• Bulletin of the Korean Chemical Society
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• v.31 no.11
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• pp.3333-3340
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• 2010

A three dimensional pharmacophore model was generated for the molecules which are responsible for anti-inflammatory activities targeting Interleukin-2 inducible tyrosine kinase (Itk). 16 structurally diverse molecules were selected as training set to generate the hypotheses using Discovery Studio v2.1. The best hypothesis, Hypo1, comprises two hydrogen bond acceptor (HBA), one hydrophobic aromatic (HA), one ring aromatic (RA) and shows high cost difference (63.71), high correlation coefficient (0.97) as well as low RMS deviation (0.81). Hypo1 has been further validated toward a test set, decoy set and Fischer's randomization method. Furthermore, Hypo1 was used to screen NCI and Maybridge databases. Finally, 2 hit molecules were identified as potential leads against Itk, which may be useful for future drug development.

• Journal of Broadcast Engineering
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• v.10 no.3
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• pp.392-400
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• 2005

Highly integrated MPEG-4@SP video compression engine, VideoCore, is proposed for mobile application. The primary components of video compression require the high memory bandwidth since they access the external memory frequently. They include motion estimation, motion compensation, quantization, discrete cosine transform, variable length coding, and so on. The motion estimation processor adopted in VideoCore utilizes the small-size local memories such that the video compression system accesses external memory as less frequently as possible. The entire video compression system is divided into two distinct sub-systems: the integer-unit motion estimation part and the others, and both operate concurrently in a pipelined architecture. Thus the VideoCore enables the real-time high-quality video compression with a relatively low operation frequency.

• Journal of Convergence for Information Technology
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• v.9 no.2
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• pp.100-107
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• 2019

The purpose of this study is to develop an evaluation model to measure the core competences of actual play workers by exploring what competences are necessary for them to provide quality play. Based on literature review, we selected five core competences : knowledge of play, program development, understanding play culture, creativity, and information sharing & applying. In order to achieve the research purpose end, a two-round Delphi survey was conducted on 10 play and education experts. The findings drew scholarly consensus on the competences of play workers to have and proposed basic data by developing competences evaluation model to measure them. Each of the key competences has three sub-conpetences, each of which included two behavior elements. Furthermore, this study presented future research directions so that play can be voluntarily planned and supported in a social and cultural context.

• Journal of Korean Academy of Nursing
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• v.53 no.4
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• pp.412-425
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• 2023

Purpose: Nurses play an important role in ensuring patient rehabilitation and are involved in all aspects of multidimensional rehabilitation. Therefore, strengthening rehabilitation nursing education is vital to ascertain high-quality rehabilitation and optimum outcomes. This study examined the effectiveness of a new teaching reform-a modified Six-Sigma-based training program-against a conventional educational program on rehabilitation specialist nurses' core competencies, post-training performance, and satisfaction. Methods: A quasi-randomized controlled trial was conducted to assess the effectiveness of the modified training program. We recruited 56 learners from the 2020 training course at the Hunan Rehabilitation Specialist Nurse Training Base as the control group. Sixty learners from the base's 2021 training course were recruited as the intervention group. Data were collected in a consistent manner from both groups after the training program was implemented. Results: Those who underwent the modified training program showed better improvement in all core competencies than those who underwent the conventional training program (p < .05); the scores for theoretical knowledge, clinical nursing lectures, reviews, and nursing case management improved significantly following the teaching reform (p < 0.05). Further, overall satisfaction as well as base management and theoretical teaching satisfaction improved significantly (p < .05). Conclusion: The modified training program strengthens rehabilitation nurses' base management abilities; enhances their core competencies; expands their interest in and breadth, depth, and practicability of theoretical courses; and updates the teaching methods.

• Journal of Digital Convergence
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• v.18 no.9
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• pp.265-275
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• 2020

The burden of injury is widely considered to be very severe in our society. Nonetheless, we don't have enough data for injury surveillance. The objective of this research is to select and supplement CORE DATA for injury surveillance. For this purpose, this study had analyzed the literature such as the Quality Assessment Report about 'Causes of Death Statistics', 'Health Insurance Statistics' and 'Hospital Discharge Injury Surveillance' according to the six dimension of Statistics Quality. The analysis result is that 'Cause of Death Statistics' and 'Health Insurance Statistics' have the usefulness as the CORE DATA for injury surveillance. But there is a significant shortcoming in the Health Insurance Statistics, which is that there is a lack of the data about the external causes of injury. For supplementing the defect, this study proposes the system that the medical institutions should obligatorily report the external causes of injury when claim National Health Insurance Medical Care Expenses. As the results of this system, we can expect 'Establishing of Injury pyramid', 'Data Connecting with the National Pension' and 'Improving the Promptness of Injury Data'. And we expect the follow-up study for the realization of this system.

• Clean Technology
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• v.25 no.2
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• pp.161-167
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• 2019

Several types of reactors have been used during the past decade to perform fast pyrolysis of biomass. Among the developed fast pyrolysis reactors, fluidized bed reactors have been widely used in the fast pyrolysis process. In recent years, experimental studies have been conducted on the characteristics of biomass fast pyrolysis in a spouted bed reactor. The fluidization characteristics of a spouted bed reactor are influenced by particle properties, fluid jet velocity, and the structure of the core and annulus. The geometry of the spouted bed reactor is the main factor determining the structure of the core and annulus. Accordingly, to optimize the design of a spouted bed reactor, it is necessary to study the pyrolysis characteristics of biomass. However, no detailed investigations have been made of the fast pyrolysis characteristics of biomass in accordance with the geometry of the spouted bed reactor. In this study, fast pyrolysis experiments using Jatropha curcas L. seed shell cake were conducted in a conical spouted bed reactor to study the effects of reaction temperature and reactor cone angle on the product yield and pyrolysis oil quality. The highest energy yield of pyrolysis oil obtained was 63.9% with a reaction temperature of $450^{\circ}C$ and reactor cone angle of $44^{\circ}$. The results showed that the reaction temperature and reactor cone angle affected the quality of the pyrolysis oil.

• Journal of the Korea Society of Computer and Information
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• v.27 no.10
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• pp.267-274
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• 2022

The purpose of this study is to investigate the learning satisfaction and perception of the students who have taken the online classes of the Digital Innovation Sharing University in the field of new energy industry, and to analyze the relationship between the learning satisfaction and core competencies. In order to achieve this purpose, the results of the learning satisfaction survey of a total of 470 students who took the digital innovation sharing university classes in the new energy industry were analyzed in both quantitative and qualitative methods. As a result of quantitative analysis, students' learning satisfaction was generally above average, and they were particularly satisfied with the setting and operation of educational goals. In addition, it was found that students' learning satisfaction had a statistically significant effect on students' core competencies. As a result of the qualitative analysis, it was possible to confirm the direction of improvement of the curriculum in the areas of function, operation, and content. Based on the results of this study, it is expected that the digital innovation sharing university curriculum quality management feedback system will be prepared in the future, and it will be the foundation for the continuous establishment of the curriculum quality management system.

• Industry Promotion Research
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• v.2 no.2
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• pp.45-52
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• 2017

this study, the problem of the quality is analyzed by questionnaire analysis of the current quality managers, and the German meister system, the Japanese name deduction system, the functional manager, and the quality manager system. First, we set up a quality guide selection classification guide model. Secondly, we set up a model for combining experience and expertise with theory. Third, we set up a quality brand application model to enhance competitiveness of SMEs. Fourth, The basic model is presented. The expected effects of these models are that, in the knowledge-based economy, in terms of identifying, fostering, and utilizing superior talents, quality experts combine academic theories and experience in each field to provide core expertise and knowledge, As a transformative leader and expert, we will become a leader of innovation activities by enhancing corporate competitiveness, developing younger leaders, and cooperating with suppliers. In order to strengthen competitiveness of SMEs, It will be possible to scale and cultivate the technology of SMEs.

• Journal of Navigation and Port Research
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• v.26 no.2
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• pp.153-159
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• 2002

An empirical study was carried out to examine how Container Terminals in Busan view quality management activities by the provision of statistical evidence showing the efforts to enhance the standard of quality management, common factors of quality management activities and causal relationship among these factors. The data investigating the quality management for Busan Container Terminals were collected from 170 persons in charge of quality management for port services in Busan Container terminals by the use of questionnaire method and personal interviews. The Cronbach's a coefficient and factor analysis were used to analyze the reliability and the validity of measured variables. Furthermore, SEM (Structural Equation Modeling) method using AMOS(Analysis of MOment Structure) 4.0 was usea to analyze the cause-effect relationship among the source, activities and accomplishments of quality management representing the core concept of quality management system.

• Korean Medical Education Review
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• v.11 no.2
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• pp.15-24
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• 2009

Medical Students' competencies depend on the medical school curriculum. Basic medical education, in particular, is an important starting point for further medical competency development. We aimed to identify the most important areas of reform in the basic medical education curriculum of Yonsei Medical School. To accomplish this, we sought case studies of different medical schools and discussion points for quality improvement methods. A qualitative comparison method saturated through the systematic discussions on the emerging thematic approaches to determine the current directions in medical school curriculum reform. The discussions, which involved 7 experts, spanned 8 months and were based on a literature review, with focus on the 7 selected case studies. From the discussions, we concluded that in order to improve basic medical education curriculum, the following measures need to be carried out. First, an outcome-based curriculum is to be designed. The expected outcome is to be deliberately and succinctly defined and should be expressed as teaching and learning objectives. Second, the core subjects and elective subjects are to be classified on the basis of the aim, content, and passage level of the subjects. Hence, the core curriculum must be treated as a standard part of medical knowledge, and the elective curriculum must be richer and more in-depth. Third, universities should institutionalize regular evaluation of their departments. Appropriate and just evaluations should be made, and feedback given to the school's administrative department. Fourth, the departmental and administrative management of the basic medical education curriculum should be harmonized with each other. Finally, teaching and learning resources are to be increased and diversified and made available to professors and students for basic medical education.