• YAKHAK HOEJI
• /
• v.34 no.4
• /
• pp.277-281
• /
• 1990

The isolation and identification of an antibacterial component, from Polygoni Radix against a cariogenic bacterium Streptococcus mutans OMZ 176, were carried out for development of anticariogenic agents. The bioactive component was identified to be emodin. The minimal inhibitory concentration (MIC) of emodin was $100\;{\mu}g/ml$ against S. mutans OMZ 176. The bioactive component emodin weakly inhibited ${\beta}-lactamase$ activity with the inhibition ratio of 1.7, 4.3 and 7.6% at the concentration of 50, 100, and 200 uM, respectively. Emodin exhibited slight phototoxicity when analysed by the photohemolysis method.

• Steel and Composite Structures
• /
• v.52 no.1
• /
• pp.1-14
• /
• 2024

This paper introduces a system allows for seismic isolation of the pallet from the rack in the down-aisle direction, occupies minimal vertical space (5 cm) and ±7.5 cm of deformation range. A conceptual model of the isolation system is presented, leading to a constitutive equation governing its behavior. A first experimental campaign studying the response of the isolation system's components was conducted to calibrate the parameters of its constitutive equation. A second experimental campaign evaluated the response of the isolation system with mass placed on it, subjected to cyclic loading. The results of this second campaign were compared with the numerical predictions using the pre-calibrated constitutive equation, allowing a double-blind validation of the constitutive equation of the isolation system. Finally, a numerical evaluation of the isolation system subjected to a synthetic earthquake of one component. This evaluation allowed verifying attributes of the proposed isolation system, such as its self-centering capacity and its effectiveness in reducing the absolute acceleration of the isolated mass and the shear load transmitted to the supporting beams of the rack.

• Tunnel and Underground Space
• /
• v.9 no.3
• /
• pp.175-184
• /
• 1999

Systematic measurements in the field are the key component in the design process to ensure that optimal and safe designs result. The instruments installed at the Waste Isolation Pilot Plant, a underground nuclear waste repository in U.S., for measuring rock deformation was reviewed. Also discussions about installation and measurement for better understanding the complex time-dependent deformational behavior of underground excavation were made.

• Structural Engineering and Mechanics
• /
• v.20 no.3
• /
• pp.347-362
• /
• 2005

The input energy to a base-isolated (BI) building during an earthquake is considered and formulated in the frequency domain. The frequency-domain approach for input energy computation has some notable advantages over the conventional time-domain approach. Sensitivities of the input energy to the BI building are derived with respect to uncertain parameters in the base-isolation system. It is demonstrated that the input energy can be of a compact form via the frequency integration of the product between the input component (Fourier amplitude spectrum of acceleration) and the structural model component (so-called energy transfer function). With the help of this compact form, it is shown that the formulation of earthquake input energy in the frequency domain is essential for deriving the sensitivities of the input energy to the BI building with respect to uncertain parameters. The sensitivity expressions provide us with information on the most unfavorable combination of the uncertain parameters which leads to the maximum energy input.

• The Transactions of the Korean Institute of Power Electronics
• /
• v.5 no.6
• /
• pp.544-551
• /
• 2000

In this paper, 3-phase hybrid series active power filter for compensate current harmonics, voltage drop and unbalanced voltage in the network presented. The proposed system is implemented with a space vector modulation voltage source inverter and a high pass filter connected in parallel to the power system. Here the load is six-pulses thyristor rectifier. The phase angle detected in order to generation reference voltage at load terminal is synchronized with the positive sequence component of the unbalanced source by using symmetrical component transformation. The proposed system has an function harmonic isolation between source and load, voltage regulation, and unbalance compensation. Therefore, what the power system is improved quality, the source current is maintained as a nearly sinusoidal waveform and the load voltage is regulated with a rated voltage regardless of the source variation condition. To verify the validity of the proposed compensating system, the computer simulation and experiment are carried out.

• Structural Monitoring and Maintenance
• /
• v.5 no.3
• /
• pp.325-343
• /
• 2018

This study aims to propose a performance-based design method of a novel passive base isolation system, BIO isolation system, which is inspired by an energy dissipation mechanism called 'sacrificial bonds and hidden length'. Fragility functions utilized in this study are derived, indicating the probability that a component, element, or system will be damaged as a function of a single predictive demand parameter. Based on PEER framework methodology for Performance-Based Earthquake Engineering (PBEE), a systematic design procedure using performance and fragility objectives is presented. Base displacement, superstructure absolute acceleration and story drift ratio are selected as engineering demand parameters. The new design method is then performed on a general two degree-of-freedom (2DOF) structure model and the optimal design under different seismic intensities is obtained through numerical analysis. Seismic performances of the biologically inspired (BIO) isolation system are compared with that of the linear isolation system. To further demonstrate the feasibility and effectiveness of this method, the BIO isolation system of a 4-storey reinforced concrete building is designed and investigated. The newly designed BIO isolators effectively decrease the superstructure responses and base displacement under selected earthquake excitations, showing good seismic performance.

• YAKHAK HOEJI
• /
• v.34 no.2
• /
• pp.106-111
• /
• 1990

The isolation and identification of an antibacterial component, from the leaves of Liriodendron tulipifera. K. Kotch against a cariogenic bacterium Streptococcus mutans OMZ 176, were carried out for developing of anticariogenic agents. The bioactive component was elucidated as ${\beta}-liriodenolide$, which was isolated newly from the leaves of L. tulipifera. The minimal inhibitory concentration (MIC) of ${\beta}-liriodenolide$ was $100\;{\mu}g/ml$ and the antibacterial activity was stronger than that of berberine. ${\beta}-Liriodenolide$ inhibited ${\beta}-lactamase$ activity, 50, 100 and $200\;{\mu}M$ ${\beta}-liriodenolide$ did ${\beta}-lactamase$ activity as 0.7, 3.5 and 19.7%, respectively. The toxicity of ${\beta}-liriodenolide$ was not found with the method of photohemolysis.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.16 no.1
• /
• pp.127-132
• /
• 2012

In this paper, the edge effects of proposed structure in active region for high voltage in shallow trench isolation for very large integrated MOSFET were simulated. Shallow trench isolation (STI) is a key process component in CMOS technologies because it provides electrical isolation between transistors and transistors. As a simulation results, shallow trench structure were intended to be electric functions of passive, as device dimensions shrink, the electrical characteristics influence of proposed STI structures on the transistor applications become stronger the potential difference electric field and saturation threshold voltage.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.17 no.2
• /
• pp.89-95
• /
• 2013

Structures in a nuclear power system are designed to be elastic even under an earthquake excitation. However a structural component such as an isolator shows inelastic behavior inherently. For the seismic assessment of nonlinear structures, response history analysis should be performed. In this study, the response of base isolation system was analyzed by response history analysis for the seismic performance assessment. Firstly, several seismic assessment criteria for a nuclear power plant structure were reviewed for the nonlinear response history analysis. Based on these criteria, the spectrum matched ground motion generation method modifying a seed earthquake ground motion time history was adjusted. Using these spectrum matched accelerograms, the distribution of displacement responses of the simplified base isolation system was evaluated. The resulting seismic responses excited by the modified ground motion time histories and the synthesized time history generated by stochastic approach were compared. And the response analysis of the base isolation system considering the different intensities in each orthogonal direction was performed.

• Journal of Society of Preventive Korean Medicine
• /
• v.7 no.1
• /
• pp.133-138
• /
• 2003

It is well known that Dioscoreae Rhizoma tonifies and benefits the Spleen and Stomach, benefits the Lung and nourishes the Kidney. A major component isolated from this herb consist of dioscin, diosgenin, allantoin, starch, alanin, mucilage, choline, amylase, and glycoprotein. In this study, we aimed to measure the content of allantoin, one of major component, to determine the quality of Dioscoreae Rhizoma.