• 제목/요약/키워드: Control experiment

검색결과 11,191건 처리시간 0.037초

사향이 CCl4로 유발된 mouse의 간 손상에 미치는 영향 (Protective Effects of Moschus Against Carbon Tetrachloride-Induced Acute Hepatotoxicity in ICR Mice)

  • 박재석;김성욱;이규재;권기록
    • 대한약침학회지
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    • 제9권1호
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    • pp.45-52
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    • 2006
  • Objectives : This study was aimed at investigating liver protection mechanism of Moschus by inducing liver toxicity through $CCl_4$ in mice and evaluated histological and serological findings. Methods : Experiment groups was categorized into untreated normal group, $CCl_4$ treated control group, and orally administered Moschus experiment group. At the termination of experiment, gross examination of the liver as well as histological findings, and Total protein, Total bilirubin, Direct bilirubin SGOT, SGPT, and ALP contents in the serum were evaluated. Results : 1. For gross examination and histological findings, $CCl_4$ treated control group showed destroyed lobular structure, increased fibrosis, as well as hepatic cirrhosis. For the group treated with Moschus, the lobular structure suffered less damage, and showed lower level of fibrosis and liver cirrhosis compared to the control group. 2. For serum analysis, Total protein were significantly increased in the Moschus experiment group than the control group. 3. Total bilirubin didn't show significant differences between the two groups. but direct bilirubin was significantly increased in the Moschus experiment group than the control group. 4. SGOT, SGPT, were significantly decreased in the normal and Moschus experiment groups compared to the control group. 5. ALP was significantly decreased in the normal group compared to the control group, but Moschus experiment group didn't show significant differences compared to the control group. Conclusion : Taken together, Moschus can be effectively used for recovering the liver functions and further researches must be conducted to verify the efficacies of Moschus bile juice.

모바일-매니퓰레이터 구조 로봇시스템의 안정한 모션제어에 관한연구 (A Study on Stable Motion Control of Mobile-Manipulators Robot System)

  • 박문열;황원준;박인만;강언욱
    • 한국산업융합학회 논문집
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    • 제17권4호
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    • pp.217-226
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    • 2014
  • Since the world has changed to a society of 21st century high-tech industries, the modern people have become reluctant to work in a difficult and dirty environment. Therefore, unmanned technologies through robots are being demanded. Now days, effects such as voice, control, obstacle avoidance are being suggested, and especially, voice recognition technique that enables convenient interaction between human and machines is very important. In this study, in order to conduct study on the stable motion control of the robot system that has mobile-manipulator structure and is voice command-based, kinetic interpretation and dynamic modeling of two-armed manipulator and three-wheel mobile robot were conducted. In addition, autonomous driving of three-wheel mobile robot and motion control system of two-armed manipulator were designed, and combined robot control through voice command was conducted. For the performance experiment method, driving control and simulation mock experiment of manipulator that has two-armed structure was conducted, and for experiment of combined robot motion control which is voice command-based, through driving control, motion control of two-armed manipulator, and combined control based on voice command, experiment on stable motion control of voice command-based robot system that has mobile-manipulator structure was verified.

체력진단 평가를 통한 뇌성마비 아동과 정상아동의 운동능력 비교연구 (Comparison of Motor Fitness of Cerebral Palsy Chidren with normal throug Phyisical Fitness Diagnosis Evaluation)

  • 이강준;박래준;김종열
    • The Journal of Korean Physical Therapy
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    • 제12권1호
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    • pp.101-112
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    • 2000
  • The aim of this study is to compared the cerebral palsy children with normal children in the exercise and cardio vascular ability after this study as the fundamental data fer mating programs for the cerebral palsy children. The test of this study is about twenty girls, the control group of the normal children(n=10) and the experiment group of cerebral palsy children(n=10). They were studied in four aspects which were the anthropometry, the medical check in the rest, the physical fitness or exercise roads test and the change of the target heart rate during exercise. The result were as follows : 1. The characteristic of the physical type : The control group is higher than the experiment group in the standing height and the body weight but their's little difference between them (p<0.05). The control group is lower than the experiment group in the body fat. 2. The characteristic of the medical check in the rest : The control group is higher than the experiment group in the vital capacity and flood expiratoryvolume one second. The control group is higher that the experiment group in the blood pressure of systolic and Diastolic. There's little difference between them(p<0.01). The control is lower than the experiment group in the heart pulse rate. There's little difference between them(p<0.005). 3. The characteristic of basic physical strength evaluation : The experiment group is the lowest dynamic muscular endurance, balance, agility and endurance which need to move the body with weight. The control group is much higher than the experiment group in the flexibility and muscle strength(Back strength). There's no difference between them(p<0.05). 4. The characteristics of the exercise stress last : The control group is higher than the experiment group in the endurance, the maximum of oxygen intake, endurance level and the out take of calory. There's little difference between them(p<0.01). 5. The characteristic of the change of the target heart rate during exercise : The control group is lower than the experiment group exchange of target heart rate, There's no difference them.

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Intra-Spinal Bone Marrow Mononuclear Cells Transplantation Inhibits the Expression of Nuclear Factor-${\kappa}B$ in Acute Transection Spinal Cord Injury in Rats

  • Shrestha, Rajiv Prasad;Qiao, Jian Min;Shen, Fu Guo;Bista, Krishna Bahadur;Zhao, Zhong Nan;Yang, Jianhua
    • Journal of Korean Neurosurgical Society
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    • 제56권5호
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    • pp.375-382
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    • 2014
  • Objective : To assess the effect of bone marrow mononuclear cells (BMMNCs) transplantation in the expression of nuclear factor-${\kappa}B$ (NF-${\kappa}B$) in spinal cord injury (SCI) in rats. Methods : BMMNCs were isolated from tibia and femur by a density gradient centrifugation. After establishment of acute transection SCI, rats were divided into experiment (BMMNCs), experiment control (0.1 M PBS infused) and sham surgery groups (laminectomy without any SCI). Locomotor function was assessed weekly for 5 weeks post-injury using BBB locomotor score and urinary bladder function daily for 4 weeks post-injury. Activity of NF-${\kappa}B$ in spinal cord was assessed by immunohistochemistry and reverse transcriptase polymerase chain reaction. Results : At each time point post-injury, sham surgery group had significantly higher Basso, Beattie, Bresnahan locomotor and urinary bladder function scores than experiment and experiment control group (p<0.05). At subsequent time interval there were gradual improvement in both experiment and experiment control group, but experiment group had higher score in comparison to experiment control group (p<0.05). Comparisons were also made for expression of activated NF-${\kappa}B$ positive cells and level of NF-${\kappa}B$ messenger RNA in spinal cord at various time points between the groups. Activated NF-${\kappa}B$ immunoreactivity and level of NF-${\kappa}B$ mRNA expression were significantly higher in control group in comparison to experiment and sham surgery group (p<0.05). Conclusion : BMMNCs transplantation attenuates the expression of NF-${\kappa}B$ in injured spinal cord tissue and thus helps in recovery of neurological function in rat models with SCI.

체중현수 트래드밀 훈련이 뇌졸중노인의 보행과 근활성에 미치는 영향 (The Efficacy of Treadmill Training with Body Weight Support on Ambulation and Muscle Activity with Elderly Chronic Stroke)

  • 김성학
    • 대한물리치료과학회지
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    • 제11권2호
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    • pp.27-37
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    • 2004
  • The propose of the study was to evaluate the efficacy of the partial body weight support during treadmill training on the ambulation in elderly with chronic stroke. Fourteen hemiplegic volunteers participated and were divided into an experimental and control groups. In the experimental group, the body weight support during treadmill training was performed 3 times per week for 6 weeks. In the control group, usual treadmill training was applied. Before and after experiments, temporal-spatial gait parameters were measured. The date of 14 patients who carried out the whole experimental course were statistically analyzed. The results of the study were : 1. In the comparison of gait velocity before and after experiment, the gait velocity was significantly increased in the experimental group and the control group(p<.05). In the comparison of difference of the gait velocity between groups, there was not significant difference between the experimental group and the control group(p>.05). 2. In comparison of gait cadence before and after experiment, the gait cadence was significantly increased in both groups(p<.05). In the comparison of difference of the gait cadence between groups, there was not significant difference between the experimental group and the control group(p>.05). 3. In the comparison of step length before and after experiment, the step length was significantly increased in the experimental group and the control group(p<.05). In the comparison of difference of the step length between groups, there was not significant difference between the experimental group and the control group(p>.05). 4. In the comparison of vastus medialis root mean square(RMS) before and after experiment, the vastus medialis RMS was significantly increased in the experimental group(p<.05). In the comparison of vastus medialis root mean square(RMS) before and after experiment, the vastus medialis RMS was not significantly increased in the experimental group(p>.05). In the comparison of difference of the vastus medialis RMS between groups, there was not significant difference between the experimental group and the control group(p>.05). 5. In the comparison of latency of somatosensory evoke potential(SSEP) before and after experiment, the latency of SSEP was significantly increased in the experimental group(p<.05). In the comparison of latency of somatosensory evoke potential(SSEP) before and after experiment, the latency of SSEP was significantly decreased in the control group(p>.05). In the comparison of difference of the latency of SSEP between groups, there was not significant difference between the experimental group and the control group(p>.05). 6. In the comparison of functional ambulation profile(FAP) before and after experiment, the FAP was not significant difference in the experimental group and the control group(p>.05). In the comparison of difference of the FAP between groups, there was not significant difference between the experimental group and the control group(p>.05).

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