• The Korean Journal of Physiology and Pharmacology
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• v.23 no.5
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• pp.367-379
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• 2019

Although atopic dermatitis (AD) is known to be a representative skin disorder, it also affects the systemic immune response. In a recent study, myoblasts were shown to be involved in the immune regulation, but the roles of muscle cells in AD are poorly understood. We aimed to identify the relationship between mitochondria and atopy by genome-wide analysis of skeletal muscles in mice. We induced AD-like symptoms using house dust mite (HDM) extract in NC/Nga mice. The transcriptional profiles of the untreated group and HDM-induced AD-like group were analyzed and compared using microarray, differentially expressed gene and functional pathway analyses, and protein interaction network construction. Our microarray analysis demonstrated that immune response-, calcium handling-, and mitochondrial metabolism-related genes were differentially expressed. In the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology pathway analyses, immune response pathways involved in cytokine interaction, nuclear factor-kappa B, and T-cell receptor signaling, calcium handling pathways, and mitochondria metabolism pathways involved in the citrate cycle were significantly upregulated. In protein interaction network analysis, chemokine family-, muscle contraction process-, and immune response-related genes were identified as hub genes with many interactions. In addition, mitochondrial pathways involved in calcium signaling, cardiac muscle contraction, tricarboxylic acid cycle, oxidation-reduction process, and calcium-mediated signaling were significantly stimulated in KEGG and Gene Ontology analyses. Our results provide a comprehensive understanding of the genome-wide transcriptional changes of HDM-induced AD-like symptoms and the indicated genes that could be used as AD clinical biomarkers.

• Korean Journal of Child Education & Care
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• v.19 no.3
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• pp.1-12
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• 2019

Objective: This study aims to thoroughly analyze the correlation effect size between domestic violence and school violence by meta-analyzing previous studies on the correlation between school and domestic violence. Methods: For this purpose, meta-analysis was performed on the selected research material, which consists of national research data collected from various databases from 2001 to April, 2019. 16 thesis and 9 papers on the correlation between school and domestic violence were selected. A random effect model analysis based on the homogeneity examination results was performed on the selected data. Results: The results showed, just as Cohen (1977) proposed, that the correlation effect size between domestic and school violence was 0.25, which is moderate. This is a somewhat lower number than the previous studies on the same subject presented. Of the sub-categories of domestic violence, physical violence and psychological violence appeared to have a correlation effect size of 0.34 and 0.28, respectively, with physical violence showing the highest correlation effect size. Of the types of domestic violence, witnessing spouse violence and experiencing neglect appeared to have a moderate correlation size effect of 0.24. All of these results were statistically significant. Conclusion/Implications: This study utilized meta-analysis as a comprehensive and systematic method to analyze the correlation effect between domestic and school violence. The results presented may lead to discussions on the subject's social implications, limits, and propositions for future studies.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.9
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• pp.188-197
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• 2019

This study analyzed empirically the effects of the perception of outbound passengers, who flew from Korea to overseas tourist destinations, on the cabin service quality, tourist experience, and tourist satisfaction. For empirical analysis, a survey was given to Korean passengers using a national carrier of South Korea. Based on empirical analysis, the researchers judged that the analysis results and implications could be applied to inbound foreign passengers who visited Korea for the tourism purposes if researchers generated significant results from empirical analysis. This paper designed a research model that represented the meaningful relationship among, airline cabin-service quality, tourist experience, and tourist satisfaction following preceding research. According to the analysis, that factors that consisted of the cabin service quality had a significant effect on the tourist satisfaction with a mediating effect of both the cognitive and emotional tourist experience. Therefore, the perception on airline's cabin service quality of the national carrier would be a starting point that can help improve the tourist satisfaction.

• Convergence Security Journal
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• v.18 no.2
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• pp.167-177
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• 2018

Major countries, such as the U.S., UK and Germany have reformed their national intelligence systems in the face of transnational, asymmetric and comprehensive threats since September 11, 2001 and have strengthened the intelligence capacity involved in countering terrorism and WMD proliferation, right/left extremism threats. The Korean Moon Jae-in government is preparing a reform plan to eliminate illegal political intervention and abuse of power by the National Intelligence Service(NIS) and to rebuild it as an efficient national intelligence agency for national security. In discussing the reform direction of the NIS, it is necessary to discuss in detail whether adopting a separate model of intelligence agencies to restrict domestic intelligence activities of the NIS and concentrate on foreign intelligence activities or establish new domestic intelligence agencies. Second, as for the issue of transferring anti-Communism investigation authority of the NIS to the police, it needs to be carefully considered in terms of balancing the efficiency and professionalism of intelligence agency activity in the context of North Korea's continuous military provocation, covert operations and cyber threats. Third, it should strive to strengthen the control and supervision functions of the administration and the National Assembly to ensure the political neutrality of the NIS in accordance with the democratization era, to guarantee citizens' basic rights and to improve the transparency of budget execution.

• Journal of the Society of Disaster Information
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• v.17 no.2
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• pp.289-305
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• 2021

Purpose: The purpose of this study is to check the importance of higher level, sub higher level and lower alternative factor and the factor for relieved life and also check the comprehensive priority in executed "Safety and relieved life level improvement of apartment house residents by AHP analysis". Method: The safety management evaluation elements and alternatives have been arranged as hierarchical structure based on the preceding studies and the advice of experts for the maintenance and system of apartment house in this study. Study model is used for the survey of pair wise comparison composition targeting experts and AHP analysis method is used for alternative plan ranking, etc. Result: The response result of survey secured the consistency and it is confirmed that safety inspection for apartment house electricity facility is most important for higher level, safety inspection, detailed inspection and diagnosis evaluation are most important for sub higher level and plumbing equipments is most important for alternatives based on the analysis result of relative weight comparison for sub higher level and alternatives for final goal attainment of the study. Conclusion: Plumbing equipments, crime prevention safety and electrical safety are shown as top priority alternatives when observe it with expert manager's point of view for apartment house. It shows that securing the importance of living safety accident and deciding the level of relieved life can be improved are the alternatives of pre-prevention and management strengthening.

• Journal of Digital Convergence
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• v.17 no.11
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• pp.61-70
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• 2019

The The government has recently announced its mid- to long-term plans for promoting art. With the advent of the 4th industrial revolution, contemporary art contents that are integrated with Intelligent Information Technologies such as Artificial Intelligence (AI), Virtual Reality (VR), and Big Data are being introduced, and social interest in humanities and creative convergence is rising. In addition, the industrialization of the art market is expanding amid the rising popularity of art among the general public and the growing interest of art as an investment replacement system, along with the strengthening of the creative personality education of our Education Ministry. Therefore, it is necessary to establish a strategy for transparency and revitalization of the art market by providing comprehensive information such as search functions, analysis data, and criticism by writer and price. This paper has established an information system plan for the establishment of an online supply system for art transaction information, providing auction transaction information for art market, providing report and news for art market, providing public relations platform, and providing art market analysis service and membership relationship management service. To this end, the future model was established through environmental analysis and focus analysis of the art market, and strategic tasks and implementation plans were established accordingly.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.197-207
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• 2021

According to the analysis of Kolb's learning style, Korean university student pilots interpret and attach meaning to themselves. Moreover, as the school year progresses, they enter the flight-training course with a 100 % diverger style, which is a variety of thoughts and imaginative learning styles. As the school year progresses, some changes occur with accommodator (11.1%) and assimilator (15.9%) styles. On the other hand, most students remain as the diverger style (71.4%). In the case of U.S. student pilots, most in first-year are assimilator (35.5%) and converger (24.3%) styles, and the proportion of the converger style increases as the senior year is approached. In the first grade, most Chinese student pilots are assimilators (41.5%) and convergers (28.4%), but in the higher grade, the proportion of assimilators and convergers decrease, and the proportion of diverger styles increases dramatically. In the fourth grade, the accommodator was similar to the first grade, but the converger style continued to decrease (41.5% in the first grade and 27.0% in the fourth grade).

• (The)Korea Educational Review
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• v.18 no.1
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• pp.283-302
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• 2012

Multicultural families have literally started to settle in Korea since the late 1980s, yet it was not until the middle of 2000 that multicultural education was actually arisen with its full-scale discussions. Domestic studies on multicultural education have now remarkably been conducted in various aspects and points of views, but with no certain level of collective and comprehensive analysis yet. To seek Korean way of finding out appropriate solutions to its multicultural society, a contemporary major trend in the world, it is necessary to keep developing the theory and practice in Korean multicultural education with constructive criticism over the development. In this thesis, the research trends and characteristics of Korea multicultural education are analyzed according to the three categories: the times of the study, the subjects of the study, and the themes of the study. The analysis of the study themes, in particular, is done based on the four core areas presented by Bennett: equity pedagogy, curriculum reform, multicultural competence, and societal equity. Furthermore, the analysis includes the five additional Korean sub-categories, which are also acquired in the process of our analysis of the thesis: multiculturalism, global multicultural education, counselling research, measurement development, and citizenship education, added to Bennett's three sub-ones of each area. Overall, based on the analysis data, this study investigates further improvements and subsequent research themes in the following researches on Korean multicultural education.

• 한국노년학
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• v.28 no.4
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• pp.1179-1200
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• 2008

Knowledge about somatization (somatic manifestation of psychological distress symptoms) among immigrant populations is limited. While several studies have recognized somatization as a culturally distinctive expression of depression amongst older Korean immigrant population, somatization has not been incorporated into the comprehensive empirical model for depression of this population. In order to improve our general understanding of the phenomenon, the objective of this study is to empirically investigate principal contributing factors of somatization as well as inter-relationships among them. Data were collected from a cross-sectional community survey of 234 older Korean immigrants ($$age{\geq_-}55$$) in the New York metropolitan area. The statistical methodology employed a robust hierarchical regression procedure that iteratively downweights outliers. The results indicated that living arrangement, greater numbers of physical illnesses, and depression were significant explanatory factors of somatization. Furthermore, physical illness had a significant joint effect with perception of health on somatization, which confirms that positive perception of health exerts a moderating effect on the relationship between physical illness and somatization. The knowledge obtained from this study will contribute toward extending our knowledge on somatization and implementing more culturally sensitive mental health services for this population.

• Journal of radiological science and technology
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• v.28 no.4
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• pp.317-325
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• 2005

The recent medical treatment guidelines and the development of information technology make hospitals reduce the expense in surrounding environment and it requires improving the quality of medical treatment of the hospital. That is, with the new guidelines and technology, hospital business escapes simple fee calculation and insurance claim center. Moreover, MIS(Medical Information System), PACS(Picture Archiving and Communications System), OCS(Order Communicating System), EMR(Electronic Medical Record), DSS(Decision Support System) are also developing. Medical Information System is evolved toward integration of medical IT and situation si changing with increasing high speed in the ICT convergence. These changes and development of ubiquitous environment require fundamental change of medical information system. Mobile medical information system refers to construct wireless system of hospital which has constructed in existing environment. Through RFID development in existing system, anyone can log on easily to Internet whenever and wherever. RFID is one of the technologies for Automatic Identification and Data Capture(AIDC). It is the core technology to implement Automatic processing system. This paper provides a comprehensive basic review of RFID model in Korea and suggests the evolution direction for further advanced RFID application services. In addition, designed and implemented DB server's agent program and Client program of Mobile application that recognized RFID tag and patient data in the ubiquitous environments. This system implemented medical information system that performed patient data based EMR, HIS, PACS DB environments, and so reduced delay time of requisition, medical treatment, lab.