• Biomolecules & Therapeutics
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• v.27 no.1
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• pp.1-14
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• 2019

Resveratrol was first isolated in 1939 by Takaoka from Veratrum grandiflorum O. Loes. Following this discovery, sporadic descriptive reports appeared in the literature. However, spurred by our seminal paper published nearly 60 years later, resveratrol became a household word and the subject of extensive investigation. Now, in addition to appearing in over 20,000 research papers, resveratrol has inspired monographs, conferences, symposia, patents, chemical derivatives, etc. In addition, dietary supplements are marketed under various tradenames. Once resveratrol was brought to the limelight, early research tended to focus on pharmacological activities related to the cardiovascular system, inflammation, and cancer but, over the years, the horizon greatly expanded. Around 130 human clinical trials have been (or are being) conducted with varying results. This may be due to factors such as disparate doses (ca. 5 to 5,000 mg/day) and variable experimental settings. Further, molecular targets are numerous and a dominant mechanism is elusive or nonexistent. In this context, the compound is overtly promiscuous. Nonetheless, since the safety profile is pristine, and use as a dietary supplement is prevalent, these features are not viewed as detrimental. Given the ongoing history of resveratrol, it is reasonable to advocate for additional development and further clinical investigation. Topical preparations seem especially promising, as do conditions that can respond to anti-inflammatory action and/or direct exposure, such as colon cancer prevention. Although the ultimate fate of resveratrol remains an open question, thus far, the compound has inspired innovative scientific concepts and enhanced public awareness of preventative health care.

• Journal of the Korea Institute of Military Science and Technology
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• v.21 no.6
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• pp.886-893
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• 2018

U.S. and the allies attacked chemical weapons sites in Syria in 2018, and verbal battles are carried out about the effectiveness of the air strike. Syria claimed 13 missiles were shot down, and Russia claimed 71 missiles were shot down while the U.S. released pictures of completely destroyed targets, only. It led controversy about the effectiveness of missile defense system. If there is a method to observe mission success rate of the air strike, it can not only improve combat awareness but also can be a good sales strategy in military industry. This paper describes effects and considerations of a Weapon Data Link(WDL) technology which can be used as a smoking gun of effectiveness. The paper describes WDL abilities such as In-Flight Track Update, Loiter, and Bomb Hit Indication etc., and presents examples of expected effectiveness of the WDL. In addition, this paper briefly summarizes operational consideration for better performance.

• International Journal of Advanced Culture Technology
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• v.6 no.4
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• pp.12-19
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• 2018

This article aims to discuss the transition of the Kazakh writing system from Cyrillic to Latin. First, the study investigates the relationship between the Kazakh Cyrillic alphabet and phonology, in order to linguistically evaluate the efficiency of the writing system. Second, the process of determining the Kazakh Latin alphabet is discussed in terms of the Kazakh phonological system. Third, the factors that determined the Latin alphabet of Kazakh language are analyzed. In Kazakh, the phonemic system is subject to controversy among linguists, but it can be said that the phonological system basically follows the one-to-one correspondence to the Russian and Kazakh phonemes. As for the depth of orthographies, Kazakh Cyrillic writing system is not based on the shallow orthographies, so it incorporates morphophonemic information to make skilled readers understand easier. The political and social aspects are considered as a cause of the alphabet change. Although there are studies suggesting the conversion of the writing system is caused by the extrinsic factors rather than the intrinsic factors, the five criteria of Smalley (1964), which compromise the intrinsic and extrinsic factors, are also persuasive. The five factors are 1) Maximum motivation for the learner, 2) Maximum representation of speech, 3) Maximum ease of learning, 4) Maximum transfer, 5) Maximum ease of reproduction.

• Environmental Engineering Research
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• v.24 no.3
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• pp.382-388
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• 2019

Although nanobubbles attract significant attention, their characteristics and applications have not been thoroughly defined. There are diverse opinions about the definition of nanobubbles and controversy regarding methods that verify their characteristics. This study defines nanobubbles as having a size less than $1{\mu}m$. The generation of these sub-micron (nano) bubbles may be verified by induced coalescence or light scattering. The size of a sub-micron (nano) bubbles may be measured by optical, and confocal laser scanning microscopy. Also, the size may be estimated by the relationship of bubble size with the dissolved oxygen concentration. However, further research is required to accurately define the average bubble size. The zeta potential of sub-micron (nano) bubbles decreases as pH increases, and this trend is consistent for micron bubbles. When the bubble size is reduced to about 700-900 nm, they become stationary in water and lose buoyancy. This characteristic means that measuring the concentration of sub-micron (nano) bubbles by volume may be possible by irradiating them with ultrasonic waves, causing them to merge into micron bubbles. As mass transfer is a function of surface area and rising velocity, this strongly indicates that the application of sub-micron (nano) bubbles may significantly increase mass transfer rates in advanced oxidation and aeration processes.

• Journal of the Korean Society of Food Culture
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• v.34 no.1
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• pp.1-13
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• 2019

This study was conducted to track the appearance of Aguijjim and its popularity on the national level. Furthermore, changes in the monkfish recipe and how they impacted the consumption of monkfish were investigated. It is assumed that monkfish was consumed by Japanese in Korea during the Japanese colonial era. After liberation, people cooked the fish as soup. In the 1960s, Aguijjim was invented in Masan. There is great controversy regarding how the dish was born. It has been asserted that it was created by one specific person, that refugees with insufficient food developed, and that it is just an advancement of Bugeojjim. Aguijjim restaurants began to appear in Seoul in the 1970s, and in the 1990s streets full of Aguijjim restaurants formed. Moreover, popular music and literature referenced Aguijjim in the late 1990s. As Aguijjim has developed and the formation of Aguijjim street have combined, the consumption of monkfish has increased drastically, leading to its import. As cooking methods have transformed, the fish with the unpleasant look which was thrown out in the past, have dramatically gained public interest. 'Masan Aguijjim' became an independent brand that represents a local food that has also been nationalized in a short amount of time.

• The Korean Journal of Food And Nutrition
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• v.32 no.3
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• pp.202-207
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• 2019

The objective of this study was to analyze labeling improvements and evaluate willingness to pay for health functional foods with a focus on the caution for intake. For this study, we conducted a survey on health functional food intake behavior, confirmation and improvements of cautions for intake. We assessed the willingness to pay for improvement of the caution for intake. Consumers anticipate improved immune function, and fatigue improvement after consumption of health functional foods. They mainly checked the function components related to efficacy and effectiveness, ingredients and their contents, ingestion amount and method, expiry date and best mode of storage, product name, and cautions associated with ingestion of health functional foods. They has been difficulties in obtaining sufficient caution information for intake from the current labeling method. Therefore, it is necessary to improve the labeling of caution for intake. The analysis indicated that about 5.14% of the respondents were willing to pay more if new labeling was introduces. However, there is still controversy over their safety, which is damaging to the consumers. Therefore, by providing consumers with accurate and detailed information on cautions for intake, it can contribute to securing safety and improving the quality of health functional foods.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.3
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• pp.1119-1139
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• 2021

Among the scientific literature, it has not been possible to find a consensus on the definition of the limits or properties that allow differentiating or grouping the cyber-physical systems (CPS) and the Internet of Things (IoT). Despite this controversy the papers reviewed agree that both have become crucial elements not only for industry but also for society in general. The impact of a malware attack affecting one of these systems may suppose a risk for the industrial processes involved and perhaps also for society in general if the system affected is a critical infrastructure. This article reviews the state of the art of the application of machine learning in the automation of malware detection in cyberphysical systems, evaluating the most representative articles in this field and summarizing the results obtained, the most common malware attacks in this type of systems, the most promising algorithms for malware detection in cyberphysical systems and the future lines of research in this field with the greatest potential for the coming years.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.1
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• pp.15-22
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• 2018

Raymond, who adopted Le Corbusier's Errazuris House Project, built Karuizawa Villa by incorporating Japan's aspiration for Western modern architecture and strong convictions regarding the preservation of traditional culture heritage, which were prevalent in Japan at the time. Despite the controversy over his plagiarism, Karuizawa Villa shows several unique architectural characteristics. First, in terms of the arrangement and access system, the villa has a common space that affords a view of the lake by accessing from the mountain side. Second, in terms of spatial composition, the common space is connected to the mesonnette by placing a trail to enable enjoyment of natural scenery. In particular, personal space is planned in the shape of a cross by connecting several surfaces to the outside in order to secure enjoyment of the natural environment. Lastly, in the aspect of structure and materials, both architectural buildings adopted masonry by using natural stone as well as building materials suitable for each region and climate by using logs in constructing the main columns and beams. Through Karuizawa Villa, Raymond is considered to have established his own style by combining the standard of Western modern architecture and the elements of Japanese traditional architecture while valuing local architectural technology.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.4
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• pp.625-633
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• 2021

Bangladesh's growing foreign aid has sparked controversy over whether it affects the country's economic performance. This review assesses foreign aid's influence on the country's economic growth with annual data covering the 1989-2018 period. The Autoregressive Distributed Lag (ARDL) model is applied to achieve the research objective, and the empirical results indicate a substantial and robust impact of foreign assistance on economic growth. The outcome further reveal that domestic investment also contributes significantly to the country's economic evolution. However, trade openness plays a substantial positive role in the short run, although the impact is immaterial in the long run. The empirical findings indicate that the association between aid, domestic investment, and growth has a confident meaningful effect at 1 per cent level in the long run, whereas aid influences more than domestic investment. However, in the short run, aid, domestic investment, trade openness, and growth show positive and noteworthy response also at 1 percent level. This review undertakes a detailed analysis about the country's economic growth, and grounded on its outcome, this work suggests that focus should be placed more on creating domestic investment, promoting more export, and allocation of aid should be determined by the relative needs of the country.

• Journal of Contemporary Eastern Asia
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• v.19 no.2
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• pp.125-147
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• 2020

On the World Refugee Day in 2017, Yao Chen, a Chinese actress, philanthropist, and social media influencer, posted messages in her Weibo in support of the United Nations Refugee Agency (UNHCR). Yet, social media users quickly interpreted this supportive message of the refugee program as encouraging people to "accept and receive refugees" (jieshou nanmin) into China. Particularly, the category of Middle Eastern refugees elicited most criticism in China's cyberspace. As the inclusion of refugees is an integral part of immigrant multiculturalism, this article examines the limits of multicultural imagination of refugees―particularly those from the Middle Eastern and North Africa―in contemporary China. I argue that the limits of multicultural imagination in contemporary China is profoundly shaped by an intricate interweaving of domestic policies and global imaginaries toward refugees. By deploying a mixed methodology, such limits are examined from legal-institutional, ideological, and sociocultural perspectives. More specifically, three interrelated aspects will be highlighted in the article: (1) the global circulation of right-wing populism imaginaries, and their entanglements with the anti-Muslim sentiments in contemporary China; (2) the current insufficiency of the legal-institutional framework regarding refugees and asylum-seekers, which needs to be contextualized in China's modern history of dealing with refugee issues; (3) population politics, the rise of Han-centric nationalism, and their constraining impact on the interpretation of historical events related to cultural diversity. In conclusion, this article also offers potential implications for further examining the different yet potentially intersected genealogies of multicultural imaginaries beyond the Middle Eastern and North African refugees in Asia.