• 대한지역사회영양학회지
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• 제28권4호
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• pp.317-328
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• 2023

Objectives: This study aimed to investigate the correlation between adolescents' dietary safety management competency, value recognition, efficacy, and competency of convergence using the dietary area (CUDA). Methods: Data were collected from 480 middle and high school students in Daegu, Gyeongbuk and Seoul, Gyeonggi using a self-administered five-point Likert scale questionnaire from May to July 2021. A questionnaire was used to investigate dietary safety management competency, awareness of convergence, recognition of the benefits, efficacy, and competency of CUDA. Results: We conducted factor, reliability, correlation, and regression analyses using SPSS 25. The average scores for each factor were: dietary significance (3.68); dietary safety management knowledge (3.34); food selection and cooking (3.72); nutrition management (3.38); weight management (3.28); risk dietary management (3.13); CUDA interest (2.98); convergence necessity (3.50); benefits in specialized areas (3.31); benefits in everyday life (3.48); efficacy of science and technology convergence (3.35); convergence efficacy with humanities, social science, and arts (3.31); and CUDA competency (3.41). The score for interest in CUDA was lower than that for the recognition of CUDA benefits. Significant positive correlations were observed between all factors except between risk dietary management and both nutrition and weight management (P < 0.01). Interest in CUDA and recognition of the need for convergence exhibited a positive and significant effect on all factors of the perception of CUDA benefits and efficacy. The subgroup factors of dietary safety management competency and the recognition of CUDA had a positive effect on the CUDA competency (P < 0.001, R²= 0.58). Conclusions: Strengthening dietary safety management competency and increasing the awareness of CUDA can enhance adolescents' convergence competency. Therefore, CUDA and targeted education must be actively promoted among adolescents.

• 한국미생물·생명공학회지
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• 제50권4호
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• pp.533-547
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• 2022

This study investigated the hair growth effect of Schisandra chinensis extract (TS-SC) and TS-SC fermented by Lactobacillus plantarum (TS-SCLF) on human dermal papilla cells (hDPCs). The production of vascular endothelial growth factor (VEGF), insulin-like growth factor 1 (IGF-1), keratinocyte growth factor/fibroblast growth factor 7 (KGF/FGF-7) and hepatocyte growth factor (HGF), transforming growth factor beta 1 (TGF-β1) were examined. The secretion rates of VEGF and KGF/FGF-7 were high in TS-SC, and the secretion rates of IGF-1 and HGF were high in TS-SCLF. TGF-β1 was inhibited in a concentration-dependent manner in all samples. Gene expression of VEGF, IGF-1, KGF, HGF and alkaline phosphatase, relevant to hair growth, were examined. The data revealed that TS-SC and TS-SCLF successfully promoted hair growth in hDPCs. The IGF-1 gene was expressed in a dose-dependent manner in TS-SCLF. These results indicate that TS-SC and TS-SCLF fermented extract effectively promoted hair growth and gene expression relevant to hair growth in hDPCs. Used in clinical trials the test substance 'CMK-LPF01' showed a statistically significant increase in the number of hairs at 8 weeks, 16 weeks, and 24 weeks compared to before product use, and a change in hair growth, a secondary efficacy evaluation variable. Through additional research in the future, it is expected that "CMK-LPF01" can be developed as a functional material that can help alleviate symptoms of hair loss.

• 한국인터넷방송통신학회논문지
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• 제10권4호
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• pp.137-143
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• 2010

본 논문은 채널에서 발생되는 진폭과 위상 찌그러짐을 보상하기위한 MCMA (Modified Constant Modulus Algorithm)의 비용 함수에서 weighting factor에 의한 자기 적응 등화의 성능을 비교한 것이다. MCMA 는 기존 방식인 CMA 의 비용 함수를 개선하여 등화기의 출력에서 진폭과 위상에 대한 오차 함수를 최소화할 수 있으며, 이때 weighting factor 의 값이 이용된다. 등화기의 성능을 비교할 때 initial state와 steady state로 분류하고 미리 정해진 레벨까지의 수렴 시간과 수렴 속도 및 안정된 등화 상태를 나타내며, 이들은 weighting factor에 의해 결정된다. 컴퓨터 시뮬레이션을 통하여 weighting factor에 따라 이들 2 가지 state 에 대한 각각 상이한 결과를 확인할 수 있었다. 본 결과를 이용하여 사용되는 통신 채널의 환경에 따라 weighting factor 값을 적절히 선택한다면 고품질의 디지털 정보 전송이 가능하게 될 것으로 기대된다.

• Journal of Ginseng Research
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• 제44권6호
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• pp.790-798
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• 2020

Background: Beneficial effects of Korean Red Ginseng (KRG) on polycystic ovarian syndrome (PCOS) remains unclear. Methods: We examined whether pretreatment (daily from 2 hours before PCOS induction) with KRG extract in water (KRGE; 75 and 150 mg/kg/day, p.o.) could exert a favorable effect in a dehydroepian-drosterone (DHEA)-induced PCOS rat model. Results: Pretreatment with KRGE significantly inhibited the elevation of body and ovary weights, the increase in number and size of ovarian cysts, and the elevation of serum testosterone and estradiol levels induced by DHEA. Pretreatment with KRGE also inhibited macrophage infiltration and enhanced mRNA expression levels of chemokines [interleukin (IL)-8, monocyte chemoattractant protein-1), proinflammatory cytokines (IL-1β, IL-6), and inducible nitric oxide synthase in ovaries induced by DHEA. It also prevented the reduction in mRNA expression of growth factors (epidermal growth factor, transforming growth factor-beta (EGF, TGF-β)) related to inhibition of the nuclear factor kappa-light-chain-enhancer of activated B cell pathway and stimulation of the nuclear factor erythroid-derived 2-related factor 2 pathway. Interestingly, KRGE or representative ginsenosides (Rb1, Rg1, and Rg3(s)) inhibited the activity of inflammatory enzymes cyclooxygenase-2 and iNOS, cytosolic p-IκB, and nuclear p-nuclear factor kappa-light-chain-enhancer of activated B in lipopolysaccharide-induced RAW264.7 cells, whereas they increased nuclear factor erythroid-derived 2-related factor 2 nuclear translocation. Conclusion: These results provide that KRGE could prevent DHEA-induced PCOS via antiinflammatory and antioxidant activities. Thus, KRGE may be used in preventive and therapeutic strategies for PCOS-like symptoms.

• 한국산학기술학회논문지
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• 제19권2호
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• pp.228-237
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• 2018

본 연구는 선행연구로부터 지역창조화 요인을 측정할 수 있는 지표를 개발하고, 우리나라 15개 시 도의 2008년부터 2012년까지 5년간의 지역창조화 균형패널자료를 구축하여 패널회귀분석법을 통해 지역창조화와 지역성장과의 관계를 실증분석하였다. 분석결과 첫째, 지역창조화 요인 중 기초자산 부문의 창조인력과 무형자산 영역, 경제주체 부문의 창조기업 영역, 지역공간 부문의 창조적 지역환경 영역, 핵심산업 부문의 융합산업과 창조산업은 GRDP(Gross Regional Domestic Product, 지역내총생산)와 의미있는 정(+)의 영향관계가 나타났다. 반면, 조직화 부문은 하위영역 모두 통계적으로 GRDP와 유의미한 영향관계를 확인할 수 없었다. 둘째, 지역창조화 요인 중 기초자산 부문의 창조인력과 조직화 부문의 창업과 기업가 정신 영역, 경제주체 부문의 창조기업 영역, 지역공간 부문, 핵심산업 부문의 융합산업 영역은 고용율과 의미있는 정(+)의 영향관계가 나타났다. 반면, 기초자산 부문의 유형 무형 창조자산 영역, 조직화 부문의 융합경영과 융합행정, 경제주체 부문의 대 중견 중소기업과 중앙정부 및 지자체 영역, 핵심산업 부문의 창조산업 영역은 고용율과 유의미한 영향관계를 확인할 수 없었다. 본 연구의 결과는 지역창조화를 위한 현황을 진단하고, 추진과정과 장단기성과를 점검하는데 시사점을 제공할 것이다. 또한, 중앙정부의 지방자치와 분권강화 정책을 견인할 수 있는 기초수단이 될 것이다.

• 한국음향학회지
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• 제13권4호
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• pp.77-85
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• 1994

본 연구에서는 필터의 차수가 적절한 수준으로 자동적으로 조정되는, 최적 수렴 인자를 갖는 최대 경사 (steepest descent) 방식의 적응 알고리듬을 제안한다. 지금까지 적응 신호 처리의 여러 응용 분야에 적응 필터를 사용할 때, 사전 지식이나 경험에 비추어 필터 차수를 고정하여 이용하여 왔다. 하지만 실제 실행시 필요한 필터 차수를 알기는 어렵고 되도록 큰 차수의 필터를 실행해야만 한다. 이로 인하여 필터 차수가 너무 큰 경우 필요없는 계산량이 증가하게 된다. 제안한 가변 길이 최적 수렴 인자 알고리듬은 주어진 차수 한도 내에서 자동적으로 적절한 절터 차수를 찾아 동작하므로, 불필요한 계산량의 증가를 줄여서 결과적으로 수렴 속도의 향상과 정상 상태에서의 수렴 오차를 줄일 수 있다. 제안한 알고리듬의 타당성은 시스템 식별에 대한 컴퓨터 모의 실험으로 입증하였다.

• 한국융합학회논문지
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• 제1권1호
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• pp.49-55
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• 2010

정보통신기술 발전에 따라 많은 장치들간의 통신과 네트워킹의 수용이 이뤄지고 있다. 장치간의 통신을 위한 융합 사업이 빠르게 발전되어지고 있다. IT 융합 통신은 무선통신에서 차후 개척분야의 하나로 여겨지고 있다. 본 논문에서는 IT 융합 구조에서 M2M, 지능형 자동차, 스마트그리드, U-헬스케어에 대한 보안 위협요소를 분석하였다. 임베디드 시스템 보안, 포렌식 보안, 사용자 인증과 키관리 기법에 대한 IT 융합 보안의 방향을 제안하였다.

• 대한전기학회논문지
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• 제41권9호
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• pp.1021-1030
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• 1992

When using a least squares estimator with exponential forgetting factor to identify continuous-time deterministic system, the problem of determining minimum eigenvalue is described in this paper. It is well known fact that the convergence rate of parameter estimates relies on various factors consisting of the estimator and especially, theirproperties can be directly affected by all eigenvalues in the parameter error differential equation. Fortunately, there exists only one adjusting eigenvalue in the given estimator and then, the parameter convergence rates depend on this minimum eigenvalue. In this note, a new result to determine the minimum eigenvalue is proposed. Under the assumption that the input has as many spectral lines as the number of parameter estimates, it can be proven that the minimum eigenvalue converges to a constant value, which is a function of the forgetting factor and the parameter estimates number.

• Geomechanics and Engineering
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• 제14권4호
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• pp.325-336
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• 2018

Deformation of rock masses is not only related to rock itself, but also related to discontinuities, the latter maybe greater. Study on crack propagation at discontinuities is important to reveal the damage law of rock masses. DDARF is a discontinuous deformation analysis method for rock failure and some modified algorithms are proposed in this study. Firstly, coupled modeling methods of AutoCAD-DDARF and ANSYS-DDARF are introduced, which could improve the modeling efficiency of DDARF compared to its original program. Secondly, a convergence criterion for automatically judging the computation equilibrium is established, it could overcome subjective drawbacks of ending one calculation by time steps. Lastly but not the least, relationship between the super relaxation factor and the calculation convergence is analyzed, and reasonable value range of the super relaxation factor is obtained. Based on these above modified programs, influences on crack propagation of joint angle, joint parameters and geo-stresses' side pressure are studied.

• BMB Reports
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• 제48권9호
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• pp.525-530
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• 2015

Activation of the Wnt/β-catenin pathway plays a pathogenic role in age-related macular degeneration (AMD) and is thus a potential target for the development of therapeutics for this disease. Here, we demonstrated that Wnt5a antagonized β-catenin response transcription (CRT) induced with Wnt3a by promoting β-catenin phosphorylation at Ser33/Ser37/Thr41 and its subsequent degradation in human retinal pigment epithelial (RPE) cells. Wnt5a decreased the levels of vascular endothelial growth factor (VEGF), tumor necrosis factor-α(TNF-α), and nuclear factor-κB (NF-κB), which was up-regulated by Wnt3a. Furthermore, Wnt5a increased E-cadherin expression and decreased cell migration by down-regulating Snail expression, thereby abrogating the Wnt3a-induced epithelial-mesenchymal transition (EMT) in human RPE cells. Our findings suggest that Wnt5a suppresses the pathogenic effects of canonical Wnt signaling in human RPE cells by promoting β-catenin phosphorylation and degradation. Therefore, Wnt5a has significant therapeutic potential for the treatment of AMD. [BMB Reports 2015; 48(9): 525-530]