• Title/Summary/Keyword: Convergent study

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Hypoglycemic and antioxidant effects of jaceosidin in streptozotocin-induced diabetic mice (Jaceosidin이 streptozotocin으로 유도된 당뇨 쥐의 혈당강하 및 항산화능에 미치는 영향)

  • Park, Eunkyo;Kwon, Byoung-Mog;Jung, In-Kyung;Kim, Jung-Hyun
    • Journal of Nutrition and Health
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    • v.47 no.5
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    • pp.313-320
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    • 2014
  • Purpose: In this study, we investigated the effects of jaceosidin on blood glucose regulation in type 1 diabetic mice. Methods: C57BL/6 mice were divided into four groups; normal control (Normal), diabetes control (D-Control), diabetes low-jaceosidin (D-0.005%), and diabetes high-jaceosidin (D-0.02%). Type 1 diabetes was induced by streptozotocin and mice were then fed a diet containing jaceosidin for eight weeks. Fasting blood glucose, oral glucose tolerance test, insulin tolerance test, lipid peroxidation, and antioxidant enzyme activities were assessed. Results: Jaceosidin supplementation for eight weeks had no effect on body weight, organ weight, and blood lipid profiles. However, jaceosidin supplementation significantly lowered fasting blood glucose level and reduced insulin resistance. We also found that jaceosidin supplementation increased antioxidant capacity by enhancement of catalase and GSH-px activities. Conclusion: These results suggest that jaceosidin could be a therapeutic candidate to ameliorate hyperglycemia through increase of antioxidant enzyme activity.

The Analysis of Student-student Verbal Interactions on the Problem-solving Inquiry Which was Developed for Creativity-increment of the Gifted Middle School Students (중학교 과학 영재의 과학 창의성 신장을 위한 문제 해결형 탐구 실험에서의 학생 간 대화 분석)

  • Kim, Ji-Young;Ha, Ji-Hee;Park, Kuk-Tae;Kang, Seong-Joo
    • Journal of Gifted/Talented Education
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    • v.18 no.1
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    • pp.1-21
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    • 2008
  • The purpose of this study was to develop problem-solving inquiries for the science gifted and to analyze the effects of problem-solving inquiries. The problem-solving inquiries were composed of scientific knowledge, scientific inquiry skills and creative thinking. The problem-solving inquiries were applied to the science gifted attending the institute of the gifted education. The test of science-creative problem solving (TSCPS) was used to know effects of improvement of science-creativity and the result of TSCPS showed the improvement of science creativity. The analysis of student-student dialogues during experiments showed that the type of dialogue was different on the type of problem-solving inquiry. The dialogue of convergent thinking was frequently showed up on the problem-solving inquiry needed logical thinking whereas that of divergent thinking on the problem-solving inquiry needed idea generation. The problem-solving inquiries had a positive effects on the improvement of the science-creativity.

Availability of the Time and Change Test in Screening for Dementia in the Elderly (노인에서 치매 조기선별을 위한 시각.금전계산 검사의 유용성)

  • Chung, Eun-Kyung;Shin, Min-Ho;Rhee, Jung-Ae
    • Journal of Preventive Medicine and Public Health
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    • v.36 no.2
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    • pp.101-107
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    • 2003
  • Objectives : Dementia has emerged as a leading public health problem in elderly persons, and its early detection is important for the treatment of curable cases, and in the educational support for other family members. Although dementia screening tests are available, they have not gained widespread use in community or primary care settings. Our goal was to validate the Tine and Change (T&C) Test, -including its validity and reliability in patients, and to assess it as a simple, standardized method for the screening of dementia in the rural elderly. Methods : The participants in this study comprised of 59 patients from an urban hospital and 405 persons from a rural community aged 65 years or older. The time test evaluated the understanding of clock hands indicating 11:10, and the change test the ability to make 1,000 Won from a group of coins, consisting of one 500, seven 100, and seven 50 Won coins. The T&C ratings were validated against a reference standard based on the physician's diagnosis of the patients. The convergent validity in relation to other cognitive measure, test-retest agreement, and inter-observer reliability were assessed. To assess the relationship between the Korean Mini-Mental State Exam (K-MMSE) and the T&C Test, the mean K-MMSE scores were compared with the results of the T&C Test in the elderly from a rural community. Results The T&C Test had a sensitivity and specificity of 73.0, and 90.9%, and positive and negative predictive values of 93.1, and 66.7%, respectively. The test-retest and inter-observer agreement rates were both 95%. The K-MMSE scores and T&C Test were significantly related in the elderly from a rural community (p<0.01), The T&C Test was not influenced by the educational status. The Time and Change Tests took a mean of 6.3 and 12.7 seconds, respectively, to complete Conclusion : The T&C Test is a simple, accurate and reliable, performance-based tool in the screening for dementia. Because it is quick, and easy-to-use, it is hoped the T&C Test will be used for the widespread cognitive screening of aging populations.

Construction and characterization of the bacteriophage P4 derivatives whose genome size suitable for packaging into a P2sir3-sized head (P2 sir3-sized head에 packaging 되기 용이한 크기의 박테리오파지 P4 유도체 조성과 정성 연구)

  • Kim, Kyoung-Jin
    • Korean Journal of Microbiology
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    • v.51 no.1
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    • pp.1-6
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    • 2015
  • The term "P2 sir-associated helper inefficiency" has been used to define the inefficient helper capability of P2 sir mutants for their satellite bacteriophage P4. The aim of this study was to investigate the factors overcoming P2 sir-associated helper inefficiency. At first, we verified whether the P2 cos region containing P4 sid71 cosP2 could overcome P2 sir-associated helper inefficiency with P2 sir3. The result was that P4 sid71 cosP2 could not overcome P2 sir-associated helper inefficiency with P2 sir3. Instead of cos region of P2, the size of the DNA packaged into a $P2_{sir}$-sized head seems to be important for overcoming P2 sir-associated helper inefficiency. In the present work, three kinds of P4 derivatives with packaged DNA sizes between those of P4 ost1 and P4 ost2, were constructed through DNA manipulation. In one P4 derivative, P4 sid71 delRI::apr, the size of the packaged DNA was identified with a CsCl buoyant equilibrium density gradient experiment. According to the burst sizes of the P4 derivatives, they could overcome P2 sir3-associated helper inefficiency. The size of the P4 derivative DNA suitable for packaging into a $P2_{sir3}$-sized head was 28-29 kb.

Research on Continuous After-Treatment Process and System for DTP(Digital Textile Printing) (DTP(Digital Textile Printing)용 후처리 및 연속공정 시스템에 관한 연구)

  • Park, Soon-Young;Jeon, Dong-Won;Park, Yoon-Cheol;Lee, Beom-Soo;Cho, Hang-Sung
    • Journal of Fashion Business
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    • v.15 no.5
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    • pp.43-54
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    • 2011
  • Digital Textile Printing(DTP) is appropriate for quick response system(QRS) and is closely connected with high value added fashion industry. Fashion products of high price are mainly silk and cotton. For high quality DTP products, it is important to optimize the parameters of media, pre and after-treatment, ink, printer, etc. DTP for these two fiber materials is also accompanied certainly with steaming as after-treatment process for coloration. Role of steam is like water in exhaustion dyeing. Steam can diffuse dye or ink in printing paste to fiber. Quality of DTP products depend on after-treatment processes such as steaming, washing, drying. Current production amount of DTP is smaller than one of conventional textile printing. However conventional after-treatment system has been using so far. This is mismatched with DTP in terms of process efficiency, spot work of small lot, quality control. In this study, continuous after-treatment system has been suitably designed for DTP that washing and drying are available after steaming. So, It is possible to improve efficiency of DTP process. Especially, the effects of after-treatment process, such as temperature of heat drum, steaming time on printability, color difference, color fastness were examined. Two types of samples(cotton knit and silk fabrics) were used. The results were obtained as follows : First, there is no a wide difference between the K/S values of cotton and silk treated with continuous after-treatment system and those of sample treated with conventional printing after-treatment method. So it is more effective to use the continuous after-treatment system than conventional printing after-treatment system in case of the daily throughput of 1,000 yards below. Second, after continuous after-treatment for DTP, K/S values were increased and lightness($L^*$) values were decreased. ${\Delta}E$ values were below 2.3. Third, DTP samples treated with continuous after-treatment system were tested for fastness(washing, light, rubbing). Grades of fastness(washing, light, rubbing) were above 3 grade.

The effects of S-STEAM program on creativity and multiple intelligences of young children (과학 중심 융합인재교육(S-STEAM) 프로그램이 유아의 창의성 및 다중지능에 미치는 영향)

  • Song, Min-Seo;Kim, Hyoung-Jai
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.4
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    • pp.361-372
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    • 2016
  • The purpose of this study was to develop a STEAM-based science education program for children and to verify its effectiveness. An S-STEAM-based science education program for young children was developed through careful analysis of prior research on science education for young children and S-STEAM. The participants were 29 four-year-old children from daycare centers located in Seoul (an experimental group of 14 and comparative group of 15). The S-STEAM program was applied to the experimental group, while the control group went through a general science education course provided by the government. TTCT of Creative Thinking (TTCT: Figures A and B) was used as a research tool, and a multiple intelligence test tool was applied to teachers of the groups. Afterwards, analysis of covariance was implemented to find the S-STEAM program's effects. First, the results showed positive effects on overall creativity, as well as in fluency, originality, abstractness, elaboration, and openness components of creativity. Second, the results showed positive effects on overall multiple intelligences and its components of linguistic, musical, spatial, logical/mathematical, physical exercise, interpersonal, and naturalist intelligence.

Labor market forecasts for Information and communication construction business (정보통신공사업 인력수급차 분석 및 전망)

  • Kwak, Jeong Ho;Kwun, Tae Hee;Oh, Dong-Suk;Kim, Jung-Woo
    • Journal of Internet Computing and Services
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    • v.16 no.2
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    • pp.99-107
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    • 2015
  • In this era of smart convergent environment wherein all industries are converged on ICT infrastructure and industries and cultures come together, the information and communication construction business is becoming more important. For the information and communication construction business to continue growing, it is very important to ensure that technical manpower is stably supplied. To date, however, there has been no theoretically methodical analysis of manpower supply and demand in the information and communications construction business. The need for the analysis of manpower supply and demand has become even more important after the government announced the road map for the development of construction business in December 2014 to seek measures to strengthen the human resources capacity based on the mid- to long-term manpower supply and demand analysis. As such, this study developed the manpower supply and demand forecast model for the information and communications construction business and presented the result of manpower supply and demand analysis. The analysis suggested that an overdemand situation would arise since the number of graduates of technical colleges decreased beginning 2007 because of fewer students entering technical colleges and due to the restructuring and reform of departments. In conclusion, it cited the need for the reeducation of existing manpower, continuous upgrading of professional development in the information and communications construction business, and provision of various policy incentives.

The Convergent Influence of Knowledge, Attitudes toward Caring for the Elderly and Geriatric Nursing Practice in Nursing Students (간호학생의 노인에 대한 지식, 노인돌봄태도가 노인간호실천에 미치는 융복합적 영향)

  • Kwon, Su-Hye;Kang, Hyo-Jeong;Youn, Soon-Chul;Kim, Young-Suk
    • Journal of Digital Convergence
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    • v.14 no.4
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    • pp.303-314
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    • 2016
  • The purpose of this study was to identify the relationships among knowledge, attitudes toward caring for the elderly and geriatric nursing practice and the influencing factors on geriatric nursing practice in nursing students. Data were collected from 255 nursing students with clinical practice experiences in three nursing schools in B city, with the measurement of Fact on Aging Quiz Part I, Attitudes toward Caring for the Elderly and Geriatric nursing practice. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and Stepwise multiple regression. Significant correlations were found among knowledge of, caring attitude towards the elderly and geriatric nursing practice. The significant factors influencing geriatric nursing practice were caring attitude towards the elderly, grade, and knowledge of the elderly, and these factors explained 27.4% of the variance. The findings suggest that effective educational strategies need to be developed and implemented to foster positive caring attitude towards and knowledge of the elderly in order to improve geriatric nursing practice in nursing students.

Distribution of Fish Assemblage and Stable Isotope Composition of Reeds according to Geomorphic Characteristics of Lagoons along the East Sea (동해안 석호의 지형학적인 특성에 따른 어류군집분포와 갈대의 안정동위원소비)

  • Lee, Jaeyong;Park, Seungchul;Kim, Minseob;Choi, Jae-Seok;Lee, Kwangyeol;Shin, Kyunghoon
    • Korean Journal of Ecology and Environment
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    • v.48 no.1
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    • pp.1-11
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    • 2015
  • Abstract The purpose of study is to identify the relationship between stable isotope composition of reed stems in coastal and understand the structure of the fish community in 10 lagoons along the East Sea. The fish species composition (particularly, anadromous fish species) and relative abundance of trophic guilds was influenced by difference of geomorphic characteristics among lagoons. Reed stems ${\delta}^{13}C$ and ${\delta}^{15}N$ values ranged from $-28.40{\pm}0.11$‰ to $-26.87{\pm}0.25$‰ and $-1.09{\pm}1.45$‰ to $12.08{\pm}0.53$‰, respectively. The differences in reed stem ${\delta}^{15}N$ values might be associated with anthropogenic landuse and the geomorphic characteristics among lagoons. These results provide useful information to improve the conservation of fish habitats (biodiversity), preserve lagoon habitats and contribute to watershed management effect against anthropogenic pollution from watershed in these lagoon ecosystems.

Validation of Pediatric Functional Assessment of Cancer Therapy Questionnaire (Version 2.0) in Brain Tumor Survivor Aged 13 Years and Older (Parent Form) (PedsFACT-BrS Parent of Adolescent)

  • Yoo, Hee-Jung;Kim, Dong-Seok;Lai, Jin-Shei;Cella, David;Shin, Hee-Young;Ra, Young-Shin
    • Journal of Korean Neurosurgical Society
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    • v.49 no.3
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    • pp.147-152
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    • 2011
  • Objective : The aim of this study was to evaluate the reliability and validity of the Pediatric Functional Assessment of Cancer Therapy Questionnaire Brain Tumor Survivor (version 2.0) Aged 13 years and older (Parent Form) (pedsFACT-BrS parent of adolescent). Methods : The pedsFACT-BrS parent of adolescent was translated and cross-culturally adapted into Korean, following standard Functional Assessment of Chronic Illness Therapy (FACIT) methodology. The psychometric properties of the pedsFACT-BrS parent of adolescent were evaluated in 170 brain tumor patient's mothers (mean age=43.38 years). Pretesting was performed in 30 mothers, and the results indicated good symptom coverage and overall comprehensibility. The participants also completed the Child Health Questionnaire Parent Form 50 (CHQ-PF-50), Neuroticism in Eysenck Personality Questionnaire, and Karnofsky score. Results : In validating the pedsFACT-BrS parent of adolescent, we found high internal consistency, with Cronbach's ${\alpha}$ coefficients ranging from 0.76 to 0.94. The assessment of test-retest reliability using intraclass correlation coefficient revealed satisfactory values with ICCs ranging from 0.84 to 0.93. The pedsFACT-BrS for parent of adolescent also demonstrated good convergent and divergent validities when correlated with the Child Health Questionnaire Parent Form 50 (CHQ-PF-50) and the Neuroticism in Eysenck Personality Questionnaire. The pedsFACT-BrS parent of adolescent showed good clinical validity, and effectively differentiated between clinically distinct patient groups according to the type of treatment, tumor location, shunt, and Karnofsky score of parent proxy report. Conclusion : We confirmed that this reliable and valid instrument can be used to properly evaluate the quality of life of Korean adolescent brain tumor patients by their parents' proxy report.