• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3163-3168
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• 2013

Methylenetetrahydrofolate reductase (MTHFR) plays a central role in folate metabolism. This study with 381 esophageal cancer patients and 432 healthy controls was conducted to examine the association of MTHFR C677T and A1298C polymorphisms with susceptibility to esophageal cancer (EC) in a Chinese population. Compared with the CC genotype of MTHFR C677T, subjects carrying homozygote TT and variant genotypes (CT+TT) demonstrated reduced risk of EC with adjusted ORs (95% CI) of 0.44 (0.28-0.71) and 0.57 (0.37-0.88), respectively. However, no association was found between the MTHFR A1298C polymorphism and the risk of EC. Comparing to haplotype CA, haplotypes TA and TC could reduce the susceptibility to EC with adjusted ORs (95% CI) of 0.61(0.47-0.79) and 0.06 (0.01-0.43), respectively. In conclusion, the present study suggested that the MTHFR C677T polymorphism can markedly influence the risk of EC in Chinese.

• Preventive Nutrition and Food Science
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• v.11 no.4
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• pp.318-322
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• 2006

The objective of this experiment was to investigate the effect of extrusion of ginseng roots in twin screw extruder on susceptibility of ginseng starch toward hydrolysis by ${\alpha}-amylase$ BAN 480L (Novozyme, Denmark) and cellulase Celluclast 150L and saccharification by amyloglucosidase AMG-E (Novozyme, Denmark). The extrusion was conducted at 22% and 30% moisture contents of feed at screw speed 300 rpm. Barrel temperature at zone 1 was adjusted at $100^{\circ}C$ and $120^{\circ}C$. The results showed that extrusion process improved the ginseng ${\alpha}-amylase$ susceptibility as compared to traditionally dried ginseng (white and red ginseng). Reducing sugar of hydrolyzed extruded samples was 2,500% of its initial concentration, whereas the reducing sugar of hydrolyzed non-extruded sample was only 200% of its initial concentration. However, addition of cellulase during liquefaction lowered the saccharification yield of both non-extruded and extruded samples as well.

• Korean Journal of Veterinary Service
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• v.17 no.2
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• pp.89-94
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• 1994

The present study was conducted to investigate the incidence of pasteurella multocida(p. multocida) infection and some properties of the isolated organisms from the swine herds in Eastern Kangwon during the periods from March 1993 to November 1993. The results obtained were summerized as follows： 1. The lungs of 180 slaughtered pigs were sampled and p. multocida was isolated from 38 pigs (21.1%) and cultured positive. 2. The majority of biochemical md cultural properties of the p. multocida isolates were identical to those of the standard strains. 3. We investigated the capsular serogroup and drug susceptibility of 38 Isolates of p. multocida from pigs with pneumonic lesions 4. p. multocida isolateds were typed for capsular serogroupes A by hyaluronidase inhibition of capsule and D by acriflavin auto agglutination. Most isolates(55.3%) were type A, 15.8% were type D, and the remaining 28.9％ were untypable 5. In antimicrobial susceptibility test these isolates of p. multocida were susceptible in order of colistin(94.7%), ampicillin(94.7%), cepalothin(92.1%). gentamicin(92.1%), amikacin(89.5%), but the majority of them were resistant in order of neomycin(26.3%), teracycline(23.7%), streptomycin( 15.8%)

• Korean Journal of Veterinary Research
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• v.45 no.4
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• pp.563-568
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• 2005

The present study was conducted to investigate biochemical characteristics and antimicrobial susceptibility of Aeromonas hydrophilia isolated from Jackass penguins (Spheniscus demersus) of zoo and capelins (Mallotus villosus). Seven of Jackass penguins showed anorexia, depression with seriously greenish vomiting for a few days, but resulted in 4 deaths although extensive treatment was carried out by zoo veterinarians. From the 18 samples composed of organs or feces from dead or live Jackass penguins and capelins, 4 (22.2%) Aeromonas hydrophilia were isolated and Bacillus spp, Staphylococcus aureus, Staphylococcus auricularis, Staphylococcus cohnii and Enterobacter aminigenus were also identified. Antimicrobial susceptibility tests of Aeromonas hydrophilia showed that all isolates were susceptible to amikacin, gentamicin, kanamycin, norfloxacin and trimethoprim- sulfadimethoxazole. However, all isolates were resistant to the following antimicrobials; ampicillin, bacitracin, c ephalothin, cefazolin, noboviocin, penicillin and vancomycin.

• Journal of Korean society of Dental Hygiene
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• v.13 no.2
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• pp.193-200
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• 2013

Objectives : The purpose of this study was to examine influential factors related to hand washing practice in dental hygienists by health belief model, one of the major predictors of health behavior including perceived susceptibility, perceived seriousness, perceived benefits, perceived barriers and cues to action. Methods : The subjects were dental hygienists in dental hospitals, dental clinics, general hospitals and university hospitals in Seoul. A survey was conducted from May 1 to September 30, 2011. Results : Analysis of health belief of dental hygienists in hand washing, they revealed the highest marks of 4.39 to perceived benefits, followed by perceived susceptibility(4.29), perceived seriousness(3.94), cues to action(3.30) and perceived barriers(1.81). The mean was 4.13 in hand washing practice. The senior and well educated dental hygienists in general hospitals had a tendency to wash hands frequently. It is statistically significant(p<0.05). In regard to the correlation among the subfactors of health beliefs, susceptibility had a statistically significant positive correlation to seriousness, benefits and cues to action, and seriousness was positively correlated to benefits and cues to action. Conclusions : It is necessary to develop and implement hand washing education program for dental hygienists focusing on perceived benefits and barriers which are two of the health beliefs affecting the hand washing practice.

• Korean Journal of Occupational Health Nursing
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• v.27 no.4
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• pp.235-246
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• 2018

Purpose: This study aimed to comprehend the real context of metabolic syndrome-related factors of Korean male blue-collar workers from small-sized companies based on the health belief model. Methods: A total of 37 workers from three companies were interviewed, and three series of focus group interviews were conducted. Data were analyzed using deductive content analysis. Results: Data were classified into four categories: knowledge, perceived susceptibility and severity, perceived barriers, and beliefs. Knowledge referred to low knowledge level; perceived susceptibility and severity referred to unawareness of susceptibility and severity; perceived barriers referred to shift work, overtime work, and a social context including having no choice but to drink; and beliefs referred to believing that health promotion behaviors do not relate to preventing metabolic syndrome, believing that one cannot prevent metabolic syndrome oneself, and believing that professional help is required. Conclusion: To prevent and reduce the risk of metabolic syndrome among Korean male blue-collar workers, interventions should focus on strategies to increase metabolic syndrome-related knowledge and perceptions, social support, and self-efficacy for practicing health behaviors. In addition, it is necessary to develop policies for establishing a healthy drinking culture in companies.

• Korean Journal of Veterinary Service
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• v.41 no.4
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• pp.229-237
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• 2018

Identification of antibiotic resistant bacteria isolated from animals is necessary for seeking a proper treatment and for preventing the spread of the bacteria among animals. Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is of worldwide concern in veterinary medicine. This study was conducted to investigate the antimicrobial susceptibility of Staphylococcus pseudintermedius (S. pseudintermedius) isolated from dogs and cats. Out of the total number of 150 specimens, 35 isolates (23.3％) were identified as S. pseudintermedius when tested by MALDI-TOF MS (Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectroscopy). Among them, 5 isolates (14.3%) were the case of MRSP. In the results of the antimicrobial susceptibility test, the isolates of S. pseudintermedius were susceptible to amikacin (100%), cephalothin (100%), vancomycin (100%), amoxicillin (85.7%), oxacillin (85.7%), enrofloxacin (82.8%), chloramphenicol (80%). On the other hand, they were resistant to penicillin (71.4%), tetracycline (48.6%), ampicillin (37.1%), kanamycin (31.5%), erythromycin (31.4%), respectively.

• Journal of the Korean Society of School Health
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• v.35 no.1
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• pp.22-30
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• 2022

Purpose: Based on the Health Belief Model, this study aimed to identify factors influencing on COVID-19 vaccination intention of mothers with elementary school children by examining the relationships between perceived susceptibility, perceived severity, perceived benefit, perceived barrier, cue to action, and perceived self-efficacy. Methods: Mothers with elementary school children were recruited from three elementary schools. An online survey was conducted of 130 mothers in November, 2021. Results: As a result, the factors influencing on vaccination intention were perceived self-efficacy (β=.33), perceived susceptibility (β=.18), perceived benefit (β=.16), and perceived barrier (β=-.17). Conclusion: Based on our findings, there is a need to develop a tailored nursing intervention that enhances perceived self-efficacy, perceived susceptibility and perceived benefit while decreasing perceived barrier in order to improve vaccination intention.

• Journal of Forest and Environmental Science
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• v.39 no.4
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• pp.213-224
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• 2023

As abnormal weather events due to climate change continue to rise, landslide damage is also increasing. Given the substantial time and financial resources required for post-landslide recovery, it becomes imperative to formulate a proactive response plan. In this regard, landslide susceptibility analysis has emerged as a valuable tool for establishing preemptive measures against landslides. Accordingly, this study conducted an annual landslide susceptibility analysis using the history of landslides that occurred over many years in the Jeolla region, and analyzed areas with a high potential for landslides in the Jeolla region. The analysis employed an ensemble model that amalgamated 10 data-based models, aiming to mitigate uncertainties associated with a single-model approach. Furthermore, based on the cumulative data regarding landslide susceptible areas, this research identified regions vulnerable to recurring landslide damage in Jeolla region and proposed specific strategies for utilizing this information at various levels, including local government initiatives, adaptation plan development, and development approval processes. In particular, this study outlined approaches for local government utilization, the determination of adaptation plan types, and considerations for development permits. It is anticipated that this research will serve as a valuable opportunity to underscore the significance of information concerning regions vulnerable to recurring landslide damage.

• Pediatric Infection and Vaccine
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• v.26 no.3
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• pp.140-147
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• 2019

Purpose: Staphylococcus aureus is a major cause of skin and soft tissue infections (SSTIs). This study aimed to determine the temporal trends in antibiotic susceptibility of S. aureus in SSTI patients aged <19 years. Methods: This retrospective observational study was conducted in pediatric patients with SSTI caused by community-associated S. aureus. Microbiologic and demographic data were collected, and the trends of antibiotic susceptibility results were evaluated. Results: From January 2010 to December 2018, a total of 807 S. aureus isolates were included. An overall increase in susceptibility of isolates to oxacillin was noted (P<0.001), with 75.0% of isolates being oxacillin-susceptible in 2018. S. aureus remained highly susceptible to trimethoprim/sulfamethoxazole and tetracycline, with 97.6% and 95.2% isolate susceptibility in 2018, respectively. Isolates from younger children aged 1 to 5 years had a significantly lower rate of susceptibility to oxacillin than older children aged 6 to 18 years (53.4% vs. 75.0%, P<0.001). Conclusions: The proportion of methicillin-resistant S. aureus isolates appears to decrease in pediatric patients with community-associated SSTI caused by S. aureus. Clinicians should be aware of regional susceptibility patterns when choosing empirical regimens.