• 항공우주시스템공학회지
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• 제10권2호
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• pp.7-13
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• 2016

Multi disciplinary approach for aerodynamics, structure, propulsion, and flight control system is necessary to develop High Altitude Long Endurance Unmanned Aerial Vehicles (HALE UAV). Various HALE UAV development trends are surveyed to understand their operational requirements. Separating the UAV Take Off Weight by 150kg, Airworthiness implementation direction for HALE UAV is studied under the current Airworthiness regulations. NATO STANAG 4671 and STANAG 4703 Airworthiness certification criteria are analyzed, and their applicability was proposed for future HALE UAV development. In addition, minimization of the risk for UAV is studied by considering probability of cumulative catastrophic failure for HALE UAV. This Hazard Risk Index can support the future UAV Airworthiness Certification Criteria.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 하계학술발표대회 논문집
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• pp.1291-1296
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• 2008

Recently, ecological area rate system become effective due to enlargement of recognition and high intellectual standard and for ecological circulation in urban areas. Ecological area rate system is to control environmental quality of life what has grown worse in urban districts and corresponds to purposes of green building certification criteria for environmentally sound and sustainable development. Therefore, purposes of this study are to present suggestions through research of theory and comparison between ecological area rate system and green building certification criteria.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2002년도 기초기술학술발표회
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• pp.57-76
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• 2002

As piling works in urban area increasing, SIP which is low noise & vibration piling method is taking place of driven pile which has good bearing charateristics and economics. Since SIP has been used for more than 15 years and it's application is increasing year by year, however, accurate analysis of bearing mechanism of SIP is not enough. So the design of SIP is much more conservative than driven pile. This paper is aimed to analyse the bearing charateristics of 103 SIPs constructed in Korea to give rational design criteria. Research result shows that bearing capacity of SIP is 40% lower than that of driven pile and conservative Meyerhof(equation omitted) method produced closer result to load test results than other design method. And this result show that to use optimised design criteria for the economic SIP design, quality control criteria must be settled down to produce high in-situ bearing capacity.

• 대한조선학회논문집
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• 제39권4호
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• pp.60-65
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• 2002

본 연구는 Form Parameter를 만족하는 선형 생성 과정을 최적화 과정으로 취급하였다. 목적함수는 fairness 기준을 도입하고 설계변수는 B-spline 곡선의 조정점으로 하며 제약조건은 설계자에 의해서 주어지는 기하학적 형상으로 하였다. 최적화 방법은 GA(Genetic Algorithm)와 최적성 기준(optimality criteria)을 병행하였다.

• 제어로봇시스템학회논문지
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• 제15권11호
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• pp.1071-1075
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• 2009

This article describes a robust control method by using peak control of a sensitivity function in the state-feedback control systems. This method apparently reduces the peak, and as a result makes closed loop systems more stable. The designed closed loop systems also make the response to an external step disturbance more fast with a lower undershoot. At the conclusion, it is verified that the proposed method enhances robust stability and robust performance to parametric uncertainties through $\mu$-plot.

• 한국해양생명과학회지
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• 제9권1호
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• pp.9-21
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• 2024

마비성 패류 독소(Paralytic shellfish poisoning, PSP)는 유해 조류에 의해 생성되며, 독소에 노출된 수산물을 섭취하였을 때 중독이 발생한다. 수산물 중 PSP를 검출하는 표준 시험법인 Mouse bioassay (MBA)는 낮은 검출한계와 동물 윤리 문제로 대체 시험법의 개발 필요성이 대두되고 있다. 이러한 대체 시험법 중, PSP가 신경 세포막의 Na⁺ 채널을 차단하는 기전을 이용한 마우스 뇌신경 모세포종 세포 기반 시험법(Neuro-2a assay)의 표준화를 위한 노력이 대두되고 있다. Neuro-2a assay의 원리는 Neuro-2a 세포주에 Na⁺/K⁺ ATPase 억제제인 Ouabain(O)과 Na⁺ 채널 활성화제인 Veratridine (V)을 처리하여 과도한 Na⁺ 유입으로 인한 세포사멸을 유도한 상태에서, Na⁺ 채널 억제제인 PSP를 처리하게 되면 Na⁺ 유입이 차단되어 세포가 생존하는 것을 측정하는 것이다. 본 연구에서는 PSP 검출을 위한 Neuro-2a assay를 국내 연구 환경에 맞게 다양한 매개변수를 개선하여 최적 시험법을 확립하고자 하였다. 고려한 매개변수들은 세포밀도, 배양 조건 및 PSP 처리 조건 등으로, 그 결과는 아래와 같다. 초기 세포밀도는 40,000 cells/well로, 세포 배양시간 및 처리시간은 각각 24시간으로 설정하였다. 또한 최적 O/V 농도는 500/50 μM로 설정하였다. 본 연구에서 PSP 중 Saxitoxin (STX)에 대해서 O/V 처리가 된 상태에서 S자형 용량-반응 그래프가 도출되는 8가지 농도(368~47,056 fg/μl)를 확인하였고, Neuro-2a assay의 실험실 간 변동성 비교를 통해, 실험의 적정성 확인을 위한 5가지 Quality Control Criteria와 실험 데이터의 신뢰가능 범위(Data Criteria) 6가지를 설정하였다. 확 립된 조건으로 Neuro-2a assay를 진행한 결과 반수영향농도(EC₅₀) 값은 약 1,800~3,500 fg/μl로 나타났다. 실험실 간 변동성 비교 결과, Quality Control Criteria 값 및 Data criteria 값의 변동계수(coefficients of variation (CVs))가 1.98~29.15% 범위로 산출되어 실험의 적정성 및 재현성이 확인되었다. 본 연구를 통해 우리나라에서 활용할 수 있는 PSP 검출용 Neuro-2a assay 시험법의 최적 조건 및 5가지 Quality control 기준을 제시하였고, PSP 중 대표적인 독소인 STX을 대상으로 Neuro-2a assay를 실시한 결과 유의한 EC₅₀ 값을 산출할 수 있었으며, 향후 국내 수산물을 대상으로 MBA를 대체할 수 있는 PSP 검출법으로 활용될 것으로 기대된다.

• International Journal of Air-Conditioning and Refrigeration
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• 제14권4호
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• pp.138-146
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• 2006

Recently, a technology based on the proportional integral (PI) control have grown rapidly owing to the needs for the robust capacity of the controllers from industrial building sectors. However, PI controller generally requires tuning of gains for optimal control when the outside weather condition changes. The present study presents the possibility of reinforcement learning (RL) control algorithm with PI controller adapted in the HVAC system. The optimal design criteria of RL controller was proposed in the environment chamber experiment and a theoretical analysis was also conducted using TRNSYS program.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.2648-2653
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• 2003

This paper describes the development of a 3-DOF laparoscopic assistant robot system with motor-controlled bending and zooming mechanisms using the voice command motion control and auto-tracking control. The system is designed with two major criteria: safety and adaptability. To satisfy the safety criteria we designed the robot with optimized range of motion. For adaptability, the robot is designed with compact size to minimize interference with the staffs in the operating room. The required external motions were replaced by the bending mechanism within the abdomen using flexible laparoscope. The zooming of the robot is achieved through in and out motion at the port where the laparoscope is inserted. The robot is attachable to the bedside using a conventional laparoscope holder with multiple DOF joints and is compact enough for hand-carry. The voice-controlled command input and auto-tracking control is expected to enhance the overall performance of the system while reducing the control load imposed on the surgeon during a laparoscopic surgery. The proposed system is expected to have sufficient safety features and an easy-to-use interface to enhance the overall performance of current laparoscopy.

• 한국화재소방학회논문지
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• 제20권3호
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• pp.21-28
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• 2006

화재 시 발생하는 고온의 유독가스는 가장 주요한 사망원인이며 공기와는 다른 유체역학적 특성을 가지므로 화재실의 형상과 특징에 맞는 제연방식이 필요하고 제연설비 각 구성품은 이에 따른 일정한 성능을 요구하게 되는데, 이를 위해서는 성능시험방법과 평가기준이 정립되어 있어야 한다. 이와 관련된 국내 기준은 서류에 의한 예비검사나 부위검사 등으로 되어 있어 성능위주의 평가방법 및 기준이 미비한 실정으로 국제규격과 비교해볼 때 여러 가지 문제점을 가지고 있다. 따라서 제연설비 주요 구성품인 제연경계벽, 배연구, 송풍기, 풍도, 방연댐퍼에 대해 국내외 기준을 비교 분석하고 문제점을 도출하여 각 구성품의 성능시험방법 표준화를 위한 방안을 제시하였다.

• Korean Journal of Acupuncture
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• 제35권2호
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• pp.47-55
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• 2018

Objectives: Clinical improvements can be observed following placebo administrations in clinical trials. Randomized controlled trials have been conducted to disentangle the specific effects of therapeutic interventions over the past decade. In acupuncture trials, non-penetrating placebo needles offer the opportunity to determine the specific effects of needling. Methods: The present review provides an overview of the concept of the placebo effect and the characteristics of the placebo needles. Results: Placebo control can contribute to minimize for bias and the contextual and psychological components of therapeutic interventions. Placebo control should meet two criteria: blinding efficacy (indistinguishable from active treatment) and physiological inertness. In the case of acupuncture, however, it is difficult to meet both criteria simultaneously. The dilemma of placebo needles suggests that placebo needles do not constitute proper control in acupuncture research. Considering the characteristics of placebo needles, patients are more likely to perceive placebo needles as active treatment in acupuncture trials compared to placebo pills in pharmaceutical trials. Placebo response might be observed more frequently to placebo needles than to placebo pills. When acupuncture treatments are utilized in clinical use, placebo effects can be enhanced by exploiting patients' expectations in the contextual or environmental cues that surround medical intervention. Conclusions: We have to consider these unique characteristics of placebo needles in order to avoid drawing premature conclusions that acupuncture itself is just a placebo.