• 한국엔터테인먼트산업학회논문지
• /
• 제13권8호
• /
• pp.357-365
• /
• 2019

본 연구의 목적은 대사증후군을 가진 사람의 성별, 연령에 따른 건강관련 삶의 질(EQ-5D)의 차이를 확인하는 것이다. 국민건강영양조사(KNHANES VI-2)에 응답한 5,021명의 자료를 이용하여 대사증후군 판정을 하였으며, IBM SPSS STATISTICS 25.0의 복합표본분석을 적용한 빈도분석, 교차분석과 Complex Samples GLM과 Complex Samples t-test를 사용하였다. 연구결과 EQ-5D 지수에 있어서 남성이 여성보다 다소 높았다(p<.001). 연령별로는 청장년(19~39세), 중년(40~65세), 노년(65세 이상)의 순서로 높게 확인되었다(p<.001). 대사증후군 여부로는 대사증후군에 속하지 않는 경우가 대사증후군을 가진 경우보다 추정치가 높게 나타났으나 통계적으로 유의하지는 않았다. 대사증후군 여부로는 대사증후군이 있는 경우에 그렇지 않은 경우보다 건강관련 삶의 질이 추정치에서 낮음으로 나타났으나 통계적으로 유의하지 않았다(p>.05). 한편, 전체 모집단(population)에서 성인을 대상으로 복합표본을 적용한 독립표본 t 검정(Complex Samples Independent t-test)을 통해 성별 간 대사증후군 유병여부에 따른 EQ-5D는 여성의 경우 대사증후군에 속하지 않은 경우가 대사증후군에 속하는 경우 보다 높은 지수가 확인되었으며 통계적으로 유의한 차이가 확인되었다(p<.01).

• Journal of Industrial and Engineering Chemistry
• /
• 제67권
• /
• pp.461-468
• /
• 2018

A highly sensitive, selective and rapid method for the determination of lead based on the reaction of lead (II) with 5-(4'-chlorophenylazo)-6-hydroxypyrimidine-2,4-dione (CPAHPD) and the solid phase extraction of the Pb(II)-CPAHPD complex with Amberlite XAD-2000 was developed, in the presence of pH 5.6 buffer solution and Triton X-114 medium. CPAHPD reacts with lead to form a violet complex with a molar ratio of 2:1 (CPAHPD to lead). This complex was enriched by the solid phase extraction with Amberlite XAD-2000. An enrichment factor of 500 was obtained by elution of the complex from the resin with a minimal amount of isopentyl alcohol(0.2 mL). In isopentyl alcohol medium,the molar absorptivity of the complex is $1.13{\times}10^6L\;mol^{-1}cm^{-1}$ at 647 nm. Beer's law is obeyed in the range of $5.0-160ng\;mL^{-1}$ in the measured solution. The relative standard deviation for 10 replicate samples of $50ng\;mL^{-1}$ level is 1.26%. The detection and quantification limits reaches 1.5 and $4.7ng\;mL^{-1}$ in the original samples. The presented procedure was successfully applied for determination of lead content in real samples such as vegetables, waters, biological and soil samples with satisfactory results.

• Bulletin of the Korean Chemical Society
• /
• 제28권12호
• /
• pp.2293-2298
• /
• 2007

In this study, a dithizone extraction technique involving purge & trap GC-MS was developed for the determination of methylmercury in biological samples, especially blood and fish. After alkaline digestion, methylmercury in biological samples was extracted into dithizone and back-extracted into aqueous sulfide solution. The extracted methylmercury was converted to the volatile ethyl derivative, purged and trapped onto a solid-phase collection medium, and then introduced into the GC-MS system. The determined MDLs of the established method were 0.9 ng·g?1 for biological samples and its accuracy and precision were found to be 93% and 3.8%, respectively. The method was validated by analysis of CRMs such as SRM 966, BCR 463 and IAEA 407 and all analytical results were within certified ranges with average RSDs of less than 6%. The analytical results of field-sampled fish also showed that the method can be successfully used as an alternative for commonly used distillation method followed by GC-CVAFS detection.

• Bulletin of the Korean Chemical Society
• /
• 제27권4호
• /
• pp.563-567
• /
• 2006

The application of a synergistic solvent extraction by the formation of ternary complex with pyrocatechol violet (PV) and benzalkonium chloride (BC) was studied for determination of trace Zn(II) in water samples. The pH of sample solution and the amount of PV and BC added were optimized for the formation of the stable complex, a proper solvent was selected for the effective extraction, and the concentration of nitric acid was fixed for the back extraction of the complex from the solvent. After the ionic strength of 100 mL sample solution was adjusted to 0.1 M by adding NaCl and the pH was fixed at 9 with a carbonate buffer, 1.0 mL of 2% PV solution was added to form Zn(II)-PV complex then the Zn(II)-PV/BC ternary complex was made by adding 1.0 mL of 10% BC solution. The ternary complex was extracted into 10 mL of MIBK. And the ternary complex was back-extracted with 10 mL of 1.0 mol/L nitric acid to determine Zn(II) by a flame atomic absorption spectrophotometer (flame-AAS). The interference of concomitant ions on the extraction of Zn(II) was investigated. This procedure was applied to the analysis of three real samples such as Dalbang-dam water, laboratory tap water and Jungnajin seawater. The recoveries of Zn(II) in spiked samples were 86.58-104.1%.

• 한국대기환경학회지
• /
• 제13권3호
• /
• pp.207-214
• /
• 1997

We collected airborne complex mixtures in a industrial area of Yeochun, and examined whether these complex mixtures could affect gap junctional intercellular communication (GJIC) in a cultured WBF-344 rat liver epithelial cells (LEC). Since the reduction of GJIC plays an important role in chemical carcinogenesis, measurement of changes of GJIC is a meaningful method to screen carcinogenicity of these mixtures. High and low volume samples were dissolved in dimethyl sulfoxide (DMSO) and tested. Blank filter extractions were also examined for exclud-ing possible toxicity of filter itself, and TPA (12-O-tetradecanoylphorbol-13-acetate) and DMSO were used as positive and negative control, respectively. When the cells were exposed to samples at concentration below that required to maintain rather than 85% cell viability based on the result of neutral red uptake assay, maximal inhibition of GJIC was observed at 1hr after treatment with both high and low volume samples by scrape-loading dye transfer assay. In fluorescence recovery after photobleaching assay, recovery rates via gap junctions were 33%/min in high volume sample and 62%/min in low volume sample. In together, airborne samples collected in Yeochun inhibited GJIC in a cultured WBF-344 rat LEC. These results suggest airborne samples tested in this experiment may attribute to cause a certain type and degree of cancers in in vivo when exposured for some periods.

• 보건의료산업학회지
• /
• 제8권2호
• /
• pp.139-148
• /
• 2014

The purpose of this study was to analyze the factors affecting the unmet dental needs of Koreans. In relation to the subjects and methodology for this study, the data from the 5th national health nutrition survey which had been conducted between 2010 and 2012 were analyzed by using the PASW statistics 18.0 (SPSS Inc., Chicago, IL, USA), a statistical program, through the frequency analysis of complex samples, cross analysis of complex samples, and logistics regression analysis of complex samples. The results of analysis showed that the rate of unmet dental needs stood at 35.3% of all subjects. Moreover, to determine the factors related to the unmet dental needs, the logistics regression analysis of complex samples was conducted. The results of analysis showed that the demographic and socio-economic factors and oral health condition factors had relationship with unmet dental needs. It is necessary to consider all the objective dental treatments that reflect specific dental diagnosis from a comprehensive standpoint.

• 연구논문집
• /
• 통권33호
• /
• pp.175-182
• /
• 2003

In this study, the wear resistance of the complex powder diffusion treated KS STD 61 has been investigatived. KS STD 61 tool steel was pretreated in quenching and tempering processes to obtain the tempered martensitic microstructure. The samples were packed with complex powder in steel pot($\Phi$90x60mm) and heated in a box furnace. the complex powder diffusion treatment are carried out at $540^{\circ}C$, $520^{\circ}C$, $500^{\circ}C$ for 40min, 1.5hr and 2.5hr. The microstructure, microhardness, wear resistance, and coating layer thickness of the complex powder diffusion treated samples were investigation. The weight loss of as heat treated sample was 0.4mg and that of the complex powder treated at $540^{\circ}C$ for 2.5hr was 0.17mg. These result means that the wear resistance of tool steels can be easily improved by the powder diffusion process at conventional tempering treatment temperature.

• 한국자원식물학회지
• /
• 제20권3호
• /
• pp.226-233
• /
• 2007

To develop a clinically available saponin- or sapogenin complex from Oriental medicines, the EtOH extract (KPRG-A) was obtained by extracting from the four crude drugs, Kalopanacis Cortex, Platycodi Radix, Rubi Fructus and Glycyrrhizae Radis. The BuOH fraction (KPRG-B), a crude saponin complex, was prepared by fractionating KPRG-A, which were further completely hydrolyzed to afford the sapogenin complex (KPRG-D). In an attempt to find the antinoicpetive effects of the saponin complex and sapogenin complex, KPRG-C, and -D, were assayed by writhing-, hot plate-, and tail-flick tests using mice or rats. The three samples were also subjected to antiiflammatory tests using serotonin-induced and carrageenan-induced hind paw edema mice and rats, respectively. The three samples significantly reduced inflammations and pains of the experimental animal. The potency were found in the order of KPRG-D> KPRG-C> KPRG-B. The most active sample, KPRG-D, caused no death, no body increase or no anatomical pathlogic change even at 2,000 mg/kg dose. These results suggest that a sapogenin complex, KPRG-D, which was found to contain mainly hederagenin, platycodigenin, polygalacic acid, 23-hydroxytormentic acid, glycyrrhetic acid together with minor triterpene acids, could be a potential candidate for antiinflammatory therapeutics.

• 한국식생활문화학회지
• /
• 제32권3호
• /
• pp.235-243
• /
• 2017

We investigated the antioxidant, physicochemical, and sensory characteristics of dried type sodium-reduced Bibimbap using dandelion complex powder (DCP). DCP is known to add moisture to the skin and relieve symptoms of atopic dermatitis. The sodium content of the standard sample was 1,110.87 mg per serving. The sodium was significantly reduced by 30%, resulting in 762.62 mg of sodium for the reduced sodium group (p<0.05). The ash contents of the standard sample group with DCP showed the highest value (3.17%) in all samples and was affected by minerals of DCP (p<0.05). The total flavonoid contents and ABTS radical scavenging activity, indicators of antioxidant, anticancer and antibacterial activities, showed significantly high activities with addition of DCP (p<0.05). In the sensory results, bulgogi and savory flavor of the samples with DCP showed significantly higher values, and samples with DCP received the highest scores for after-taste. All samples were confirmed to be microbiologically safe according to the food code applied to food manufacturers. Pathogenic microorganisms tests were either negative or not detected in all samples.

• Parasites, Hosts and Diseases
• /
• 제51권4호
• /
• pp.461-466
• /
• 2013

From May to June 2012, a waterborne outbreak of 124 cases of cryptosporidiosis occurred in the plumbing system of an older high-rise apartment complex in Seoul, Republic of Korea. The residents of this apartment complex had symptoms of watery diarrhea and vomiting. Tap water samples in the apartment complex and its adjacent buildings were collected and tested for 57 parameters under the Korean Drinking Water Standards and for additional 11 microbiological parameters. The microbiological parameters included total colony counts, Clostridium perfringens, Enterococcus, fecal streptococcus, Salmonella, Shigella, Pseudomonas aeruginosa, Cryptosporidium oocysts, Giardia cysts, total culturable virus, and Norovirus. While the tap water samples of the adjacent buildings complied with the Korean Drinking Water Standards for all parameters, fecal bacteria and Cryptosporidium oocysts were detected in the tap water samples of the outbreak apartment complex. It turned out that the agent of the disease was Cryptosporidium parvum. The drinking water was polluted with sewage from a septic tank in the apartment complex. To remove C. parvum oocysts, we conducted physical processes of cleaning the water storage tanks, flushing the indoor pipes, and replacing old pipes with new ones. Finally we restored the clean drinking water to the apartment complex after identification of no oocysts.