• 제목/요약/키워드: Content-based approach

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Ginsenoside-Re ameliorates ischemia and reperfusion injury in the heart: a hemodynamics approach

  • Lim, Kyu Hee;Lim, Dae-Jun;Kim, Jong-Hoon
    • Journal of Ginseng Research
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    • 제37권3호
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    • pp.283-292
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    • 2013
  • Ginsenosides are divided into two groups based on the types of the panaxadiol group (e.g., ginsenoside-Rb1 and -Rc) and the panaxatriol group (e.g., ginsenoside-Rg1 and -Re). Among them, ginsenoside-Re (G-Re) is one of the compounds with the highest content in Panax ginseng and is responsible for pharmacological effects. However, it is not yet well reported if G-Re increases the hemodynamics functions on ischemia (30 min)/reperfusion (120 min) (I/R) induction. Therefore, in the present study, we investigated whether treatment of G-Re facilitated the recovery of hemodynamic parameters (heart rate, perfusion pressure, aortic flow, coronary flow, and cardiac output) and left ventricular developed pressure (${\pm}dp/dt_{max}$). This research is designed to study the effects of G-Re by studying electrocardiographic changes such as QRS interval, QT interval and R-R interval, and inflammatory marker such as tissue necrosis factor-${\alpha}$ (TNF-${\alpha}$) in heart tissue in I/R-induced heart. From the results, I/R induction gave a significant increase in QRS interval, QT interval and R-R interval, but showed decrease in all hemodynamic parameters. I/R induction resulted in increased TNF-${\alpha}$ level. Treatment of G-Re at 30 and $100{\mu}M$ doses before I/R induction significantly prevented the decrease in hemodynamic parameters, ameliorated the electrocardiographic abnormality, and inhibited TNF-${\alpha}$ level. In this study, G-Re at $100{\mu}M$ dose exerted more beneficial effects on cardiac function and preservation of myocardium in I/R injury than $30{\mu}M$. Collectively, these results indicate that G-Re has distinct cardioprotectective effects in I/R induced rat heart.

Phenomenological study on the Structure and Essence of Deviant Peer Experiences of the Teenagers (청소년의 비행또래에 대한 구조와 본질에 관한 현상학적 연구)

  • Chang, Jung-Yeon
    • The Journal of the Korea Contents Association
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    • 제14권4호
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    • pp.211-226
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    • 2014
  • The purpose of this research is to reveal the essential meaning of deviant peer through Phenomenological approach method on experiences of the teenagers. For an in-depth understanding of the experience world of the teenagers, researcher sought the essential meaning structure about the four Life-world Existentials of constructing human's live-world. Data had been collected through the researcher, the participants' observation, field note, content analysis, as well as in-depth interview "With them. Based on an analytical process of hermeneutical phenomenology of van Manen, researcher analysed essential meanings of the data in light of the four Existential categories through separating thematic statement, decision of essential theme and rewriting. The structure of the deviant peer experienced by the teenagers has been analyzed by the hermeneutical phenomenology so as to extract 28 composition meanings, 30 phenomenon and 18 structure of experience. The results examined by each theme are as follows. This study demonstrates that essential meaning structure of the study participants in the world is the experience of boundary, alert'.

The Influencing Factors forming the Atmosphere of Ward (병실 분위기 조성에 영향을 주는 요인)

  • 윤정인;이미라
    • Journal of Korean Academy of Nursing
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    • 제25권4호
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    • pp.641-652
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    • 1995
  • Working as nurses, authors found that some patients were not content with their hospital life. Some patients wanted to move to another ward, and others complained about their ward atmosphere. In spite of patients' discomfort, nurses didn't know what made some patients complain about their ward. So, authors tried to find factors that influence atmosphere of hospital wards of the neurosurgery patients. To know the atmosphere of wards, authors selected five neurosurgery ward of a university hospital in Seoul. Observation took a month. An author observed using molar approach, in the morning, in the day time, and in evening time. Authors used concealment /no intervention technique. An author checked condition of people in the wards, and observed their verbal and nonverbal communication behavior their activities and environmental characteristics, and interpreted their meaning through ethnographic research methodology by Spradly. Authors found there was an important factors that influence the atmosphere of ward. It was a human and his attitude. At least one person who was willing to help others made ward atmosphere better. Helping others physically whenever needed, sup-porting the depressed emotionally, offering foods, or talking to others friendly brought good atmosphere. On the contrary, if everyone was indiffernt to others, the atmosphere became cold. Self-centered or selfish behaviors such as occupying too much area, using the toilet too long, covering other's suction bottle without permission and seeing others delicate or urinate were hurtful. In addition to the attitude of patients and their families, unkindness of medical teams including nurses and doctors and tasteless meal caused bad ward atmosphere. Based on this research finding, authors suggest the followings. A For the better atmosphere of ward 1. Nurses should try to make the ward atmosphere better by introducing new patient to older ones. 2. Every ward should have dividing curtains to keep patient's privacy. 3. All hospital personnel should be kind enough to make patients feel that they are repected. 4. Hospital should serve high quality meals to patients. 5. Patients had better stay with those in the similar condition. B. For the future studies 1. Repeated researches are necessary to check reliability of this results. 2. Researches for patients in different area such as ICU, or hemodialysis unit are necessary.

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Study on Development of Framework of Company Classification in Information Security Perspective (정보보호 관점의 기업 유형 분류 프레임워크 개발에 관한 연구)

  • Kim, Hee-Ohl;Baek, Dong-Hyun
    • Journal of Korean Society of Industrial and Systems Engineering
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    • 제39권3호
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    • pp.18-29
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    • 2016
  • For most organizations, a security infrastructure to protect company's core information and their technology is becoming increasingly important. So various approaches to information security have been made but many security accidents are still taking place. In fact, for many Korean companies, information security is perceived as an expense, not an asset. In order to change this perception, it is very important to recognize the need for information security and to find a rational approach for information security. The purpose of this study is to present a framework for information security strategies of companies. The framework classifies companies into eight types so company can receive help in making decisions for the development of information security strategy depending on the type of company it belongs to. To develope measures to classify the types of companies, 12 information security professionals have done brainstorming, and based on previous studies, among the factors that have been demonstrated to be able to influence the information security of the enterprise, three factors have been selected. Delphi method was applied to 29 security experts in order to determine sub items for each factor, and then final items for evaluation was determined by verifying the content validity and reliability of the components through the SPSS analysis. Then, this study identified characteristics of each type of eight companies from a security perspective by utilizing the developed sub items, and summarized what kind of actual security accidents happened in the past.

A Study on Realization of Teaching Material of Watershed Water Environmental Education by Inquiry with the Perspective of Environmental Education - Focusing on the Watershed Musim Cheon (Stream) - (환경교육적 탐구를 통한 유역 중심의 물 환경교육 교재화 연구 - 무심천 유역을 중심으로 -)

  • Heo, Jin-Sook;Lee, Du-Gon
    • Hwankyungkyoyuk
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    • 제21권4호
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    • pp.25-39
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    • 2008
  • The purpose of this study is to realize the teaching material, which develops the Model of Watershed Water Environment Education(EE) Textbook, by seeking for a method of the Inquiry with the Perspective of EE and by questing for the contents of watershed water environment necessary for Water EE with the Perspective of EE. First, the value of watershed EE was reilluminated through the literature analysis on the watershed. And 'Inquiry with the Perspective of EE' methodology was newly presented that quests for the contents necessary and proper for EE from the viewpoint of EE. Also, with suggesting it as concept and methodology of 'Inquiry with the Perspective of Watershed EE' by considering the value of EE in Water EE, it presented the content approach direction in the inquiry and the contents of the specific inquiry. Second, through the Inquiry with the Perspective of EE into water environment of the watershed Musim cheon (stream), which is a case region, it allowed the watershed water environment to be able to be synthetically understood. As for a sphere of the inquiry, 5 spheres were sought by taking into account a relation to a human being, as well as the water environment itself of the watershed Musim cheon (stream). Third, Based on the contents of the Inquiry with the Perspective of EE into the watershed Mlisim cheon (stream), 'the Model of Watershed Water EE Textbook' for middle-school students was developed. This model of textbook was selected largely four parts, and was organized with 10 learning objectives and 11 activities.

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A Study on Family Perception, Gender-Role Values, Elderly Parent Support Values of Vietnamese Women (베트남 여성의 가족 인식, 성역할가치관, 노부모 부양가치관에 대한 탐색적 연구)

  • Lee, Eunjoo;Jun, Mikyung
    • Journal of Families and Better Life
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    • 제34권3호
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    • pp.129-145
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    • 2016
  • This study focuses on the differences in family values, which is a cause of family dissolution and conflicts of marriage immigrant women. This study was conducted on 441 women in Vietnam. It was done to explore their family values. Specifically, the following were examined: the overall family values and martial status of Vietnamese women; differences in their family values by region (northern, central, southern). The survey questionnaire consists of the following content: 'family perception'; 'gender-role values'; 'elderly parent support value'. The characteristics of family values of Vietnamese women are as follows. First, the scope of family perceived by them was relatively narrow. In particular, most of them didn't perceive the parents of a spouse as a familymember. Second, in terms of gender-roles, they perceived men and women as equal and didn't have strong perception of traditional gender roles. Third, they felt strongly about supporting elderly parents. The perception of supporting elderly parents is based on equal gender roles, instead of the paternalistic approach. They preferred financial support to living with parents. There were also differences in family values by region. Also, their values seemed to be the opposite of the ones well-known by region. In addition, their values were changing amid economic growth and modernization. Residents in Can Tho in the south - known to have open-minded Southeast Asian values - had the most patrilineal, traditional values with strong perception towards supporting elderly parents. Residents in Hanoi in the north - known to have heavy influence of Confucian culture - had non-traditional values with positive attitude towards liberal sex culture, divorce, and remarriage. Residents in Da Nang, a central region, had a mixture of northern and southern characteristics in terms of family values.

Combined Effects of Curcumin and (-)-Epigallocatechin Gallate on Inhibition of N-Acylhomoserine Lactone-Mediated Biofilm Formation in Wastewater Bacteria from Membrane Bioreactor

  • Lade, Harshad;Paul, Diby;Kweon, Ji Hyang
    • Journal of Microbiology and Biotechnology
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    • 제25권11호
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    • pp.1908-1919
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    • 2015
  • This work investigated the potential of curcumin (CCM) and (-)-epigallocatechin gallate (EGCG) to inhibit N-acyl homoserine lactone (AHL)-mediated biofilm formation in gram-negative bacteria from membrane bioreactor (MBR) activated sludge. The minimum inhibitory concentrations (MICs) of CCM alone against all the tested bacteria were 200-350 μg/ml, whereas those for EGCG were 300-600 μg/ml. Biofilm formation at one-half MICs indicated that CCM and EGCG alone respectively inhibited 52-68% and 59-78% of biofilm formation among all the tested bacteria. However, their combination resulted in 95-99% of biofilm reduction. Quorum sensing inhibition (QSI) assay with known biosensor strains demonstrated that CCM inhibited the expression of C4 and C6 homoserine lactones (HSLs)-mediated phenotypes, whereas EGCG inhibited C4, C6, and C10 HSLs-based phenotypes. The Center for Disease Control biofilm reactor containing a multispecies culture of nine bacteria with one-half MIC of CCM (150 μg/ml) and EGCG (275 μg/ml) showed 17 and 14 μg/cm2 of extracellular polymeric substances (EPS) on polyvinylidene fluoride membrane surface, whereas their combination (100 μg/ml of each) exhibited much lower EPS content (3 μg/cm2). Confocal laser scanning microscopy observations also illustrated that the combination of compounds tremendously reduced the biofilm thickness. The combined effect of CCM with EGCG clearly reveals for the first time the enhanced inhibition of AHL-mediated biofilm formation in bacteria from activated sludge. Thus, such combined natural QSI approach could be used for the inhibition of membrane biofouling in MBRs treating wastewaters.

Effective Keyword Search on Semantic RDF Data (시맨틱 RDF 데이터에 대한 효과적인 키워드 검색)

  • Park, Chang-Sup
    • The Journal of the Korea Contents Association
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    • 제17권11호
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    • pp.209-220
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    • 2017
  • As a semantic data is widely used in various applications such as Knowledge Bases and Semantic Web, needs for effective search over a large amount of RDF data have been increasing. Previous keyword search methods based on distinct root semantics only retrieve a set of answer trees having different root nodes. Thus, they often find answer trees with similar meanings or low query relevance together while those with the same root node cannot be retrieved together even if they have different meanings and high query relevance. We propose a new method to find diverse and relevant answers to the query by permitting duplication of root nodes among them. We present an efficient query processing algorithm using path indexes to find top-k answers given a maximum amount of root duplication a set of answer trees can have. We show by experiments using a real dataset that the proposed approach can produce effective answer trees which are less redundant in their content nodes and more relevant to the query than the previous method.

Dehydration of foamed sardine-starch paste by microwave heating. (Formulation and processing conditions) (고주파가열을 이용한 정어리 발포건조제품의 가공 I. 첨가물의 배합 및 가공방법)

  • 이병호
    • Journal of the Korean Professional Engineers Association
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    • 제17권3호
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    • pp.22-31
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    • 1984
  • Sardine ant mackerel so called dark muscled fish have been underutilized due to the disadvantages in bloody meat color, high content of fat, and postmortem instability of protein. Recent efforts were made to overcome these defects and develope new types of product such as texturized protein concentrates and dark muscle eliminated minced fish. Approach of this study is based on the rapicl dehydration of foamed fish-starch paste by dielectric heating. In process comminuted sardine meat was washed more than three times by soaking and decanting in chilled water and finally centrifuged. The meat was ground in a stone mortar added with adequate amounts of salt, foaming agent, and other ingredients for aid to elasticity and foam stability. The ground meat paste was extruded in finger shape and heated in a microwave oven to give foamed, expanded, and porous solid structure by dehydration. Dielectric constant ($\varepsilon$′) and dielectric loss ($\varepsilon$") vcalues of sardine meat paste were influenced by wavelength and moisture level. Those values at 100KHz and 15MHz were ranged 2.25∼9.86 ; 2.22∼4.18 for $\varepsilon$′ and 0.24∼19.24 ; 0.16∼1.25 for $\varepsilon$", respectively, at the moisture levels of 4.2∼13.8%. For a formula for fish-starch paste preparation, addition of 20∼30% starch (potato starch) to the weight of fish meat, 2∼4% salt, and 5∼10% soybean protein was adequate to yield 4∼5 folds of expansion in volume when heated. Addition of egg yolk was of benefit to micronize foam size and better crispness. In order to provide better foaming and dehydration, addition of 0.2∼0.5% sodium bicarbonate foaming agent, was proper to result in foam size of 0.5∼0.7mm and foam density of 200∼400/$\textrm{cm}^2$ which gave a good crispness.

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Classification and Analysis of the Project Contents and Expected Effects of Urban Regeneration Pilot Projects (도시재생 선도지역의 사업내용 및 기대효과 유형 분류 및 분석 -근린재생형 도시재생 선도지역 마중물 사업을 대상으로-)

  • Bae, Min-Kyung;Park, Seung-Hoon
    • The Journal of the Korea Contents Association
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    • 제18권10호
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    • pp.527-544
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    • 2018
  • Urban regeneration is a project to enhance the competitiveness. Therefore, it is necessary to examine the contents and expected effects of urban regeneration projects. In this study, we classified and analyzed the contents and expected effects of the 11 neighborhood urban regeneration pilot projects. The main results are as follows; First, physical regeneration is the most popular in terms of project contents, and social approach is the most typical for the expected effects. Second, the project of social regeneration is mainly focused on strengthening the capacity of residents. Third, the most expected effect of physical regeneration was about the improvement of landscape. Fourth, the most expected effect of social regeneration was the contents of residents' participation. Finally, there is a need for the development of projects that can expect a combination effects rather than a single effect. The urban regeneration new deal projects need to pay more attention to projects that can have various effects based on the development of competitive urban contents.