• 대한교통학회지
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• 제30권3호
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• pp.7-15
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• 2012

보행시설의 보행 LOS 산정시 한국도로용량편람의 방법론을 주로 사용하고 있는데, 지나치게 양호한 결과가 도출된다는 문제점이 지속적으로 지적되어 왔다. 이에 본 연구의 목적은 현재 널리 이용되고 있는 한국도로용량편람의 보행 LOS 분석방법에 대한 문제점을 파악하고, 서울시 사례를 이용하여, 다양한 보행시설 중 보도의 보행 LOS 분석방법에 대한 개선방안을 제시하는 것이다. 한국도로용량편람의 분석방법에 의해 서울시 보도의 보행 LOS를 진단한 결과, 전체 대상지점의 90%이상이 LOS A로 판정되어 지나치게 양호한 결과가 도출되었는데, 이의 개선방안으로 유효보도폭의 절대적 값을 고려하는 방안을 제시하였다. 그 결과 LOS C 및 LOS D에서 많은 변화가 나타나는 것을 알 수 있었다. 지금까지 보도를 대상으로 한 보행 LOS 진단 연구가 한정된 지역에 국한되어 진행되었다면 본 연구는 서울시 전역을 대상으로 하여 보도의 보행 LOS를 진단했다는 면에서도 의의가 있다고 할 수 있다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권2호
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• pp.108-115
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• 2020

Objectives: Kinesiology tape (KT) creates a pulling force on the skin, thus improving blood and lymph flow by alleviating hemorrhage and congestion of lymphatic fluid. The authors hypothesized that the use of KT could be beneficial for the management of complications after head and neck surgery and designed this study to evaluate the effects of KT on swelling, pain, and trismus after enucleation of mandibular dentigerous cysts with third molar extraction. Materials and Methods: Forty patients who underwent enucleation of a dentigerous cyst with extraction of the mandibular third molar were selected. The patients were randomized into two groups (n=20 each): a KT group, where KT was applied after surgery in addition to basic postoperative care, and a control group, where patients received basic postoperative care without KT application. Swelling, pain, and trismus were evaluated before surgery (T0) and on postoperative days 1 (T1), 2 (T2), and 3 (T3). Cyst volume, gauze weight for assessing bleeding, and operation time were recorded. Results: There was a significant difference between the two groups in the change in swelling up to T1 and the change in swelling between T1 and T2. The maximum swelling in the KT group was significantly less than that in the No-KT group and maximum swelling appeared faster in the KT group than in the No-KT group. Both groups showed a mild pain response but there was no significant difference between the two groups. There was no significant difference on interincisal distance change between the two groups. There were no correlations between cyst volume, bleeding, operation time, and maximum swelling. Conclusion: KT can effectively manage facial swelling after oral and maxillofacial surgeries such as cyst enucleation and third molar extraction, thus improving postoperative patient satisfaction levels and quality of life.

• 한국시뮬레이션학회논문지
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• 제17권3호
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• pp.63-73
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• 2008

P제철은 수심, 하역장비 및 야드와의 Belt Conveyer 연결 가능성 등에 따라 3만톤급이 접안 가능한 선석에서부터 25만 톤급 선박이 접안 가능한 선석을 각각 운영하고 있다. 또한 3만톤급에서 25만 톤급의 Bulk선을 운영하고 있는데, 해상운임을 줄이기 위해 15만톤 이상의 대형선 배선비율을 증가하여 왔다. 그리고 선형별 흘수 및 선폭에 따라 접안 가능한 선석이 제한되기 때문에 대형선의 배선비율 증가는 특정 선석의 선석점유율 증가 요인이 되고, 선석점유율이 증가하면 결과적으로 대형선의 대기시간이 증가하여 체선료가 증가한다. 일반적인 대기이론에서 선석점유율이 일정 수준이 이상이 되면 대기시간이 급격이 증가하지만, P제철 원료부두의 경우 부두운영 및 선석운영 계획을 직접 수행함으로써 선박도착 및 하역생산성의 변동성이 적고 선박도착이 정시성이 확보되어 선석점유율 증가에 따른 선박대기 시간이 일반 대기이론에서 언급하고 있는 것보다 증가율이 낮다.

• 한국공간정보시스템학회 논문지
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• 제9권3호
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• pp.25-33
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• 2007

교통체증을 줄이고 접근성을 높이기 위해 국내 대도시들은 대중교통 위주의 정책에 중점을 두고 있다. 대중교통망을 개선하기 위해서는 적절한 접근성의 분석방법이 필요하게 된다. 기존의 접근성에 관한 연구들은 대부분 존(zone) 레벨에서 이루어진데 비해 본 연구에서는 버스루트나 정류장과 같이 세부레벨에서의 대안적인 접근성측정 방법을 제시한다. 시종점 경로를 구성하는 수단들의 최적의 조합을 산출하고 이들의 접근성을 토폴로지에 기반한 방법으로 측정한다. 시종점루트와 최적조합을 산출하는데에는 GA(유전자알고리즘)가 사용되었으며, 접근성 산출에는 space syntax 이론이 적용되었다. 본 연구에서는 일반적으로 수작업으로 그려지는 space syntax의 axial line 대신 GIS의 nodelink 데이터를 사용하였다. 최종적으로 산출된 접근성은 O-D 데이터를 이용하여 캘리브레이션하였으며, 서울 강남지역에 적용하여 예시하였다.

• 동의생리병리학회지
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• 제24권3호
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• pp.463-469
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• 2010

This research is performed to obtain positive evidences of Mori cortex, a kind of oriental medicinal herbs, in the cellular levels. The extracts of M. cortex have shown anti-inflammatory effects against cutaneous inflammation and clinical effects on pulmonary asthma and congestion in oriental medicine. Thus BV2 cells were chosen because microglia are considered as the main immunocompetent cells in the central nervous system. Lipopolysaccharide (LPS)-induced microglial activation of cultured BV2 cells and subsequent release of nitric oxide (NO) and Prostaglandin E2 (PGE2) were effectively suppressed by methylene chloride extract of Morus alba L. (MEMA). From the inflammation-mediated mRNA and protein analyses, we showed that inducible NO synthase (iNOS), cyclooxygenase-2 (COX-2), interleukin-$1{\beta}$ (IL-$1{\beta}$) and tumor necrosis alpha (TNF-${\alpha}$) induced by LPS were markedly decreased by MEMA treatment. From the observation of nuclear factor-kB (NF-${\kappa}B$) which is controlling and mediating inflammation through COX-2 and iNOS, there showed that p65, a subunit of NF-${\kappa}B$, was increased in nuclear and $I{\kappa}B$, a competitor of NF-${\kappa}B$, was recovered in cytosol after MEMA treatment. These are corresponding with results of iNOS, COX-2, IL-$1{\kappa}$ and TNF-${\alpha}$, and confirm some suppressive effect against transcriptional activation of NF-${\kappa}B$. In conclusion, the anti-inflammatory action of M. cortex against BV2 microglia cells is expected to protect nerve tissues through suppression of neuronal inflammation in various neurodegenerative diseases.

• 대한한방종양학회지
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• 제8권1호
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• pp.9-21
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• 2002

Object The effect of Banhasasim-tang extracts on the hepatic, splenic toxicity and induced by Doxorubicin administration(Three injection protocol) were monitored using male ICR mice. Method The changes of body weigh, organ weights of liver and spleen were observed with blood GOT and GPT level. Results 1. Increase of absolute and relative liver weight observed in Doxorubicin treatment group were dose-dependently inhibited by Banhasasim-tang extracts. In addition, the degrees of liver congestion and necrotic spot were significantly and dose-dependently decreased after Banhasasim-tang extracts dosing groups compared to that of Doxorubicin treatment group. It is also demonstrated that elevated serum GOT and GPT levels in Doxorubicin treatment group were significantly decreased in Banhasasim-tang extracts dosing groups. 2. Decrease of absolute and relative spleen weight observed in Doxorubicin treatment group were dose dependently inhibited by Banhasasim-tang extracts. In addition, the degrees of splenic atrophy were significantly and dose-dependently decreased after Banhasasim-tang extracts dosing groups compared to that of Doxorubicin treatment group.

• 대한본초학회지
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• 제25권2호
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• pp.41-54
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• 2010

Objectives : This study was carried out to investigate the anti-toxicity effect of Hwangryunhaedoktang on the dried Mylabris phalerata extract containing cantharidin in ICR mouse. Methods : Dried Mylabris phalerata extracts were orally administered at dosage level 2000, 1000, 500, 250 and 125mg/kg, respectively with and/or without administration of Hwangryunhaedoktang 200mg/kg. During 2 weeks, the changes of body weight, mortality, $LD_{50}$, macroscopic changes of gastrointestinal tract and liver, changes of serum gastrin and somatostatin levels were observed. Results : Decrease of body weight gains was observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Increase of mortality rates was observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. The $LD_{50}$ of dried Mylabris phalerata extract in male mice significantly increased in a case of concomitant used of Hwangryunhaedoktang 268.86 vs 662.05mg/kg. Clinical signs were observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging after dosaging. Increase of number of hemorrhagic and/or erythematous spots in the gastrointestinal tracts, enlargement and congestion in the liver were observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Increase of serum gastrin level was observed in dried Mylarbis phalerata extract-dosing groups, these state of abnormal increase was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Decrease of serum somatostatin level was observed in dried Mylabris phalerata extract-dosing groups, these state of abnormal decrease was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Conclusions : We could conclude that the Hwangryunhaedoktang has anti-toxicity effect on the dried Mylabris phalerata extract containing cantharidin.

• 대한한방부인과학회지
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• 제21권4호
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• pp.69-89
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• 2008

Purpose: This study was performed to evaluate anti-oxidant activities and anti-inflammatory effects of Sungyoutanggagambang(SYTG). Methods: In the study of anti-oxidant activities. SYTG was investigated by DPPH radical scavenger activity. superoxide dismutase activity and superoxide anion radical scavenger activity. In the study of anti-inflammatory effects. SYTG was investigated using cultured cells and murine models. As for the parameters of inflammation. levels of several inflammatory cytokines and chemical mediators which are known to be related to inflammation were measured in mouse lung fibroblast cells(mLFCs) and RAW264.7 cells. Results: Prior to the experiment. we investigated the security of SYTG by measuring GOT and GPT in serum. 1. SYTG showed high antioxidant activity in a concentration-dependent degree by measured scavenging activity of DPPH free radical, superoxide dismutase and superoxide anion radical. 2. SYTG inhibited IL-1$\beta$, IL-6. TNF-$\alpha$, COX-2 and NOS-II mRNA expression as compared with the control group in a concentration-dependent degree in RAW264.7 cell line. 3. SYTG inhibited IL-1$\beta$, IL-6 production significantly at 100 ${\mu}g/ml$ and TNF-$\alpha$ production significantly at 50, 100 ${\mu}g/ml$ as compared with the control group in RA W264.7 cell line. 4. SYTG inhibited IL-1$\beta$, and IL-6 production significantly as compared with the control group in serum of acute inflammation-induced mice. and decreased IL-1$\beta$, IL-6 production in spleen tissue. and also decreased IL-1$\beta$, IL-6 production in liver tissue. Conclusion: These results suggest that SYTG can be useful in treating diverse female diseases caused by inflammation such as endometrosis, myoma, pelvic congestion. chronic cervicitis, chronic pelvic inflammatory disease and so on.

• 한국빅데이터학회지
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• 제6권1호
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• pp.1-12
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• 2021

모바일 기반 온라인 쇼핑의 급성장과 COVID-19로 인해 시작된 비대면 비즈니스의 성장은 택배와 같은 물류 서비스 수요를 폭발적인 증가를 이끌어냈다. 급격하게 성장한 수요에 대응하기 위해 대부분의 물류·유통기업들은 도심 내 풀필먼트 센터 구축을 통한 고객 서비스 수준 향상을 위해 노력하고 있다. 그러나, 높은 지가와 교통 체증 등과 같은 사회적 요인에 의해 도심 내 풀필먼트 센터를 확보하는 데 큰 어려움을 겪고 있다. 본 연구에서는 향후 고속도로에 스마트톨링 서비스가 전면 확대됨에 따라 유휴부지로 전환될 요금소 부지를 공유물류센터로 전환하기 위한 후보지 선정 방안을 제시한다. 이를 위해 사회연결망 분석을 통해 각 후보지들의 중심성을 분석하였으며, 중심성 평가의 특성에 따른 결과의 해석을 위한 네트워크 구조를 거리기반과 시간기반의 두 가지 방법으로 재설계하여 평가하였다. 누적된 중요도를 기준으로 적정 후보지 군을 선택하는데 활용될 수 있을 것이다.

• 한국전자통신학회논문지
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• 제16권4호
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• pp.653-660
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• 2021

재생에너지 자원은 비용감소, 정부 보조금, 지속가능성 등의 목적에 연계되어 전 세계적으로 전기를 생산하는 설비의 필수적인 영역으로 급속하게 진행되고 있다. 풍력, 태양광 및 부하가 상호작용하여 발생하는 예측오차는 배전계통, 선로 혼잡도, 전압과 무효전력 안정도 여유 등 예기치 않은 심각한 충격을 발생시킬 수가 있다. 이 충격은 전력계통에서 변동성 재생에너지의 보급이 증가함에 따라 더 커질 것이다. 우리나라는 배전선로에 연결될 수 있는 재생에너지의 최대 용량은 송배전용전기설비이용규정에 의해 제한된다. 이 연구는 기존 송전설비의 중대한 설비 개조가 필요하지 않는 배전선로에 대한 연계용량 결정방안을 기술한다. 특히 선로 케이블의 연계용량 기준과 배전선로의 최소부하 계산에 관하여 제안과 검토를 한다.