are presented.

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Nonlinear damping and forced vibration analysis of laminated composite plates with composite viscoelastic core layer

  • Youzera, Hadj;Ali, Abbache;Meftah, Sid Ahmed;Tounsi, Abdelouahed;Hussain, Muzamal
    • Steel and Composite Structures
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    • v.44 no.1
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    • pp.91-104
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    • 2022
  • The purpose of the present work is to study the parametric nonlinear vibration behavior of three layered symmetric laminated plate. In the analytical formulation; both normal and shear deformations are considered in the core layer by means of the refined higher-order zig-zag theory. Harmonic balance method in conjunction with Galerkin procedure is adopted for simply supported laminate plate, to obtain its natural and damping properties. For these aims, a set of complex amplitude equations governed by complex parameters are written accounting for the geometric nonlinearity and viscoelastic damping factor. The frequency response curves are presented and discussed by varying the material and geometric properties of the core layer.

Numerical evaluation of hypothetical core disruptive accident in full-scale model of sodium-cooled fast reactor

  • Guo, Zhihong;Chen, Xiaodong;Hu, Guoqing
    • Nuclear Engineering and Technology
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    • v.54 no.6
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    • pp.2120-2134
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    • 2022
  • A hypothetical core destructive accident (HCDA) has received widespread attention as one of the most serious accidents in sodium-cooled fast reactors. This study combined recent advantages in numerical methods to realize realistic modeling of the complex fluid-structure interactions during HCDAs in a full-scale sodium-cooled fast reactor. The multi-material arbitrary Lagrangian-Eulerian method is used to describe the fluid-structure interactions inside the container. Both the structural deformations and plug rises occurring during HCDAs are evaluated. Two levels of expansion energy are considered with two different reactor models. The simulation results show that the container remains intact during an accident with small deformations. The plug on the top of the container rises to an acceptable level after the sealing between the it and its support is destroyed. The methodology established in this study provides a reliable approach for evaluating the safety feature of a container design.

Real-time Scheduling on Heterogeneous Multi-core Architecture for Energy Conservation of Smart Mobile Devices (스마트 모바일 장치의 에너지 보존성을 높이기 위한 비대칭 멀티 코어 기반 실시간 태스크 스케쥴링)

  • Lim, Sung-Hwa
    • Journal of Digital Contents Society
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    • v.19 no.6
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    • pp.1219-1224
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    • 2018
  • Nowaday, smart mobile devices on Internet of Things are required to process and deliver greate amount of data in real-time. Therefore, heterogeneous mult-core architecture such the big.LITTLE core architecture, which shows high energy conservation while guaranteeing high performance, are widely employed on up to date smart mobile devices. The LITTLE cores should be highly utilized to gain higher energy conservation because LITTLE cores have much higher energy efficiency than big cores. In this paper, we propose a core selection algorithm, which tries to firstly assign a real-time task on a LITTLE core rather a big core while the task can be finished within its own deadline. We also perform simulation as performance evaluation to show that our proposed algorithm shows higher energy conservation while guaranteeing the required performance.